+F Repair protein KO
#
DNA Repair and Recombination Proteins - Trichoplax adhaerens (placozoan)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D TRIADDRAFT_55441 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D TRIADDRAFT_25989 hypothetical protein K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
C BER (base exicision repair)
D DNA glycosylases
E TRIADDRAFT_58651 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TRIADDRAFT_5539 hypothetical protein K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E TRIADDRAFT_6342 hypothetical protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E TRIADDRAFT_30689 hypothetical protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E TRIADDRAFT_4611 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E TRIADDRAFT_5883 hypothetical protein K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E TRIADDRAFT_5178 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E TRIADDRAFT_54344 hypothetical protein K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E TRIADDRAFT_21050 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E TRIADDRAFT_62597 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E TRIADDRAFT_60990 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E TRIADDRAFT_21078 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E TRIADDRAFT_19413 hypothetical protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F TRIADDRAFT_18979 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F TRIADDRAFT_52972 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
F TRIADDRAFT_52194 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F TRIADDRAFT_30078 hypothetical protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F TRIADDRAFT_27613 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F TRIADDRAFT_56174 hypothetical protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E TRIADDRAFT_50695 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E TRIADDRAFT_24563 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E TRIADDRAFT_34086 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E TRIADDRAFT_50243 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E TRIADDRAFT_19032 hypothetical protein K10803 XRCC1; DNA-repair protein XRCC1
E TRIADDRAFT_57566 hypothetical protein K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E TRIADDRAFT_19546 hypothetical protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E TRIADDRAFT_18245 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E TRIADDRAFT_61257 hypothetical protein K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E TRIADDRAFT_59893 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E TRIADDRAFT_28268 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E TRIADDRAFT_19562 hypothetical protein K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E TRIADDRAFT_23639 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_32651 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_61586 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_61726 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_52698 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_13451 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_52697 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_61728 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_61732 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_61730 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRIADDRAFT_60629 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F TRIADDRAFT_2617 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F TRIADDRAFT_58050 hypothetical protein K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F TRIADDRAFT_50330 ring box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F TRIADDRAFT_24582 hypothetical protein K10609 CUL4; cullin 4
F TRIADDRAFT_18324 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F TRIADDRAFT_49721 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F TRIADDRAFT_58512 DNA directed RNA polymerase II polypeptide B K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F TRIADDRAFT_24132 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F TRIADDRAFT_26370 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F TRIADDRAFT_38029 expressed hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F TRIADDRAFT_50973 hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F TRIADDRAFT_50378 hypothetical protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F TRIADDRAFT_56007 hypothetical protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F TRIADDRAFT_19600 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F TRIADDRAFT_18503 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F TRIADDRAFT_59743 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F TRIADDRAFT_50330 ring box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F TRIADDRAFT_24582 hypothetical protein K10609 CUL4; cullin 4
F TRIADDRAFT_18324 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F TRIADDRAFT_59324 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F TRIADDRAFT_53632 hypothetical protein K10841 ERCC6; DNA excision repair protein ERCC-6
F TRIADDRAFT_58548 hypothetical protein K23720 UVSSA; UV-stimulated scaffold protein A
F TRIADDRAFT_49494 expressed hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E TRIADDRAFT_22911 hypothetical protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E TRIADDRAFT_50379 hypothetical protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E TRIADDRAFT_56692 hypothetical protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E TRIADDRAFT_57351 hypothetical protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E TRIADDRAFT_51576 hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E TRIADDRAFT_20428 hypothetical protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E TRIADDRAFT_30732 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E TRIADDRAFT_23304 hypothetical protein K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E TRIADDRAFT_53260 hypothetical protein K06634 CCNH; cyclin H
