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Transfer RNA Biogenesis - Candidatus Thiothrix singaporensis
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D HZT40_19420 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D HZT40_12100 ribonuclease K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D HZT40_00245 multifunctional CCA addition/repair protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D HZT40_21120 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D HZT40_19280 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D HZT40_05895 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D HZT40_08255 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D HZT40_15485 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D HZT40_07025 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D HZT40_05165 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D HZT40_08190 glutamine--tRNA ligase/YqeY domain fusion protein K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D HZT40_23050 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HZT40_00035 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HZT40_03985 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D HZT40_06855 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D HZT40_21535 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D HZT40_09840 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D HZT40_09395 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D HZT40_08475 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D HZT40_13145 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D HZT40_09705 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D HZT40_08015 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D HZT40_09375 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D HZT40_09370 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D HZT40_02240 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D HZT40_04900 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
C AARS associated factors
D HZT40_16840 histidine triad nucleotide-binding protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D HZT40_20205 trmB; tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D HZT40_00300 tsaA; tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D HZT40_12935 tsaA; tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D HZT40_16700 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D HZT40_16295 truB; tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D HZT40_15730 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D HZT40_02200 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HZT40_08820 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D HZT40_21560 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D HZT40_15500 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D HZT40_18745 mnmE; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D HZT40_00555 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D HZT40_13790 selD; selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D HZT40_21135 guanylyltransferase K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D HZT40_15370 cysQ; 3'(2'),5'-bisphosphate nucleotidase CysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D HZT40_18755 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D HZT40_19420 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D HZT40_07380 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D HZT40_15550 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D HZT40_19225 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D HZT40_12100 ribonuclease K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D HZT40_00245 multifunctional CCA addition/repair protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D HZT40_21120 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D HZT40_19280 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D HZT40_17990 RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
D HZT40_18540 RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D HZT40_13590 ettA; energy-dependent translational throttle protein EttA K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D HZT40_07025 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D HZT40_08255 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D HZT40_02240 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D HZT40_04900 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D HZT40_09395 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D HZT40_15485 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D HZT40_03985 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D HZT40_21535 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D HZT40_09840 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D HZT40_09705 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D HZT40_05165 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D HZT40_08475 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D HZT40_06855 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D HZT40_13145 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D HZT40_05895 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D HZT40_08190 glutamine--tRNA ligase/YqeY domain fusion protein K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D HZT40_23050 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HZT40_00035 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HZT40_09375 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D HZT40_09370 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D HZT40_08015 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D HZT40_05280 gluQRS; tRNA glutamyl-Q(34) synthetase GluQRS K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D HZT40_05885 ybaK; Cys-tRNA(Pro) deacylase K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
D HZT40_23015 dusA; tRNA dihydrouridine(20/20a) synthase DusA K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D HZT40_05125 dusB; tRNA dihydrouridine synthase DusB K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D HZT40_18975 tRNA-dihydrouridine synthase K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D HZT40_06575 miaB; tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D HZT40_02110 mtaB; tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase MtaB K18707 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB [EC:2.8.4.5]
C Methyltransferases
D HZT40_08115 cmoA; carboxy-S-adenosyl-L-methionine synthase CmoA K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D HZT40_08095 cmoB; tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D HZT40_19265 methyltransferase domain-containing protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D HZT40_20205 trmB; tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D HZT40_11645 trmD; tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D HZT40_18745 mnmE; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D HZT40_13075 RNA methyltransferase K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D HZT40_00300 tsaA; tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D HZT40_12935 tsaA; tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D HZT40_16700 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D HZT40_16295 truB; tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D HZT40_15310 truC; tRNA pseudouridine(65) synthase TruC K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D HZT40_15730 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D HZT40_13215 RNA pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D HZT40_19200 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D HZT40_06735 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D HZT40_15975 tRNA 2-thiocytidine biosynthesis protein TtcA K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D HZT40_15720 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D HZT40_16485 dsrH; sulfurtransferase complex subunit TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D HZT40_16490 tusC; sulfurtransferase complex subunit TusC K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D HZT40_16495 tusD; sulfurtransferase complex subunit TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D HZT40_10375 TusE/DsrC/DsvC family sulfur relay protein K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D HZT40_10955 TusE/DsrC/DsvC family sulfur relay protein K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D HZT40_02210 iscA; iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D HZT40_08830 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein
D HZT40_02200 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HZT40_08820 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HZT40_08600 folate-binding protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D HZT40_00555 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D HZT40_15500 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D HZT40_10115 mnmC; bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D HZT40_03740 queA; tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D HZT40_06415 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D HZT40_06410 6-carboxytetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D HZT40_14040 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase QueF K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D HZT40_13790 selD; selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D HZT40_13795 mnmH; tRNA 2-selenouridine(34) synthase MnmH K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D HZT40_21505 tgt; tRNA guanosine(34) transglycosylase Tgt K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D HZT40_04855 tilS; tRNA lysidine(34) synthetase TilS K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D HZT40_21560 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D HZT40_05560 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D HZT40_21545 tsaE; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D HZT40_09950 tRNA threonylcarbamoyladenosine dehydratase K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C HZT40_04920 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C HZT40_18530 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
C HZT40_02770 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
C HZT40_06450 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024