+F Repair protein KO
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DNA Repair and Recombination Proteins - Staphylococcus aureus subsp. aureus ED133
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SAOV_2591c methylated-DNA-protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SAOV_0726 deoxyribodipyrimidine photolyase, putative K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SAOV_0615 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SAOV_2386 probable 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SAOV_1895 probable A/G-specific adenine glycosylase DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SAOV_1460 endonuclease III-like protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SAOV_2535c MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SAOV_1774 putative hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SAOV_1092 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SAOV_1941c hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SAOV_2591c methylated-DNA-protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SAOV_0726 deoxyribodipyrimidine photolyase, putative K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SAOV_0615 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SAOV_2386 probable 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SAOV_1895 probable A/G-specific adenine glycosylase DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SAOV_1653 tag; DNA-3-methyladenine glycosidase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SAOV_1677 probable formamidopyrimidine DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SAOV_1460 endonuclease III-like protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SAOV_1557 endonuclease K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E SAOV_1633 single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SAOV_2006 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SAOV_1678 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SAOV_0796 exinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E SAOV_0795 exinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E SAOV_1143 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E SAOV_2007 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SAOV_1678 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SAOV_2006 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SAOV_0577 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SAOV_0578 rpoC; DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SAOV_2262c DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SAOV_2169c rpoE; probable DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F SAOV_1213 probable DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SAOV_0525 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SAOV_1297 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E SAOV_1141 DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E SAOV_1298 hexB; DNA mismatch repair protein HexB K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E SAOV_1524 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SAOV_1523 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SAOV_1690 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SAOV_1266 DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E SAOV_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SAOV_1586 conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SAOV_0505 DNA polymerase III, delta prime subunit, putative K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SAOV_1993 probable DNA polymerase III alpha chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SAOV_0496 DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SAOV_2006 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SAOV_2007 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SAOV_0290 Single-stranded DNA-binding protein, phage associated K03111 ssb; single-strand DNA-binding protein
E SAOV_1081 single strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
E SAOV_0390 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SAOV_2138c single strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
E SAOV_1956c Single-stranded DNA-binding protein, phage associated K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SAOV_1617 probable deoxyribonuclease K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SAOV_1287 recA; recombinase A protein K03553 recA; recombination protein RecA
E SAOV_1639 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SAOV_1638 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SAOV_1215 primosomal protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SAOV_1359 exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E SAOV_1358 probable exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SAOV_1287 recA; recombinase A protein K03553 recA; recombination protein RecA
E SAOV_0561 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E SAOV_0004 recF; recF protein K03629 recF; DNA replication and repair protein RecF
E SAOV_1230 ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SAOV_2254c ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SAOV_1633 single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SAOV_1566 probable recombination protein K03584 recO; DNA repair protein RecO (recombination protein O)
E SAOV_0498 recombination protein RecR K06187 recR; recombination protein RecR
E SAOV_1520 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E SAOV_1457 recU; recombination protein U K03700 recU; recombination protein U
E SAOV_1639 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SAOV_1638 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E SAOV_0914 ATP-dependent nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E SAOV_0913 ATP-dependent nuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E SAOV_1359 exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E SAOV_1358 probable exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SAOV_0006 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SAOV_0005 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SAOV_1252 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SAOV_1479 hup; DNA-binding protein II K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SAOV_1633 single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SAOV_1566 probable recombination protein K03584 recO; DNA repair protein RecO (recombination protein O)
F SAOV_0498 recombination protein RecR K06187 recR; recombination protein RecR
F SAOV_2006 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F SAOV_1488 probable ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SAOV_0755 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SAOV_0796 exinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F SAOV_0795 exinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SAOV_1994 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SAOV_1374 DNA-damage repair protein K03502 umuC; DNA polymerase V
C Other SOS response factors
D SAOV_1287 recA; recombinase A protein K03553 recA; recombination protein RecA
D SAOV_1352c dinR; DNA damage SOS regulatory repressor protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D SAOV_1520 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D SAOV_0290 Single-stranded DNA-binding protein, phage associated K03111 ssb; single-strand DNA-binding protein
D SAOV_1081 single strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D SAOV_0390 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SAOV_2138c single strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D SAOV_1956c Single-stranded DNA-binding protein, phage associated K03111 ssb; single-strand DNA-binding protein
D SAOV_1899 regulatory protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D SAOV_1140 DNA-dependent DNA polymerase beta chain K02347 polX; DNA polymerase (family X)
C DNA helicases
D SAOV_1463 dinG; probable ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SAOV_2535c MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SAOV_1774 putative hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SAOV_1092 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SAOV_1941c hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SAOV_0767 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SAOV_0768 nrdF; ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D SAOV_1691 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024