+D Messenger RNA Biogenesis KO
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Prokaryotic Defense System - Thiocapsa sp. M50B4
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ACRISPR-Cas system
B Universal Cas proteins
B Type I CRISPR-Cas system
C Type I signiture cas proteins
C Subtype I-A factors
C Subtype I-B factors
C Subtype I-C factors
C Subtype I-D factors
C Subtype I-E factors
C Subtype I-F factors
C Subtype I-U factors
B Type II CRISPR-Cas system
C Type II signiture cas proteins
C Subtype II-A factors
C Subtype II-B factors
B Type III CRISPR-Cas system
C Type III signiture cas proteins
C Subtype III-A factors
C Subtype III-B factors
C Subtype III-U factors
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ARestriction and modification system (R-M system)
B Type I R-M system
C KFB96_25225 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C KFB96_08195 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C KFB96_08325 DEAD/DEAH box helicase family protein K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C KFB96_08935 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C KFB96_03765 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C KFB96_08210 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C KFB96_08345 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C KFB96_11245 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C KFB96_24450 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C KFB96_08220 type I restriction-modification system subunit M K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C KFB96_20575 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
B Type II R-M system
C Restriction endonucleases
C DNA methyltransferases
D KFB96_25470 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D KFB96_14990 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Type III R-M system
C KFB96_14730 DEAD/DEAH box helicase family protein K01156 res; type III restriction enzyme [EC:3.1.21.5]
C KFB96_22510 DEAD/DEAH box helicase family protein K01156 res; type III restriction enzyme [EC:3.1.21.5]
C KFB96_14735 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
C KFB96_22535 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
B Type IV R-M system
C KFB96_22915 hypothetical protein K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C KFB96_00620 restriction endonuclease K07448 mrr; restriction system protein
C KFB96_21995 restriction endonuclease K07448 mrr; restriction system protein
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AToxin-antitoxin system (TA system)
B Type I TA system
C Hok-Sok
C SymE-SymR
C Ldr-Rdl
C TisB-IstR
C Ibs-Sib
C ShoB-OhsC
C RalR-RalA
B Type II TA system
C MazF-MazE
D KFB96_24640 type II toxin-antitoxin system PemK/MazF family toxin K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D KFB96_03945 type II toxin-antitoxin system PemK/MazF family toxin K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D KFB96_09360 mazF; endoribonuclease MazF K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D KFB96_11660 type II toxin-antitoxin system PemK/MazF family toxin K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D KFB96_24635 hypothetical protein K07172 mazE; antitoxin MazE
D KFB96_03755 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K07172 mazE; antitoxin MazE
D KFB96_03940 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K07172 mazE; antitoxin MazE
D KFB96_09365 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K07172 mazE; antitoxin MazE
C ChpB-ChpS
D KFB96_10180 type II toxin-antitoxin system PemK/MazF family toxin K18841 chpB; mRNA interferase ChpB [EC:3.1.-.-]
D KFB96_12220 type II toxin-antitoxin system PemK/MazF family toxin K18841 chpB; mRNA interferase ChpB [EC:3.1.-.-]
D KFB96_10190 antitoxin K18842 chpS; antitoxin ChpS
D KFB96_12225 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K18842 chpS; antitoxin ChpS
C YhaV-PrlF
D KFB96_10480 type II toxin-antitoxin system YhaV family toxin K19155 yhaV; toxin YhaV [EC:3.1.-.-]
D KFB96_16335 type II toxin-antitoxin system YhaV family toxin K19155 yhaV; toxin YhaV [EC:3.1.-.-]
D KFB96_16340 type II toxin-antitoxin system PrlF family antitoxin K19156 prlF; antitoxin PrlF
C RelE/StbE-RelB/StbD
D KFB96_24550 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE
D KFB96_24970 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE
D KFB96_01035 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE
D KFB96_01615 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE
D KFB96_05810 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE
D KFB96_10845 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE
D KFB96_24545 hypothetical protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D KFB96_05805 type II toxin-antitoxin system prevent-host-death family antitoxin K18923 stbD; antitoxin StbD
D KFB96_12570 type II toxin-antitoxin system prevent-host-death family antitoxin K18923 stbD; antitoxin StbD
C YafQ-dinJ
D KFB96_24625 type II toxin-antitoxin system YafQ family toxin K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-]
D KFB96_04510 type II toxin-antitoxin system YafQ family toxin K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-]
D KFB96_20270 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-]
D KFB96_24620 type II toxin-antitoxin system RelB/DinJ family antitoxin K07473 dinJ; DNA-damage-inducible protein J
D KFB96_00545 type II toxin-antitoxin system RelB/DinJ family antitoxin K07473 dinJ; DNA-damage-inducible protein J
C YoeB-YefM
D KFB96_09180 Txe/YoeB family addiction module toxin K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D KFB96_12195 Txe/YoeB family addiction module toxin K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D KFB96_10865 type II toxin-antitoxin system prevent-host-death family antitoxin K19159 yefM; antitoxin YefM
D KFB96_12190 type II toxin-antitoxin system Phd/YefM family antitoxin K19159 yefM; antitoxin YefM
D KFB96_14045 type II toxin-antitoxin system Phd/YefM family antitoxin K19159 yefM; antitoxin YefM
C HipA-HipB
C HicA-HicB
D KFB96_06735 type II toxin-antitoxin system HicA family toxin K07339 hicA; mRNA interferase HicA [EC:3.1.-.-]
D KFB96_01965 type II toxin-antitoxin system HicB family antitoxin K18843 hicB; antitoxin HicB
C YafO-YafN
C Hha-TomB
C PspC-PspB
C CcdB-CcdA
C ParE-ParD
