+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Ursus arctos (brown bear)
%
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 113245948 RNMT; mRNA cap guanine-N7 methyltransferase isoform X2 K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 113264837 RNGTT; mRNA-capping enzyme isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 113255256 CDK7; cyclin-dependent kinase 7 isoform X3 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 113252464 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 113263751 RAMAC; RNA guanine-N7 methyltransferase activating subunit K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 113260423 NCBP1; nuclear cap-binding protein subunit 1 isoform X1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 113241194 NCBP2L; nuclear cap-binding protein subunit 2-like K12883 NCBP2; nuclear cap-binding protein subunit 2
E 130541799 NCBP2; nuclear cap-binding protein subunit 2 isoform X1 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 113252258 NUDT21; cleavage and polyadenylation specificity factor subunit 5 isoform X2 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 113256292 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 113246928 CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform X2 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 113246377 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 113269383 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X2 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 113247604 CPSF1; cleavage and polyadenylation specificity factor subunit 1 isoform X2 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 113267347 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 113269703 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 113265149 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 113267910 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 113262495 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 113263491 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 113256946 WDR82; WD repeat-containing protein 82 isoform X2 K14962 WDR82; COMPASS component SWD2
E 113244033 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 113266966 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 113240761 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 113270626 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 isoform X2 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 113269525 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 3-like K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 113258748 CSTF1; cleavage stimulation factor subunit 1 isoform X1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 113258871 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 113244295 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 113265061 CSTF3; cleavage stimulation factor subunit 3 isoform X1 K14408 CSTF3; cleavage stimulation factor subunit 3
E 113243410 SYMPK; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 113258415 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X2 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 113247054 SNRPD3; small nuclear ribonucleoprotein Sm D3 isoform X1 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 113251677 small nuclear ribonucleoprotein E-like K11097 SNRPE; small nuclear ribonucleoprotein E
E 113258922 small nuclear ribonucleoprotein E-like K11097 SNRPE; small nuclear ribonucleoprotein E
E 113268732 small nuclear ribonucleoprotein F-like K11098 SNRPF; small nuclear ribonucleoprotein F
E 113256135 SNRPF; small nuclear ribonucleoprotein F isoform X1 K11098 SNRPF; small nuclear ribonucleoprotein F
E 113244230 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 113256336 small nuclear ribonucleoprotein G-like K11099 SNRPG; small nuclear ribonucleoprotein G
E 123001190 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein G-like K11099 SNRPG; small nuclear ribonucleoprotein G
E 123001237 small nuclear ribonucleoprotein G-like K11099 SNRPG; small nuclear ribonucleoprotein G
E 113268285 LSM10; U7 snRNA-associated Sm-like protein LSm10 isoform X1 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 113264025 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 113267347 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 113269703 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 113258871 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 113244295 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 113243410 SYMPK; symplekin K06100 SYMPK; symplekin
E 113245752 SLBP; histone RNA hairpin-binding protein isoform X1 K18710 SLBP; histone RNA hairpin-binding protein
E 113264820 CASP8AP2; CASP8-associated protein 2 isoform X1 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 113268874 SUPT4H1; transcription elongation factor SPT4 isoform X2 K15171 SUPT4H1; transcription elongation factor SPT4
E 113243587 SUPT5H; transcription elongation factor SPT5 isoform X2 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 113248480 METTL3; N6-adenosine-methyltransferase catalytic subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 113255602 METTL14; N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 113253257 METTL4; N(6)-adenine-specific methyltransferase METTL4 isoform X1 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 113269143 METTL16; RNA N6-adenosine-methyltransferase METTL16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 113259617 WTAP; pre-mRNA-splicing regulator WTAP isoform X1 K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 113252924 VIRMA; protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 113244907 RBM15; RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 113256925 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 113251346 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X6 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 113258531 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 113245323 PAPOLG; poly(A) polymerase gamma isoform X2 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 113267971 PAPOLB; poly(A) polymerase beta K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 113267289 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 113255167 TENT2; poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 113246966 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase isoform X1 K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 113250496 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 113251446 RBM26; RNA-binding protein 26 isoform X2 K13192 RBM26; RNA-binding protein 26