E TRIADDRAFT_52675 hypothetical protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E TRIADDRAFT_50671 hypothetical protein K07466 RFA1; replication factor A1
E TRIADDRAFT_32825 hypothetical protein K10739 RFA2; replication factor A2
D Other NER factors
E TRIADDRAFT_36524 expressed hypothetical protein K10847 XPA; DNA-repair protein complementing XP-A cells
E TRIADDRAFT_61989 hypothetical protein K10849 ERCC1; DNA excision repair protein ERCC-1
E TRIADDRAFT_50503 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E TRIADDRAFT_34086 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E TRIADDRAFT_58598 hypothetical protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E TRIADDRAFT_51283 hypothetical protein K03869 CUL3; cullin 3
E TRIADDRAFT_24784 hypothetical protein K10612 CUL5; cullin 5
E TRIADDRAFT_37956 expressed hypothetical protein K03872 ELOC; elongin-C
E TRIADDRAFT_59247 hypothetical protein K03873 ELOB; elongin-B
E TRIADDRAFT_58942 hypothetical protein K15076 ELOA; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E TRIADDRAFT_56718 hypothetical protein K08735 MSH2; DNA mismatch repair protein MSH2
E TRIADDRAFT_33687 hypothetical protein K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E TRIADDRAFT_50100 hypothetical protein K08734 MLH1; DNA mismatch repair protein MLH1
E TRIADDRAFT_21244 hypothetical protein K10858 PMS2; DNA mismatch repair protein PMS2
E TRIADDRAFT_59762 hypothetical protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E TRIADDRAFT_18979 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E TRIADDRAFT_52972 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
E TRIADDRAFT_52194 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E TRIADDRAFT_50671 hypothetical protein K07466 RFA1; replication factor A1
E TRIADDRAFT_32825 hypothetical protein K10739 RFA2; replication factor A2
D RFC (replication factor C)
E TRIADDRAFT_27705 hypothetical protein K10754 RFC1; replication factor C subunit 1
E TRIADDRAFT_50137 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E TRIADDRAFT_28707 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E TRIADDRAFT_26016 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E TRIADDRAFT_50695 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E TRIADDRAFT_26121 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E TRIADDRAFT_34086 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E TRIADDRAFT_24372 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E TRIADDRAFT_55562 hypothetical protein K10867 NBN; nibrin
D BRCA1-core complex
E TRIADDRAFT_54061 hypothetical protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D BRCA1-A complex
E TRIADDRAFT_54061 hypothetical protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E TRIADDRAFT_58498 hypothetical protein K20774 FAM175A; BRCA1-A complex subunit Abraxas
E TRIADDRAFT_52680 hypothetical protein K12173 BRE; BRCA1-A complex subunit BRE
D BRCA1-B complex
E TRIADDRAFT_54061 hypothetical protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E TRIADDRAFT_30066 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E TRIADDRAFT_53583 hypothetical protein K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E TRIADDRAFT_54061 hypothetical protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E TRIADDRAFT_58980 hypothetical protein K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
E TRIADDRAFT_24372 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E TRIADDRAFT_55562 hypothetical protein K10867 NBN; nibrin
D BRCA complex
E TRIADDRAFT_54061 hypothetical protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D RecA family proteins
E TRIADDRAFT_55187 hypothetical protein K10879 XRCC2; DNA-repair protein XRCC2
D Rad52 family proteins
E TRIADDRAFT_58188 hypothetical protein K10874 RDM1; RAD52 motif-containing protein 1
D Rad54 family proteins
E TRIADDRAFT_55311 hypothetical protein K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E TRIADDRAFT_55310 hypothetical protein K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E TRIADDRAFT_27976 hypothetical protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E TRIADDRAFT_19930 hypothetical protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E TRIADDRAFT_56013 hypothetical protein K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E TRIADDRAFT_11173 hypothetical protein K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E TRIADDRAFT_22834 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E TRIADDRAFT_49643 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E TRIADDRAFT_56278 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
E TRIADDRAFT_57881 hypothetical protein K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E TRIADDRAFT_50671 hypothetical protein K07466 RFA1; replication factor A1
E TRIADDRAFT_32825 hypothetical protein K10739 RFA2; replication factor A2
D Protein phosphatase 4
E TRIADDRAFT_64151 protein phsophatase-2a K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E TRIADDRAFT_55822 hypothetical protein K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E TRIADDRAFT_55408 hypothetical protein K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E TRIADDRAFT_50359 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E TRIADDRAFT_51742 hypothetical protein K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E TRIADDRAFT_58776 hypothetical protein K19022 AP5B1; AP-5 complex subunit beta-1
E TRIADDRAFT_62867 hypothetical protein K19023 AP5M1; AP-5 complex subunit mu-1
