+F Repair protein KO
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DNA Repair and Recombination Proteins - Thioalkalivibrio sulfidiphilus
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Tgr7_0852 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Tgr7_1394 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Tgr7_2945 A/G-specific DNA-adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Tgr7_2633 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
E Tgr7_2438 ERCC4 domain-containing protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Tgr7_0883 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Tgr7_0781 mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Tgr7_0103 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Tgr7_0852 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Tgr7_1394 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Tgr7_1396 DNA photolyase K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E Tgr7_1908 conserved hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Tgr7_2152 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Tgr7_2945 A/G-specific DNA-adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Tgr7_2619 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Tgr7_0319 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Tgr7_3176 DNA-(apurinic or apyrimidinic site) lyase / endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E Tgr7_2633 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Tgr7_0007 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Tgr7_0109 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Tgr7_3179 Deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E Tgr7_1460 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Tgr7_2024 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Tgr7_0087 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Tgr7_2295 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E Tgr7_1444 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E Tgr7_1759 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E Tgr7_1907 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E Tgr7_0080 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Tgr7_2850 conserved hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Tgr7_0087 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Tgr7_2024 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Tgr7_2331 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Tgr7_2330 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Tgr7_2299 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Tgr7_3186 RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Tgr7_1358 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Tgr7_1282 DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E Tgr7_2159 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E Tgr7_0895 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E Tgr7_1034 Exodeoxyribonuclease VII K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Tgr7_0834 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Tgr7_1176 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Tgr7_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Tgr7_2141 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E Tgr7_2277 DNA-directed DNA polymerase K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Tgr7_1828 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Tgr7_3130 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Tgr7_0956 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Tgr7_1024 exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Tgr7_1073 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Tgr7_2024 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Tgr7_0080 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Tgr7_2850 conserved hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Tgr7_2293 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Tgr7_2820 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Tgr7_1287 recA protein K03553 recA; recombination protein RecA
E Tgr7_2235 DNA recombination protein, RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Tgr7_2234 Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Tgr7_2236 Crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Tgr7_0275 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E Tgr7_1287 recA protein K03553 recA; recombination protein RecA
E Tgr7_0841 Methylated-DNA--(protein)-cysteine S-methyltransferase K04485 radA; DNA repair protein RadA/Sms
E Tgr7_0003 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Tgr7_3183 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Tgr7_1460 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Tgr7_1094 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Tgr7_1075 recombination protein RecR K06187 recR; recombination protein RecR
E Tgr7_0968 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Tgr7_2235 DNA recombination protein, RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Tgr7_2234 Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Tgr7_2236 Crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E Tgr7_2124 UvrD/REP helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E Tgr7_1280 DNA helicase/exodeoxyribonuclease V, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E Tgr7_2433 CRISPR-associated Cas1/Cas4 family protein K15342 cas1; CRISP-associated protein Cas1
E Tgr7_1800 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Tgr7_1535 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Tgr7_0004 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Tgr7_0191 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Tgr7_0942 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Tgr7_1460 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Tgr7_1094 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Tgr7_1075 recombination protein RecR K06187 recR; recombination protein RecR
F Tgr7_2024 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F Tgr7_0362 Factor for inversion stimulation Fis transcriptional activator-like protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F Tgr7_1456 integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F Tgr7_1544 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F Tgr7_1931 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Tgr7_2295 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F Tgr7_1444 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F Tgr7_1759 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Tgr7_3073 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D Tgr7_1287 recA protein K03553 recA; recombination protein RecA
D Tgr7_3074 Repressor lexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D Tgr7_3151 Repressor lexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D Tgr7_0968 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Tgr7_2293 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Tgr7_2820 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein
D Tgr7_1288 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Tgr7_0626 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D Tgr7_1409 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Tgr7_0156 DEAD/DEAH box helicase domain-containing protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Tgr7_0883 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Tgr7_0781 mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Tgr7_0103 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Tgr7_2615 Ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Tgr7_2673 Ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Tgr7_2614 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024