+F Repair protein KO
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DNA Repair and Recombination Proteins - Candidatus Thiothrix singaporensis
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HZT40_21100 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E HZT40_12505 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HZT40_22775 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HZT40_04455 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
E HZT40_04255 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
E HZT40_04255 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
D HZT40_04255 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D HZT40_11710 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HZT40_06545 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HZT40_21100 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D HZT40_21090 alkB; DNA oxidative demethylase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E HZT40_12505 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HZT40_03890 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E HZT40_22775 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HZT40_15915 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E HZT40_23005 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E HZT40_04455 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E HZT40_17090 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E HZT40_18795 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
D DNA ligase
E HZT40_06070 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E HZT40_20020 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E HZT40_09760 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E HZT40_08425 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E HZT40_05630 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E HZT40_20095 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HZT40_20020 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E HZT40_06070 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F HZT40_00385 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F HZT40_00535 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F HZT40_17530 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F HZT40_11955 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E HZT40_08050 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E HZT40_15495 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
E HZT40_05805 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E HZT40_09695 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E HZT40_05330 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E HZT40_06820 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E HZT40_17535 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HZT40_02170 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HZT40_10840 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D DNA ligase
E HZT40_06070 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E HZT40_20095 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HZT40_06565 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E HZT40_11335 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E HZT40_19475 vsr; DNA mismatch endonuclease Vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E HZT40_04415 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E HZT40_13460 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E HZT40_06245 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E HZT40_09850 recA; recombinase RecA K03553 recA; recombination protein RecA
E HZT40_22605 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HZT40_21885 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E HZT40_21840 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E HZT40_10845 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E HZT40_10850 exonuclease SbcCD subunit D C-terminal domain-containing protein K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E HZT40_09850 recA; recombinase RecA K03553 recA; recombination protein RecA
E HZT40_11695 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E HZT40_18775 AAA family ATPase K03629 recF; DNA replication and repair protein RecF
E HZT40_18780 hypothetical protein K03629 recF; DNA replication and repair protein RecF
E HZT40_22285 putative DNA binding domain-containing protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E HZT40_08615 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E HZT40_06030 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E HZT40_16860 recR; recombination protein RecR K06187 recR; recombination protein RecR
E HZT40_06090 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E HZT40_05155 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E HZT40_22605 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HZT40_21885 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E HZT40_01895 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E HZT40_02750 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E HZT40_02785 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E HZT40_10845 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E HZT40_10850 exonuclease SbcCD subunit D C-terminal domain-containing protein K03547 sbcD; DNA repair protein SbcD/Mre11
E HZT40_05320 DUF853 family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F HZT40_06665 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F HZT40_18785 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F HZT40_21565 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F HZT40_02080 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F HZT40_06030 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F HZT40_16860 recR; recombination protein RecR K06187 recR; recombination protein RecR
F HZT40_06070 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F HZT40_09295 Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F HZT40_06715 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F HZT40_13340 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F HZT40_09760 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F HZT40_08425 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F HZT40_13170 H-NS histone family protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D HZT40_10750 Y-family DNA polymerase K03502 umuC; DNA polymerase V
D HZT40_10755 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D HZT40_09850 recA; recombinase RecA K03553 recA; recombination protein RecA
D HZT40_18730 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D HZT40_06090 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D HZT40_06565 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D HZT40_11335 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D HZT40_12740 dinD; DNA damage-inducible protein D K14623 dinD; DNA-damage-inducible protein D
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D HZT40_05055 rep; DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D HZT40_01205 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D HZT40_11710 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HZT40_06545 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D HZT40_17775 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D HZT40_17770 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024