E TRIADDRAFT_62031 hypothetical protein K19023 AP5M1; AP-5 complex subunit mu-1
E TRIADDRAFT_61078 hypothetical protein K19024 AP5S1; AP-5 complex subunit sigma-1
E TRIADDRAFT_52911 hypothetical protein K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E TRIADDRAFT_60486 hypothetical protein K22803 SMC5; structural maintenance of chromosomes protein 5
E TRIADDRAFT_60489 hypothetical protein K22803 SMC5; structural maintenance of chromosomes protein 5
E TRIADDRAFT_61013 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E TRIADDRAFT_61011 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E TRIADDRAFT_31729 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E TRIADDRAFT_57981 hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E TRIADDRAFT_60175 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E TRIADDRAFT_58431 hypothetical protein K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E TRIADDRAFT_61430 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E TRIADDRAFT_51497 hypothetical protein K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
D Other HR factors
E TRIADDRAFT_53971 hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E TRIADDRAFT_61244 hypothetical protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E TRIADDRAFT_53400 hypothetical protein K10991 SWI5; DNA repair protein Swi5/Sae3
E TRIADDRAFT_54614 hypothetical protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E TRIADDRAFT_54370 hypothetical protein K19026 SPG11; spatacsin
E TRIADDRAFT_52065 hypothetical protein K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E TRIADDRAFT_61403 hypothetical protein K20778 RAD51AP1; RAD51-associated protein 1
E TRIADDRAFT_60384 hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E TRIADDRAFT_18236 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E TRIADDRAFT_31346 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E TRIADDRAFT_55831 hypothetical protein K22806 SPIDR; DNA repair-scaffolding protein
E TRIADDRAFT_52997 hypothetical protein K23112 BRAT1; BRCA1-associated ATM activator 1
E TRIADDRAFT_52163 hypothetical protein K23456 CFAP410; cilla- and flagella-associated protein
E TRIADDRAFT_54317 hypothetical protein K25771 SWSAP1; ATPase SWSAP1
E TRIADDRAFT_55117 hypothetical protein K25791 HSF2BP; heat shock factor 2-binding protein
E TRIADDRAFT_56960 hypothetical protein K26125 MMS22L; protein MMS22-like
E TRIADDRAFT_55679 hypothetical protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E TRIADDRAFT_61626 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E TRIADDRAFT_61074 hypothetical protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E TRIADDRAFT_20924 hypothetical protein K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E TRIADDRAFT_24372 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E TRIADDRAFT_50031 hypothetical protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E TRIADDRAFT_52000 hypothetical protein K10886 XRCC4; DNA-repair protein XRCC4
E TRIADDRAFT_53808 hypothetical protein K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E TRIADDRAFT_28268 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E TRIADDRAFT_60774 hypothetical protein K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E TRIADDRAFT_50243 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E TRIADDRAFT_18245 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E TRIADDRAFT_61257 hypothetical protein K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E TRIADDRAFT_53902 hypothetical protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E TRIADDRAFT_54573 hypothetical protein K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E TRIADDRAFT_20728 hypothetical protein K25792 JMJD8; jumonji domain-containing protein 8
E TRIADDRAFT_54129 hypothetical protein K26129 SHLD2; shieldin complex subunit 2
E TRIADDRAFT_57743 hypothetical protein K26130 SHLD3; shieldin complex subunit 3
C FA (Fanconi anemia) pathway
D FA core complex
E TRIADDRAFT_55509 hypothetical protein K10888 FANCA; fanconi anemia group A protein
E TRIADDRAFT_60008 hypothetical protein K10889 FANCB; fanconi anemia group B protein
E TRIADDRAFT_52119 hypothetical protein K10892 FANCE; fanconi anemia group E protein
E TRIADDRAFT_56719 hypothetical protein K10893 FANCF; fanconi anemia group F protein
E TRIADDRAFT_59799 hypothetical protein K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E TRIADDRAFT_55800 hypothetical protein K10898 FAAP24; fanconi anemia-associated protein
D FA core complex binding factors
E TRIADDRAFT_57355 hypothetical protein K06054 HES1; hairy and enhancer of split 1
E TRIADDRAFT_57398 hypothetical protein K11511 APITD1; centromere protein S
E TRIADDRAFT_30629 hypothetical protein K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E TRIADDRAFT_22834 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E TRIADDRAFT_49643 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E TRIADDRAFT_56278 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
E TRIADDRAFT_57881 hypothetical protein K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
E TRIADDRAFT_61761 hypothetical protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E TRIADDRAFT_54061 hypothetical protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E TRIADDRAFT_30066 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E TRIADDRAFT_54130 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E TRIADDRAFT_53547 hypothetical protein K11137 TELO2; telomere length regulation protein
E TRIADDRAFT_22317 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E TRIADDRAFT_38140 expressed hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E TRIADDRAFT_23113 hypothetical protein K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
D Ubiquitin ligases
