+F Repair protein KO #

  DNA Repair and Recombination Proteins - Toxoplasma gondii

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D TGME49_249810 activating signal cointegrator 1 complex subunit 3, putative K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] D TGME49_206400 FAD binding domain of DNA photolyase domain-containing protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E TGME49_307650 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E TGME49_313470 helix-hairpin-helix motif domain-containing protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E TGME49_305920 endonuclease III family 1 protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E TGME49_288680 endonuclease IV APN K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] D Long Patch-BER factors E DNA polymerase delta complex F TGME49_258030 DNA polymerase K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] F TGME49_233820 DNA polymerase epsilon subunit B protein K02328 POLD2; DNA polymerase delta subunit 2 F TGME49_254640 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4 E DNA polymerase epsilon complex F TGME49_319860 DNA polymerase family B protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] F TGME49_280690 DNA polymerase epsilon subunit B protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] E TGME49_320110 PCNA2; proliferating cell nuclear antigen PCNA2 K04802 PCNA; proliferating cell nuclear antigen E TGME49_247460 PCNA1; proliferating cell nuclear antigen PCNA1 K04802 PCNA; proliferating cell nuclear antigen E TGME49_251620 flap structure-specific endonuclease 1, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] E TGME49_208580 DNA ligase 1, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Short Patch-BER factors D Other BER factors E TGME49_208320 polynucleotide kinase 3 phosphatase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] E TGME49_270840 poly(ADP-ribose) polymerase catalytic domain-containing protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex F TGME49_295340 UV excision repair protein Rad23 protein K10839 RAD23; UV excision repair protein RAD23 E Cul4-DDB2 complex F TGME49_213690 ring box protein 1 family protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F TGME49_316660 cullin family protein K10609 CUL4; cullin 4 E NER4 complex F TGME49_226440 RAD16; SWI2/SNF2-containing protein RAD16 K15083 RAD16; DNA repair protein RAD16 D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex F TGME49_225260 POLR2A; DNA-directed RNA polymerase II RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] F TGME49_258210 DNA-directed RNA polymerase II RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] F TGME49_238190 POLR2C; DNA-directed RNA polymerase II RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 F TGME49_231380 POLR2D; DNA-directed RNA polymerase II RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 F TGME49_240590 POLR2E; DNA-directed RNA polymerase II RPB5 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 F TGME49_270780 POLR2F; DNA-directed RNA polymerase II RPB6 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 F TGME49_271300 POLR2G; DNA-directed RNA polymerase II RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 F TGME49_233720 POLR2H; DNA-directed RNA polymerase II RPBABC8 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 F TGME49_202690 POLR2I; DNA-directed RNA polymerase II RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 F TGME49_217560 POLR2L; DNA-directed RNA polymerase II RPB10 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 F TGME49_315920 POLR2J; DNA-directed RNA polymerase II RPB11A K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 F TGME49_254140 POLR2K; DNA-directed RNA polymerase II RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 E Cul4-CSA complex F TGME49_213690 ring box protein 1 family protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F TGME49_316660 cullin family protein K10609 CUL4; cullin 4 E Other TCR factor F TGME49_263140 RAD26; SWI2/SNF2-containing protein RAD26 K10841 ERCC6; DNA excision repair protein ERCC-6 F TGME49_297730 transcription elongation factor 1, putative K25829 ELOF1; transcription elongation factor 1 D TFIIH complex E TGME49_269660 TFIIH basal transcription factor complex helicase XPB subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] E TGME49_216870 DNA excision repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] E TGME49_294920 GTF2H2; general transcription factor IIH polypeptide 2 GTF2H2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 E TGME49_266930 GTF2H3; general transcription factor IIH polypeptide 3 GTF2H3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 E TGME49_214520 GTF2H4; general transcription factor IIH polypeptide 4 GTF2H4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 E TGME49_217450 GTF2H5; general transcription factor IIH polypeptide 5 GTF2H5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit E TGME49_270330 cell-cycle-associated protein kinase, putative K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] E TGME49_320070 CDK-activating kinase assembly factor MAT1 protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1 D RPA (replication factor A) E TGME49_236080 replication factor-a protein 1 (rpa1) subfamily protein K07466 RFA1; replication factor A1 E TGME49_253080 hypothetical protein