+E Ubiquitin system KO
#
Ubiquitin System - Tribolium castaneum (red flour beetle)
%
!
AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 641546 Pub; polyubiquitin K08770 UBC; ubiquitin C
C 656930 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 664412 ubiquitin K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 657472 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 661681 NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 660521 uncharacterized LOC660521 K02983 RP-S30e; small subunit ribosomal protein S30e
C 659377 small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
C 661847 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 655119 autophagy-related 12-like K08336 ATG12; ubiquitin-like protein ATG12
C 103312329 ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
C 663257 uncharacterized LOC663257 K12163 ZFAND4; AN1-type zinc finger protein 4
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 657621 ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 663298 SUMO-activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 658232 SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 658164 nedd8-activating enzyme E1 catalytic subunit K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 657871 nedd8-activating enzyme E1 regulatory subunit K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 663966 adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 662103 ubiquitin-like modifier-activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 657372 ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
#
AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 659763 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 658590 ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 658996 Ubc-D1; effete K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 659808 ubiquitin-conjugating enzyme E2-24 kDa K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 659653 ubiquitin-conjugating enzyme E2 G1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 662505 crl; courtless K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 656730 ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 655113 ubiquitin-conjugating enzyme E2 J1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 662641 ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 659971 ubiquitin-conjugating enzyme E2-22 kDa K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 660484 ubiquitin-conjugating enzyme E2 L3 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 657832 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 660986 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 659924 uncharacterized LOC659924 K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 661953 ubiquitin-conjugating enzyme E2 Q2 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 661636 ubiquitin-conjugating enzyme E2Q-like protein CG4502 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 658054 ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 660133 ubiquitin-conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 659470 ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 663661 ubiquitin-conjugating enzyme E2 W K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 662712 baculoviral IAP repeat-containing protein 6 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 656284 lwr; lesswright K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 659091 NEDD8-conjugating enzyme UBE2F K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 659372 NEDD8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 655634 ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 103314258 ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 657656 ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
#
AUbiquitin ligases (E3)
B HECT type E3
C 657548 ubiquitin-protein ligase E3A K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 659339 ubiquitin-protein ligase E3B K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 656759 ubiquitin-protein ligase E3C K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 661188 hexosaminidase D K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 103314102 E3 ubiquitin-protein ligase SMURF2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 662990 E3 ubiquitin-protein ligase Su(dx) K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 658915 E3 ubiquitin-protein ligase TRIP12 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 663811 E3 ubiquitin-protein ligase Nedd-4 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 657452 HUWE1; E3 ubiquitin-protein ligase HUWE1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 662668 apoptosis-resistant E3 ubiquitin protein ligase 1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 655442 E3 ubiquitin-protein ligase hyd K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 657865 probable E3 ubiquitin-protein ligase HERC1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 656972 HERC2; E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 660213 probable E3 ubiquitin-protein ligase HERC4 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 662029 E3 ubiquitin-protein ligase HECW2 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 662402 hect E3 ubiquitin ligase K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 664353 NEDD4 family-interacting protein 1 K25839 NDFIP; NEDD4 family-interacting protein
B U-box type E3
C 654916 ubiquitin conjugation factor E4 A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 661942 ubiquitin conjugation factor E4 B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 657118 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 659876 peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 658530 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 662167 E3 ubiquitin-protein ligase RBBP6 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 100307003 Ubox5; U-box domain containing 5 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 660381 E3 ubiquitin-protein ligase Bre1 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 656167 E3 ubiquitin-protein ligase CBL K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 660139 E3 ubiquitin-protein ligase Siah1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 107399267 uncharacterized LOC107399267 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 661914 uncharacterized LOC661914 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 103312834 uncharacterized LOC103312834 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 103314123 E3 ubiquitin-protein ligase SIAH1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 664417 E3 ubiquitin-protein ligase sina-like K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 103313688 probable E3 ubiquitin-protein ligase sinah K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 100142361 E3 ubiquitin-protein ligase sina K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 107398470 E3 ubiquitin-protein ligase siah-1-like K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 103314921 uncharacterized LOC103314921 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