E 113252242 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 113271291 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 113270514 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 113268889 DHX40; probable ATP-dependent RNA helicase DHX40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 113241154 KIN; DNA/RNA-binding protein KIN17 K13102 KIN; DNA/RNA-binding protein KIN17
D 113250782 METTL8; tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 113270820 METTL22; methyltransferase-like protein 22 isoform X6 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 113261073 TENT5A; terminal nucleotidyltransferase 5A isoform X1 K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 113268444 TENT5B; terminal nucleotidyltransferase 5B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 113244369 TENT5C; terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 113242111 TENT5D; terminal nucleotidyltransferase 5D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 113267382 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X1 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 113267842 SRRT; serrate RNA effector molecule homolog isoform X3 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 113247764 RBM8A; RNA-binding protein 8A isoform X1 K12876 RBM8A; RNA-binding protein 8A
E 113257890 MAGOHB; protein mago nashi homolog 2 isoform X2 K12877 MAGOH; protein mago nashi
E 113254651 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 113244498 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 113243707 DDX39B; spliceosome RNA helicase DDX39B isoform X3 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 113244539 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 113257218 CCDC174; coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 113265496 CASC3; protein CASC3 K14323 CASC3; protein CASC3
E 113251176 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 113266156 PNN; pinin K13114 PNN; pinin
E 113246017 ACIN1; apoptotic chromatin condensation inducer in the nucleus isoform X1 K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 113245117 RNPS1; RNA-binding protein with serine-rich domain 1 isoform X1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 113268496 SRRM1; serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 113253264 THOC1; THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 113270925 THOC2; THO complex subunit 2 isoform X6 K12879 THOC2; THO complex subunit 2
E 113264118 THOC3; THO complex subunit 3 isoform X1 K12880 THOC3; THO complex subunit 3
E 113244498 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 113245015 THOC5; THO complex subunit 5 homolog isoform X1 K13174 THOC5; THO complex subunit 5
E 113245423 THOC6; THO complex subunit 6 homolog isoform X2 K13175 THOC6; THO complex subunit 6
E 113257038 THOC7; THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
E 113254092 LOW QUALITY PROTEIN: THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 113247586 PCID2; PCI domain-containing protein 2 isoform X1 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 113261105 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 113252815 ENY2; transcription and mRNA export factor ENY2 isoform X1 K11368 ENY2; enhancer of yellow 2 transcription factor
E 113246812 CETN2; centrin-2 isoform X1 K10840 CETN2; centrin-2
E 113255116 CETN3; centrin-3 K16466 CETN3; centrin-3
E 113255026 MCM3AP; germinal-center associated nuclear protein isoform X1 K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 113262755 TPR; nucleoprotein TPR isoform X3 K09291 TPR; nucleoprotein TPR
E 113258756 RAE1; mRNA export factor RAE1 K14298 RAE1; mRNA export factor
E 113257167 SEC13; protein SEC13 homolog isoform X1 K14004 SEC13; protein transport protein SEC13
E 113256081 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 113244639 NUP85; nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 113259549 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 113263251 NUP54; nucleoporin p54 K14308 NUP54; nuclear pore complex protein Nup54
E 113241228 NUP62CL; nucleoporin-62 C-terminal-like protein K14306 NUP62; nuclear pore complex protein Nup62
E 113243275 NUP62; nuclear pore glycoprotein p62 K14306 NUP62; nuclear pore complex protein Nup62
E 113271060 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 113252267 NUP93; nuclear pore complex protein Nup93 isoform X2 K14309 NUP93; nuclear pore complex protein Nup93
E 113269254 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X1 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 113256298 NUP107; nuclear pore complex protein Nup107 isoform X1 K14301 NUP107; nuclear pore complex protein Nup107
E 113259053 NUP133; nuclear pore complex protein Nup133 isoform X1 K14300 NUP133; nuclear pore complex protein Nup133
E 113266493 NUP188; nucleoporin NUP188 K14311 NUP188; nuclear pore complex protein Nup188
E 113264497 NUP153; nuclear pore complex protein Nup153 isoform X1 K14296 NUP153; nuclear pore complex protein Nup153
E 113260902 NUP155; nuclear pore complex protein Nup155 isoform X1 K14312 NUP155; nuclear pore complex protein Nup155
E 113250689 NUP35; nucleoporin NUP35 K14313 NUP35; nuclear pore complex protein Nup53
E 113264561 NUP205; nuclear pore complex protein Nup205 isoform X2 K14310 NUP205; nuclear pore complex protein Nup205
E 113257232 NUP210; nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 113245170 NUP210L; nuclear pore membrane glycoprotein 210-like K14314 NUP210; nuclear pore complex protein Nup210
