+F Chromosome and associated proteins KO
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Chromosome and Associated Proteins - Tetrahymena thermophila
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AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
D TTHERM_01048090 SMC family, carboxy-terminal domain protein K06636 SMC1; structural maintenance of chromosome 1
C Adherin complex
C CTF18-RFC complex
D TTHERM_00483610 AAA family ATPase K11269 CTF18; chromosome transmission fidelity protein 18
D TTHERM_00974300 Ctf8 protein K11270 CTF8; chromosome transmission fidelity protein 8
D TTHERM_00245150 replication factor C subunit K10755 RFC2_4; replication factor C subunit 2/4
D TTHERM_00780750 replication factor C, activator 1 K10755 RFC2_4; replication factor C subunit 2/4
D TTHERM_00213600 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D TTHERM_00161180 replication factor C, activator 1 K10756 RFC3_5; replication factor C subunit 3/5
C Fork protection complex
D TTHERM_00046130 Yip1 domain protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
C Other sister chromatid cohesion factors
D TTHERM_00683180 DNA repair helicase (rad3) K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
D TTHERM_000420919 hypothetical protein K11274 WDHD1; chromosome transmission fidelity protein 4
D TTHERM_00670400 amine-terminal acetyltransferase complex ARD1 subunit-like protein K20791 NAA10_11; N-alpha-acetyltransferase 10/11 [EC:2.3.1.255]
D TTHERM_00218670 NMDA receptor-regulated protein K20792 NAA15_16; N-alpha-acetyltransferase 15/16, NatA auxiliary subunit
D TTHERM_00686140 acetyltransferase (GNAT) domain protein K20793 NAA50; N-alpha-acetyltransferase 50 [EC:2.3.1.258 2.3.1.309]
B Meiosis-specific proteins
C Cohesin complex and associated proteins
D TTHERM_01048090 SMC family, carboxy-terminal domain protein K06636 SMC1; structural maintenance of chromosome 1
C Synaptonemal complex
C DSB formation-related proteins
D TTHERM_00627090 type IIB DNA topoisomerase K10878 SPO11; meiotic recombination protein SPO11
C Others
D TTHERM_00459230 meiotic recombination protein DMC1, putative K10872 DMC1; meiotic recombination protein DMC1
D TTHERM_00763040 MutS domain V protein K08741 MSH5; DNA mismatch repair protein MSH5
B Nucleosome assembly factors
C Histones
D TTHERM_00316500 histone H2B.1 K11251 H2A; histone H2A
D TTHERM_00143660 histone H2A K11251 H2A; histone H2A
D TTHERM_00790790 histone H2A K11251 H2A; histone H2A
D TTHERM_00283180 histone H2B.1 K11252 H2B; histone H2B
D TTHERM_00633360 histone H2B.1 K11252 H2B; histone H2B
D TTHERM_00189180 hypothetical protein K11253 H3; histone H3
D TTHERM_00016170 histone H3.4 K11253 H3; histone H3
D TTHERM_00016200 histone H3.4 K11253 H3; histone H3
D TTHERM_000570549 histone H3.4 K11253 H3; histone H3
D TTHERM_00498190 hypothetical protein K11254 H4; histone H4
D TTHERM_00189170 histone H4 K11254 H4; histone H4
C Histone chaperones
D Nucleoplasmins
D NAPs (Nucleosome assembly proteins)
E TTHERM_00786930 nucleosome assembly protein K11279 NAP1L1; nucleosome assembly protein 1-like 1
E TTHERM_001048129 nucleosome assembly protein K11279 NAP1L1; nucleosome assembly protein 1-like 1
D CAF-1
E TTHERM_00219420 chromatin assembly factor 1 subunit FAS2 K10751 CHAF1B; chromatin assembly factor 1 subunit B
E TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
E TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
D FACT complex
E TTHERM_00049080 structure-specific recognition protein K09272 SSRP1; FACT complex subunit SSRP1/POB3
E TTHERM_00283330 metallopeptidase family M24 containing protein K25639 SUPT16H; FACT complex subunit SPT16
D Other Histone chaperones and regulators
E TTHERM_00442300 histone chaperone asf1 K10753 ASF1; histone chaperone ASF1
E TTHERM_01093550 zinc knuckle protein K11292 SUPT6H; transcription elongation factor SPT6
E TTHERM_00046490 TUP1-like enhancer of split protein K11293 HIRA; protein HIRA/HIR1
C HMG (high mobility group) proteins
B Histone modification proteins
C HATs (histone acetyltransferases)
D TTHERM_00046760 histone acetyl transferase HAT1 amine-terminal protein K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
D TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
D TTHERM_00145730 MOZ/SAS family protein K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D TTHERM_00310240 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D TTHERM_00145740 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
C HAT complexes
D PCAF complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00790730 Myb-like DNA-binding domain protein K11314 TADA2A; transcriptional adapter 2-alpha
E TTHERM_00227160 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E TTHERM_00787360 TATA box-binding protein associated factor K03131 TAF6; transcription initiation factor TFIID subunit 6
E TTHERM_000105239 transcription initiation factor TFIID 23-30 kDa subunit K03134 TAF10; transcription initiation factor TFIID subunit 10
D STAGA complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00227160 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E TTHERM_00787360 TATA box-binding protein associated factor K03131 TAF6; transcription initiation factor TFIID subunit 6
E TTHERM_000105239 transcription initiation factor TFIID 23-30 kDa subunit K03134 TAF10; transcription initiation factor TFIID subunit 10
E TTHERM_00530350 splicing factor 3B subunit 3 K12830 SF3B3; splicing factor 3B subunit 3
D TFTC complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00227160 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E TTHERM_00787360 TATA box-binding protein associated factor K03131 TAF6; transcription initiation factor TFIID subunit 6
E TTHERM_00703300 TAF7 RNA polymerase II, TATA box-binding protein K03132 TAF7; transcription initiation factor TFIID subunit 7
E TTHERM_000105239 transcription initiation factor TFIID 23-30 kDa subunit K03134 TAF10; transcription initiation factor TFIID subunit 10
E TTHERM_00530350 splicing factor 3B subunit 3 K12830 SF3B3; splicing factor 3B subunit 3
D TIP60 complex
E TTHERM_00145730 MOZ/SAS family protein K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E TTHERM_00357110 animal DNA methyltransferase 1 SANT/myb-like domain protein, putative K11324 DMAP1; DNA methyltransferase 1-associated protein 1