C Ligand of Numb proteins
D 654988 PDZ domain-containing RING finger protein 4 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 664145 E3 ubiquitin-protein ligase MARCH8 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 103314783 E3 ubiquitin-protein ligase MARCH3 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 103314395 E3 ubiquitin-protein ligase MARCH2 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 103313675 E3 ubiquitin-protein ligase MARCH8 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 663760 E3 ubiquitin-protein ligase MARCH5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 659835 E3 ubiquitin-protein ligase MARCH6 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 664204 E3 ubiquitin-protein ligase Mdm2-like K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
C NFX1 proteins
D 659177 protein shuttle craft K12236 NFX1; transcriptional repressor NF-X1
D 659509 NF-X1-type zinc finger protein NFXL1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 662980 protein pellino K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 660863 peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 655690 peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 103313393 peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 657490 E3 ubiquitin-protein ligase parkin K04556 PARK2; parkin [EC:2.3.2.31]
D 664247 ankyrin repeat and IBR domain-containing protein 1 K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 660216 protein ariadne-1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 656643 protein ariadne-1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 660009 protein ariadne-2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 100142087 E3 ubiquitin-protein ligase RNF19A K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 663619 nucleoprotein TPR K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 655400 E3 ubiquitin-protein ligase rififylin K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 656253 probable E3 ubiquitin-protein ligase RNF144A K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 103314904 hypothetical protein K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 100142249 uncharacterized LOC100142249 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 103312285 hypothetical protein K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 103312284 uncharacterized LOC103312284 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
C TRAF proteins
D 661716 Traf2; TNF-receptor-associated factor 2 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 658934 brat; brain tumor protein K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 658234 tripartite motif-containing protein 2 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 663417 E3 ubiquitin-protein ligase TRIM9 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 661701 E3 ubiquitin-protein ligase TRIM37 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 660110 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 664018 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 656122 RING finger protein nhl-1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D 662871 E3 ubiquitin-protein ligase UBR2 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 657900 UBR3; E3 ubiquitin-protein ligase UBR3 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 661572 E3 ubiquitin-protein ligase UBR4 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 662472 putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 661853 E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 663905 Tiap2; inhibitor of apoptosis 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 663941 Tiap1; inhibitor of apoptosis 1 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 662992 BRCA1-associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 660508 E3 ubiquitin-protein ligase Hakai K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 661055 uncharacterized LOC661055 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 656294 DC-STAMP domain-containing protein 1 K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 662619 protein deltex K06058 DTX; deltex [EC:2.3.2.27]
D 100141549 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 661305 E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 656422 E3 ubiquitin-protein ligase LRSAM1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 103313919 E3 ubiquitin-protein ligase LRSAM1-like K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 657391 E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 655833 Mex-3; mex-3 protein K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 663742 MIB1; E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 659647 E3 ubiquitin-protein ligase MIB2 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 656720 probable E3 ubiquitin-protein ligase makorin-1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 655721 mitochondrial ubiquitin ligase activator of NFKB 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 660160 Hiw; highwire K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 664294 E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 660865 protein neuralized K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 103312931 protein neuralized-like K15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]
D 662913 RING finger and CHY zinc finger domain-containing protein 1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 656960 roquin-1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 660034 E3 ubiquitin-protein ligase RFWD3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 659139 E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 103314631 E3 ubiquitin-protein ligase BRE1A K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 658819 E3 ubiquitin-protein ligase RNF185 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 103313396 E3 ubiquitin-protein ligase RNF8-B K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 656623 RING finger protein 10 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 658838 RING finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 657770 E3 ubiquitin-protein ligase RNF13 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 661023 E3 ubiquitin-protein ligase RNF25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 655967 RING finger protein 44 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 661626 E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 656150 E3 ubiquitin-protein ligase RNF126 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 664336 RING finger protein 121 K15698 RNF121_175; RING finger protein 121/175
