+F Repair protein KO
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DNA Repair and Recombination Proteins - Treponema phagedenis
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D FUT81_09595 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E FUT81_03630 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E FUT81_02810 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
E FUT81_15305 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E FUT81_08545 DEAD/DEAH box helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D FUT81_06725 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D FUT81_04985 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D FUT81_03440 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D FUT81_09595 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E FUT81_07815 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E FUT81_03630 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E FUT81_02810 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E FUT81_00770 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E FUT81_07000 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E FUT81_15540 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E FUT81_14545 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E FUT81_15515 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E FUT81_03605 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E FUT81_07935 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E FUT81_13205 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E FUT81_15420 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E FUT81_14545 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E FUT81_15540 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F FUT81_08815 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F FUT81_08810 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F FUT81_14145 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F FUT81_09025 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F FUT81_04105 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E FUT81_09425 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E FUT81_05610 endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E FUT81_13810 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E FUT81_12265 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E FUT81_13710 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E FUT81_05890 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E FUT81_00010 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E FUT81_06455 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E FUT81_06615 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E FUT81_03930 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E FUT81_07100 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E FUT81_13280 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E FUT81_05485 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E FUT81_15540 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E FUT81_13205 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E FUT81_15420 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E FUT81_07070 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E FUT81_03960 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E FUT81_11060 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E FUT81_04865 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E FUT81_02220 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_02485 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_07310 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_03220 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_11055 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_00630 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_03635 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_08120 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E FUT81_15140 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E FUT81_08955 recA; recombinase RecA K03553 recA; recombination protein RecA
E FUT81_01125 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E FUT81_12235 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E FUT81_01070 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E FUT81_00385 sbcC; exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E FUT81_00380 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E FUT81_08955 recA; recombinase RecA K03553 recA; recombination protein RecA
E FUT81_12375 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E FUT81_00015 DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E FUT81_03280 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E FUT81_07000 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E FUT81_13270 recR; recombination protein RecR K06187 recR; recombination protein RecR
E FUT81_09535 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E FUT81_01125 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E FUT81_12235 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E FUT81_01070 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E FUT81_00385 sbcC; exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E FUT81_00380 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E FUT81_04405 DUF853 family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F FUT81_00040 gyrA; DNA topoisomerase (ATP-hydrolyzing) subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F FUT81_04610 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F FUT81_05130 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F FUT81_15335 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F FUT81_03935 recombination and repair protein RecT K07455 recT; recombination protein RecT
F FUT81_07095 recombination and repair protein RecT K07455 recT; recombination protein RecT
F FUT81_07000 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F FUT81_13270 recR; recombination protein RecR K06187 recR; recombination protein RecR
F FUT81_15540 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F FUT81_09355 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F FUT81_12075 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F FUT81_15515 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F FUT81_03605 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D FUT81_10010 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D FUT81_08955 recA; recombinase RecA K03553 recA; recombination protein RecA
D FUT81_02620 helix-turn-helix domain-containing protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D FUT81_03725 helix-turn-helix domain-containing protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D FUT81_09535 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D FUT81_07070 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D FUT81_03960 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D FUT81_11060 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D FUT81_04865 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D FUT81_09470 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D FUT81_11540 DEAD/DEAH box helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D FUT81_06725 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D FUT81_04985 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D FUT81_03440 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D FUT81_13665 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D FUT81_04185 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D FUT81_06260 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024