E TTHERM_00476820 holliday junction ATP-dependent DNA helicase RuvB K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
E TTHERM_00046920 TBP-interacting DNA helicase K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
E TTHERM_00561450 YEATS domain protein, putative K11341 YEATS4; YEATS domain-containing protein 4
D HBO1 complex
D MOZ/MORF complex
D SAGA complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00790730 Myb-like DNA-binding domain protein K11314 TADA2A; transcriptional adapter 2-alpha
E TTHERM_00227160 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E TTHERM_00787360 TATA box-binding protein associated factor K03131 TAF6; transcription initiation factor TFIID subunit 6
E TTHERM_000105239 transcription initiation factor TFIID 23-30 kDa subunit K03134 TAF10; transcription initiation factor TFIID subunit 10
E TTHERM_000295989 enhancer of yellow 2 transcription factor-like protein K11368 ENY2; enhancer of yellow 2 transcription factor
D SLIK complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00790730 Myb-like DNA-binding domain protein K11314 TADA2A; transcriptional adapter 2-alpha
E TTHERM_00227160 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E TTHERM_00787360 TATA box-binding protein associated factor K03131 TAF6; transcription initiation factor TFIID subunit 6
E TTHERM_000105239 transcription initiation factor TFIID 23-30 kDa subunit K03134 TAF10; transcription initiation factor TFIID subunit 10
D ADA-HAT complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00790730 Myb-like DNA-binding domain protein K11314 TADA2A; transcriptional adapter 2-alpha
D HAT-A2 complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00790730 Myb-like DNA-binding domain protein K11314 TADA2A; transcriptional adapter 2-alpha
D ATAC complex
E TTHERM_00248390 histone acetyltransferase GCN5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E TTHERM_00790730 Myb-like DNA-binding domain protein K11314 TADA2A; transcriptional adapter 2-alpha
E TTHERM_00292070 histone-like transcription factor and archaeal histone protein K21751 DR1; down-regulator of transcription 1
E TTHERM_00433690 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
D HATB complex
E TTHERM_00046760 histone acetyl transferase HAT1 amine-terminal protein K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
E TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
E TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
D NSL complex
E TTHERM_00310240 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E TTHERM_00145740 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E TTHERM_00433690 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
D MSL complex
E TTHERM_00310240 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E TTHERM_00145740 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D NuA3 complex
D NuA4 complex
E TTHERM_00145730 MOZ/SAS family protein K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E TTHERM_00561450 YEATS domain protein, putative K11341 YEATS4; YEATS domain-containing protein 4
E TTHERM_00357110 animal DNA methyltransferase 1 SANT/myb-like domain protein, putative K11324 DMAP1; DNA methyltransferase 1-associated protein 1
D SAS complex
C HDACs (histone deacetylases)
D Class I HDACs
E TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D Class II HDACs
E TTHERM_01014700 histone deacetylasehistone-like deacetylase family, classII protein K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D SIRTs (sirtuins, class III HDACs)
E TTHERM_00242580 SIR2 family transcriptional regulator K11416 SIRT6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
D Class IV HDACs
E TTHERM_00395710 histone deacetylase family protein K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
C HDAC complexes
D Sin3A-HDAC complex
E TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00450950 ubiquitin carboxyl-terminal hydrolase family protein K11644 SIN3A; paired amphipathic helix protein Sin3a
E TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
E TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
E TTHERM_00469050 Sin3 associated protein (SAP18) protein K14324 SAP18; histone deacetylase complex subunit SAP18
D BRAF-HDAC complex
E TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D REST complex
E TTHERM_00450950 ubiquitin carboxyl-terminal hydrolase family protein K11644 SIN3A; paired amphipathic helix protein Sin3a
E TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SHIP complex
E TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D MiDAC complex
E TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SMART complex
E TTHERM_00046350 LisH protein K04508 TBL1; transducin (beta)-like 1
D Other HDAC associated proteins
E TTHERM_00293440 zinc finger, C2HC5-type family protein K23398 TRIP4; activating signal cointegrator 1
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
E TTHERM_00486440 SET domain protein K22748 ATXR3; [histone H3]-lysine4 N-trimethyltransferase ATXR3 [EC:2.1.1.354]
E TTHERM_00239400 SET domain protein K22748 ATXR3; [histone H3]-lysine4 N-trimethyltransferase ATXR3 [EC:2.1.1.354]
D PRMTs (protein arginine metyltransferases)
E TTHERM_00219490 arginine N-methyltransferase K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
C HMT complexes
D COMPASS/SET1 complex
E TTHERM_000812918 WD domain, G-beta repeat protein K14962 WDR82; COMPASS component SWD2
E TTHERM_00433690 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
E TTHERM_000773133 SPRY domain protein K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E TTHERM_00082260 Dpy-30 motif protein K14965 DPY30; protein dpy-30
E TTHERM_00579000 Dpy-30 motif protein K14965 DPY30; protein dpy-30
D COMPASS/SET1 complex (yeast)
E TTHERM_000812918 WD domain, G-beta repeat protein K14962 WDR82; COMPASS component SWD2
E TTHERM_00433690 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
D MLL-HCF complex
E TTHERM_000773133 SPRY domain protein K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E TTHERM_00082260 Dpy-30 motif protein K14965 DPY30; protein dpy-30
E TTHERM_00579000 Dpy-30 motif protein K14965 DPY30; protein dpy-30
E TTHERM_00433690 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
D MLL3/MLL4 complex