E 113266528 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 113264250 POM121L2; POM121-like protein 2 K14316 POM121; nuclear pore complex protein Nup121
E 113267802 POM121C; nuclear envelope pore membrane protein POM 121C K14316 POM121; nuclear pore complex protein Nup121
E 113251191 NUP58; nucleoporin p58/p45 K14307 NUPL1; nucleoporin p58/p45
E 113261396 NUP42; nucleoporin NUP42 K14321 NUPL2; nucleoporin-like protein 2
E 113254647 NDC1; nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 113245939 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 113267793 E3 SUMO-protein ligase RanBP2 isoform X2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 113254024 SENP2; sentrin-specific protease 2 isoform X1 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 113255116 CETN3; centrin-3 K16466 CETN3; centrin-3
E 113266473 GLE1; mRNA export factor GLE1 K18723 GLE1; nucleoporin GLE1
E 113250092 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 113246935 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 125281258 nuclear RNA export factor 3-like K14284 NXF; nuclear RNA export factor
E 125281259 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 130544108 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 130544139 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 113241236 NXT2; NTF2-related export protein 2 K14285 NXT1_2; NTF2-related export protein 1/2
E 113246769 NXT1; NTF2-related export protein 1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 113266861 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 113240908 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X3 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 113260418 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 113271161 TNFSF13; tumor necrosis factor ligand superfamily member 13 isoform X1 K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13
E 113242911 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 113260567 ELAVL2; ELAV-like protein 2 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 113254693 ELAVL4; ELAV-like protein 4 isoform X2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 113264126 FAF2; FAS-associated factor 2 isoform X2 K18726 FAF2; FAS-associated factor 2
E 113260491 VCP; transitional endoplasmic reticulum ATPase isoform X1 K13525 VCP; transitional endoplasmic reticulum ATPase
E 113266206 VCPKMT; protein N-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 113247136 TNPO2; transportin-2 isoform X2 K18727 TNPO2; transportin-2
E 113245218 XPO1; exportin-1 isoform X1 K14290 XPO1; exportin-1
E 113270014 XPO7; exportin-7 K18460 XPO7; exportin-7
E 113264083 RANBP17; ran-binding protein 17 isoform X3 K24115 RANBP17; Ran-binding protein 17
E 113241735 RANGAP1; ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 113268952 TAF15; TATA-binding protein-associated factor 2N K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 113263893 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 113263123 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 113250342 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X2 K03259 EIF4E; translation initiation factor 4E
E 113253897 EIF4A2; eukaryotic initiation factor 4A-II isoform X1 K03257 EIF4A; translation initiation factor 4A
E 113271150 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 113268553 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 113248990 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 113254213 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 113248378 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4B-like K03258 EIF4B; translation initiation factor 4B
E 113267781 EIF4H; eukaryotic translation initiation factor 4H K24086 EIF4H; translation initiation factor 4H
E 113262099 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 113259142 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 113245060 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X3 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 113262684 ANGEL2; protein angel homolog 2 isoform X1 K18729 ANGEL; protein angel
E 113270304 ANGEL1; protein angel homolog 1 K18729 ANGEL; protein angel
E 113254657 FXR1; RNA-binding protein FXR1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 113241891 FMR1; fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 113271143 FXR2; RNA-binding protein FXR2 isoform X2 K15516 FMR; fragile X mental retardation protein
E 113263582 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 113264018 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 113264003 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 113245668 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 113243165 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113263742 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X9 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113266689 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113264113 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113248381 ATP-dependent RNA helicase DDX3X-like isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 113265882 DDX3X; ATP-dependent RNA helicase DDX3X isoform X2 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 113267848 GIGYF1; GRB10-interacting GYF protein 1 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 113250337 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 113242175 PABPC5; polyadenylate-binding protein 5 K13126 PABPC; polyadenylate-binding protein
