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Transfer RNA Biogenesis - Thermoflexus hugenholtzii
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D KNN16_12995 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D KNN16_14795 CBS domain-containing protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D KNN16_12750 intein-containing RctB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D KNN16_12755 archease K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D KNN16_13585 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D KNN16_13565 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D KNN16_12375 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D KNN16_01150 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D KNN16_14415 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D KNN16_09455 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D KNN16_11775 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KNN16_03750 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D KNN16_09145 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KNN16_13775 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KNN16_11320 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D KNN16_11685 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D KNN16_07705 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D KNN16_02950 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D KNN16_03090 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D KNN16_07360 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D KNN16_02390 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D KNN16_02380 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D KNN16_13025 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D KNN16_12420 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D KNN16_12645 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D KNN16_12380 alanyl-tRNA editing protein K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D KNN16_04420 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D KNN16_05540 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D KNN16_15020 tRNA (adenine-N1)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D KNN16_08595 trmB; tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
C Psudouridine synthases
D KNN16_00765 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D KNN16_10120 truB; tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D KNN16_11760 tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D KNN16_08970 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D KNN16_09905 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D KNN16_06925 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D KNN16_12760 selD; selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D KNN16_07000 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D KNN16_12995 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D KNN16_13100 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
C CCA adding factors
D KNN16_14795 CBS domain-containing protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D KNN16_12750 intein-containing RctB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D KNN16_09805 thpR; RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D KNN16_01150 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D KNN16_13565 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D KNN16_13025 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D KNN16_12420 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D KNN16_11685 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D KNN16_12375 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D KNN16_11775 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KNN16_09145 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KNN16_13775 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KNN16_03090 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D KNN16_14415 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D KNN16_07705 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D KNN16_03750 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D KNN16_10665 glyS; glycine--tRNA ligase subunit beta K14164 glyQS; glycyl-tRNA synthetase [EC:6.1.1.14]
D KNN16_02950 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D KNN16_13585 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D KNN16_09455 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D KNN16_02390 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D KNN16_02380 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D KNN16_07360 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D KNN16_11320 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D KNN16_12645 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D KNN16_12380 alanyl-tRNA editing protein K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
D KNN16_06800 miaB; tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D KNN16_07140 trmFO; methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D KNN16_08595 trmB; tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D KNN16_09950 trmD; tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D KNN16_14405 RNA methyltransferase K03437 spoU; RNA methyltransferase, TrmH family
C Psudouridine synthases
D KNN16_00765 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D KNN16_10120 truB; tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D KNN16_11760 tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D KNN16_08955 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D KNN16_05655 TIGR00269 family protein K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
D KNN16_05190 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D KNN16_08970 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Other tRNA modification factors
D KNN16_06925 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D KNN16_01265 queA; tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D KNN16_06740 6-pyruvoyl tetrahydropterin synthase family protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D KNN16_07650 queF; preQ(1) synthase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D KNN16_14595 queG; tRNA epoxyqueuosine(34) reductase QueG K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D KNN16_12760 selD; selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D KNN16_02560 tgt; tRNA guanosine(34) transglycosylase Tgt K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D KNN16_11225 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D KNN16_06250 tilS; tRNA lysidine(34) synthetase TilS K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D KNN16_13940 tsaB; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D KNN16_09905 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D KNN16_14915 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D KNN16_13945 tsaE; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
B tRNA degradation factors
C KNN16_07165 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024