+F Repair protein KO
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DNA Repair and Recombination Proteins - Thiomonas arsenitoxydans
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D THI_0786 ogt; Methylated-DNA--protein-cysteine methyltransferase (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D THI_1893 putative methylated-DNA-[protein]-cysteine S-methyltransferase (ogt) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D THI_1164 putative Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D THI_1166 putative Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D THI_2944 putative Deoxyribodipyrimidine photo-lyase PhrB K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E THI_0377 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E THI_1901 nth; Endonuclease III (DNA-(apurinic or apyrimidinic site) lyase) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D THI_0413 putative NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D THI_1020 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (dUTP pyrophosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D THI_0786 ogt; Methylated-DNA--protein-cysteine methyltransferase (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D THI_1893 putative methylated-DNA-[protein]-cysteine S-methyltransferase (ogt) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D THI_1164 putative Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D THI_1166 putative Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D THI_2944 putative Deoxyribodipyrimidine photo-lyase PhrB K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D THI_1165 putative Deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E THI_0665 putative Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E THI_1399 putative Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E THI_0445 putative DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E THI_0785 putative protein fused Methylated-DNA--[protein]-cysteine S-methyltransferase and DNA-3-methyladenine glycosylase II K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E THI_0377 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E THI_0379 mutM; Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (AP lyase mutM) K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E THI_1901 nth; Endonuclease III (DNA-(apurinic or apyrimidinic site) lyase) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E THI_1819 putative exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E THI_1650 putative Nuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E THI_1145 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E THI_1898 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E THI_1572 polA; DNA polymerase I (POL I) K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E THI_0089 uvrA; UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A) K03701 uvrA; excinuclease ABC subunit A
E THI_1757 Putative Excinuclease and ABC-type transport system, ATPase component K03701 uvrA; excinuclease ABC subunit A
E THI_2280 uvrB; UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B) K03702 uvrB; excinuclease ABC subunit B
E THI_1400 putative UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C) K03703 uvrC; excinuclease ABC subunit C
E THI_1295 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E THI_1572 polA; DNA polymerase I (POL I) K02335 polA; DNA polymerase I [EC:2.7.7.7]
E THI_1898 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F THI_3719 rpoB; DNA-directed RNA polymerase beta chain (RNAP beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F THI_3718 rpoC; DNA-directed RNA polymerase beta' chain (RNAP beta' subunit) (Transcriptase beta' chain) (RNA polymerase beta' subunit) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F THI_3012 rpoA; DNA-directed RNA polymerase alpha chain (RNAP alpha subunit) (Transcriptase alpha chain) (RNA polymerase alpha subunit) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F THI_3194 putative DNA-directed RNA polymerase omega chain (RNAP omega subunit) (Transcriptase omega chain) (RNA polymerase omega subunit) K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F THI_2109 mfd; Transcription-repair coupling factor (TRCF) (ATP-dependent helicase mfd) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E THI_1796 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E THI_2129 Putative Mismatch repair ATPase (MutS family) K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E THI_1564 putative DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E THI_2101 xseA; Exodeoxyribonuclease 7 large subunit (Exodeoxyribonuclease VII large subunit) (Exonuclease VII large subunit) K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E THI_1787 xseB; Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E THI_2829 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E THI_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E THI_2980 putative DNA polymerase III chi subunit, HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E THI_0168 putative DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E THI_1879 putative DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E THI_1346 putative protein fusion of DNA polymerase III, epsilon subunit and Excinuclease ABC, C subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E THI_1689 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E THI_2291 putative DNA polymerase III subunit tau [Contains: DNA polymerase III subunit gamma] (DnaX) K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E THI_1898 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E THI_1295 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E THI_0087 ssb; Single-stranded DNA-binding protein (SSB) (Helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein
E THI_p0033 ssb; Single-stranded DNA-binding protein (SSB) (Helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein
E THI_0080 ecoRVM; Modification methylase EcoRV (Adenine-specific methyltransferase EcoRV) (M.EcoRV) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E THI_3190 putative exodeoxyribonuclease V, beta subunit recB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E THI_3189 putative exodeoxyribonuclease V, gamma subunit recC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E THI_3191 putative exodeoxyribonuclease V, alpha subunit recD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E THI_1042 recA; Protein recA (Recombinase A) K03553 recA; recombination protein RecA
E THI_3250 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E THI_0264 ruvB; Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E THI_3259 ruvC; Crossover junction endodeoxyribonuclease ruvC (Holliday junction nuclease ruvC) (Holliday juction resolvase ruvC) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E THI_3746 putative Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E THI_2450 putative Primosomal replication protein n (PriB) K02686 priB; primosomal replication protein N
D RecFOR pathway proteins
E THI_1042 recA; Protein recA (Recombinase A) K03553 recA; recombination protein RecA
E THI_0772 radA; DNA repair protein radA (DNA repair protein sms) K04485 radA; DNA repair protein RadA/Sms
E THI_0862 recG; ATP-dependent DNA helicase recG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E THI_1145 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E THI_2767 putative DNA repair protein recO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
E THI_2289 recR; Recombination protein recR K06187 recR; recombination protein RecR
E THI_3384 putative DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E THI_3250 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E THI_0264 ruvB; Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E THI_3259 ruvC; Crossover junction endodeoxyribonuclease ruvC (Holliday junction nuclease ruvC) (Holliday juction resolvase ruvC) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E THI_1134 putative ATPase,yjgR K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F THI_2307 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F THI_0003 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F THI_1423 hupB; DNA-binding protein HU-beta (NS1) (HU-1) K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F THI_1145 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F THI_2767 putative DNA repair protein recO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
F THI_2289 recR; Recombination protein recR K06187 recR; recombination protein RecR
F THI_1898 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F THI_3261 putative DNA-binding protein fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F THI_1705 ihfA; integration host factor (IHF), alpha subunit K04764 ihfA; integration host factor subunit alpha
F THI_2373 putative Integration host factor (IHF) K05788 ihfB; integration host factor subunit beta
F THI_2300 himD; Integration host factor subunit beta (IHF-beta) K05788 ihfB; integration host factor subunit beta
E Supressor
F THI_2517 recQ; ATP-dependent DNA helicase recQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F THI_0089 uvrA; UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A) K03701 uvrA; excinuclease ABC subunit A
F THI_1757 Putative Excinuclease and ABC-type transport system, ATPase component K03701 uvrA; excinuclease ABC subunit A
F THI_2280 uvrB; UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B) K03702 uvrB; excinuclease ABC subunit B
F THI_1086 putative Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
F THI_p0018 putative Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D THI_0789 putative DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D THI_1042 recA; Protein recA (Recombinase A) K03553 recA; recombination protein RecA
D THI_1566 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D THI_3384 putative DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D THI_0946 putative RecA/RadA recombinase K14160 imuA; protein ImuA
D THI_0945 Putative DNA polymerase K14161 imuB; protein ImuB
D THI_0944 dnaE2; Error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D THI_0087 ssb; Single-stranded DNA-binding protein (SSB) (Helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein
D THI_p0033 ssb; Single-stranded DNA-binding protein (SSB) (Helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein
D THI_1043 recX; regulatory protein recX family K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D THI_2918 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D THI_1634 putative DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D THI_0598 putative ATP-dependent RNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D THI_0413 putative NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D THI_1020 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (dUTP pyrophosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D THI_0572 Putative Ribonucleoside-diphosphate reductase large chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D THI_0648 putative Ribonucleoside-diphosphate reductase (ribonucleoside diphosphate reductase, alpha subunit) (Ribonucleotide reductase large subunit) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D THI_0650 putative Ribonucleoside-diphosphate reductase (ribonucleoside diphosphate reductase, beta subunit) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024