+C Two-component system KO
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Two-Component System - Thioploca ingrica
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C THII_3033 phosphate regulon sensor kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C THII_3034 chemotaxis protein CheY K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
C THII_3449 chemotaxis protein CheY K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
C THII_1625 histidine kinase K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
C THII_1624 transcriptional regulator K07664 baeR; two-component system, OmpR family, response regulator BaeR
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C THII_1571 osmosensitive K channel His kinase sensor K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C THII_1570 transcriptional regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C THII_3062 sensor kinase protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C THII_2406 chemotaxis protein CheY K02483 K02483; two-component system, OmpR family, response regulator
C THII_3063 response regulator receiver:transcriptional regulatory protein, C-terminal K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C THII_0943 regulatory protein LuxR K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C THII_0687 putative regulator of cell autolysis K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
C THII_0686 hypothetical protein K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B BtsS-BtsR (pyruvate reutilization)
B PyrS-PyrR (pyruvate reutilization)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
C THII_2580 signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C THII_2581 sigma-54 dependent DNA-binding response regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
C THII_1122 response regulator HsfA K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
C THII_0492 two component, sigma54 specific, transcriptional regulator, Fis family protein K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
C THII_2753 histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C THII_2752 chemotaxis protein CheY K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
C THII_2981 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 glrR; two-component system, NtrC family, response regulator GlrR
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
C THII_0592 formyl transferase domain-containing protein K19640 hypX; putative two-component system protein, hydrogenase maturation factor HypX/HoxX
B Unclassified
C THII_1121 sensory transduction protein kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C THII_1585 two-component sensor histidine kinase protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C THII_0554 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C THII_2177 chemotaxis protein histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C THII_0555 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C THII_2178 Fis family transcriptional regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C THII_2838 response regulator receiver K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C THII_0549 chemotaxis-specific methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C THII_2295 CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C THII_2442 response regulator receiver protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
C THII_1283 chemotaxis protein histidine kinase-like protein K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C THII_1288 pilus response regulator PilG K02657 pilG; twitching motility two-component system response regulator PilG
C THII_2699 pilus response regulator PilG K02657 pilG; twitching motility two-component system response regulator PilG
C THII_1287 chemotaxis protein CheY K02658 pilH; twitching motility two-component system response regulator PilH
C THII_1984 chemotaxis protein CheY K02658 pilH; twitching motility two-component system response regulator PilH
C THII_2085 chemotaxis protein CheY K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
C THII_1928 response regulator receiver domain protein K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
C THII_1929 response regulator receiver modulated CheB methylesterase K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
C THII_0540 response regulator receiver protein K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C THII_2582 signal transduction histidine kinase K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
C THII_0051 multi-sensor hybrid histidine kinase K20976 hptB; histidine phosphotransfer protein HptB
B PdtaS-PdtaR
B NasS-NasT
C THII_1784 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component K22067 nasS; two-component system, oxyanion-binding sensor
C THII_1785 chemotaxis protein CheY K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
C THII_0070 signal transduction histidine kinase K19694 chiS; two-component system, sensor histidine kinase ChiS
C THII_0443 response regulator receiver protein K19694 chiS; two-component system, sensor histidine kinase ChiS
C THII_2325 sensory box sensor histidine kinase/response regulator K19694 chiS; two-component system, sensor histidine kinase ChiS
C THII_0775 response regulator receiver protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C THII_0919 histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C THII_1130 response regulator receiver modulated metal dependent phosphohydrolase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C THII_1366 response regulator receiver protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C THII_3415 histidine kinase-like protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C THII_3833 response regulator receiver protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 8, 2024