+D Receptor KO
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G Protein-Coupled Receptors - Trichoplax adhaerens (placozoan)
%
!
ARhodopsin family
B Biogenic amine
C Acetylcholine (muscarinic)
C Adrenaline
D TRIADDRAFT_59536 hypothetical protein K04135 ADRA1A; adrenergic receptor alpha-1A
D TRIADDRAFT_59551 hypothetical protein K04136 ADRA1B; adrenergic receptor alpha-1B
C Dopamine
D TRIADDRAFT_58713 hypothetical protein K04144 DRD1; dopamine receptor D1
D TRIADDRAFT_59248 hypothetical protein K04144 DRD1; dopamine receptor D1
C Dopamine and ecdysteroid
C Histamine
D TRIADDRAFT_58722 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_15459 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_58847 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_29004 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_4509 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_51667 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_51384 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_4188 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_55912 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_55852 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_52932 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_54003 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_56568 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_14615 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_54417 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_54537 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_61508 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_60063 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_60580 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_60579 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_61025 hypothetical protein K04150 HRH2; histamine receptor H2
D TRIADDRAFT_31670 hypothetical protein K04150 HRH2; histamine receptor H2
C Octopamine and tryamine
C Serotonin
D TRIADDRAFT_29696 hypothetical protein K04160 HTR4; 5-hydroxytryptamine receptor 4
D TRIADDRAFT_33970 hypothetical protein K04160 HTR4; 5-hydroxytryptamine receptor 4
D TRIADDRAFT_55896 hypothetical protein K04160 HTR4; 5-hydroxytryptamine receptor 4
C Trace amine
D TRIADDRAFT_5190 hypothetical protein K05051 TAAR; trace amine associated receptor
D TRIADDRAFT_58725 hypothetical protein K05051 TAAR; trace amine associated receptor
D TRIADDRAFT_59425 hypothetical protein K05051 TAAR; trace amine associated receptor
D TRIADDRAFT_29642 hypothetical protein K05051 TAAR; trace amine associated receptor
D TRIADDRAFT_58724 hypothetical protein K05051 TAAR; trace amine associated receptor
D TRIADDRAFT_56106 hypothetical protein K05051 TAAR; trace amine associated receptor
D TRIADDRAFT_62528 hypothetical protein K05051 TAAR; trace amine associated receptor
B Peptide
C Adrenomedullin (G10D)
C Adropin
C Apelin
C Anaphylatoxin
C Angiotensin
C BigLEN
C Bombesin
C Bradykinin
C Cholecystokinin
D TRIADDRAFT_59678 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
C Endothelin
C fMet-Leu-Phe
C Follicle stimulating hormone (FSH)
C Galanin
D TRIADDRAFT_57363 hypothetical protein K04230 GALR1; galanin receptor 1
D TRIADDRAFT_18468 hypothetical protein K04230 GALR1; galanin receptor 1
D TRIADDRAFT_62237 hypothetical protein K04230 GALR1; galanin receptor 1
D TRIADDRAFT_62238 hypothetical protein K04230 GALR1; galanin receptor 1
D TRIADDRAFT_51669 hypothetical protein K04233 ASTA-R; allatostatin A receptor
D TRIADDRAFT_33371 hypothetical protein K04233 ASTA-R; allatostatin A receptor
D TRIADDRAFT_3740 hypothetical protein K04233 ASTA-R; allatostatin A receptor
D TRIADDRAFT_15639 hypothetical protein K04233 ASTA-R; allatostatin A receptor
C Ghrelin
C Gonadotropin-releasing hormone (GnRH)
C Lutropin-choriogonadotropic hormone
C Melanin-concentrating hormone (MCH)
C Melanocortin
C Motilin
C Neuromedin U
D TRIADDRAFT_56808 hypothetical protein K05053 NMUR2; neuromedin U receptor 2
C Neuropeptide FF
D TRIADDRAFT_15905 hypothetical protein K04240 NPFFR1; neuropeptide FF receptor 1
D TRIADDRAFT_4556 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_51389 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_55595 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_15366 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_56077 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_15472 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_57366 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_23455 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_23413 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_57365 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_61884 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_61975 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_62094 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D TRIADDRAFT_62095 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
C Neuropeptide S
C Neuropeptide W / neuropeptide B
C Neuropeptide Y
D TRIADDRAFT_5049 hypothetical protein K04204 NPY1R; neuropeptide Y receptor type 1
D TRIADDRAFT_59454 hypothetical protein K04204 NPY1R; neuropeptide Y receptor type 1
C Neurotensin
C Opioid
D TRIADDRAFT_58778 hypothetical protein K04214 OPRK1; kappa-type opioid receptor
D TRIADDRAFT_3799 hypothetical protein K04214 OPRK1; kappa-type opioid receptor