E TRIADDRAFT_56425 hypothetical protein K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E TRIADDRAFT_60247 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E TRIADDRAFT_57645 hypothetical protein K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D TRIADDRAFT_2325 hypothetical protein K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D TRIADDRAFT_22932 hypothetical protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D TRIADDRAFT_53871 hypothetical protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D TRIADDRAFT_34116 hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D TRIADDRAFT_34128 hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D TRIADDRAFT_34124 hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D TRIADDRAFT_34129 hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D TRIADDRAFT_25115 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D TRIADDRAFT_63282 expressed hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D TRIADDRAFT_37524 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D TRIADDRAFT_50695 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
D TRIADDRAFT_30208 hypothetical protein K24051 SPRTN; SprT-like domain-contaning protein Spartan
D TRIADDRAFT_56122 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D TRIADDRAFT_61311 hypothetical protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D TRIADDRAFT_53881 hypothetical protein K10903 HUS1; HUS1 checkpoint protein
D TRIADDRAFT_19202 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D TRIADDRAFT_18196 hypothetical protein K06662 HRAD17; cell cycle checkpoint protein
D TRIADDRAFT_50137 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D TRIADDRAFT_28707 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D TRIADDRAFT_26016 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D TRIADDRAFT_19202 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D TRIADDRAFT_53559 hypothetical protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D TRIADDRAFT_51712 hypothetical protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D TRIADDRAFT_53547 hypothetical protein K11137 TELO2; telomere length regulation protein
D TRIADDRAFT_51768 hypothetical protein K20403 TTI1; TELO2-interacting protein 1
D TRIADDRAFT_55162 hypothetical protein K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D TRIADDRAFT_53676 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D TRIADDRAFT_54713 hypothetical protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D TRIADDRAFT_54712 hypothetical protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D TRIADDRAFT_33879 hypothetical protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D TRIADDRAFT_24287 hypothetical protein K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D TRIADDRAFT_29114 hypothetical protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D TRIADDRAFT_58617 hypothetical protein K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D TRIADDRAFT_63361 expressed hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D TRIADDRAFT_63383 expressed hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D TRIADDRAFT_30248 hypothetical protein K20780 MDC1; mediator of DNA damage checkpoint protein 1
D TRIADDRAFT_5070 hypothetical protein K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D TRIADDRAFT_25143 hypothetical protein K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D TRIADDRAFT_30735 hypothetical protein K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
D TRIADDRAFT_56951 hypothetical protein K22422 DONSON; protein downstream neighbor of Son
D TRIADDRAFT_58901 hypothetical protein K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D TRIADDRAFT_63201 expressed hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D TRIADDRAFT_57035 hypothetical protein K24778 ZFYVE19; abscission/NoCut checkpoint regulator
B Other factors with a suspected DNA repair function
C DNA polymerases
D TRIADDRAFT_25163 hypothetical protein K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D TRIADDRAFT_54659 hypothetical protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D TRIADDRAFT_31281 hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D TRIADDRAFT_21698 hypothetical protein K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D TRIADDRAFT_53685 hypothetical protein K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D TRIADDRAFT_2710 hypothetical protein K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D TRIADDRAFT_11949 hypothetical protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D TRIADDRAFT_64168 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D TRIADDRAFT_37778 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D TRIADDRAFT_50080 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D TRIADDRAFT_26014 hypothetical protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D TRIADDRAFT_22923 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D TRIADDRAFT_21035 hypothetical protein K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D TRIADDRAFT_54258 hypothetical protein K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D TRIADDRAFT_24211 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D TRIADDRAFT_50804 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D TRIADDRAFT_55441 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E TRIADDRAFT_58651 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TRIADDRAFT_30689 hypothetical protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E TRIADDRAFT_4611 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E TRIADDRAFT_21050 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D TRIADDRAFT_22923 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D TRIADDRAFT_24211 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024