+F Repair protein KO
#
DNA Repair and Recombination Proteins - Theileria annulata
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D TA20175 DEAD-box helicase, putative K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
C BER (base exicision repair)
D DNA glycosylases
E TA12830 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TA16100 7,8 dihydro-8-oxoguanine DNA glycosylase, putative K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E TA05440 endonuclease III, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E TA12590 apurinic/apyrimidinic endonuclease Apn1-like, putative K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F TA06290 DNA polymerase delta catalytic subunit (Pold1 homologue), putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F TA13340 DNA polymerase delta small subunit, putative K02328 POLD2; DNA polymerase delta subunit 2
E DNA polymerase epsilon complex
F TA09840 DNA polymerase epsilon (catalytic subunit), putative K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F TA12280 hypothetical protein, conserved K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F TA12275 SfiI-subtelomeric fragment related protein family member, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F TA12265 SfiI-subtelomeric fragment related protein family member, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
E TA14075 proliferating cell nuclear antigen 2 (PCNA2), putative K04802 PCNA; proliferating cell nuclear antigen
E TA04590 proliferating cell nuclear antigen (PCNA) 1, putative K04802 PCNA; proliferating cell nuclear antigen
E TA15785 5'-3' exonuclease, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E TA05175 DNA ligase 1 (precursor), putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E TA20015 polynucleotide kinase 3'-phosphatase-like protein, putative K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F TA05020 hypothetical protein, conserved K10838 XPC; xeroderma pigmentosum group C-complementing protein
F TA06130 DNA repair protein (RAD23 homologue), putative K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F TA10565 hypothetical protein, conserved K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F TA19595 damage-specific DNA binding protein 1, putative K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F TA03235 DNA-directed RNA polymerase II largest subunit, putative K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F TA07925 DNA-directed RNA polymerase II subunit, putative K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F TA19735 DNA-directed RNA polymerase ii, putative K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F TA12735 RNA polymerase 16kd subunit, RPB4-like, putative K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F TA10195 DNA-directed RNA polymerase, subunit (RPB5 homologue), putative K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F TA08570 RNA polymerase common subunit (Rpb6 homologue), putative K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F TA19500 DNA-directed RNA polymerase ii, putative K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F TA19535 DNA-directed RNA polymerases i, ii, and iii 17.1 kDa polypeptide, putative K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F TA11880 DNA-directed RNA polymerase 2 subunit, putative K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F TA02635 DNA-directed RNA polymerase II, putative K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F TA10565 hypothetical protein, conserved K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F TA19595 damage-specific DNA binding protein 1, putative K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F TA17205 DNA repair helicase, putative K10841 ERCC6; DNA excision repair protein ERCC-6
F TA05165 hypothetical protein, conserved K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E TA11585 DNA repair helicase, putative K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E TA19155 rad3-like DNA helicase-related, putative K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E TA04780 hypothetical protein, conserved K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E TA11370 hypothetical protein, conserved K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E TA16710 TFIIH subunit, Tf2b homologue, putative K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E TA04975 hypothetical protein, conserved K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E TA07000 cyclin-dependent kinase CRK3 (CDK7 homologue), putative K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E TA11045 cyclin, putative K06634 CCNH; cyclin H
E TA13640 CDK-activating kinase assembly factor, putative K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E TA15495 replication factor-a protein 1, putative K07466 RFA1; replication factor A1
E TA11650 hypothetical protein K10739 RFA2; replication factor A2
D Other NER factors
E TA16745 DNA repair protein (RAD10 homologue), putative K10849 ERCC1; DNA excision repair protein ERCC-1
E TA04325 DNA repair (RAD6) endonuclease, putative K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E TA08900 endonuclease (xp-g/RAD2 homologue), putative K10846 ERCC5; DNA excision repair protein ERCC-5
E TA05175 DNA ligase 1 (precursor), putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E TA06585 hypothetical protein, conserved K15075 MET18; DNA repair/transcription protein MET18/MMS19
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E TA20735 DNA mismatch repair protein msh2, putative K08735 MSH2; DNA mismatch repair protein MSH2
E TA19305 DNA mismatch repair protein, MutS family, putative K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E TA06860 DNA mismatch repair (MLH1 homologue), putative K08734 MLH1; DNA mismatch repair protein MLH1
E TA04865 DNA mismatch repair protein, putative K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E TA06290 DNA polymerase delta catalytic subunit (Pold1 homologue), putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E TA13340 DNA polymerase delta small subunit, putative K02328 POLD2; DNA polymerase delta subunit 2
D RPA (replication factor A)
E TA15495 replication factor-a protein 1, putative K07466 RFA1; replication factor A1
E TA11650 hypothetical protein K10739 RFA2; replication factor A2
D RFC (replication factor C)
E TA18630 replication factor c-related protein, putative K10754 RFC1; replication factor C subunit 1
E TA16350 replication factor C subunit (RPC2 homologue), putative K10755 RFC2_4; replication factor C subunit 2/4
E TA04525 replication factor, putative K10755 RFC2_4; replication factor C subunit 2/4