E 113252872 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 113268249 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 113242138 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 113258643 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 113246576 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 113255673 PABPC4L; polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 125281205 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 113260958 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 113261802 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 113244155 PAIP2B; polyadenylate-binding protein-interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 113243737 SKIC2; SKI2 subunit of superkiller complex protein K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 113248806 DEAF1; LOW QUALITY PROTEIN: deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 113241121 malignant T-cell-amplified sequence 1-like K07575 MCTS; malignant T-cell-amplified sequence
E 113270913 MCTS1; malignant T-cell-amplified sequence 1 isoform X2 K07575 MCTS; malignant T-cell-amplified sequence
E 113266915 DENR; density-regulated protein isoform X2 K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 113258086 APOBEC1; C->U-editing enzyme APOBEC-1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 113258983 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 113256452 PYM1; partner of Y14 and mago isoform X1 K14294 WIBG; partner of Y14 and mago
E 113250731 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 113257520 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 113268852 MSI2; RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 113267038 MSI1; RNA-binding protein Musashi homolog 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 113242732 DAZAP1; DAZ-associated protein 1 isoform X3 K14411 MSI; RNA-binding protein Musashi
E 113259473 HBS1L; HBS1-like protein isoform X2 K14416 HBS1; elongation factor 1 alpha-like protein
E 113251691 PABPN1L; LOW QUALITY PROTEIN: embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 113246081 PABPN1; polyadenylate-binding protein 2 isoform X1 K14396 PABPN1; polyadenylate-binding protein 2
E 113252475 DDX19A; ATP-dependent RNA helicase DDX19A isoform X1 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 113252476 ATP-dependent RNA helicase DDX19B isoform X2 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 113259893 DDX25; ATP-dependent RNA helicase DDX25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 113242929 XAB2; pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 113256456 SARNP; SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 113268413 RCC1; regulator of chromosome condensation isoform X1 K11493 RCC1; regulator of chromosome condensation
E 113240927 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 113261815 PURA; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 113257769 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 113241690 POLDIP3; polymerase delta-interacting protein 3 K22414 POLDIP3; polymerase delta-interacting protein 3
E 113247378 LENG8; leukocyte receptor cluster member 8 isoform X2 K23802 LENG8; SAC3 family protein LENG8/THP3
E 113241927 PATL2; protein PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 113261793 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 113248821 GSPT2; eukaryotic peptide chain release factor GTP-binding subunit ERF3B K03267 ERF3; peptide chain release factor subunit 3
E 113270786 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A K03267 ERF3; peptide chain release factor subunit 3
E 113256732 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 113241064 UPF2; regulator of nonsense transcripts 2 isoform X2 K14327 UPF2; regulator of nonsense transcripts 2
E 113247571 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 113241281 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 113262137 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 113261737 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 113247257 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 113260072 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 113269966 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 113252071 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 113255341 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 113266692 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 113266124 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 113253964 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 113262671 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 113244148 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 113261281 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 113246356 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 113267251 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 113270747 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 113245240 SMG5; nonsense-mediated mRNA decay factor SMG5 isoform X1 K11125 SMG5; protein SMG5
E 113269135 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 113262735 SMG7; nonsense-mediated mRNA decay factor SMG7 isoform X2 K14409 SMG7; protein SMG7
E 113268885 SMG8; nonsense-mediated mRNA decay factor SMG8 K18734 SMG8; protein SMG8
E 113243485 SMG9; nonsense-mediated mRNA decay factor SMG9 isoform X2 K18735 SMG9; protein SMG9
E 113267848 GIGYF1; GRB10-interacting GYF protein 1 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 113250337 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 113270126 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 113269598 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 113243372 DHX34; probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 113241769 GTPBP1; GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 113270175 PUM3; pumilio homolog 3 isoform X3 K14844 PUF6; pumilio homology domain family member 6
E 113269636 MYO5C; unconventional myosin-Vc isoform X2 K10357 MYO5; myosin V
E 113269637 MYO5A; unconventional myosin-Va isoform X2 K10357 MYO5; myosin V
E 113253410 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 113270097 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 113257744 BICD1; protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
E 113242013 EXD1; piRNA biogenesis protein EXD1 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 113244519 ACTG1; actin, cytoplasmic 2 isoform X2 K05692 ACTB_G1; actin beta/gamma 1
