+D Protein KO
#
Membrane Trafficking - Toxoplasma gondii
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
C Phospholipases
D TGME49_248830 PIPLC; phosphoinositide phospholipase PIPLC K19006 PLCH; phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]
C Kinases and associated proteins
D TGME49_230490 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D TGME49_295350 nucleoside diphosphate kinase, putative K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D TGME49_202210 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
B Small GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D TGME49_249240 calmodulin, putative K02183 CALM; calmodulin
D TGME49_269442 calmodulin, putative K02183 CALM; calmodulin
D TGME49_297680 calmodulin, putative K02183 CALM; calmodulin
D TGME49_262010 CAM2; calmodulin CAM2 K02183 CALM; calmodulin
D TGME49_311260 myosin light chain MLC1, putative K02183 CALM; calmodulin
D TGME49_226040 EF hand domain-containing protein K02183 CALM; calmodulin
D TGME49_305050 calmodulin, putative K02183 CALM; calmodulin
D TGME49_240740 Sec1 family protein K15292 STXBP1; syntaxin-binding protein 1
D TGME49_217650 hypothetical protein K19942 GAS8; dynein regulatory complex subunit 4
D TGME49_248225 PF2 arrest specific protein 8/11, putative K19942 GAS8; dynein regulatory complex subunit 4
D TGME49_261200 TBC domain-containing protein K19953 GRTP1; TBC1 domain family member 6
D TGME49_231870 tetratricopeptide repeat-containing protein K13342 PEX5; peroxin-5
D TGME49_316270 Rab geranylgeranyl transferase type II beta subunit, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D TGME49_278230 prenyltransferase and squalene oxidase repeat-containing protein K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
C Rho GTPases
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
C Exocyst complex assembly proteins
D TGME49_236920 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
B Others
C Exomer complex
C Others
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D TGME49_209820 syntaxin protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D TGME49_247930 SNARE domain-containing protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D TGME49_226600 syntaxin 5, putative K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D TGME49_242080 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
D TGME49_311320 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
D TGME49_278160 vesicle transport V-snare protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
D TGME49_306640 hypothetical protein K08494 NSPN; novel plant SNARE
C Gos1 (Gos28)
C Bos1 / Membrin
D TGME49_223620 golgi SNARE, putative K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
B SNAP-25[C] (Qc)
C STX6
C STX8
C STX10
C Bet1
D TGME49_205030 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D TGME49_257520 synaptobrevin protein K08515 VAMP7; vesicle-associated membrane protein 7
D TGME49_230430 vesicle-associated membrane protein, putative K08515 VAMP7; vesicle-associated membrane protein 7
D TGME49_248100 synaptobrevin protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D TGME49_299180 prenylated protein, putative K08516 YKT6; synaptobrevin homolog YKT6
D TGME49_215420 SNARE protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D TGME49_270070 synaptobrevin family protein K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D TGME49_240740 Sec1 family protein K15292 STXBP1; syntaxin-binding protein 1
D TGME49_213072 Sec1 family protein K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D TGME49_278850 DHHC zinc finger domain-containing protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D TGME49_250870 DHHC zinc finger domain-containing protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D TGME49_252200 cell cycle regulator with zn-finger domain-containing protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D TGME49_301370 DHHC zinc finger domain-containing protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D TGME49_217870 DHHC zinc finger domain-containing protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D TGME49_269150 DHHC zinc finger domain-containing protein K20029 ZDHHC3_7_25; palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]
D TGME49_255650 DHHC zinc finger domain-containing protein K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D TGME49_272320 DHHC zinc finger domain-containing protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D TGME49_318510 N-ethylmaleimide-sensitive fusion protein, putative K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D TGME49_218760 SNAP protein (soluble N-ethylmaleimide-sensitive factor Attachment Protein), putative K15296 NAPA; alpha-soluble NSF attachment protein