E TTHERM_000773133 SPRY domain protein K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E TTHERM_00082260 Dpy-30 motif protein K14965 DPY30; protein dpy-30
E TTHERM_00579000 Dpy-30 motif protein K14965 DPY30; protein dpy-30
E TTHERM_00433690 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
D Dot1-containing complex
C Histone demethylases
D TTHERM_000780519 JmjC domain protein K11323 JMJD6; histone arginine demethylase JMJD6 [EC:1.14.11.-]
D TTHERM_00460680 cupin-like domain protein K19219 JMJD7; peptidyl-lysine (3S)-dioxygenase / protease [EC:1.14.11.63 3.4.-.-]
C Polycomb repressive complex (PRC) and associated proteins
D Canonical PRC1 (PRC1.2/1.4)
E TTHERM_00263030 zinc finger, C3HC4 type (RING finger) protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E PRC1.4 specific proteins
D Noncanonical PRC1 (PRC1.1)
E TTHERM_00263030 zinc finger, C3HC4 type (RING finger) protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E TTHERM_00426320 SCF ubiquitin ligase complex protein K03094 SKP1; S-phase kinase-associated protein 1
E TTHERM_01013330 S-phase kinase-associated protein 1A K03094 SKP1; S-phase kinase-associated protein 1
E TTHERM_00469400 Skp1 family, dimerization domain protein K03094 SKP1; S-phase kinase-associated protein 1
D Noncanonical PRC1 (PRC1.3/1.5)
E TTHERM_00263030 zinc finger, C3HC4 type (RING finger) protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E TTHERM_00780530 casein kinase II beta chain, putative K03115 CSNK2B; casein kinase II subunit beta
E TTHERM_00382120 DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
D Noncanonical PRC1 (PRC1.6)
E TTHERM_00263030 zinc finger, C3HC4 type (RING finger) protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E TTHERM_00433690 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
E TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D PRC2.1
E TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
E TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
D PRC2.2
E TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
E TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
D PR-DUB complex
E TTHERM_00239260 C2H2-type zinc-finger protein K09201 YY; transcription factor YY
D Other PRC associated proteins
C Sir proteins
D TTHERM_00526990 SIR2 family histone deacetylase, putative K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
D TTHERM_00313730 SIR2 family transcriptional regulator K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
D TTHERM_01018420 SIR2 family transcriptional regulator K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
D TTHERM_01018450 SIR2 family transcriptional regulator K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
C Other histone modification proteins
D TTHERM_000267919 RNA recognition motif protein K22611 SART3; squamous cell carcinoma antigen recognized by T-cells 3
D TTHERM_00492530 WD domain, G-beta repeat protein K24752 WDR70; WD repeat-containing protein 70
D TTHERM_00307710 prefoldin subunit K26537 UXT; protein UXT
B Chromosome condensation proteins
C Condensin I
D TTHERM_00812950 structural maintenance of chromosomes protein K06674 SMC2; structural maintenance of chromosome 2
D TTHERM_00554600 condensin complex subunit 2 K06676 BRRN1; condensin complex subunit 2
D TTHERM_00728870 condensin complex subunit 2 K06676 BRRN1; condensin complex subunit 2
D TTHERM_00540340 condensin complex subunit 2 K06676 BRRN1; condensin complex subunit 2
D TTHERM_00392760 non-SMC mitotic condensation complex subunit 1, amine-terminal protein K06677 YCS4; condensin complex subunit 1
D TTHERM_00486070 non-SMC mitotic condensation complex subunit 1, amine-terminal protein K06677 YCS4; condensin complex subunit 1
C Condensin II
D TTHERM_00812950 structural maintenance of chromosomes protein K06674 SMC2; structural maintenance of chromosome 2
C Other regulators of chromosome condensation
D TTHERM_00052080 DNA topoisomerase II K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D TTHERM_01335310 DNA topoisomerase K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D TTHERM_00825440 DNA topoisomerase IV K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D TTHERM_00456750 DNA topoisomerase IV K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
E TTHERM_00321740 kinesin motor domain protein K11498 CENPE; centromeric protein E
E TTHERM_00058290 hypothetical protein K11498 CENPE; centromeric protein E
E TTHERM_000300539 kinesin motor catalytic domain protein K11498 CENPE; centromeric protein E
D CPC (chromosomal passenger complex)
D KMN network proteins
E MIS12 complex
E NDC80 complex
F TTHERM_000161298 kinetochore protein Nuf2, putative K11548 NUF2; kinetochore protein Nuf2
D Mis6 complex
D COMA complex
D NMS complex
E NDC80 complex
F TTHERM_000161298 kinetochore protein Nuf2, putative K11548 NUF2; kinetochore protein Nuf2
E MIND kinetochore complex
D MIS16-MIS18 complex
E TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
E TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
D DASH complex
D CBF3 complex
E TTHERM_00426320 SCF ubiquitin ligase complex protein K03094 SKP1; S-phase kinase-associated protein 1
E TTHERM_01013330 S-phase kinase-associated protein 1A K03094 SKP1; S-phase kinase-associated protein 1
E TTHERM_00469400 Skp1 family, dimerization domain protein K03094 SKP1; S-phase kinase-associated protein 1
D Others
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
D Motor proteins
E TTHERM_00321740 kinesin motor domain protein K11498 CENPE; centromeric protein E
E TTHERM_00058290 hypothetical protein K11498 CENPE; centromeric protein E
E TTHERM_000300539 kinesin motor catalytic domain protein K11498 CENPE; centromeric protein E
E RZZ complex
E Dynein complex
F TTHERM_00046310 dynein heavy chain, cytoplasmic protein K10413 DYNC1H; dynein cytoplasmic 1 heavy chain
F TTHERM_00558310 cytoplasmic dynein 2 heavy chain 1 K10414 DYNC2H; dynein cytoplasmic 2 heavy chain
F TTHERM_00773750 cytoplasmic dynein intermediate chain K10415 DYNC1I; dynein cytoplasmic 1 intermediate chain
F TTHERM_00294940 cytoplasmic dynein 1 light intermediate chain 1 K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
F TTHERM_00283830 cytoplasmic dynein 2 light intermediate chain 1 K10417 DYNC2LI; dynein cytoplasmic 2 light intermediate chain
E TTHERM_00790940 kinesin motor catalytic domain protein K10393 KIF2_24; kinesin family member 2/24