E 113267965 ACTB; LOW QUALITY PROTEIN: actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 113253537 MBP; myelin basic protein isoform X1 K17269 MBP; myelin basic protein
E 113241367 VIM; vimentin K07606 VIM; vimentin
E 113254955 metallothionein-2E-like K14739 MT1_2; metallothionein 1/2
E 113252265 metallothionein-1 K14739 MT1_2; metallothionein 1/2
E 113252266 metallothionein-2 K14739 MT1_2; metallothionein 1/2
E 125283289 metallothionein-1 K14739 MT1_2; metallothionein 1/2
E 113252726 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 113256734 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 113267649 TBX6; LOW QUALITY PROTEIN: T-box transcription factor TBX6 K10180 TBX6; T-box protein 6
E 113251988 NANOS1; nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 113258759 ZBP1; Z-DNA-binding protein 1 isoform X4 K12965 ZBP1; Z-DNA binding protein 1
E 113254498 FUBP1; far upstream element-binding protein 1 isoform X1 K13210 FUBP; far upstream element-binding protein
E 113266523 FUBP3; far upstream element-binding protein 3 isoform X2 K13210 FUBP; far upstream element-binding protein
E 113268611 elongation factor 1-alpha, somatic form-like K03231 EEF1A; elongation factor 1-alpha
E 113258809 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 113261115 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 113245537 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 113259354 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 113263191 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 113265956 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 113265964 LOW QUALITY PROTEIN: putative elongation factor 1-alpha-like 3 K03231 EEF1A; elongation factor 1-alpha
E 113265862 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 113266168 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 113246967 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 113261750 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 113245316 HAX1; HCLS1-associated protein X-1 isoform X2 K16220 HAX1; HCLS1-associated protein X-1
E 113250379 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X7 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 113258696 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X11 K17597 STAU; double-stranded RNA-binding protein Staufen
E 113253047 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 113266880 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 113242704 PTBP1; polypyrimidine tract-binding protein 1 isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 113243165 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113263742 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X9 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113266689 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113264113 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 113254657 FXR1; RNA-binding protein FXR1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 113241891 FMR1; fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 113271143 FXR2; RNA-binding protein FXR2 isoform X2 K15516 FMR; fragile X mental retardation protein
E 113263582 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 113264018 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 113264451 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 113256933 PCBP4; poly(rC)-binding protein 4 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 113265052 CAPRIN1; caprin-1 K18743 CAPRIN1; caprin-1
E 113257754 CAPRIN2; caprin-2 isoform X6 K18744 CAPRIN2; caprin-2
E 113254807 YBX1; Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 113254016 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 113248463 AGO2; protein argonaute-2 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 113268298 AGO3; protein argonaute-3 isoform X3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 113268300 protein argonaute-4 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 113268299 AGO1; protein argonaute-1 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 113263893 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 113263123 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 113250342 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X2 K03259 EIF4E; translation initiation factor 4E
E 113256732 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 113248381 ATP-dependent RNA helicase DDX3X-like isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 113265882 DDX3X; ATP-dependent RNA helicase DDX3X isoform X2 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 113259985 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 113242655 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 113263762 MEX3B; RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 113253424 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 113245149 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 113241480 FASTK; fas-activated serine/threonine kinase isoform X5 K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 113258785 LSM14B; protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 113244737 LSM14A; protein LSM14 homolog A isoform X1 K18749 LSM14; protein LSM14
E 113244317 PCBP1; poly(rC)-binding protein 1 K12889 PCBP1; poly(rC)-binding protein 1
E 113254807 YBX1; Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 113256777 LIMD1; LIM domain-containing protein 1 K16682 AJUBA; LIM domain-containing protein
E 113244755 WTIP; Wilms tumor protein 1-interacting protein K16682 AJUBA; LIM domain-containing protein
E 113246075 AJUBA; LIM domain-containing protein ajuba K16682 AJUBA; LIM domain-containing protein
E 113258086 APOBEC1; C->U-editing enzyme APOBEC-1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 113251074 LOW QUALITY PROTEIN: DNA dC->dU-editing enzyme APOBEC-3H K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 113244416 MOV10; helicase MOV-10 isoform X2 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 113268511 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 113255230 TNPO1; transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 113270747 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 113245240 SMG5; nonsense-mediated mRNA decay factor SMG5 isoform X1 K11125 SMG5; protein SMG5