D TRIADDRAFT_53370 hypothetical protein K04214 OPRK1; kappa-type opioid receptor
C Orexigenic neuropeptide QRFP
C Orexin
C Oxytocin
C Prokineticin
D TRIADDRAFT_56053 hypothetical protein K08379 PROKR1; prokineticin receptor 1
C Prolactin-releasing peptide (PrRP)
D TRIADDRAFT_56624 hypothetical protein K04314 PRLHR; prolactin releasing hormone receptor
D TRIADDRAFT_62627 hypothetical protein K04314 PRLHR; prolactin releasing hormone receptor
C Prosaposin
C Relaxin
D TRIADDRAFT_24941 hypothetical protein K04307 RXFP2; relaxin family peptide receptor 2
D TRIADDRAFT_61684 hypothetical protein K04307 RXFP2; relaxin family peptide receptor 2
D TRIADDRAFT_62195 hypothetical protein K04307 RXFP2; relaxin family peptide receptor 2
C Somatostatin
D TRIADDRAFT_29133 hypothetical protein K04217 SSTR1; somatostatin receptor 1
D TRIADDRAFT_59520 hypothetical protein K04218 SSTR2; somatostatin receptor 2
D TRIADDRAFT_58689 hypothetical protein K04219 SSTR3; somatostatin receptor 3
D TRIADDRAFT_56127 hypothetical protein K04221 SSTR5; somatostatin receptor 5
C Tachykinin
D TRIADDRAFT_54513 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_59342 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_14401 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_51521 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_56070 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_24297 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_59455 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_56177 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_16798 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_62156 hypothetical protein K04223 TACR2; tachykinin receptor 2
D TRIADDRAFT_36385 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_58993 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_58844 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_59369 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_59370 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_51878 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_51879 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_52809 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_60081 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_60706 hypothetical protein K04224 TACR3; tachykinin receptor 3
D TRIADDRAFT_56543 hypothetical protein K14071 LKR; leucokinin receptor
C Thrombin
C Thyrotropin
D TRIADDRAFT_12963 hypothetical protein K04249 TSHR; thyrotropin receptor
C Thyrotropin-releasing hormone (TRH)
C Urotensin II
C Vasopressin
C Neuropeptide receptors
B Chemokine
C CC Chemokine
C CXC Chemokine
C CX3C Chemokine
C C Chemokine
C Chemokine like
B Base and nucleoside
C Purine / pyrimidine
C Adenosine
D TRIADDRAFT_59538 hypothetical protein K04268 ADORA3; adenosine receptor A3
B Lipid
C Arachidonylglycine
C Bile acid
C Cysteinyl leukotriene
C Free fatty acid
C HETE and oxoETE
C Leukotriene
C Lysophosphatidic acid
C Lysophosphatidylinositol
C Lysophosphatidylserine
C Oleoylethanolamide
C Prostaglandin
D TRIADDRAFT_58786 hypothetical protein K04261 PTGER4; prostaglandin E receptor 4
C Prostacyclin
C Sphingolipid
C Thromboxane
B Vision
C Opsin
D TRIADDRAFT_58557 hypothetical protein K04250 RHO; rhodopsin
D TRIADDRAFT_58576 hypothetical protein K04255 OPN4; r-opsin
D TRIADDRAFT_59637 hypothetical protein K04255 OPN4; r-opsin
D TRIADDRAFT_5735 hypothetical protein K04255 OPN4; r-opsin
B Others
C Alpha-ketoglutarate
C Cannabinoid
C Estrogen
C Hydroxy-carboxylic acid
C L-Tryptophan and L-Phenylalanine
C Mas proto-oncogene and Mas-related (MRGs)
C Melatonin
D TRIADDRAFT_58712 hypothetical protein K04285 MTNR1A; melatonin receptor type 1A
D TRIADDRAFT_19440 hypothetical protein K04285 MTNR1A; melatonin receptor type 1A
D TRIADDRAFT_58699 hypothetical protein K04286 MTNR1B; melatonin receptor type 1B
D TRIADDRAFT_61553 hypothetical protein K04286 MTNR1B; melatonin receptor type 1B
C Oxysterol
C Platelet activating factor
C Proton-sensing GPCRs
C R-spondin
C Super conserved receptor expressed in brain (SREB)
C Trissin
C Orphan GPCRs / unclassified GPCRs
#
ASecretin receptor family
B Calcium-regulating peptide
C Calcitonin
C Parathyroid hormone
B Hypothalamic hormone
C Corticotropin-releasing hormone (CRH)
C Growth hormone-releasing hormone (GHRH)
B Pancreatic peptide
C Glucagon
B Gut peptide
C Gastric inhibitory peptide (GIP)
C Vasoactive intestinal polypeptide (VIP) and pituitary adenyl cyclase-activating peptide (PACAP)
C Secretin
B Others
C Receptor activity modifying protein
C Methuselah-like proteins (MTH)
C Pigment dispersing factor (PDF)
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AAdhesion receptor family
B Cadherin EGF LAG (CELSR)
B EGF-like module-containing mucin-like hormone receptor-like (EMR)
C TRIADDRAFT_60092 hypothetical protein K08445 ADGRE4; adhesion G protein-coupled receptor E4
B Latrophilin
B Brain-specific angiogenesis inhibitor (BAI)
B Others
C TRIADDRAFT_60710 hypothetical protein K08462 ADGRA3; adhesion G protein-coupled receptor A3
C TRIADDRAFT_57362 hypothetical protein K08465 ADGRD1; adhesion G-protein coupled receptor D1
C TRIADDRAFT_55994 hypothetical protein K08465 ADGRD1; adhesion G-protein coupled receptor D1
C TRIADDRAFT_55995 hypothetical protein K08465 ADGRD1; adhesion G-protein coupled receptor D1
