+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptomyces violaceusniger

% ! APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E Strvi_2543 Beta-ketoacyl synthase K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E Strvi_2542 Beta-ketoacyl synthase K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E Strvi_2541 phosphopantetheine-binding protein K14669 whiEV; minimal PKS acyl carrier protein E Strvi_2540 cyclase/dehydrase K14670 whiEVI; aromatase E Strvi_2539 Polyketide synthesis cyclase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E Strvi_4077 beta-lactamase K05555 actIV; cyclase [EC:4.-.-.-] D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D Strvi_5198 MbtH domain protein K05375 mbtH; MbtH protein D Strvi_8793 MbtH domain protein K05375 mbtH; MbtH protein D Strvi_7975 MbtH domain protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D Strvi_8298 amino acid adenylation domain protein K02364 entF; L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72] C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C Strvi_5392 FAD-binding monooxygenase K16022 rif19; flavoprotein hydroxylase C Strvi_5921 FAD-binding monooxygenase K16022 rif19; flavoprotein hydroxylase C Strvi_7659 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C Strvi_2196 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C Strvi_1428 Epoxide hydrolase domain protein K21159 sgcF; epoxide hydrolase C Strvi_6005 Epoxide hydrolase domain protein K21159 sgcF; epoxide hydrolase C Strvi_6316 Epoxide hydrolase domain protein K21159 sgcF; epoxide hydrolase C Strvi_6384 Epoxide hydrolase domain protein K21159 sgcF; epoxide hydrolase C Strvi_8156 FAD-binding monooxygenase K14253 oxyE; 6-methylpretetramide 4-monooxygenase [EC:1.14.13.232] C Strvi_2544 Cupin 2 conserved barrel domain protein K14673 whiEII; putative monooxygenase C Strvi_2546 FAD-binding monooxygenase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C Strvi_6777 O-methyltransferase family 3 K16028 asm17; O-methyltransferase C Strvi_5877 O-methyltransferase family 3 K16028 asm17; O-methyltransferase C Strvi_2536 O-methyltransferase family 2 K14251 oxyF; C-methyltransferase [EC:2.1.1.-] B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C Strvi_6781 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein K16024 asm13; methoxymalonate biosynthesis protein C Strvi_5876 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein K16024 asm13; methoxymalonate biosynthesis protein C Strvi_5875 hypothetical protein K16025 asm14; methoxymalonate biosynthesis acyl carrier protein C Strvi_6780 hypothetical protein K16025 asm14; methoxymalonate biosynthesis acyl carrier protein C Strvi_4990 methoxymalonate biosynthesis protein K16025 asm14; methoxymalonate biosynthesis acyl carrier protein C Strvi_5874 acyl-CoA dehydrogenase domain-containing protein K16026 asm15; methoxymalonate biosynthesis protein C Strvi_6779 acyl-CoA dehydrogenase domain-containing protein K16026 asm15; methoxymalonate biosynthesis protein C Strvi_5873 FkbH like protein K16027 asm16; methoxymalonate biosynthesis protein C Strvi_6778 FkbH like protein K16027 asm16; methoxymalonate biosynthesis protein C Strvi_5872 Carbamoyltransferase K16035 asm21; 7-O-carbamoyltransferase [EC:2.1.3.-] C Strvi_5920 N-acetyltransferase K15466 rifF; amide synthase C Strvi_5385 N-acetyltransferase K15466 rifF; amide synthase C Strvi_8777 FMN-binding flavin reductase domain protein K14631 actVB; flavin reductase ActVB [EC:1.5.1.-] # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase C Strvi_8790 FMN-dependent alpha-hydroxy acid dehydrogenase K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] B Others C Strvi_7696 aminotransferase class V K04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17] C Strvi_8789 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C Strvi_8790 FMN-dependent alpha-hydroxy acid dehydrogenase K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C Strvi_5274 FMN-dependent alpha-hydroxy acid dehydrogenase K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C Strvi_7609 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024