K10739 RFA2; replication factor A2 E TGME49_238110 replication factor a protein 3 protein K10740 RPA3; replication factor A3 D Other NER factors E TGME49_249330 DNA repair protein rad10 subfamily protein K10849 ERCC1; DNA excision repair protein ERCC-1 E TGME49_268560 XPG N-terminal domain-containing protein K10846 ERCC5; DNA excision repair protein ERCC-5 E TGME49_208580 DNA ligase 1, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] E TGME49_201770 cullin 3, putative K03869 CUL3; cullin 3 C MMR (mismatch excision repair) D Mismatch and loop recognition factors E TGME49_261000 MutS domain V domain-containing protein K08735 MSH2; DNA mismatch repair protein MSH2 E TGME49_290640 DNA mismatch repair protein MSH6-1, putative K08737 MSH6; DNA mismatch repair protein MSH6 D MutL homologs E TGME49_236200 DNA mismatch repair protein, C-terminal domain-containing protein K10858 PMS2; DNA mismatch repair protein PMS2 D DNA polymerase delta complex E TGME49_258030 DNA polymerase K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] E TGME49_233820 DNA polymerase epsilon subunit B protein K02328 POLD2; DNA polymerase delta subunit 2 E TGME49_254640 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4 D RPA (replication factor A) E TGME49_236080 replication factor-a protein 1 (rpa1) subfamily protein K07466 RFA1; replication factor A1 E TGME49_253080 hypothetical protein K10739 RFA2; replication factor A2 E TGME49_238110 replication factor a protein 3 protein K10740 RPA3; replication factor A3 D RFC (replication factor C) E TGME49_235170 ATPase, AAA family protein K10754 RFC1; replication factor C subunit 1 E TGME49_237110 replication factor C subunit 2, putative K10755 RFC2_4; replication factor C subunit 2/4 E TGME49_210960 replication factor C subunit 4, putative K10755 RFC2_4; replication factor C subunit 2/4 E TGME49_273950 replication factor C subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5 E TGME49_213000 replication factor C, subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5 D Other MMR factors E TGME49_320110 PCNA2; proliferating cell nuclear antigen PCNA2 K04802 PCNA; proliferating cell nuclear antigen E TGME49_247460 PCNA1; proliferating cell nuclear antigen PCNA1 K04802 PCNA; proliferating cell nuclear antigen E TGME49_233090 XPG N-terminal domain-containing protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-] E TGME49_277150 XPG N-terminal domain-containing protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-] E TGME49_208580 DNA ligase 1, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex E TGME49_278060 Mre11 DNA-binding domain-containing protein K10865 MRE11; double-strand break repair protein MRE11 E TGME49_257180 RecF/RecN/SMC N terminal domain-containing protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex E TGME49_278060 Mre11 DNA-binding domain-containing protein K10865 MRE11; double-strand break repair protein MRE11 E TGME49_257180 RecF/RecN/SMC N terminal domain-containing protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] D BRCA complex E TGME49_272900 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51 D RecA family proteins E TGME49_272900 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51 D Rad52 family proteins D Rad54 family proteins E TGME49_232450 RAD54; SWI2/SNF2-containing protein RAD54 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] E TGME49_205402 SNF2 family N-terminal domain-containing protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] D RecQ family DNA helicases E TGME49_316300 ATP-dependent DNA helicase, RecQ family protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] D Bloom's syndrome complex (BTR) E TGME49_264450 DNA topoisomerase III beta-1, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E TGME49_226480 DNA topoisomerase family protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] D RPA (replication factor A) E TGME49_236080 replication factor-a protein 1 (rpa1) subfamily protein K07466 RFA1; replication factor A1 E TGME49_253080 hypothetical protein K10739 RFA2; replication factor A2 E TGME49_238110 replication factor a protein 3 protein K10740 RPA3; replication factor A3 D Protein phosphatase 4 E TGME49_286210 protein phosphatase 4, catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] E TGME49_272550 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3 D AP-5 complex E TGME49_248150 hypothetical protein K19025 AP5Z1; AP-5 complex subunit zeta-1 D SMC5-SMC6 complex E TGME49_216250 RecF/RecN/SMC N terminal domain-containing protein K22803 SMC5; structural maintenance of chromosomes protein 5 E TGME49_305760 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] D Other HR factors E TGME49_236920 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1 E TGME49_311060 metal-dependent phosphohydrolase HD domain-containing protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] C NHEJ (non-homologous end-joining) D DNA-PK complex E TGME49_248160 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 D MRX complex E TGME49_278060 Mre11 DNA-binding domain-containing protein K10865 MRE11; double-strand break repair protein MRE11 E TGME49_257180 RecF/RecN/SMC N terminal domain-containing protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] D DNA Ligase 4 complex E TGME49_293460 ATP-dependent DNA ligase domain-containing protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] D