+D Protein KO
#
Membrane Trafficking - Uncinocarpus reesii
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
D UREG_06390 cell division control protein 3 K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D UREG_07252 3-phosphoinositide-dependent protein kinase 1 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D UREG_03646 hypothetical protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D UREG_04831 similar to phospholipase K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D UREG_06962 similar to phopholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D UREG_00542 phosphatidylinositol-4-phosphate 5-kinase its3 K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D UREG_01166 serine/threonine-protein kinase PAK 3 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
D UREG_03984 serine/threonine-protein kinase 24 K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D UREG_07764 serine/threonine-protein kinase 24 K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D UREG_03878 nucleoside diphosphate kinase 1 K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D UREG_05907 similar to SNF1 family protein kinase K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D UREG_02983 neuronal calcium sensor 1 K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D UREG_02573 GTP-binding protein SAS1 K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D UREG_03296 calmodulin K02183 CALM; calmodulin
D UREG_00482 hypothetical protein K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D UREG_00717 hypothetical protein K15292 STXBP1; syntaxin-binding protein 1
D UREG_07492 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
D UREG_04232 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D UREG_07273 hypothetical protein K19953 GRTP1; TBC1 domain family member 6
D UREG_04266 hypothetical protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D UREG_01557 peroxisomal targeting signal receptor K13342 PEX5; peroxin-5
D UREG_04502 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D UREG_05132 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D UREG_07737 type II proteins geranylgeranyltransferase beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D UREG_07222 hypothetical protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D UREG_00754 cell division control protein 42 K04393 CDC42; cell division control protein 42
D UREG_00468 cell division control protein 42 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D UREG_06576 hypothetical protein K19983 EXOC1; exocyst complex component 1
D UREG_03642 hypothetical protein K17637 EXOC2; exocyst complex component 2
D UREG_05141 hypothetical protein K06110 EXOC3; exocyst complex component 3
D UREG_04205 hypothetical protein K06111 EXOC4; exocyst complex component 4
D UREG_01423 hypothetical protein K19984 EXOC5; exocyst complex component 5
D UREG_03167 hypothetical protein K19985 EXOC6; exocyst complex component 6
D UREG_06305 hypothetical protein K07195 EXOC7; exocyst complex component 7
D UREG_04715 hypothetical protein K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D UREG_03419 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
D UREG_07718 hypothetical protein K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D UREG_04522 hypothetical protein K19877 CHS5; chitin biosynthesis protein CHS5
D UREG_07262 hypothetical protein K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D UREG_00219 hypothetical protein K12481 RBSN; rabenosyn-5
D UREG_03863 hypothetical protein K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D UREG_02364 hypothetical protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D UREG_03295 hypothetical protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D UREG_06100 hypothetical protein K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D UREG_05122 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
C Bos1 / Membrin
C Sec20
D UREG_07655 hypothetical protein K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
C STX8
D UREG_00371 hypothetical protein K08501 STX8; syntaxin 8
C STX10
C Bet1
D UREG_03214 hypothetical protein K08504 BET1; blocked early in transport 1
D UREG_01184 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D UREG_01839 hypothetical protein K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D UREG_05959 SNC2 protein K08513 VAMP4; vesicle-associated membrane protein 4
D UREG_04711 hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D UREG_02806 similar to YKT6 SNARE protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D UREG_03534 protein transport protein sec22 K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D UREG_07492 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D UREG_00717 hypothetical protein K15292 STXBP1; syntaxin-binding protein 1
D UREG_06119 similar to stxbp-unc-18-sec1 family protein K19998 SCFD1; sec1 family domain-containing protein 1
D UREG_07707 hypothetical protein K26808 TXLN; taxilin
C Palmitoyltransferases
D UREG_04824 palmitoyltransferase PFA3 K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D UREG_00914 palmitoyltransferase akr1 K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D UREG_07243 vesicular-fusion protein SEC18 K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D UREG_06427 hypothetical protein K15296 NAPA; alpha-soluble NSF attachment protein
D UREG_00626 hypothetical protein K17919 SNX4; sorting nexin-4
D UREG_06238 sorting nexin-41 K21996 SNX41_42; sorting nexin-41/42
D UREG_01971 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
D UREG_04902 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
D UREG_03868 hypothetical protein K14012 NSFL1C; UBX domain-containing protein 1
D UREG_06654 protein VTS1 K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D UREG_04750 clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D UREG_01444 DNM1 protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D UREG_02636 similar to alpha-adaptin C K11824 AP2A; AP-2 complex subunit alpha
D UREG_01604 hypothetical protein K11825 AP2B1; AP-2 complex subunit beta-1