E TTHERM_00429870 kinesin motor catalytic domain protein K10393 KIF2_24; kinesin family member 2/24
E TTHERM_00648540 kinesin motor catalytic domain protein K10393 KIF2_24; kinesin family member 2/24
D Protein kinases
E TTHERM_00085220 MEK kinase K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
E TTHERM_01443850 Serine/Threonine kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
E TTHERM_00191790 Serine/Threonine kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
E TTHERM_01076980 Serine/Threonine kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
E TTHERM_00470890 Serine/Threonine kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
E TTHERM_00992960 polo kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
E TTHERM_00467740 plant dual-specificity MAP kinase kinase family domain protein K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
D Others
C Other centromeric chromatin formation proteins
D Shugoshin
D PP2A (protein phosphatase 2A)
E TTHERM_00088160 serine/threonine protein phosphatase 2A K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E TTHERM_00686120 ser/thr phosphatase family protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E TTHERM_00339780 serine/threonine protein phosphatase 2A K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E TTHERM_000088159 serine/threonine protein phosphatase 2A K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E TTHERM_00686110 serine/threonine protein phosphatase 2A K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E TTHERM_01345810 serine/threonine protein phosphatase 2A K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E TTHERM_00355160 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E TTHERM_00334400 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E TTHERM_00616340 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E TTHERM_00053920 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E TTHERM_00766530 serine/threonine protein phosphatase 2A regulatory subunit A, putative K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E TTHERM_00600480 protein phosphatase PP2A regulatory subunit B K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E TTHERM_00621360 serine/threonine-protein phosphatase 2A regulatory subunit B subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E TTHERM_000382209 EF hand protein K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E TTHERM_00991560 protein phosphatase 2A regulatory B subunit, B56 family protein K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E TTHERM_01031160 protein phosphatase 2A regulatory B subunit, B56 family protein K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E TTHERM_01266070 protein phosphatase 2A regulatory B subunit, B56 family protein K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
D TTHERM_00705240 heterochromatin protein K11587 CBX5; chromobox protein 5
C MBPs (metylated DNA binding proteins)
C Other heterochromatin formation proteins
D TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_00450950 ubiquitin carboxyl-terminal hydrolase family protein K11644 SIN3A; paired amphipathic helix protein Sin3a
D TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
D TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
B Gene silencing
C RISC (RNA-induced silencing complex)
D TTHERM_00316189 dicer-related RNase III protein Dcr2p, putative K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
D TTHERM_00653810 piwi domain protein K02156 AUB; aubergine
D TTHERM_00203030 piwi-like protein K02156 AUB; aubergine
D TTHERM_00503901 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00600450 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00144830 piwi domain protein K02156 AUB; aubergine
D TTHERM_00449120 piwi domain protein K02156 AUB; aubergine
D TTHERM_00506900 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00506910 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00503912 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_000503900 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_01161040 piwi domain protein K02156 AUB; aubergine
D TTHERM_01132860 piwi domain protein K02156 AUB; aubergine
D TTHERM_00218280 TrmH family RNA methyltransferase K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
C piRNA pathway
D TTHERM_00653810 piwi domain protein K02156 AUB; aubergine
D TTHERM_00203030 piwi-like protein K02156 AUB; aubergine
D TTHERM_00503901 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00600450 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00144830 piwi domain protein K02156 AUB; aubergine
D TTHERM_00449120 piwi domain protein K02156 AUB; aubergine
D TTHERM_00506900 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00506910 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_00503912 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_000503900 piwi-like Twi9p protein K02156 AUB; aubergine
D TTHERM_01161040 piwi domain protein K02156 AUB; aubergine
D TTHERM_01132860 piwi domain protein K02156 AUB; aubergine
D TTHERM_00645780 XRN 5'-3' exonuclease amine-terminal protein K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D TTHERM_00522650 DEAD/DEAH-box helicase K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D TTHERM_00433810 small RNA 2'-O-methyltransferase K20798 HENMT1; small RNA 2'-O-methyltransferase [EC:2.1.1.386]
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
D RDRC (RNA-directed RNA polymerase complex)
E TTHERM_00853150 RNA-dependent RNA polymerase RdRP2 K11699 RDR; RNA-dependent RNA polymerase [EC:2.7.7.48]
D Other RNAi proteins
E TTHERM_00127080 exonuclease K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E TTHERM_00585450 ERI1 exoribonuclease K18418 ERI3; ERI1 exoribonuclease 3 [EC:3.1.-.-]
E TTHERM_00689820 exonuclease K18418 ERI3; ERI1 exoribonuclease 3 [EC:3.1.-.-]
C microRNA pathway
D Microprocessor complex
D RISC loading complex
E TTHERM_00316189 dicer-related RNase III protein Dcr2p, putative K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
D Other miRNA pathway proteins
C Transposable elements
B Centrosome formation proteins
C Centriole proteins
D TTHERM_00486800 rhodanese-like domain protein K16455 CEP41; centrosomal protein CEP41
D TTHERM_00499590 rhodanese-like domain protein K16455 CEP41; centrosomal protein CEP41
