+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptomyces tuirus

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E GCM10017668_02510 putative polyketide beta-ketoacyl synthase 1 K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E GCM10017668_02500 putative polyketide beta-ketoacyl synthase 2 K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E GCM10017668_02490 putative acyl carrier protein K14669 whiEV; minimal PKS acyl carrier protein E GCM10017668_02480 putative polyketide cyclase K14670 whiEVI; aromatase E GCM10017668_02470 hypothetical protein K14671 whiEVII; cyclase E GCM10017668_38090 polyketide synthase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E GCM10017668_38110 fabF; beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E GCM10017668_38120 actinorhodin polyketide putative beta-ketoacyl synthase 2 K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E GCM10017668_38130 actinorhodin polyketide synthase acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein D Nonaketide PKS E GCM10017668_38110 fabF; beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E GCM10017668_38120 actinorhodin polyketide putative beta-ketoacyl synthase 2 K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E GCM10017668_38130 actinorhodin polyketide synthase acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein D Decaketide PKS E GCM10017668_38110 fabF; beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E GCM10017668_38120 actinorhodin polyketide putative beta-ketoacyl synthase 2 K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E GCM10017668_38130 actinorhodin polyketide synthase acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein B Type III PKS C Plant type C Fungal type C Bacterial type D GCM10017668_08020 1,3,6,8-tetrahydroxynaphthalene synthase K19580 rppA; 1,3,6,8-tetrahydroxynaphthalene synthase [EC:2.3.1.233] D GCM10017668_67980 polyketide synthase K16232 gcs; germicidin synthase D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D GCM10017668_62320 protein mbtH K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C GCM10017668_55660 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C GCM10017668_67040 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C GCM10017668_35600 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C GCM10017668_66050 microsomal epoxide hydrolase K21159 sgcF; epoxide hydrolase C GCM10017668_02520 16.7 kDa protein in whiE locus K14673 whiEII; putative monooxygenase C GCM10017668_38100 16.7 kDa protein in whiE locus K14673 whiEII; putative monooxygenase C GCM10017668_02540 hypothetical protein K14672 whiEVIII; putative polyketide hydroxylase C GCM10017668_37950 FAD-dependent oxidoreductase K14672 whiEVIII; putative polyketide hydroxylase C GCM10017668_38040 FAD-dependent oxidoreductase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C GCM10017668_37980 methyltransferase K20421 ncsB1; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase [EC:2.1.1.303] C GCM10017668_02460 O-methyltransferase K14251 oxyF; C-methyltransferase [EC:2.1.1.-] B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C GCM10017668_45770 hypothetical protein K14628 actVI2; enoyl reductase # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase B Others C GCM10017668_03330 alpha-hydroxy-acid oxidizing enzyme K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024