+F Repair protein KO
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DNA Repair and Recombination Proteins - Staphylococcus aureus subsp. aureus 11819-97 (CA-MRSA)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MS7_2553 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MS7_0743 DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MS7_0570 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MS7_2362 DNA-3-methyladenine glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MS7_1903 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MS7_1408 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MS7_2496 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MS7_1792 ytkD; nucleoside triphosphatase YtkD K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MS7_1480 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MS7_2553 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MS7_0743 DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MS7_0570 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MS7_2362 DNA-3-methyladenine glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MS7_1903 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MS7_1672 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MS7_1696 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MS7_1408 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MS7_1574 nfo; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E MS7_1651 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MS7_1939 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MS7_1697 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MS7_0809 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E MS7_0808 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E MS7_1103 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E MS7_1940 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MS7_1697 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MS7_1939 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MS7_0532 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MS7_0533 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MS7_2244 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MS7_2146 DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F MS7_1168 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MS7_0480 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MS7_1253 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E MS7_1101 mutS2; mutS2 protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E MS7_1254 mutL; DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MS7_1541 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MS7_1540 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MS7_1709 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MS7_1222 polC; DNA polymerase III, alpha subunit, Gram-positive type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E MS7_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MS7_1604 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MS7_0461 DNA polymerase III subunits gamma and tau domain III family protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MS7_1929 exonuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MS7_0452 dnaX; DNA polymerase III, subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MS7_1939 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MS7_1940 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MS7_0596 single-stranded DNA-binding protein ssb K03111 ssb; single-strand DNA-binding protein
E MS7_0356 single-stranded DNA-binding protein ssb K03111 ssb; single-strand DNA-binding protein
E MS7_2113 single-stranded DNA-binding family protein K03111 ssb; single-strand DNA-binding protein
E MS7_2017 single-stranded DNA-binding protein ssb K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MS7_1635 viral (Super1) RNA helicase family protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MS7_1243 recA; protein RecA K03553 recA; recombination protein RecA
E MS7_1657 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MS7_1656 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MS7_1170 priA; primosomal protein N K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E MS7_1305 sbcC; nuclease sbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E MS7_1304 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MS7_1243 recA; protein RecA K03553 recA; recombination protein RecA
E MS7_0515 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MS7_0004 recF; DNA replication and repair RecF family protein K03629 recF; DNA replication and repair protein RecF
E MS7_1185 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MS7_1651 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MS7_1583 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MS7_0454 recR; recombination protein RecR K06187 recR; recombination protein RecR
E MS7_1537 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MS7_1405 recU; recombination protein U K03700 recU; recombination protein U
E MS7_1657 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MS7_1656 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E MS7_0922 addA; helicase-exonuclease AddAB, AddA subunit K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E MS7_0921 addB; helicase-exonuclease AddAB, AddB subunit K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E MS7_1305 sbcC; nuclease sbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E MS7_1304 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MS7_0006 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MS7_0005 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MS7_1208 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MS7_1427 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MS7_2019 recombinase, phage RecT family protein K07455 recT; recombination protein RecT
F MS7_0594 recombinase, phage RecT family protein K07455 recT; recombination protein RecT
F MS7_1651 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MS7_1583 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MS7_0454 recR; recombination protein RecR K06187 recR; recombination protein RecR
F MS7_1939 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MS7_0772 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MS7_1435 ATP-dependent DNA helicase, RecQ family protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MS7_0809 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F MS7_0808 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MS7_1930 impB/mucB/samB family protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MS7_1321 impB/mucB/samB family protein K03502 umuC; DNA polymerase V
C Other SOS response factors
D MS7_1243 recA; protein RecA K03553 recA; recombination protein RecA
D MS7_1298 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D MS7_1537 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MS7_0596 single-stranded DNA-binding protein ssb K03111 ssb; single-strand DNA-binding protein
D MS7_0356 single-stranded DNA-binding protein ssb K03111 ssb; single-strand DNA-binding protein
D MS7_2113 single-stranded DNA-binding family protein K03111 ssb; single-strand DNA-binding protein
D MS7_2017 single-stranded DNA-binding protein ssb K03111 ssb; single-strand DNA-binding protein
D MS7_1908 recX; regulatory protein recX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D MS7_1100 polX; DNA polymerase/3'-5' exonuclease PolX K02347 polX; DNA polymerase (family X)
C DNA helicases
D MS7_1411 putative ATP-dependent helicase, DinG family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MS7_2496 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MS7_1792 ytkD; nucleoside triphosphatase YtkD K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MS7_1480 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MS7_0782 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MS7_0783 ribonucleotide reductase, small chain family protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MS7_1710 DHH/DHHA1 domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024