E TA08130 replication factor C subunit, putative K10756 RFC3_5; replication factor C subunit 3/5
E TA17080 replication factor C subunit, putative K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E TA14075 proliferating cell nuclear antigen 2 (PCNA2), putative K04802 PCNA; proliferating cell nuclear antigen
E TA04590 proliferating cell nuclear antigen (PCNA) 1, putative K04802 PCNA; proliferating cell nuclear antigen
E TA09295 exonuclease 1, putative K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E TA05175 DNA ligase 1 (precursor), putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E TA10845 double-strand break repair protein, putative K10865 MRE11; double-strand break repair protein MRE11
E TA11630 DNA repair protein rad50, putative K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E TA10845 double-strand break repair protein, putative K10865 MRE11; double-strand break repair protein MRE11
E TA11630 DNA repair protein rad50, putative K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E TA07350 DNA repair (Rad51 homologue) protein, putative K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E TA07350 DNA repair (Rad51 homologue) protein, putative K04482 RAD51; DNA repair protein RAD51
D Rad52 family proteins
D Rad54 family proteins
E TA05745 recombinational repair (RAD54 homologue) protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
E TA13565 DNA helicase (SGS1 homologue), putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E TA13565 DNA helicase (SGS1 homologue), putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E TA17755 DNA topoisomerase iii, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E TA15495 replication factor-a protein 1, putative K07466 RFA1; replication factor A1
E TA11650 hypothetical protein K10739 RFA2; replication factor A2
D Protein phosphatase 4
E TA12805 serine/threonine protein phosphatase pp-x isozyme 1, putative K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E TA14035 hypothetical protein K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E TA18585 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E TA08750 chromosome maintenance protein (SMC5 homologue), putative K22803 SMC5; structural maintenance of chromosomes protein 5
E TA18975 SMC-like protein, putative K22804 SMC6; structural maintenance of chromosomes protein 6
E TA20410 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
D Other HR factors
E TA04250 hypothetical protein, conserved K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E TA07700 hypothetical protein, conserved K10881 SHFM1; 26 proteasome complex subunit DSS1
E TA15825 26S protease subunit, putative K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E TA02880 minichromosome maintenance (MCM), putative K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
E TA08800 DNA replication protein (MCM homologue), putative K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
E TA10845 double-strand break repair protein, putative K10865 MRE11; double-strand break repair protein MRE11
E TA11630 DNA repair protein rad50, putative K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
E TA13565 DNA helicase (SGS1 homologue), putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E TA17755 DNA topoisomerase iii, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E TA07350 DNA repair (Rad51 homologue) protein, putative K04482 RAD51; DNA repair protein RAD51
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E TA03685 hypothetical protein, conserved K23314 WRAP53; telomerase Cajal body protein 1
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D TA15860 hypothetical protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D TA03980 ubiquitin-conjugating enzyme E2, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D TA12340 ubiquitin-conjugating enzyme E2, putative K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D TA02645 ubiquitin-conjugating enzyme (MMS homologue), putative K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D TA20510 ubiquitin-conjugating enzyme e2, putative K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D TA14075 proliferating cell nuclear antigen 2 (PCNA2), putative K04802 PCNA; proliferating cell nuclear antigen
D TA04590 proliferating cell nuclear antigen (PCNA) 1, putative K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
D TA16350 replication factor C subunit (RPC2 homologue), putative K10755 RFC2_4; replication factor C subunit 2/4
D TA04525 replication factor, putative K10755 RFC2_4; replication factor C subunit 2/4
D TA08130 replication factor C subunit, putative K10756 RFC3_5; replication factor C subunit 3/5
D TA17080 replication factor C subunit, putative K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
D TA05225 hypothetical protein, conserved K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D TA14115 14-3-3 protein homologue, putative K06630 YWHAE; 14-3-3 protein epsilon
D TA04080 AAA family ATPase, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D TA19785 hypothetical protein, conserved K17815 EXO5; exonuclease V [EC:3.1.-.-]
C Helicases
C PSO4 complex
D TA03395 hypothetical protein, conserved K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D TA17065 Myb-like DNA binding protein (CDC5 homologue), putative K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D TA14630 hypothetical protein, conserved K12861 BCAS2; pre-mRNA-splicing factor SPF27
D TA10595 hypothetical protein, conserved K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D TA20975 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D TA05060 ribonucleoside-diphosphate reductase large chain, putative K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D TA06715 ribonucleotide reductase R2 subunit or ribonucleoside-diphosphate reductase small chain, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D TA09665 ribonucleoside reductase, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E TA12830 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TA05440 endonuclease III, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F TA18990 DNA-directed RNA polymerase alpha chain, putative K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F TA03310 DNA-directed RNA polymerase D subunit, putative K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F TA14985 topoisomerase IV subunit A, putative K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F TA16475 DNA topoisomerase II, putative K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
F TA08755 DNA helicase (SGS1 homologue), putative K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D TA20975 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024