D UREG_04227 AP-2 complex subunit mu K11826 AP2M1; AP-2 complex subunit mu-1
D UREG_07194 AP-2 complex subunit sigma K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D UREG_07226 hypothetical protein K20042 FCHO; F-BAR domain only protein
D UREG_05407 similar to EPN3 protein K12471 EPN; epsin
D UREG_01713 hypothetical protein K12471 EPN; epsin
D UREG_04084 hypothetical protein K12472 EPS15; epidermal growth factor receptor substrate 15
D UREG_02339 hypothetical protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D UREG_00226 hypothetical protein K12562 AMPH; amphiphysin
D UREG_01522 hypothetical protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D UREG_07792 hypothetical protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D UREG_04427 similar to sagA protein K20048 END3; actin cytoskeleton-regulatory complex protein END3
D UREG_03219 heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D UREG_01466 heat shock protein SSB1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D UREG_00542 phosphatidylinositol-4-phosphate 5-kinase its3 K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D UREG_03353 hypothetical protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D UREG_01177 CreD protein K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D UREG_02238 pH-response regulator protein palF/RIM8 K20063 RIM8; arrestin-related trafficking adapter 9
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D UREG_04232 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D UREG_07807 hypothetical protein K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D UREG_02051 actin-regulating kinase 1 K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D UREG_05629 hypothetical protein K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D UREG_05780 E3 ubiquitin--protein ligase pub1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D UREG_00456 SLA2 protein K20040 HIP1R; huntingtin-interacting protein 1-related protein
D UREG_00619 calnexin K08054 CANX; calnexin
D UREG_05181 hypothetical protein K20069 NECAP1_2; adaptin ear-binding coat-associated protein 1/2
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D UREG_01444 DNM1 protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D UREG_05250 protein kinase C K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
D UREG_00839 hypothetical protein K07192 FLOT; flotillin
C GRAF1-dependent endocytosis
D UREG_00754 cell division control protein 42 K04393 CDC42; cell division control protein 42
D UREG_05863 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D UREG_00170 ADP-ribosylation factor 6 K07941 ARF6; ADP-ribosylation factor 6
D UREG_00468 cell division control protein 42 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D UREG_01930 protein rho5 K04513 RHOA; Ras homolog gene family, member A
D UREG_00338 protein rho4 K04513 RHOA; Ras homolog gene family, member A
D UREG_01444 DNM1 protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D UREG_02713 myosin-5 K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D UREG_00652 protein ras-1 K07827 KRAS; GTPase KRas
D UREG_00882 protein ras-2 K07827 KRAS; GTPase KRas
D UREG_00468 cell division control protein 42 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D UREG_00754 cell division control protein 42 K04393 CDC42; cell division control protein 42
C Kinases
D UREG_03695 phosphatidylinositol 3-kinase vps34 K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D UREG_02320 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D UREG_01166 serine/threonine-protein kinase PAK 3 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C Phospholipase C
D UREG_03646 hypothetical protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D UREG_00617 hypothetical protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D UREG_00226 hypothetical protein K12562 AMPH; amphiphysin
D UREG_04169 reduced viability upon starvation protein 161 K20120 BIN3; bridging integrator 3
C F-BAR proteins
D UREG_00284 hypothetical protein K20121 FNBP1; formin-binding protein 1
D UREG_07226 hypothetical protein K20042 FCHO; F-BAR domain only protein
D UREG_00465 similar to GTPase activating protein K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D UREG_02758 GTP-binding protein ypt5 K07889 RAB5C; Ras-related protein Rab-5C
D UREG_07522 vacuolar protein sorting-associated protein 21 K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D UREG_05836 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D UREG_00219 hypothetical protein K12481 RBSN; rabenosyn-5
D UREG_04232 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D UREG_03695 phosphatidylinositol 3-kinase vps34 K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D UREG_00327 similar to possible kinase with calcium binding domain K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D UREG_03096 vacuolar protein sorting-associated protein 45 K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D UREG_05863 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D UREG_00170 ADP-ribosylation factor 6 K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D UREG_01185 hypothetical protein K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D UREG_07802 similar to Stt4p: phosphatidylinositol-4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D UREG_07545 hypothetical protein K21842 EFR3; protein EFR3
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D UREG_02758 GTP-binding protein ypt5 K07889 RAB5C; Ras-related protein Rab-5C
D UREG_07522 vacuolar protein sorting-associated protein 21 K07889 RAB5C; Ras-related protein Rab-5C
D UREG_05058 GTP-binding protein ypt7 K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D UREG_07368 Vps35p protein K18468 VPS35; vacuolar protein sorting-associated protein 35
D UREG_05782 vacuolar protein sorting 29 K18467 VPS29; vacuolar protein sorting-associated protein 29
D UREG_05357 vacuolar protein sorting 26 K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D UREG_03207 hypothetical protein K16536 HOOK3; protein HOOK3
C Rab associated proteins