D TTHERM_00498010 C2 domain protein K16457 CEP76; centrosomal protein CEP76
D TTHERM_00079820 centrosomal protein, putative K16458 CEP104; centrosomal protein CEP104
D TTHERM_00584800 UvrB/UvrC domain protein K16458 CEP104; centrosomal protein CEP104
D TTHERM_00532450 centrosomal protein, putative K16459 CEP120; centrosomal protein CEP120
D TTHERM_01164140 hypothetical protein K16461 CEP135; centrosomal protein CEP135
D TTHERM_00384910 basal body centrin protein K16465 CETN1; centrin-1
D TTHERM_00371010 centrin, EF-hand protein K16465 CETN1; centrin-1
D TTHERM_00442810 EF-hand protein K16465 CETN1; centrin-1
D TTHERM_00006390 EF hand protein K16465 CETN1; centrin-1
D TTHERM_00187120 EF hand protein K16465 CETN1; centrin-1
D TTHERM_01020640 dynein 18 kDa light chain K16465 CETN1; centrin-1
D TTHERM_00670560 EF-hand protein K16465 CETN1; centrin-1
D TTHERM_000688379 EF-hand protein K16465 CETN1; centrin-1
D TTHERM_00194330 EF-hand protein K10840 CETN2; centrin-2
D TTHERM_01075620 dynein 18 kDa light chain, flagellar outer arm protein K10840 CETN2; centrin-2
D TTHERM_00523059 basal body centrin protein K16466 CETN3; centrin-3
D TTHERM_00600790 hypothetical protein K16475 LRRCC1; leucine-rich repeat and coiled-coil domain-containing protein 1
D TTHERM_00214750 hypothetical protein K16480 OFD1; oral-facial-digital syndrome 1 protein
D TTHERM_00726470 poly(ADP-ribose) polymerase family WGR domain protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D TTHERM_00030430 poly(ADP-ribose) polymerase family WGR domain protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D TTHERM_00726460 poly(ADP-ribose) polymerase family WGR domain protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D TTHERM_00823980 poly(ADP-ribose) polymerase family WGR domain protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D TTHERM_00865150 poly(ADP-ribose) polymerase family WGR domain protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D TTHERM_00388200 spindle assembly abnormal-like protein, putative K16487 SAS-6; spindle assembly abnormal protein 6
D TTHERM_00137600 spindle assembly abnormal-like protein, putative K16487 SAS-6; spindle assembly abnormal protein 6
D TTHERM_00052080 DNA topoisomerase II K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D TTHERM_01335310 DNA topoisomerase K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D TTHERM_00825440 DNA topoisomerase IV K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D TTHERM_00456750 DNA topoisomerase IV K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C Pericentriolar materials (PCM)
D Centriolar satellite
E TTHERM_01054280 bardet-biedl syndrome 4 protein K16531 BBS4; Bardet-Biedl syndrome 4 protein
E TTHERM_00529770 fop amine-terminal dimerization domain protein K16535 FOPNL; lisH domain-containing protein FOPNL
E TTHERM_00191639 hook-like protein K16536 HOOK3; protein HOOK3
E TTHERM_00214750 hypothetical protein K16480 OFD1; oral-facial-digital syndrome 1 protein
E TTHERM_00047650 progesterone immunomodulatory-binding factor 1, putative K16538 PIBF1; progesterone-induced-blocking factor 1
D Other PCM proteins
E TTHERM_00561280 hypothetical protein K16540 AZI1; 5-azacytidine-induced protein 1
E TTHERM_00237640 cytochrome d1 heme domain protein K16547 NEDD1; protein NEDD1
C Cyclins
D TTHERM_00293270 amine-terminal domain cyclin K05868 CCNB1; G2/mitotic-specific cyclin-B1
D TTHERM_00189230 amine-terminal domain cyclin K21770 CCNB2; G2/mitotic-specific cyclin-B2
D TTHERM_00693080 amine-terminal domain cyclin K21771 CCNB3; G2/mitotic-specific cyclin-B3
D TTHERM_00940290 amine-terminal domain cyclin K21777 CCNB; G2/mitotic-specific cyclin-B, other
D TTHERM_00425970 amine-terminal domain cyclin K21777 CCNB; G2/mitotic-specific cyclin-B, other
D TTHERM_00827080 amine-terminal domain cyclin K21777 CCNB; G2/mitotic-specific cyclin-B, other
D TTHERM_00842480 amine-terminal domain cyclin K21777 CCNB; G2/mitotic-specific cyclin-B, other
D TTHERM_00196590 amine-terminal domain cyclin K21777 CCNB; G2/mitotic-specific cyclin-B, other
D TTHERM_00194440 amine-terminal domain cyclin K21777 CCNB; G2/mitotic-specific cyclin-B, other
C Kinases and associated factors
D TTHERM_00318700 cyclin-dependent kinase-like protein K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
D TTHERM_00227280 cyclin-dependent kinase-like Serine/Threonine kinase family protein K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D TTHERM_00339880 cyclin-dependent kinase-like Serine/Threonine kinase family protein K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D TTHERM_00579320 glycogen synthase kinase-3 K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
D TTHERM_01443850 Serine/Threonine kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_00191790 Serine/Threonine kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_01076980 Serine/Threonine kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_00470890 Serine/Threonine kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_00992960 polo kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_00658860 CAMP-dependent kinase catalytic subunit K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00433420 CAMP-dependent kinase catalytic subunit K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00369640 Serine/Threonine kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00290770 Serine/Threonine kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00215950 Serine/Threonine kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00992710 Serine/Threonine kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00445970 Serine/Threonine kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00474370 Serine/Threonine kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D TTHERM_00825310 Serine/Threonine kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D Kinase anchoring protein
C Microtubules and associated factors
D gamma-tubulin ring complex
E TTHERM_00079520 tubulin gamma chain K10389 TUBG; tubulin gamma
E TTHERM_00426160 Spc97/Spc98 family protein K16569 TUBGCP2; gamma-tubulin complex component 2
E TTHERM_00112620 Spc97/Spc98 family protein K16570 TUBGCP3; gamma-tubulin complex component 3
E TTHERM_01220340 Spc97/Spc98 family protein K16571 TUBGCP4; gamma-tubulin complex component 4