X-family DNA polymerases D Other NHEJ factors E TGME49_232310 endonuclease/exonuclease/phosphatase family protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) E TGME49_264450 DNA topoisomerase III beta-1, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E TGME49_226480 DNA topoisomerase family protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] D FANCD2-I complex D Downstream FA components D Other FA pathway factors E TGME49_272900 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51 C Other DSBR factors D Protein phosphatase 6 E TGME49_301010 serine/threonine protein phosphatase, putative K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] D Ubiquitin ligases D Others E TGME49_278730 guanine nucleotide-binding protein, putative K23314 WRAP53; telomerase Cajal body protein 1 E TGME49_257560 WD domain, G-beta repeat-containing protein K24752 WDR70; WD repeat-containing protein 70 B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D TGME49_237480 BRCA1 C Terminus (BRCT) domain-containing protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group D TGME49_216130 ubiquitin conjugating enzyme E2, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D TGME49_263490 ubiquitin conjugating enzyme E2, putative K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23] D TGME49_318480 RAD5; SWI2/SNF2-containing protein RAD5 K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-] D TGME49_310040 ubiquitin conjugating enzyme E2, putative K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant D TGME49_304770 ubiquitin-conjugating enzyme subfamily protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] C Other TLS factors D TGME49_320110 PCNA2; proliferating cell nuclear antigen PCNA2 K04802 PCNA; proliferating cell nuclear antigen D TGME49_247460 PCNA1; proliferating cell nuclear antigen PCNA1 K04802 PCNA; proliferating cell nuclear antigen B Check point factors C Rad9-Hus1-Rad1 complex D TGME49_206390 hypothetical protein K10903 HUS1; HUS1 checkpoint protein C HRAD17(Rad24)-RFC complex D TGME49_237110 replication factor C subunit 2, putative K10755 RFC2_4; replication factor C subunit 2/4 D TGME49_210960 replication factor C subunit 4, putative K10755 RFC2_4; replication factor C subunit 2/4 D TGME49_273950 replication factor C subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5 D TGME49_213000 replication factor C, subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5 C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex D TGME49_219080 edge expressed protein, putative K23387 GET4; golgi to ER traffic protein 4 C Other check point factors D TGME49_283702 FATC domain-containing protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] D TGME49_248530 FATC domain-containing protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] D TGME49_263090 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon D TGME49_269582 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon D TGME49_227952 14-3-3 superfamily protein K06630 YWHAE; 14-3-3 protein epsilon D TGME49_315680 vacuolar protein sorting-associated protein vps4, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4 B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex D TGME49_320210 WD domain, G-beta repeat domain containing protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] D TGME49_275480 Myb family DNA-binding domain-containing protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 D TGME49_243620 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27 D TGME49_218420 WD domain, G-beta repeat-containing protein K12862 PLRG1; pleiotropic regulator 1 C Modulation of nucleotide pools D TGME49_233140 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D TGME49_294640 ribonucleoside-diphosphate reductase large chain K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] D TGME49_207060 ribonucleoside-diphosphate reductase small subunit K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D TGME49_206400 FAD binding domain of DNA photolyase domain-containing protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E TGME49_307650 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E TGME49_313470 helix-hairpin-helix motif domain-containing protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E TGME49_305920 endonuclease III family 1 protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D RecJ D DNA ligase D DNA polymerase I C NER (nucleotide excision repair) D GGR (global genome repair) factors D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) E TRCF (transcription-repair coupling factor) C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases D DNA polymerase III holoenzyme D DNA ligase D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins D RecFOR pathway proteins D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F TGME49_221330 DNA gyrase/topoisomerase IV, A subunit domain-containing protein K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F TGME49_297780 ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] E Supressor D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway E Facilitator E Supressor B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C Other SOS response factors B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases C Modulation of nucleotide pools D TGME49_233140 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024