D 663979 protein TRC8 homolog K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 660565 E3 ubiquitin-protein ligase rnf146 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 659409 E3 ubiquitin-protein ligase MGRN1 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 662628 E3 ubiquitin-protein ligase RNF181 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 103315164 RING finger protein 165-like K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 103314084 RING-H2 finger protein ATL20 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 103314668 E3 ubiquitin-protein ligase RNF220 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 662693 E3 ubiquitin-protein ligase RNF220 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 663502 U4/U6.U5 tri-snRNP-associated protein 1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 664053 E3 ubiquitin-protein ligase SHPRH K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 664345 POSH; E3 ubiquitin-protein ligase SH3RF1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 663272 E3 ubiquitin-protein ligase synoviolin A K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 655383 E3 ubiquitin-protein ligase TM129 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 103313725 E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 103314852 E3 ubiquitin-protein ligase TRAIP K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 659632 E3 ubiquitin-protein ligase UHRF1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 100142521 E3 ubiquitin-protein ligase UHRF2-like K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 659939 RING finger protein unkempt K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 661901 zinc finger protein 598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 659211 E3 ubiquitin-protein ligase znrf1 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 100142099 E3 ubiquitin-protein ligase RNF149-like K16285 XERICO; RING/U-box domain-containing protein [EC:2.3.2.27]
B Atypical E3
C 663921 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 664517 interferon regulatory factor 2-binding protein 2 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 103313725 E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 655426 E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 662854 E3 SUMO-protein ligase PIAS2 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 661855 E3 SUMO-protein ligase NSE2 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 103314205 probable E3 SUMO-protein ligase RNF212 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 107398328 zinc finger BED domain-containing protein 4 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 657948 E3 UFM1-protein ligase 1 homolog K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 654985 DCN1-like protein 2 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 663792 DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 657768 DCN1-like protein 4 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 660670 cullin-1 K03347 CUL1; cullin 1
D Adaptor protein
E 663380 skp1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 664308 slmb; supernumerary limbs K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 103315029 F-box/WD repeat-containing protein 4 K10262 FBXW4; F-box and WD-40 domain protein 4
E 100142053 F-box/WD repeat-containing protein 5 K10263 FBXW5; F-box and WD-40 domain protein 5
E 655954 ago; archipelago K10260 FBXW7; F-box and WD-40 domain protein 7
E 657905 S-phase kinase-associated protein 2 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 100142184 F-box/LRR-repeat protein 20 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 659871 F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 103314777 uncharacterized F-box/LRR-repeat protein C02F5.7 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 661486 F-box/LRR-repeat protein 6 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 658546 F-box/LRR-repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 659466 jmjC domain-containing histone demethylation protein 1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 663569 F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 660141 F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 663612 F-box only protein 6 K10100 FBXO6; F-box protein 6
E 103313837 uncharacterized LOC103313837 K10293 FBXO7; F-box protein 7
E 655227 F-box only protein 9 K10295 FBXO9; F-box protein 9
E 656278 F-box only protein 11 K10297 FBXO11; F-box protein 11
E 661528 LIM and calponin homology domains-containing protein 1 K06084 LMO7; F-box protein 20
E 103312391 hypothetical protein K10301 FBXO21; F-box protein 21
E 103312363 uncharacterized LOC103312363 K10302 FBXO22; F-box protein 22
E 659307 F-box only protein 25 K10305 FBXO25_32; F-box protein 25/32
E 655419 F-box only protein 28 K10306 FBXO28; F-box protein 28
E 100141691 Mcm10; F-box only protein 28 K10306 FBXO28; F-box protein 28
E 656364 F-box/LRR-repeat protein 21 K10310 FBXO33; F-box protein 33
E 656676 F-box/LRR-repeat protein 3 K10314 FBXO39; F-box protein 39
E 658962 uncharacterized LOC658962 K10314 FBXO39; F-box protein 39
E 658311 F-box only protein 42 K10317 FBXO42; F-box protein 42
E 662244 F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
C Cul2 complex
D Ring finger protein
E 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 663441 cullin-2 K03870 CUL2; cullin 2
D Adoptor protein
E 664284 transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 657699 transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
D Target recognizing subunit
E 657278 hypothetical protein K03871 VHL; von Hippel-Lindau disease tumor supressor
E 103313576 Vhl; von Hippel-Lindau disease tumor suppressor K03871 VHL; von Hippel-Lindau disease tumor supressor
E 663693 leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 100141886 protein fem-1 homolog CG6966 K25805 FEM1A_C; protein fem-1 homolog A/C
E 655478 protein fem-1 homolog CG6966 K25805 FEM1A_C; protein fem-1 homolog A/C
E 664462 protein fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 662780 amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 663040 kelch domain-containing protein 3 K25808 KLHDC3; kelch domain-containing protein 3
E 656704 kelch domain-containing protein 10 homolog K25809 KLHDC10; kelch domain-containing protein 10
E 657273 protein zyg-11 homolog K10350 ZYG11; Zyg-11 protein
E 659004 protein zer-1 homolog K10350 ZYG11; Zyg-11 protein
E 659149 zinc finger SWIM domain-containing protein 8 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 655765 cullin-3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 661961 kelch-like protein 5 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 663276 ring canal kelch homolog K10443 KLHL2_3; kelch-like protein 2/3