E TTHERM_00237640 cytochrome d1 heme domain protein K16547 NEDD1; protein NEDD1
D Other tubulins
E TTHERM_00923000 tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E TTHERM_01054190 tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E TTHERM_00558620 tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E TTHERM_00647130 tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E TTHERM_00348510 tubulin K07375 TUBB; tubulin beta
E TTHERM_00834960 tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E TTHERM_00836580 tubulin K07375 TUBB; tubulin beta
E TTHERM_01104960 tubulin K07375 TUBB; tubulin beta
E TTHERM_01120580 tubulin K07375 TUBB; tubulin beta
E TTHERM_01620840 tubulin K07375 TUBB; tubulin beta
E TTHERM_00550910 tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E TTHERM_01104980 tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E TTHERM_01104970 tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E TTHERM_01001250 tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E TTHERM_01001260 tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E TTHERM_00335970 tubulin/FtsZ family, GTPase domain protein K10390 TUBD; tubulin delta
E TTHERM_00118700 tubulin/FtsZ family, GTPase domain protein K10391 TUBE; tubulin epsilon
D Dynactin complex
E TTHERM_00823400 CAP-gly domain protein K04648 DCTN1; dynactin 1
E TTHERM_00086970 dynamitin protein K10424 DCTN2; dynactin 2
E TTHERM_00977540 dynactin p62 subunit, putative K10426 DCTN4; dynactin 4
E TTHERM_00637740 dynactin 5 p25 K10427 DCTN5; dynactin 5
E TTHERM_00977650 hypothetical protein K10428 DCTN6; dynactin 6
E TTHERM_000977659 dynactin K10428 DCTN6; dynactin 6
E TTHERM_01020680 beta-centractin-like protein K16575 ACTR1; centractin
E TTHERM_00295070 actin K16576 ACTR10; actin-related protein 10
D BRISC complex
D Microtubule-associated proteins
E TTHERM_00112440 EB1 protein K10436 MAPRE; microtubule-associated protein, RP/EB family
E TTHERM_00133700 calponin-like domain protein K10436 MAPRE; microtubule-associated protein, RP/EB family
E TTHERM_00578710 EB1-like protein, putative K10436 MAPRE; microtubule-associated protein, RP/EB family
E TTHERM_00355780 alpha-tubulin N-acetyltransferase K19573 ATAT1; alpha-tubulin N-acetyltransferase 1 [EC:2.3.1.108]
C Augmin complex
C Centrosome duplication proteins
D Centriole replication proteins
E TTHERM_00145280 EF-hand protein K02183 CALM; calmodulin
E TTHERM_00630500 calmodulin 1 K02183 CALM; calmodulin
E TTHERM_00569490 EF-hand protein K02183 CALM; calmodulin
E TTHERM_00578790 dynein 18 kDa light chain, flagellar outer arm protein K02183 CALM; calmodulin
E TTHERM_00497600 EF-hand pair protein K02183 CALM; calmodulin
E TTHERM_01164140 hypothetical protein K16461 CEP135; centrosomal protein CEP135
E TTHERM_00194330 EF-hand protein K10840 CETN2; centrin-2
E TTHERM_01075620 dynein 18 kDa light chain, flagellar outer arm protein K10840 CETN2; centrin-2
E TTHERM_00214750 hypothetical protein K16480 OFD1; oral-facial-digital syndrome 1 protein
E TTHERM_00388200 spindle assembly abnormal-like protein, putative K16487 SAS-6; spindle assembly abnormal protein 6
E TTHERM_00137600 spindle assembly abnormal-like protein, putative K16487 SAS-6; spindle assembly abnormal protein 6
D Regulators of centriole replication
E TTHERM_00518680 GTP-binding protein YchF K19788 OLA1; obg-like ATPase 1
E TTHERM_00300410 GTP-binding protein YchF K19788 OLA1; obg-like ATPase 1
E TTHERM_00498010 C2 domain protein K16457 CEP76; centrosomal protein CEP76
E TTHERM_000833689 ADP-ribosylation factor family protein K07936 RAN; GTP-binding nuclear protein Ran
E TTHERM_00023980 GTP-binding nuclear protein Ran-1 K07936 RAN; GTP-binding nuclear protein Ran
E TTHERM_00013480 hypothetical protein K14290 XPO1; exportin-1
E TTHERM_00048940 CRM1 carboxy-terminal protein K14290 XPO1; exportin-1
D Other centrosome duplication proteins
E TTHERM_00277530 DNA replication factor Cdt1 K10727 CDT1; chromatin licensing and DNA replication factor 1
E TTHERM_01076960 crooked neck-like protein K12869 CRN; crooked neck
E TTHERM_00069420 DNA replication licensing factor MCM4 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
E TTHERM_00865050 origin recognition complex subunit 1, putative K02603 ORC1; origin recognition complex subunit 1
E TTHERM_00684560 origin recognition complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
C Nde1-Su48 complex
C LINC complex
C 3M complex
C Other centriole associated proteins
D TTHERM_00487090 fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D TTHERM_00120910 ADP-ribosylation factor(Arf)/Arf-like (ARL) small GTPase family protein K07943 ARL2; ADP-ribosylation factor-like protein 2
D TTHERM_00370910 ARF-like 2-binding protein BART protein K16742 ARL2BP; ADP-ribosylation factor-like protein 2-binding protein
D TTHERM_00266450 variable flagellar number 3, putative K16755 CCDC61; coiled-coil domain-containing protein 61
D TTHERM_00537180 hypothetical protein K16757 CCDC77; coiled-coil domain-containing protein 77
D TTHERM_00690020 coiled-coil protein, putative K16757 CCDC77; coiled-coil domain-containing protein 77
D TTHERM_00554270 MCM2/3/5 family protein K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D TTHERM_00092850 DNA replication licensing factor MCM4 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D TTHERM_00207240 hypothetical protein K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00066880 Rab-family small GTPase K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00083660 Ras family small GTPase K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00107200 small GTPase family Rab protein K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00083670 Ras family small GTPase K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00126950 Ras family small GTPase K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00727540 small guanosine triphosphatase family Ras-related in brain (Rab) family protein K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00431230 small guanosine triphosphatase family Ras family protein K07901 RAB8A; Ras-related protein Rab-8A
D TTHERM_00755750 survival motor neuron interacting protein K21763 MAPKBP1; mitogen-activated protein kinase binding protein 1