D TGME49_320690 gamma-soluble NSF attachment protein, putative K21198 NAPG; gamma-soluble NSF attachment protein
D TGME49_273090 CDC48CY; cell division protein CDC48CY K13525 VCP; transitional endoplasmic reticulum ATPase
D TGME49_220500 UBX domain-containing protein K14012 NSFL1C; UBX domain-containing protein 1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D TGME49_290950 clathrin heavy chain, putative K04646 CLTC; clathrin heavy chain
C Dynamin
D TGME49_267800 DRPA; dynamin-related protein DRPA K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D TGME49_221940 adaptin n terminal region domain-containing protein K11824 AP2A; AP-2 complex subunit alpha
D TGME49_230920 adaptor complexes medium subunit family protein K11826 AP2M1; AP-2 complex subunit mu-1
D TGME49_313450 AP-2 complex subunit sigma-1, putative K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D TGME49_214180 ENTH domain-containing protein K12471 EPN; epsin
D TGME49_273760 HSP70; heat shock protein HSP70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D TGME49_230490 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
C Kinases
D TGME49_236240 Tyrosine kinase-like (TKL) protein K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D TGME49_222960 SCY kinase-related protein (incomplete catalytic triad) K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
C Others
D TGME49_310320 calreticulin family protein K08054 CANX; calnexin
D TGME49_263330 Adaptin ear-binding coat-associated protein 2 (NECAP-2) isoform 2 family protein K20069 NECAP1_2; adaptin ear-binding coat-associated protein 1/2
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D TGME49_267800 DRPA; dynamin-related protein DRPA K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
C Arf6-dependent endocytosis
C RhoA-dependent endocytosis
D TGME49_267800 DRPA; dynamin-related protein DRPA K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D TGME49_263180 myosin D K10356 MYO1; myosin I
D TGME49_255190 myosin C K10356 MYO1; myosin I
D TGME49_235470 myosin A K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
C Kinases
C Phospholipase C
D TGME49_248830 PIPLC; phosphoinositide phospholipase PIPLC K19006 PLCH; phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]
C Sorting nexins
D TGME49_309870 hypothetical protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
C F-BAR proteins
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D TGME49_219720 Ras-related protein Rab-5C, putative K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D TGME49_230140 vacuolar sorting protein 9 (vps9) domain-containing protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D TGME49_271060 Sec1 family protein K12479 VPS45; vacuolar protein sorting-associated protein 45
D TGME49_249380 DHHC zinc finger domain-containing protein K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]
B Arf GTPases and associated proteins
C Arf GTPases
C Arf associated proteins
D TGME49_309220 GTPase activating protein for Arf protein K12486 SMAP; stromal membrane-associated protein
D TGME49_237280 TLD protein K21841 TBC1D24; TBC1 domain family member 24
D TGME49_253000 ELMO/CED-12 family protein K23538 ELMOD; ELMO domain-containing protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D TGME49_219720 Ras-related protein Rab-5C, putative K07889 RAB5C; Ras-related protein Rab-5C
D TGME49_248880 RAB7; GTPase RAB7 K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D TGME49_242660 vacuolar sorting protein 35, putative K18468 VPS35; vacuolar protein sorting-associated protein 35
D TGME49_252490 vacuolar protein sorting 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
D TGME49_263500 vacuolar protein sorting-associated protein 26, putative K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
C Rab associated proteins
D TGME49_258150 proteasome subunit alpha type 7, putative K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D TGME49_275350 TBC domain-containing protein K18469 TBC1D5; TBC1 domain family member 5
D TGME49_264760 Oxysterol-binding protein K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
D TGME49_294320 Oxysterol-binding protein K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
D TGME49_316270 Rab geranylgeranyl transferase type II beta subunit, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D TGME49_278230 prenyltransferase and squalene oxidase repeat-containing protein K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
B Arf GTPases and associated proteins
C Arf GTPases
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
C ESCRT-II complex
C ESCRT-III complex
D TGME49_315350 SNF7 family protein K12197 CHMP1; charged multivesicular body protein 1
D TGME49_220460 SNF7 family protein K12191 CHMP2A; charged multivesicular body protein 2A
