+C Two-component system KO
#
Two-Component System - Stigmatella aurantiaca
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C STAUR_2103 Sensor protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C STAUR_5626 Sensor protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C STAUR_8136 Sensor protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C STAUR_0727 phoP; DNA-binding response regulator PhoP K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
C STAUR_4909 phoP2; DNA-binding response regulator PhoP2 K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
C STAUR_5625 phoP1; DNA-binding response regulator PhoP1 K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
C STAUR_5628 phoB; Phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
C STAUR_0728 phoR; Sensor protein K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C STAUR_0220 kdpD; Sensor protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
C STAUR_0581 Sensor protein K07654 mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C STAUR_1782 Sensor protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C STAUR_1875 Sensor protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C STAUR_6025 Sensor protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C STAUR_1269 Response regulator K02483 K02483; two-component system, OmpR family, response regulator
C STAUR_3096 Two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C STAUR_5903 Two-component response regulator K02483 K02483; two-component system, OmpR family, response regulator
C STAUR_6024 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C STAUR_7557 Response regulator K02483 K02483; two-component system, OmpR family, response regulator
C STAUR_7565 Response regulator K02483 K02483; two-component system, OmpR family, response regulator
#
ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
C STAUR_4526 Sensor histidine kinase K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
#
ASpo family
B KinABCDE-Spo0FA (sporulation control)
#
ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
#
ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B BtsS-BtsR (pyruvate reutilization)
B PyrS-PyrR (pyruvate reutilization)
B Unclassified
C STAUR_8302 Two component transcriptional regulator, LytTR family K02477 K02477; two-component system, LytTR family, response regulator
#
ANtrC family
B GlnL-GlnG (nitrogen regulation)
C STAUR_0303 Sigma-54 dependent transcriptional regulator, Fis family K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
C STAUR_8305 Sigma-54 dependent transcriptional regulator, Fis type K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C STAUR_0773 Sensor protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C STAUR_1707 Sensor protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C STAUR_3807 Sensor protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C STAUR_6693 Sensor protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C STAUR_7971 sensor protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C STAUR_0772 Two component transcriptional regulator, Fis family K07713 zraR; two-component system, NtrC family, response regulator HydG
C STAUR_1862 sasR; Sigma-54 dependent DNA-binding response regulator SasR K07713 zraR; two-component system, NtrC family, response regulator HydG
C STAUR_3197 Two component transcriptional regulator, Fis type K07713 zraR; two-component system, NtrC family, response regulator HydG
C STAUR_4506 Mutant NtrC-like activator K07713 zraR; two-component system, NtrC family, response regulator HydG
C STAUR_6547 Sigma-54 dependent transcriptional regulator, Fis family K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
C STAUR_1706 frgC; Sigma-54 dependent DNA-binding response regulator FrgC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C STAUR_1783 nla28; Sigma-54 dependent DNA-binding response regulator Nla28 K07714 atoC; two-component system, NtrC family, response regulator AtoC
C STAUR_3648 actB; Sigma-54 activator protein ActB K07714 atoC; two-component system, NtrC family, response regulator AtoC
C STAUR_4072 Sigma-54 dependent DNA-binding response regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C STAUR_5890 mrpB; Sigma-54 dependent DNA-binding response regulator MrpB K07714 atoC; two-component system, NtrC family, response regulator AtoC
C STAUR_6446 PilR protein (Sigma-54 dependent DNA-binding response regulator) K07714 atoC; two-component system, NtrC family, response regulator AtoC
C STAUR_7659 Sigma-54 dependent transcriptional regulator, Fis family K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
C STAUR_6455 Sensor protein K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C STAUR_6454 pilR; Pilin regulatory protein PilR K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
C STAUR_5454 RNA polymerase sigma factor 54 K07715 glrR; two-component system, NtrC family, response regulator GlrR
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
C STAUR_0221 Sensor protein K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
C STAUR_0222 Sigma-54 dependent DNA-binding response regulator K11384 algB; two-component system, NtrC family, response regulator AlgB
B HupT-HupR (hydrogenase synthesis regulation)
C STAUR_0444 Sigma-54 dependent transcriptional regulator, Fis type K19641 hupR; two-component system, NtrC family, response regulator HupR/HoxA
B Unclassified
C STAUR_0493 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_1167 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_1481 sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_1669 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_1775 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_1837 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_2886 sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_2931 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_3406 asgA; A-signal transduction regulator, AsgA K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_4092 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_4443 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_4550 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_4649 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_4763 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_4800 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_4907 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_5194 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_5209 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_5256 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_5807 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_5829 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_6072 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_6447 pilS; Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_6644 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_7219 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_7487 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_7822 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C STAUR_8018 Sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
#
ACheA family
B CheA-CheYBV (chemotaxis)
C STAUR_0489 Response regulator receiver, CheW-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_0860 cheA; chemotaxis protein, CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_0871 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_1221 difE; DifE-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_3423 cheA4; Sensor histidine kinase/response regulator CheA4 K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_4587 frzE; Gliding motility regulatory protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_4722 Chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_5607 CheW-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_5916 Sensor histidine kinase/response regulator K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_6706 Chemotaxis sensor histidine kinase/response regulator K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C STAUR_0859 chemotaxis protein CheY-like protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C STAUR_1220 difD; DifD-like protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C STAUR_5601 cheY; Chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C STAUR_5608 Chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C STAUR_6691 Response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C STAUR_6710 response regulator, CheY-like protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C STAUR_6741 Response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C STAUR_0490 Chemotaxis response regulator protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_0865 Chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_0870 Chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_3021 CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_3806 cheB; Chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_4586 frzG; Protein-glutamate methylesterase FrzG K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_5602 cheB1; Chemotaxis response regulator protein-glutamate methylesterase 1 K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_5660 Chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_5915 cheB2; Chemotaxis response regulator protein-glutamate methylesterase 2 K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_6705 Chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_7564 CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_7573 Protein-glutamate methylesterase domain protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C STAUR_7112 Sensor protein K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
C STAUR_7562 Methylase of chemotaxis methyl-accepting protein, CheR-type K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
B ChpA-ChpB/PilGH (chemosensory)
C STAUR_3421 cheY4; Response regulator CheY4 K02657 pilG; twitching motility two-component system response regulator PilG
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
C STAUR_7006 Sensor protein K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
C STAUR_8015 Sensor protein K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
#
ACell cycle family
B PleC-PleD (cell fate control)
C STAUR_2325 Response regulator K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
C STAUR_6916 Sensor protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C STAUR_7563 Sensor protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
B Hk1-Rrp1 (glycerol uptake and utilization)
#
ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
#
ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
#
AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C STAUR_1186 Sensor protein K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C STAUR_1187 DNA-binding response regulator, Fis type K15012 regA; two-component system, response regulator RegA
C STAUR_7968 redF; RedF protein K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
C STAUR_7903 Sensor protein K19621 phcS; two-component system, sensor histidine kinase PhcS [EC:2.7.13.3]
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C STAUR_0288 Sensor protein K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C STAUR_5413 Sensor protein K19694 chiS; two-component system, sensor histidine kinase ChiS
C STAUR_3490 Sensor protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C STAUR_6076 Sensor protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 8, 2024