E 113269135 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 113262735 SMG7; nonsense-mediated mRNA decay factor SMG7 isoform X2 K14409 SMG7; protein SMG7
E 113246408 ZFP36L2; mRNA decay activator protein ZFP36L2 K18753 ZFP36L; butyrate response factor
E 113270402 ZFP36L1; mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 113264789 LIN28B; protein lin-28 homolog B isoform X2 K18754 LIN28; protein lin-28
E 113268459 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 113245750 HTT; huntingtin K04533 HD; huntingtin
E 113257756 IPO8; importin-8 isoform X2 K18755 IPO8; importin-8
E 113259066 BICC1; protein bicaudal C homolog 1 isoform X5 K18756 BICC1; protein bicaudal C
E 113250731 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 113257520 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 113254486 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 113247197 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha K04345 PKA; protein kinase A [EC:2.7.11.11]
E 113255656 LARP1B; la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 113263998 LARP1; LOW QUALITY PROTEIN: la-related protein 1 K18757 LARP1; la-related protein 1
E 113266967 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
E 113267629 ATXN2L; ataxin-2-like protein isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 113254985 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 113256979 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 113258048 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 113262094 LSM1; U6 snRNA-associated Sm-like protein LSm1 isoform X1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 113257226 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X2 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 113262475 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X2 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 113255727 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 113242763 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 113263369 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 113267207 KLC1; kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 113244076 KLC2; kinesin light chain 2 isoform X2 K10407 KLC; kinesin light chain
E 113261277 KLC4; kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 113243433 KLC3; kinesin light chain 3 isoform X1 K10407 KLC; kinesin light chain
E 113269636 MYO5C; unconventional myosin-Vc isoform X2 K10357 MYO5; myosin V
E 113269637 MYO5A; unconventional myosin-Va isoform X2 K10357 MYO5; myosin V
E 113253410 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 113257654 tubulin alpha-1C chain K07374 TUBA; tubulin alpha
E 113258067 TUBA8; tubulin alpha-8 chain isoform X1 K07374 TUBA; tubulin alpha
E 113245958 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 113242534 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 113241127 TUBAL3; tubulin alpha chain-like 3 K07374 TUBA; tubulin alpha
E 113250431 tubulin alpha-4A chain K07374 TUBA; tubulin alpha
E 113257653 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 113257657 tubulin alpha-1B chain K07374 TUBA; tubulin alpha
E 113243165 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113263742 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X9 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113266689 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113264113 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 113264003 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 113245668 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 113244575 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X5 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 113241750 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X7 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 113267589 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 113252309 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 113256274 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 113247382 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 113264507 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 113261545 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 113263242 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 113262161 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 113264002 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 113244739 GARRE1; granule associated Rac and RHOG effector protein 1 isoform X2 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 113250344 DIS3L2; DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 113256422 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 113251214 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 113265636 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 113243853 BTG3; protein BTG3 K14443 TOB; protein Tob/BTG
E 113256171 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 113241727 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 113259791 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 113242519 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 113245060 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X3 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 113248883 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 113240968 EDC3; enhancer of mRNA-decapping protein 3 isoform X2 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 113252386 EDC4; enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 113243266 NANOS2; nanos homolog 2 K18760 NANOS2; protein nanos 2
E 113247135 NANOS3; nanos homolog 3 K18761 NANOS3; protein nanos 3
E 113241064 UPF2; regulator of nonsense transcripts 2 isoform X2 K14327 UPF2; regulator of nonsense transcripts 2