D UREG_03695 phosphatidylinositol 3-kinase vps34 K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D UREG_03987 proteasome component PRE6 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D UREG_01998 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D UREG_03557 GTPase-activating protein GYP7 K20168 TBC1D15; TBC1 domain family member 15
D UREG_04502 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D UREG_05132 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D UREG_07737 type II proteins geranylgeranyltransferase beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D UREG_00329 hypothetical protein K20176 SGSM3; small G protein signaling modulator 3
D UREG_01971 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
D UREG_01067 hypothetical protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D UREG_06884 L-A virus GAG protein N-acetyltransferase K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D UREG_04102 hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D UREG_02330 hypothetical protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D UREG_01157 hypothetical protein K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D UREG_01165 hypothetical protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D UREG_00232 hypothetical protein K12183 TSG101; ESCRT-I complex subunit TSG101
D UREG_02896 hypothetical protein K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D UREG_02205 hypothetical protein K12188 SNF8; ESCRT-II complex subunit VPS22
D UREG_05808 hypothetical protein K12189 VPS25; ESCRT-II complex subunit VPS25
D UREG_02651 hypothetical protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D UREG_02531 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D UREG_04941 charged multivesicular body protein 2a K12191 CHMP2A; charged multivesicular body protein 2A
D UREG_04704 hypothetical protein K12193 VPS24; charged multivesicular body protein 3
D UREG_01984 vacuolar sorting protein snf-7 K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D UREG_05073 hypothetical protein K12198 CHMP5; charged multivesicular body protein 5
D UREG_05757 hypothetical protein K12195 CHMP6; charged multivesicular body protein 6
D UREG_04858 hypothetical protein K15053 CHMP7; charged multivesicular body protein 7
D UREG_06837 similar to vacuolar sorting protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D UREG_06701 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D UREG_05606 pH-response regulator protein palA/RIM20 K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D UREG_07053 hypothetical protein K20177 VPS3; vacuolar protein sorting-associated protein 3
D UREG_06690 hypothetical protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D UREG_04652 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D UREG_05030 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D UREG_04349 similar to DigA protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D UREG_01838 similar to vacuolar sorting protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D UREG_04652 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D UREG_05030 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D UREG_04349 similar to DigA protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D UREG_01838 similar to vacuolar sorting protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D UREG_06272 similar to AvaB protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D UREG_07469 hypothetical protein K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D UREG_07222 hypothetical protein K24155 DMXL; rabconnectin-3a
C RAVE complex
D UREG_07222 hypothetical protein K24155 DMXL; rabconnectin-3a
D UREG_04186 S-phase kinase-associated protein 1A K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D UREG_07814 hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D UREG_05184 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D UREG_00561 hypothetical protein K12398 AP3M; AP-3 complex subunit mu
C BLOC-1 complex
C BLOC-1 complex (yeast)
D UREG_07244 hypothetical protein K22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D UREG_01006 hypothetical protein K20195 MON1; vacuolar fusion protein MON1
D UREG_01158 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D UREG_07638 hypothetical protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D UREG_03970 vacuolar sorting protein 1 K23481 VPS1; vacuolar protein sorting-associated protein 1
D UREG_03768 hypothetical protein K24781 BPH1; beige protein homolog 1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D UREG_04118 GTP-binding protein ypt3 K07904 RAB11A; Ras-related protein Rab-11A
C Rab4 associated proteins
D UREG_00219 hypothetical protein K12481 RBSN; rabenosyn-5
D UREG_00626 hypothetical protein K17919 SNX4; sorting nexin-4
D UREG_03684 hypothetical protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D UREG_04962 hypothetical protein K20241 WDR44; WD repeat-containing protein 44
D UREG_05643 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13
D UREG_03167 hypothetical protein K19985 EXOC6; exocyst complex component 6
D UREG_01971 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D UREG_04232 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D UREG_05836 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D UREG_03415 DNA repair protein RAD51 K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D UREG_07601 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D UREG_06554 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D UREG_06666 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D UREG_06748 F-actin capping protein beta subunit isoforms 1 and 2 K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D UREG_05782 vacuolar protein sorting 29 K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D UREG_02787 hypothetical protein K21440 ANKRD50; ankyrin repeat domain-containing protein 50
D UREG_07142 hypothetical protein K21440 ANKRD50; ankyrin repeat domain-containing protein 50
D UREG_07721 hypothetical protein K21440 ANKRD50; ankyrin repeat domain-containing protein 50