D TGME49_248310 SNF7 family protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D TGME49_315680 vacuolar protein sorting-associated protein vps4, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
B Tethering complex
C CORVET complex
D TGME49_230220 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D TGME49_320670 vacuolar protein sorting 16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D TGME49_289730 Pep3/Vps18/deep orange family protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D TGME49_295000 hypothetical protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D TGME49_230220 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D TGME49_320670 vacuolar protein sorting 16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D TGME49_289730 Pep3/Vps18/deep orange family protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D TGME49_295000 hypothetical protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D TGME49_315530 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
B Acidification regulators
C Rabconnectin-3 complex
C RAVE complex
D TGME49_207680 suppressor of kinetochore protein 1, putative K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D TGME49_309370 adaptin n terminal region domain-containing protein K12396 AP3D; AP-3 complex subunit delta
D TGME49_269480 adaptor complexes medium subunit family protein K12398 AP3M; AP-3 complex subunit mu
D TGME49_215130 adaptor-related protein complex 3, sigma 2 subunit K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D TGME49_291120 trafficking protein mon1 subfamily protein K20195 MON1; vacuolar fusion protein MON1
D TGME49_207960 hypothetical protein K27045 CCZ1; vacuolar fusion protein CCZ1, animal type
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D TGME49_283530 small rab-related GTPase K06234 RAB23; Ras-related protein Rab-23
C Rab4 associated proteins
D TGME49_247600 hypothetical protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D TGME49_263360 WD domain, G-beta repeat-containing protein K20241 WDR44; WD repeat-containing protein 44
D TGME49_201700 WD domain, G-beta repeat-containing protein K14004 SEC13; protein transport protein SEC13
D TGME49_218870 TBC domain-containing protein K20242 EVI5; ecotropic viral integration site 5 protein
C Other Rab GTPase associated proteins
D TGME49_231210 sarcalumenin/eps15 family protein K12483 EHD1; EH domain-containing protein 1
D TGME49_230140 vacuolar sorting protein 9 (vps9) domain-containing protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D TGME49_272900 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D TGME49_305560 Vps51/Vps67 protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D TGME49_258832 Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D TGME49_297230 Vps53 family, N-terminal protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D TGME49_219290 F-actin-capping protein subunit beta, putative K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D TGME49_252490 vacuolar protein sorting 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D TGME49_319910 WD domain, G-beta repeat-containing protein K23289 EIPR1; EARP and GARP complex-interacting protein 1
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D TGME49_310460 Rab6 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D TGME49_262480 dynein light chain roadblock-type 2, putative K10419 DYNLRB; dynein light chain roadblock-type
D TGME49_291180 hypothetical protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D TGME49_262860 ADP-ribosylation factor family protein 1, putative K07942 ARL1; ADP-ribosylation factor-like protein 1
C Arf GTPase associated proteins
D TGME49_225310 ARF1-directed GTPase-activating protein, putative K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D TGME49_273070 GTPase activating protein for adp ribosylation factor, putative K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D TGME49_309220 GTPase activating protein for Arf protein K12486 SMAP; stromal membrane-associated protein
D TGME49_228660 Sec7 domain-containing protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D TGME49_306410 hypothetical protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D TGME49_240540 hypothetical protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D TGME49_305560 Vps51/Vps67 protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D TGME49_258832 Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D TGME49_297230 Vps53 family, N-terminal protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C TRAPP complex II
D TGME49_247648 Sybindin family protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D TGME49_222920 mbp-1 interacting protein-2a family protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D TGME49_314720 Sedlin, N-terminal region protein, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D TGME49_299200 Bet3 transport protein, putative K20302 TRAPPC3; trafficking protein particle complex subunit 3