E 659481 kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 661075 kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 662966 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 661567 kelch-like protein 18 K10455 KLHL18; kelch-like protein 18
E 655908 kelch-like ECH-associated protein 1 K10456 KLHL19; kelch-like protein 19
E 655440 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 661118 kelch-like protein 26 K10463 KLHL26; kelch-like protein 26
E 663708 actin-binding protein IPP K13956 IPP; actin-binding protein IPP
E 103314926 uncharacterized LOC103314926 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 103313563 BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 663586 BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 659490 BTB/POZ domain-containing protein 7 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 659745 uncharacterized LOC659745 K10480 BTBD8; BTB/POZ domain-containing protein 8
E 660246 BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 657718 BTB/POZ domain-containing protein 10 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 656141 Gcl; germ cell-less K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 661758 ankyrin repeat and BTB/POZ domain-containing protein 2 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 661174 rho-related BTB domain-containing protein 2 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 655793 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 654911 BTB/POZ domain-containing protein kctd15-like K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 656203 BTB/POZ domain-containing protein KCTD5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 656111 BTB/POZ domain-containing protein KCTD3 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 662864 BTB/POZ domain-containing protein KCTD12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 654892 BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 655033 protein roadkill K10523 SPOP; speckle-type POZ protein
E 662949 speckle-type POZ protein-like B K10523 SPOP; speckle-type POZ protein
E 660292 leucine-zipper-like transcriptional regulator 1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 100141956 cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 664450 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 663472 DET1 homolog K10571 DET1; de-etiolated-1
E 103313711 DET1- and DDB1-associated protein 1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 659188 protein cereblon K11793 CRBN; cereblon
E 656602 protein mahjong K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 662401 protein lethal(2)denticleless K11790 DTL; denticleless
E 655014 DDB1- and CUL4-associated factor 5 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 658980 DDB1- and CUL4-associated factor 6 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 655983 DDB1- and CUL4-associated factor 6 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 658766 DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 656756 DDB1- and CUL4-associated factor 8 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 659428 WD and tetratricopeptide repeats protein 1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 655314 DDB1- and CUL4-associated factor 10 homolog K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 660405 DDB1- and CUL4-associated factor 11 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 662500 DDB1- and CUL4-associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 663659 DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 100141521 uncharacterized LOC100141521 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 661400 PH-interacting protein K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 662293 WD repeat-containing protein 26 K22382 WDR26; WD repeat-containing protein 26
E 656900 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
E 663304 RING-box protein 2 K10611 RBX2; RING-box protein 2
D Cullin
E 657244 cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E 664284 transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 657699 transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
D Target recognizing subunit
E 100142215 suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 662537 uncharacterized LOC662537 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 103312252 suppressor of cytokine signaling 6 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 103312654 hypothetical protein K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 664070 protein gustavus K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 663365 SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 655298 SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 658373 ras-related protein Rab-40B K07928 RAB40; Ras-related protein Rab-40
E 660693 RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 663380 skp1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 655935 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
D Cullin
E 664371 anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 658108 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 659043 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 662319 fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 664178 shattered; anaphase-promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
E 658314 cell division cycle protein 27 homolog K03350 APC3; anaphase-promoting complex subunit 3
E 659284 anaphase-promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
E 655746 anaphase-promoting complex subunit 5 K03352 APC5; anaphase-promoting complex subunit 5
E 658265 cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 663481 anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 655858 cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 663959 anaphase-promoting complex subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
E 103313943 anaphase-promoting complex subunit CDC26-like K03359 APC12; anaphase-promoting complex subunit 12
E 100142453 anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 662361 anaphase-promoting complex subunit 15 K25228 APC15; anaphase-promoting complex subunit 15
C BRCC complex
D 103314370 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 658609 BRCA1-A complex subunit BRE K12173 BRE; BRCA1-A complex subunit BRE
D 663507 Rad51; spindle A-like protein K04482 RAD51; DNA repair protein RAD51
D 662986 Rad51; spindle A-like protein K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
D 663619 nucleoprotein TPR K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 657779 protein RMD5 homolog A K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 655278 ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 658782 armadillo repeat-containing protein 8 K23336 ARMC8; armadillo repeat-containing protein 8
D 656236 macrophage erythroblast attacher K18624 MAEA; macrophage erythroblast attacher