D KFB96_04165 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_05820 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_06035 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_07995 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_10025 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_12255 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_18530 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_18720 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_19380 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_22580 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D KFB96_04100 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D KFB96_10030 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D KFB96_12250 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D KFB96_14605 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D KFB96_18525 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D KFB96_18715 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D KFB96_22585 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
C Doc-Phd
D KFB96_20535 type II toxin-antitoxin system Phd/YefM family antitoxin K19165 phd; antitoxin Phd
C HigB-HigA
D KFB96_03375 type II toxin-antitoxin system HigB family toxin K19166 higB; mRNA interferase HigB [EC:3.1.-.-]
D KFB96_08330 type II toxin-antitoxin system HigB family toxin K19166 higB; mRNA interferase HigB [EC:3.1.-.-]
D KFB96_25615 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_02020 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_02555 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_04705 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_04825 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_04840 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_04930 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_07215 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_09590 type II toxin-antitoxin system RelE/ParE family toxin K07334 higB-1; toxin HigB-1
D KFB96_03370 transcriptional regulator K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D KFB96_08335 ImmA/IrrE family metallo-endopeptidase K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D KFB96_16520 transcriptional regulator K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D KFB96_25620 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_00525 helix-turn-helix domain-containing protein K21498 higA-1; antitoxin HigA-1
D KFB96_02025 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_02550 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_04710 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_04820 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_04845 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_04935 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_07075 helix-turn-helix domain-containing protein K21498 higA-1; antitoxin HigA-1
D KFB96_07220 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D KFB96_09585 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
C MqsR-MqsA
D KFB96_06155 type II toxin-antitoxin system MqsR family toxin K13651 mqsR; motility quorum-sensing regulator / GCU-specific mRNA interferase toxin
D KFB96_06150 type II toxin-antitoxin system MqsA family antitoxin K13655 mqsA; HTH-type transcriptional regulator / antitoxin MqsA
D KFB96_10250 type II toxin-antitoxin system MqsA family antitoxin K13655 mqsA; HTH-type transcriptional regulator / antitoxin MqsA
C VapC-VapB
D KFB96_24650 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D KFB96_25820 PIN domain-containing protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D KFB96_00145 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D KFB96_04960 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D KFB96_09460 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D KFB96_17955 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D KFB96_20290 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D KFB96_25825 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K18829 mvpT; antitoxin VapB
D KFB96_00140 antitoxin K18829 mvpT; antitoxin VapB
D KFB96_17960 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K18829 mvpT; antitoxin VapB
D KFB96_24810 type II toxin-antitoxin system VapC family toxin K19686 vapC; ribonuclease VapC [EC:3.1.-.-]
D KFB96_20250 type II toxin-antitoxin system VapC family toxin K19686 vapC; ribonuclease VapC [EC:3.1.-.-]
D KFB96_21405 type II toxin-antitoxin system VapC family toxin K19686 vapC; ribonuclease VapC [EC:3.1.-.-]
D KFB96_24815 hypothetical protein K19687 vapB; antitoxin VapB
D KFB96_20255 type II toxin-antitoxin system VapB family antitoxin K19687 vapB; antitoxin VapB
D KFB96_21400 type II toxin-antitoxin system VapB family antitoxin K19687 vapB; antitoxin VapB
C PezT-PezA
C YobL-YobK
C YokI-YokJ
C YqcG-YqcF
C YxiD-YxxD
C FitB-FitA
D KFB96_03130 type II toxin-antitoxin system VapC family toxin K07062 fitB; toxin FitB [EC:3.1.-.-]
D KFB96_20540 type II toxin-antitoxin system VapC family toxin K07062 fitB; toxin FitB [EC:3.1.-.-]
D KFB96_21930 type II toxin-antitoxin system VapC family toxin K07062 fitB; toxin FitB [EC:3.1.-.-]
D KFB96_22785 type II toxin-antitoxin system VapC family toxin K07062 fitB; toxin FitB [EC:3.1.-.-]
D KFB96_15005 plasmid stabilization protein K21495 fitA; antitoxin FitA
D KFB96_15705 DNA-binding protein K21495 fitA; antitoxin FitA
C BC_0920-BC_0921
C Type II TA system related factors
D KFB96_13670 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D KFB96_16450 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D KFB96_00155 parC; DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D KFB96_25305 parE; DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D KFB96_25405 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
B Type III TA system
C AbiQ system
B Type IV TA system
C YeeV-YeeU
C CptA-CptB
D KFB96_09195 hypothetical protein K19168 cptA; toxin CptA
D KFB96_09205 succinate dehydrogenase assembly factor 2 K09159 cptB; antitoxin CptB
B Type V TA system
C GhoT-GhoS
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ADNA phosphothiolation system
B Sulfur modification proteins
C KFB96_04500 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KFB96_08110 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
B DNA phosphorothioation-dependent restriction proteins
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 7, 2023