D TGME49_293050 sybindin family protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D TGME49_269140 transport protein particle component, Bet3 domain-containing protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D TGME49_209080 transport protein particle (trapp) component, bet3 protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D TGME49_257020 hypothetical protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D TGME49_313670 adaptin n terminal region domain-containing protein K12391 AP1G1; AP-1 complex subunit gamma-1
D TGME49_240870 beta adaptin protein, putative K12392 AP1B1; AP-1 complex subunit beta-1
D TGME49_289770 mu1 adaptin K12393 AP1M; AP-1 complex subunit mu
D TGME49_270370 clathrin assembly protein AP19, putative K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D TGME49_309370 adaptin n terminal region domain-containing protein K12396 AP3D; AP-3 complex subunit delta
D TGME49_269480 adaptor complexes medium subunit family protein K12398 AP3M; AP-3 complex subunit mu
D TGME49_215130 adaptor-related protein complex 3, sigma 2 subunit K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
D TGME49_244290 adapter-related protein K12400 AP4E1; AP-4 complex subunit epsilon-1
D TGME49_207390 coatomer protein complex, gamma sub-unit, putative K12402 AP4M1; AP-4 complex subunit mu-1
D TGME49_314418 clathrin adaptor complex small chain family protein K12403 AP4S1; AP-4 complex subunit sigma-1
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D TGME49_230490 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D TGME49_225500 hypothetical protein K20318 SYS1; protein SYS1
D TGME49_319550 membrane protein C17G8.08c, putative K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D TGME49_251400 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D TGME49_214230 Dopey, N-terminal domain-containing protein K26680 DOP1; protein dopey
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D TGME49_215060 small GTP-binding protein sar1, putative K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D TGME49_201700 WD domain, G-beta repeat-containing protein K14004 SEC13; protein transport protein SEC13
D TGME49_311400 WD domain, G-beta repeat-containing protein K14005 SEC31; protein transport protein SEC31
D TGME49_291680 Sec23/Sec24 trunk domain-containing protein K14006 SEC23; protein transport protein SEC23
D TGME49_277000 transport protein Sec24, putative K14007 SEC24; protein transport protein SEC24
C TRAPP complex I
D TGME49_247648 Sybindin family protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D TGME49_222920 mbp-1 interacting protein-2a family protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D TGME49_314720 Sedlin, N-terminal region protein, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D TGME49_299200 Bet3 transport protein, putative K20302 TRAPPC3; trafficking protein particle complex subunit 3
D TGME49_293050 sybindin family protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D TGME49_269140 transport protein particle component, Bet3 domain-containing protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D TGME49_209080 transport protein particle (trapp) component, bet3 protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D TGME49_238100 transmembrane protein K20346 TMED4_9_11; p24 family protein alpha
D TGME49_310750 emp24/gp25L/p24 family protein K20347 TMED2; p24 family protein beta-1
D TGME49_237250 hypothetical protein K20347 TMED2; p24 family protein beta-1
D TGME49_289800 hypothetical protein K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D TGME49_211680 protein disulfide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D TGME49_224060 thioredoxin, putative K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D TGME49_218470 protein disulfide-isomerase, putative K09582 PDIA4; protein disulfide-isomerase A4 [EC:5.3.4.1]
D TGME49_249270 protein disulfide isomerase-related protein (provisional), putative K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D TGME49_214770 small GTP binding protein rab1a, putative K07874 RAB1A; Ras-related protein Rab-1A
D TGME49_258130 Rab1 protein K07874 RAB1A; Ras-related protein Rab-1A
D TGME49_312050 small GTPase Rab2, putative K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D TGME49_214810 hypothetical protein K20359 RABAC1; PRA1 family protein 1
D TGME49_285730 TBC domain containing protein K20360 TBC1D22; TBC1 domain family member 2
D TGME49_268720 Hrf1 family protein K20362 YIF1; protein transport protein YIF1
D TGME49_288900 Yos1 family protein K22939 IER3IP1; immediate early response 3-interacting protein 1