D 658301 glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 660768 glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 656509 protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 662293 WD repeat-containing protein 26 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 661853 E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 103314430 transmembrane and ubiquitin-like domain-containing protein 2 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 659606 transmembrane and ubiquitin-like domain-containing protein 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 663297 erlin-1 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 657627 protein LMBR1L K25215 LMBR1L; protein LMBR1L
D 661853 E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 661948 CAND1; cullin-associated NEDD8-dissociated protein 1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 656099 COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 100142004 COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 103313031 COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 103313089 COMM domain-containing protein 5 K22561 COMMD5; COMM domain containing 5
D 103314117 uncharacterized LOC103314117 K22564 COMMD8; COMM domain containing 8
D 662429 COMM domain-containing protein 10 K22566 COMMD10; COMM domain containing 10
D 663250 coiled-coil domain-containing protein 22 homolog K23343 CCDC22; coiled-coil domain-containing protein 22
D 100141629 DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 103312253 glomulin K23345 GLMN; glomulin
D 656281 influenza virus NS1A-binding protein K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 103314689 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 660058 protein lingerer K26545 UBAP2; ubiquitin-associated protein 2
D 659521 intersectin-1 K26546 Dlish; SH3 domain-containing protein Dlish
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 663933 ubiquitin carboxyl-terminal hydrolase calypso K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 662635 ubiquitin carboxyl-terminal hydrolase K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 655264 ubiquitin carboxyl-terminal hydrolase K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 656089 ubiquitin carboxyl-terminal hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 663788 ubiquitin carboxyl-terminal hydrolase CYLD K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 657237 ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 656106 ubiquitin carboxyl-terminal hydrolase 2 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 655510 ubiquitin carboxyl-terminal hydrolase 5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 659987 ubiquitin carboxyl-terminal hydrolase 32 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 663824 USP7; ubiquitin carboxyl-terminal hydrolase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 661487 probable ubiquitin carboxyl-terminal hydrolase FAF-X K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 660907 ubiquitin-specific protease K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 663037 ubiquitin carboxyl-terminal hydrolase 46 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 657507 ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 655219 ubiquitin carboxyl-terminal hydrolase 16 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 660781 ubiquitin carboxyl-terminal hydrolase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 662889 ubiquitin carboxyl-terminal hydrolase nonstop K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 657131 ubiquitin carboxyl-terminal hydrolase 30 homolog K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 657586 ubiquitin carboxyl-terminal hydrolase 31 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 659997 ubiquitin carboxyl-terminal hydrolase 34 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 660706 ubiquitin carboxyl-terminal hydrolase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 661715 ubiquitin carboxyl-terminal hydrolase 36 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 656421 ubiquitin carboxyl-terminal hydrolase 47 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
C OTU
D 664549 ubiquitin thioesterase otubain-like K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 656223 OTU domain-containing protein 5-A K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 656687 OTU domain-containing protein 6B K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 663735 ubiquitin thioesterase trabid K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 655594 ataxin-3 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 659541 josephin-1 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 663602 protein FAM188A homolog K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 103314370 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 661230 histone H2A deubiquitinase MYSM1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 659985 MPN domain-containing protein CG4751 K24173 MPND; MPN domain-containing protein
D 657072 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 658263 STAM-binding protein-like K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D 655999 desumoylating isopeptidase 2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 663964 zinc finger with UFM1-specific peptidase domain protein K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 100142342 BRISC complex subunit Abro1-like K20799 FAM175B; BRISC complex subunit Abro1
D 655173 BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
D 103314370 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 658609 BRCA1-A complex subunit BRE K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 103313244 sentrin-specific protease K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 659719 hypothetical protein K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 656873 sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 662635 ubiquitin carboxyl-terminal hydrolase K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 655264 ubiquitin carboxyl-terminal hydrolase K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 664006 desumoylating isopeptidase 1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 659663 uncharacterized LOC659663 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D 657006 COP9 signalosome complex subunit 1 K12175 GPS1; COP9 signalosome complex subunit 1
D 655097 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 657940 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 659352 COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 663843 COP9 signalosome complex subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D 661522 COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 662067 COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 656634 COP9 signalosome complex subunit 7b K12180 COPS7; COP9 signalosome complex subunit 7
D 663600 COP9 signalosome complex subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024