+F Repair protein KO
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DNA Repair and Recombination Proteins - Taylorella asinigenitalis 14/45
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E KUM_0783 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E KUM_0549 putative endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D KUM_1358 putative NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KUM_0274 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E KUM_0783 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E KUM_0535 putative uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E KUM_0306 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E KUM_0549 putative endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E KUM_1212 putative endonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E KUM_0055 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E KUM_0865 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E KUM_0539 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E KUM_0304 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E KUM_1072 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E KUM_0161 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E KUM_0044 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E KUM_0009 uvrC; excinuclease ABC, subunit C K03703 uvrC; excinuclease ABC subunit C
E KUM_0266 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KUM_0916 Putative helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KUM_0304 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E KUM_0539 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F KUM_1164 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F KUM_1163 rpoC; DNA-directed RNA polymerase subunit beta K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F KUM_0178 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F KUM_0469 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F KUM_0528 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E KUM_0387 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E KUM_0663 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E KUM_0130 exodeoxyribonuclease VII complex K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E KUM_0298 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E KUM_0975 dnaE2; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E KUM_0907 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E KUM_0577 holC; DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E KUM_0392 holA; =putative DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E KUM_0077 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E KUM_1309 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E KUM_1310 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D DNA ligase
E KUM_0539 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E KUM_0266 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KUM_0916 Putative helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KUM_1124 ssb7; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E KUM_1125 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E KUM_0833 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E KUM_0047 recA; RecA protein (recombinase A) K03553 recA; recombination protein RecA
E KUM_0641 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E KUM_0638 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E KUM_0642 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E KUM_0774 Primosomal protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E KUM_0293 priB; putative primosomal replication protein K02686 priB; primosomal replication protein N
D RecFOR pathway proteins
E KUM_0047 recA; RecA protein (recombinase A) K03553 recA; recombination protein RecA
E KUM_0478 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E KUM_0280 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E KUM_0448 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E KUM_0865 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E KUM_0575 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
E KUM_0674 recR; recombination protein RecR K06187 recR; recombination protein RecR
E KUM_0701 recN; ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
E KUM_0046 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E KUM_0641 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E KUM_0638 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E KUM_0642 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E KUM_0770 CRISPR associated helicase Cas1 family protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E KUM_1187 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F KUM_0419 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F KUM_0908 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F KUM_0145 hupB; DNA-binding protein Hu-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F KUM_0865 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F KUM_0575 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
F KUM_0674 recR; recombination protein RecR K06187 recR; recombination protein RecR
F KUM_0539 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F KUM_0644 fis; putative transcriptional regulator, Fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F KUM_0850 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F KUM_0413 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F KUM_0637 putative DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F KUM_1072 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F KUM_0161 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F KUM_0044 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D KUM_0264 UmuC family protein K03502 umuC; DNA polymerase V
D KUM_0265 putative component of DNA polymerase V K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D KUM_0047 recA; RecA protein (recombinase A) K03553 recA; recombination protein RecA
D KUM_0042 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D KUM_0701 recN; ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
D KUM_1124 ssb7; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D KUM_1125 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D KUM_0048 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D KUM_0844 helD; probable helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D KUM_0263 Helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D KUM_1358 putative NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KUM_0274 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D KUM_0017 nrdA; ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D KUM_0018 nrdB; ribonucleoside diphosphate reductase 1, beta subunit, ferritin-like protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024