C ER-Golgi intermediate compartment (ERGIC) proteins
D TGME49_311720 chaperonin protein BiP K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D TGME49_240650 coatomer protein complex, subunit alpha, putative K05236 COPA; coatomer subunit alpha
D TGME49_266990 beta-COP K17301 COPB1; coatomer subunit beta
D TGME49_235020 COPI protein, putative K17302 COPB2; coatomer subunit beta'
D TGME49_273370 coatomer gamma 2-subunit protein, putative K17267 COPG; coatomer subunit gamma
D TGME49_221522 adaptor complexes medium subunit family protein K20471 COPD; coatomer subunit delta
D TGME49_244390 coatomer epsilon subunit protein K17268 COPE; coatomer subunit epsilon
D TGME49_280550 clathrin adaptor complex small chain subfamily protein K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
C Golgi to ER traffic proteins (GET)
D TGME49_231190 arsenite-activated ATPase family protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D TGME49_219080 edge expressed protein, putative K23387 GET4; golgi to ER traffic protein 4
C Rab GTPases
D TGME49_310460 Rab6 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D TGME49_256000 endoplasmic reticulum retention receptor K10949 KDELR; ER lumen protein retaining receptor
D TGME49_294040 KDEL endoplasmic reticulum proteinretention receptor 2 (KDELR2), putative K10949 KDELR; ER lumen protein retaining receptor
D TGME49_206350 ER-retrevial receptor Ter1p, putative K10949 KDELR; ER lumen protein retaining receptor
D TGME49_276910 endoplasmic reticulum lumen protein retaining receptor (ERD2) family protein K10949 KDELR; ER lumen protein retaining receptor
D TGME49_285730 TBC domain containing protein K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D TGME49_264760 Oxysterol-binding protein K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
D TGME49_294320 Oxysterol-binding protein K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
C FXYD proteins
C YIPF proteins
D TGME49_293300 Yip1 domain-containing protein K22940 YIPF1_2; protein YIPF1/2
D TGME49_214110 protein yipf5, putative K20363 YIPF5_7; protein YIPF5/7
D TGME49_250740 Yip1 domain-containing protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D TGME49_205740 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D TGME49_267840 tetratricopeptide repeat-containing protein K23563 EMC2; ER membrane protein complex subunit 2
D TGME49_230100 membrane protein, putative K23564 EMC3; ER membrane protein complex subunit 3
D TGME49_259000 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D TGME49_293200 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D TGME49_239690 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
D TGME49_243390 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
D TGME49_249310 hypothetical protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
C SEC61 complex
D TGME49_269980 preprotein translocase Sec61, putative K10956 SEC61A; protein transport protein SEC61 subunit alpha
D TGME49_211040 Sec61beta family protein K09481 SEC61B; protein transport protein SEC61 subunit beta
D TGME49_230380 protein translocation complex, SEC61 gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D TGME49_310870 integral membrane protein, putative K21891 TMCO1; calcium load-activated calcium channel
D TGME49_235660 hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
D TGME49_226270 hypothetical protein K26498 TMEM147; BOS complex subunit TMEM147
D TGME49_231130 hypothetical protein K26499 NCLN; BOS complex subunit NCLN
C Post-GPI attachment to proteins factors (PGAP)
C Others
D TGME49_213072 Sec1 family protein K19998 SCFD1; sec1 family domain-containing protein 1
D TGME49_270270 hypothetical protein K20724 TMEM33; transmembrane protein 33
D TGME49_315210 rhoptry protein, putative K23555 LMF1; lipase maturation factor 1
D TGME49_315220 ROP14; rhoptry protein ROP14 K23555 LMF1; lipase maturation factor 1
D TGME49_315940 rhoptry protein, putative K23555 LMF1; lipase maturation factor 1
D TGME49_231030 hypothetical protein K21848 ARV1; lipid intermediate transporter
D TGME49_314970 root hair defective 3 gtp-binding protein (rhd3) protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D TGME49_273790 hypothetical protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
C PI3K complex
D TGME49_221360 hypothetical protein K08334 BECN; beclin
C ATG9 transmembrane protein
D TGME49_260640 autophagy protein apg9 protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
C Atg12 conjugation proteins
D TGME49_229690 autophagy-related protein 7 atg7, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
C Atg8 conjugation proteins
D TGME49_254120 autophagy-related protein 8 atg8, putative K08341 GABARAP; GABA(A) receptor-associated protein