E 113247571 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 113241281 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 113269247 TRIM21; E3 ubiquitin-protein ligase TRIM21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
E 113253761 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 113246998 POLR2G; DNA-directed RNA polymerase II subunit RPB7 isoform X2 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 113241346 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 113251239 ZAR1L; protein ZAR1-like isoform X1 K18762 ZAR1; zygote arrest protein 1
E 113262379 ZAR1; zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 113268405 YTHDF2; YTH domain-containing family protein 2 isoform X3 K20102 YTHDF; YTH domain-containing family protein
E 113268061 YTHDF3; YTH domain-containing family protein 3 isoform X3 K20102 YTHDF; YTH domain-containing family protein
E 113258805 YTHDF1; YTH domain-containing family protein 1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 113251996 TIAL1; nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 113244242 TIA1; cytotoxic granule associated RNA binding protein TIA1 isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 113242175 PABPC5; polyadenylate-binding protein 5 K13126 PABPC; polyadenylate-binding protein
E 113252872 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 113268249 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 113242138 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 113258643 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 113246576 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 113255673 PABPC4L; polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 125281205 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 113258696 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X11 K17597 STAU; double-stranded RNA-binding protein Staufen
E 113253047 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 113254657 FXR1; RNA-binding protein FXR1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 113241891 FMR1; fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 113271143 FXR2; RNA-binding protein FXR2 isoform X2 K15516 FMR; fragile X mental retardation protein
E 113258759 ZBP1; Z-DNA-binding protein 1 isoform X4 K12965 ZBP1; Z-DNA binding protein 1
E 113242911 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 113263982 G3BP1; ras GTPase-activating protein-binding protein 1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 113263263 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 113254058 EIF2A; eukaryotic translation initiation factor 2A isoform X2 K15026 EIF2A; translation initiation factor 2A
E 113247725 EIF3B; eukaryotic translation initiation factor 3 subunit B isoform X2 K03253 EIF3B; translation initiation factor 3 subunit B
E 113253897 EIF4A2; eukaryotic initiation factor 4A-II isoform X1 K03257 EIF4A; translation initiation factor 4A
E 113271150 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 113244539 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 113248378 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4B-like K03258 EIF4B; translation initiation factor 4B
E 113268553 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 113248990 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 113254213 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 113242238 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 113259645 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 113242134 RPS6KA6; ribosomal protein S6 kinase alpha-6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 113261532 RACK1; receptor of activated protein C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 113248645 TRAF2; TNF receptor-associated factor 2 isoform X3 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 113250092 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 113246935 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 125281258 nuclear RNA export factor 3-like K14284 NXF; nuclear RNA export factor
E 125281259 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 130544108 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 130544139 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 113265929 HDAC6; histone deacetylase 6 isoform X3 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 113251399 TDRD3; tudor domain-containing protein 3 isoform X2 K18404 TDRD3; tudor domain-containing protein 3
E 113257624 LARP4; la-related protein 4 isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 113256979 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 113258048 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 113254985 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 113259985 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 113240968 EDC3; enhancer of mRNA-decapping protein 3 isoform X2 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 113252386 EDC4; enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 113248883 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 113262094 LSM1; U6 snRNA-associated Sm-like protein LSm1 isoform X1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 113257226 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X2 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 113262475 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X2 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 113255727 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 113242763 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 113263369 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 113254016 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 113246784 XRN2; 5'-3' exoribonuclease 2 isoform X2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 113253933 NUDT16; U8 snoRNA-decapping enzyme K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 113259881 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 113265254 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 113251785 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 113266524 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 