D TTHERM_00088010 AAA family ATPase K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D TTHERM_001016149 RNA methyltransferase, putative K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
C Spindle formation proteins
D TTHERM_00276060 CAS/CSE protein, carboxy-terminal protein K18423 CSE1; exportin-2 (importin alpha re-exporter)
D TTHERM_00790940 kinesin motor catalytic domain protein K10393 KIF2_24; kinesin family member 2/24
D TTHERM_00429870 kinesin motor catalytic domain protein K10393 KIF2_24; kinesin family member 2/24
D TTHERM_00648540 kinesin motor catalytic domain protein K10393 KIF2_24; kinesin family member 2/24
D TTHERM_00558320 kinesin motor catalytic domain protein K10398 KIF11; kinesin family member 11
D TTHERM_00637750 kinesin motor catalytic domain protein K10402 KIF20; kinesin family member 20
D TTHERM_00115410 kinesin motor catalytic domain protein K10405 KIFC1; kinesin family member C1
D TTHERM_000522699 kinesin motor catalytic domain protein K10405 KIFC1; kinesin family member C1
D TTHERM_00564430 kinesin motor catalytic domain protein K10405 KIFC1; kinesin family member C1
D TTHERM_00681890 kinesin motor catalytic domain protein K10405 KIFC1; kinesin family member C1
D TTHERM_00079000 importin subunit alpha, putative K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00621200 armadillo/beta-catenin repeat protein K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00592800 importin subunit alpha K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00048830 importin subunit alpha, putative K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00335950 importin subunit alpha, putative K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00591640 hypothetical protein K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00295620 armadillo/beta-catenin-like repeat protein K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00161640 importin subunit alpha, putative K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00185260 importin subunit alpha, putative K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00013590 hypothetical protein K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_01016220 importin subunit alpha K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00300130 hypothetical protein K15042 KPNA5_6; importin subunit alpha-6/7
D TTHERM_00013110 importin-beta amine-terminal domain protein K14293 KPNB1; importin subunit beta-1
D TTHERM_00071070 nucleoporin, putative K14297 NUP98; nuclear pore complex protein Nup98-Nup96
D TTHERM_000293459 nucleoporin, putative K14297 NUP98; nuclear pore complex protein Nup98-Nup96
D TTHERM_00243960 transmembrane protein, putative K14303 NUP160; nuclear pore complex protein Nup160
D TTHERM_00091770 transmembrane protein, putative K20724 TMEM33; transmembrane protein 33
D TTHERM_00895610 reticulon protein K20721 RTN1; reticulon-1
D TTHERM_00760520 platelet-activating factor acetylhydrolase Ib subunit alpha, putative K16794 PAFAH1B1; platelet-activating factor acetylhydrolase IB subunit alpha
D TTHERM_01217200 poly(A)+ RNA export protein K14298 RAE1; mRNA export factor
D TTHERM_01106220 mRNA export factor, putative K14298 RAE1; mRNA export factor
D TTHERM_000833689 ADP-ribosylation factor family protein K07936 RAN; GTP-binding nuclear protein Ran
D TTHERM_00023980 GTP-binding nuclear protein Ran-1 K07936 RAN; GTP-binding nuclear protein Ran
D TTHERM_00069250 targeting protein for Xklp2 protein K16812 TPX2; targeting protein for Xklp2
B Sister chromatid separation proteins
C Securin and associated proteins
C Separase
D TTHERM_00297160 peptidase family C50 protein K02365 ESP1; separase [EC:3.4.22.49]
C APC/C complex
D TTHERM_00824040 hypothetical protein K03348 APC1; anaphase-promoting complex subunit 1
D TTHERM_00825120 cullin family protein K03349 APC2; anaphase-promoting complex subunit 2
D TTHERM_00691880 tetratricopeptide repeat protein K03350 APC3; anaphase-promoting complex subunit 3
D TTHERM_000058799 anaphase-promoting complex subunit 5 K03352 APC5; anaphase-promoting complex subunit 5
D TTHERM_00327340 tetratricopeptide repeat protein K03353 APC6; anaphase-promoting complex subunit 6
D TTHERM_00736470 anaphase promoting complex subunit 8/cdc23 K03355 APC8; anaphase-promoting complex subunit 8
D TTHERM_00526690 anaphase-promoting complex, subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
D TTHERM_00522770 anaphase-promoting complex subunit 11 RING-H2 finger protein K03358 APC11; anaphase-promoting complex subunit 11
D TTHERM_00248420 WD domain, G-beta repeat protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
C Aurora kinases
D TTHERM_00455370 Serine/Threonine kinase domain protein K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
D TTHERM_00343420 plant dual-specificity MAP kinase kinase family domain protein K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
D TTHERM_00684590 plant dual-specificity MAP kinase kinase family domain protein K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
D Regulators of Aurora kinases
E TTHERM_00069250 targeting protein for Xklp2 protein K16812 TPX2; targeting protein for Xklp2
C TACC proteins
C Polo kinases
D TTHERM_01443850 Serine/Threonine kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_00191790 Serine/Threonine kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_01076980 Serine/Threonine kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_00470890 Serine/Threonine kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D TTHERM_00992960 polo kinase K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
C Early mitotic inhibitors
B Chromatin remodeling factors
C BAF complex
D TTHERM_00304150 SNF5/SMARCB 1/INI1 family protein K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D TTHERM_00584840 SWIRM domain protein K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D TTHERM_00925560 SWIB/MDM2 domain protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C PBAF complex
D TTHERM_00304150 SNF5/SMARCB 1/INI1 family protein K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D TTHERM_00584840 SWIRM domain protein K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D TTHERM_00925560 SWIB/MDM2 domain protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C GBAF(ncBAF) complex