C TRIADDRAFT_61850 hypothetical protein K08465 ADGRD1; adhesion G-protein coupled receptor D1
C TRIADDRAFT_61852 hypothetical protein K08465 ADGRD1; adhesion G-protein coupled receptor D1
#
AMetabotropic glutamate receptor family
B Glutamate (metabotropic)
C TRIADDRAFT_54290 hypothetical protein K04603 GRM1; metabotropic glutamate receptor 1
C TRIADDRAFT_59560 hypothetical protein K04603 GRM1; metabotropic glutamate receptor 1
C TRIADDRAFT_59554 hypothetical protein K04606 GRM3; metabotropic glutamate receptor 3
C TRIADDRAFT_15193 hypothetical protein K04606 GRM3; metabotropic glutamate receptor 3
C TRIADDRAFT_19351 hypothetical protein K04606 GRM3; metabotropic glutamate receptor 3
C TRIADDRAFT_29698 hypothetical protein K04610 GRM8; metabotropic glutamate receptor 8
B GABA
C TRIADDRAFT_52983 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_58979 expressed hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_58938 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_58939 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_59024 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_59025 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_28568 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_28937 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51773 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_18816 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51324 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51325 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51330 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51333 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51358 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_20304 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51774 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51775 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_61926 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_52577 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_52578 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_52579 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_52582 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_55426 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_55428 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_64091 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_24350 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_54955 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_52580 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_51953 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_52576 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_57193 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_56610 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_56611 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_60055 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_26726 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_54957 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_55385 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_55425 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_55500 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_60050 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_30267 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C TRIADDRAFT_30374 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
B Calcium-sensing
C TRIADDRAFT_59571 hypothetical protein K04612 CASR; calcium-sensing receptor
C TRIADDRAFT_29555 hypothetical protein K04612 CASR; calcium-sensing receptor
C TRIADDRAFT_11320 hypothetical protein K04612 CASR; calcium-sensing receptor
C TRIADDRAFT_11108 hypothetical protein K04612 CASR; calcium-sensing receptor
C TRIADDRAFT_10902 hypothetical protein K04612 CASR; calcium-sensing receptor
B Orphan GPRC5
B Unclassified GPCRs
#
AFrizzled / Smoothened family
B TRIADDRAFT_31674 hypothetical protein K02842 FZD9_10; frizzled 9/10
#
AOthers
B Chemoreception
C Olfactory
D TRIADDRAFT_58809 hypothetical protein K04257 OLFR; olfactory receptor
C Taste
C Vomeronasal pheromone
D TRIADDRAFT_59557 hypothetical protein K04613 V2R; vomeronasal 2 receptor
D TRIADDRAFT_14966 hypothetical protein K04613 V2R; vomeronasal 2 receptor
D TRIADDRAFT_29583 hypothetical protein K04613 V2R; vomeronasal 2 receptor
D TRIADDRAFT_25328 hypothetical protein K04613 V2R; vomeronasal 2 receptor
C Insect odorant and taste
D TRIADDRAFT_54202 hypothetical protein K08471 GR; gustatory receptor
D TRIADDRAFT_61241 hypothetical protein K08471 GR; gustatory receptor
C Nematode chemoreception
C Fungal mating pheromone
B Others
C Ocular albinism proteins
D TRIADDRAFT_59750 hypothetical protein K08470 OA1; ocular albinism type 1 protein
C Neuronostatin
D TRIADDRAFT_20602 hypothetical protein K22985 GPR107; G protein-coupled receptor 107
C Plant Mlo receptors
C cAMP signaling
D TRIADDRAFT_59516 hypothetical protein K22987 GCR1; cAMP receptor-like G-protein coupled receptor
C Bacterial rhodopsin
C Orphan GPCRs
D TRIADDRAFT_55435 hypothetical protein K22988 TPRA1; transmembrane protein adipocyte-associated 1
D TRIADDRAFT_52736 hypothetical protein K22989 GPR137; integral membrane protein GPR137
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 8, 2022
#
Classification taken and modified from GPCRDB