113260442 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 113247677 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 113243537 EXOSC5; exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 113252479 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 113256772 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 113251264 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 113255628 EXOSC9; exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 113251414 DIS3; exosome complex exonuclease RRP44 isoform X1 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 113240883 DIS3L; DIS3-like exonuclease 1 isoform X1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 113270513 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 113244751 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 113252539 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 113245509 DDX60; probable ATP-dependent RNA helicase DDX60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 113260709 TENT4A; terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 113252221 TENT4B; terminal nucleotidyltransferase 4B isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 113260448 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 113255328 MTREX; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 113243737 SKIC2; SKI2 subunit of superkiller complex protein K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 113255081 SKIC3; SKI3 subunit of superkiller complex protein K12600 SKI3; superkiller protein 3
E 113263799 SKIC8; SKI8 subunit of superkiller complex protein isoform X2 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 113261545 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 113263242 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 113252309 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 113256274 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 113247382 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 113264507 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 113262161 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 113264002 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 113250453 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 113253762 CNOT10; CCR4-NOT transcription complex subunit 10 isoform X2 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 113256422 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 113251214 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 113270774 PARN; poly(A)-specific ribonuclease PARN isoform X5 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 113259622 PNLDC1; poly(A)-specific ribonuclease PNLDC1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 113254083 DHX36; ATP-dependent DNA/RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 113265636 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 113243853 BTG3; protein BTG3 K14443 TOB; protein Tob/BTG
E 113256171 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 113241727 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 113259791 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 113242519 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 113255683 NOCT; nocturnin isoform X1 K18764 NOCT; nocturnin [EC:3.1.3.108]
E 113262115 ERI1; 3'-5' exoribonuclease 1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 113259881 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 113257005 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 113263803 IREB2; iron-responsive element-binding protein 2 isoform X1 K22416 IREB2; iron-responsive element-binding protein 2
E 113265254 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 113258813 HELZ2; helicase with zinc finger domain 2 isoform X1 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 113267366 NRDE2; nuclear exosome regulator NRDE2 isoform X1 K26109 NRDE2; nuclear exosome regulator NRDE2
E 113242354 SAMD4A; protein Smaug homolog 1 isoform X1 K27396 SMG; protein Smaug
E 113243590 SAMD4B; protein Smaug homolog 2 K27396 SMG; protein Smaug
E 113260584 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 113248482 RNASE1; ribonuclease pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 113249318 RNASE4; ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 113248493 ribonuclease 7-like K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 125282529 ribonuclease K3-like K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 113248952 RNASE11; probable ribonuclease 11 K16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]
E 113268279 ZC3H12A; endoribonuclease ZC3H12A isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 113260087 ZC3H12C; probable ribonuclease ZC3H12C isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 113259544 ZC3H12D; probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 113246886 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 113260849 DROSHA; ribonuclease 3 isoform X1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 113260032 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 113271065 ENO3; beta-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 113257953 ENO2; gamma-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 113270547 ENO1; alpha-enolase isoform X4 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 113245464 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 113241114 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 113252099 PFKL; ATP-dependent 6-phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 113257678 PFKM; ATP-dependent 6-phosphofructokinase, muscle type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 113261795 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 113250626 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 113266524 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 113251785 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 113247677 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 113256772 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024