D TTHERM_00584840 SWIRM domain protein K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D TTHERM_00925560 SWIB/MDM2 domain protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C CHRAC complex
D TTHERM_00137610 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00388250 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C RSF complex
D TTHERM_00137610 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00388250 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C WICH complex
D TTHERM_00137610 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00388250 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C B-WICH complex
D TTHERM_00137610 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00388250 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00105060 DEAD/DEAH-box helicase family protein K16911 DDX21; ATP-dependent RNA helicase DDX21 [EC:5.6.2.7]
D TTHERM_00046470 myosin K10356 MYO1; myosin I
D TTHERM_00529660 splicing factor 3B subunit 1 K12828 SF3B1; splicing factor 3B subunit 1
C NORC complex
D TTHERM_00137610 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00388250 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C BRF complex
D TTHERM_00137610 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00388250 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C NuRD complex
D TTHERM_00663829 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_00663840 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_00502610 class I histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_000647329 histone deacetylasehistone-like deacetylase family, classII protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
D TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
C NuRF complex
D TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
D TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
C NuRF complex (fruit fly)
D TTHERM_00137610 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00388250 SNF2 family amine-terminal protein K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D TTHERM_00688660 histone-binding protein RBBP4 or subunit C of Caf1 complex protein K10752 RBBP4; histone-binding protein RBBP4
D TTHERM_000709589 DnaJ domain protein K10752 RBBP4; histone-binding protein RBBP4
C CERF complex
C SRCAP complex
D TTHERM_01546860 SNF2 family amine-terminal protein K11661 SRCAP; helicase SRCAP/SWR1 [EC:5.6.2.-]
D TTHERM_01005190 actin K11662 ACTR6; actin-related protein 6
D TTHERM_00476820 holliday junction ATP-dependent DNA helicase RuvB K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D TTHERM_00046920 TBP-interacting DNA helicase K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D TTHERM_00357110 animal DNA methyltransferase 1 SANT/myb-like domain protein, putative K11324 DMAP1; DNA methyltransferase 1-associated protein 1
D TTHERM_00561450 YEATS domain protein, putative K11341 YEATS4; YEATS domain-containing protein 4
D TTHERM_01298590 HIT zinc finger protein K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
C INO80 complex
D TTHERM_00343570 SNF2 family amine-terminal domain protein K11665 INO80; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D TTHERM_00476820 holliday junction ATP-dependent DNA helicase RuvB K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D TTHERM_00046920 TBP-interacting DNA helicase K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D TTHERM_00133470 actin K11672 ACTR5; actin-related protein 5
D TTHERM_00311980 actin K11673 ACTR8; actin-related protein 8
C INO80 complex (yeast)
D TTHERM_00343570 SNF2 family amine-terminal domain protein K11665 INO80; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D TTHERM_00476820 holliday junction ATP-dependent DNA helicase RuvB K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D TTHERM_00046920 TBP-interacting DNA helicase K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D TTHERM_00133470 actin K11672 ACTR5; actin-related protein 5
D TTHERM_00311980 actin K11673 ACTR8; actin-related protein 8
C RSC complex
D TTHERM_01245640 HSA protein K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
C SWI/SNF complex
D TTHERM_01245640 HSA protein K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
D TTHERM_00304150 SNF5/SMARCB 1/INI1 family protein K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
C SWR1 complex
D TTHERM_01546860 SNF2 family amine-terminal protein K11661 SRCAP; helicase SRCAP/SWR1 [EC:5.6.2.-]
D TTHERM_00476820 holliday junction ATP-dependent DNA helicase RuvB K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D TTHERM_00046920 TBP-interacting DNA helicase K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D TTHERM_01005190 actin K11662 ACTR6; actin-related protein 6
D TTHERM_00561450 YEATS domain protein, putative K11341 YEATS4; YEATS domain-containing protein 4
D TTHERM_01298590 HIT zinc finger protein K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
D TTHERM_00357110 animal DNA methyltransferase 1 SANT/myb-like domain protein, putative K11324 DMAP1; DNA methyltransferase 1-associated protein 1
C ASTRA complex
D TTHERM_00476820 holliday junction ATP-dependent DNA helicase RuvB K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D TTHERM_00046920 TBP-interacting DNA helicase K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D TTHERM_00637610 telomere length regulation protein K11137 TELO2; telomere length regulation protein
C Other chromatin remodeling factors
D TTHERM_00193800 type III restriction enzyme, res subunit family protein K14437 CHD7; chromodomain-helicase-DNA-binding protein 7 [EC:5.6.2.-]
D TTHERM_00627150 SNF2 family amine-terminal protein K14440 SMARCAL1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-]
D TTHERM_01080500 helicase carboxy-terminal domain protein K14440 SMARCAL1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-]
D TTHERM_00361420 hypothetical protein K23408 CDCA7; cell division cycle-associated protein 7
#
AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
C HU (heat unstable protein)
C IHF (integration host factor)
C Other nucleoid associated proteins
B Chromosome partitioning proteins
C MukBEF complex
C Condensin-like complex
C Divisome proteins
C Inhibitors of FtsZ assembly
C Other chromosome partitioning proteins
D TTHERM_00295400 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmg protein K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 16, 2024