D TGME49_229690 autophagy-related protein 7 atg7, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D TGME49_236110 autophagy-related protein 3 atg3, putative K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D TGME49_297970 aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
C Other Cvt associated proteins
B Mitophagy
C Cargo receptors
C Scaffold proteins
C PINK1-Parkin associated proteins
C Other mitophagy associated proteins
D TGME49_265450 hexokinase K00844 HK; hexokinase [EC:2.7.1.1]
B Pexophagy
C Selective cargos
C Cargo receptors
C Other pexophagy associated proteins
D TGME49_308960 ATPase, AAA family protein K13338 PEX1; peroxin-1
D TGME49_255210 ATPase, AAA family protein K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D TGME49_273090 CDC48CY; cell division protein CDC48CY K13525 VCP; transitional endoplasmic reticulum ATPase
D TGME49_265380 tetratricopeptide repeat (TPR)-/U-box domain-containing protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D TGME49_236040 fructose-1,6-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D TGME49_236050 fructose-bisphosphate aldolase, putative K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D TGME49_248600 aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D TGME49_289690 GAPDH1; glyceraldehyde-3-phosphate dehydrogenase GAPDH1 K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D TGME49_297060 PGMII; phosphoglycerate mutase PGMII K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D TGME49_256760 PYKI; pyruvate kinase PyK1 K00873 PK; pyruvate kinase [EC:2.7.1.40]
D TGME49_299070 PYKII; pyruvate kinase PyKII K00873 PK; pyruvate kinase [EC:2.7.1.40]
D TGME49_223680 ubiquitin family protein K04523 UBQLN; ubiquilin
D TGME49_240700 ubiquitin family protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D TGME49_273760 HSP70; heat shock protein HSP70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D TGME49_288380 HSP90; heat shock protein HSP90 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
D TGME49_232660 HIP; Hsp70 interacting protein HIP K09560 ST13; suppressor of tumorigenicity protein 13
C Other CMA associated proteins
D TGME49_286420 elongation factor 1-alpha (EF-1-ALPHA), putative K03231 EEF1A; elongation factor 1-alpha
D TGME49_294800 elongation factor 1-alpha (EF-1-ALPHA), putative K03231 EEF1A; elongation factor 1-alpha
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D TGME49_318160 MSP (Major sperm protein) domain-containing protein K10707 VAPB; vesicle-associated membrane protein-associated protein B
C mTORC1 complex
C mTORC2 complex
C SEACIT/GATOR1 complex
C SEACAT/GATOR2 complex
D TGME49_201700 WD domain, G-beta repeat-containing protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D TGME49_214770 small GTP binding protein rab1a, putative K07874 RAB1A; Ras-related protein Rab-1A
D TGME49_258130 Rab1 protein K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
C Others
D TGME49_233905 histone kinase SNF1, putative K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D TGME49_224220 serine/threonine-protein phosphatase PP2A catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D TGME49_215170 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, putative K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D TGME49_218250 TAP42 family protein K17606 IGBP1; immunoglobulin-binding protein 1
D TGME49_227570 transmembrane amino acid transporter protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D TGME49_227580 transmembrane amino acid transporter protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D TGME49_227430 transmembrane amino acid transporter protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D TGME49_220160 WD domain-containing protein K22991 WDR45; WD repeat-containing protein 45
D TGME49_288600 WD domain, G-beta repeat-containing protein K22991 WDR45; WD repeat-containing protein 45
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
B Actin-binding proteins
C Myosins
D TGME49_263180 myosin D K10356 MYO1; myosin I
D TGME49_255190 myosin C K10356 MYO1; myosin I
D TGME49_235470 myosin A K10356 MYO1; myosin I
D TGME49_243250 myosin H K10357 MYO5; myosin V
C Arp2/3 complex
C Nucleation-promoting factors (NPFs)
C Others
D TGME49_220400 ADF; actin depolymerizing factor ADF K05765 CFL; cofilin
D TGME49_310030 cyclase-associated protein, putative K17261 CAP1_2; adenylyl cyclase-associated protein
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
C Lipid droplets
D TGME49_313190 Rab18/RabC-family small GTPase K07910 RAB18; Ras-related protein Rab-18
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D TGME49_233300 RhoGAP domain-containing protein K18470 ARHGAP1; Rho GTPase-activating protein 1
C Rho guanine nucleotide exchange factors (GEFs)
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 15, 2024