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D UREG_00345 GTP-binding protein ryh1 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D UREG_01971 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
D UREG_04266 hypothetical protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D UREG_03393 hypothetical protein K20286 TMF1; TATA element modulatory factor
D UREG_06531 hypothetical protein K04648 DCTN1; dynactin 1
D UREG_04232 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D UREG_05306 hypothetical protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D UREG_05863 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D UREG_01587 ADP-ribosylation factor 6 K07942 ARL1; ADP-ribosylation factor-like protein 1
D UREG_02954 hypothetical protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D UREG_04314 hypothetical protein K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D UREG_02158 hypothetical protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D UREG_01185 hypothetical protein K12486 SMAP; stromal membrane-associated protein
D UREG_07799 hypothetical protein K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
D UREG_06264 hypothetical protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D UREG_05245 hypothetical protein K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D UREG_03519 hypothetical protein K20288 COG1; conserved oligomeric Golgi complex subunit 1
D UREG_03871 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D UREG_07497 hypothetical protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D UREG_00950 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D UREG_05452 hypothetical protein K20293 COG6; conserved oligomeric Golgi complex subunit 6
D UREG_07339 hypothetical protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D UREG_07601 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D UREG_06554 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D UREG_06666 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D UREG_03959 hypothetical protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D UREG_04167 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D UREG_05666 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D UREG_00786 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D UREG_02105 trafficking protein particle complex subunit 3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D UREG_01390 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D UREG_03160 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D UREG_04854 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D UREG_03056 similar to hypercellular protein A K20306 TRAPPC9; trafficking protein particle complex subunit 9
D UREG_03613 hypothetical protein K20307 TRAPPC10; trafficking protein particle complex subunit 10
D UREG_05743 hypothetical protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D UREG_07372 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
D UREG_05602 hypothetical protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D UREG_02085 AP-1 complex subunit gamma-1 K12391 AP1G1; AP-1 complex subunit gamma-1
D UREG_07595 oxidation resistance protein 1 K12392 AP1B1; AP-1 complex subunit beta-1
D UREG_03826 AP-1 complex subunit mu-1 K12393 AP1M; AP-1 complex subunit mu
D UREG_00236 AP-1 complex subunit theta-1 K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D UREG_07814 hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D UREG_05184 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D UREG_00561 hypothetical protein K12398 AP3M; AP-3 complex subunit mu
C AP-4 complex
C GGA
D UREG_01958 hypothetical protein K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D UREG_03523 hypothetical protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D UREG_04831 similar to phospholipase K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D UREG_06962 similar to phopholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D UREG_07802 similar to Stt4p: phosphatidylinositol-4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D UREG_00542 phosphatidylinositol-4-phosphate 5-kinase its3 K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D UREG_02320 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D UREG_01749 hypothetical protein K20316 SCOC; short coiled-coil protein
D UREG_06870 hypothetical protein K20318 SYS1; protein SYS1
D UREG_00425 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D UREG_06817 hypothetical protein K23542 TMEM199; TMEM199 family protein
D UREG_00489 hypothetical protein K23543 CCDC115; coiled-coil domain-containing protein 115
D UREG_06513 hypothetical protein K23544 SERINC1; serine incorporator 1
D UREG_00442 sorting nexin-3 K17918 SNX3_12; sorting nexin-3/12
D UREG_04915 Mvp1p protein K17922 SNX8; sorting nexin-8
D UREG_05359 hypothetical protein K26678 MON2; protein MON2
D UREG_01005 hypothetical protein K26680 DOP1; protein dopey
D UREG_00646 hypothetical protein K26750 TVP15; golgi apparatus membrane protein TVP15
D UREG_07394 hypothetical protein K26751 TVP18; golgi apparatus membrane protein TVP18
D UREG_00638 hypothetical protein K26752 TVP23; golgi apparatus membrane protein TVP23
D UREG_00635 hypothetical protein K26753 TVP38; golgi apparatus membrane protein TVP38
D UREG_03970 vacuolar sorting protein 1 K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D UREG_06646 GTP-binding protein sarA K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D UREG_05643 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13
D UREG_06441 Sec31 protein K14005 SEC31; protein transport protein SEC31
D UREG_06707 60S ribosomal protein L12 K14006 SEC23; protein transport protein SEC23
D UREG_05431 SEC24 protein K14007 SEC24; protein transport protein SEC24
D UREG_06860 hypothetical protein K14007 SEC24; protein transport protein SEC24
D UREG_03554 hypothetical protein K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D UREG_04167 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D UREG_05666 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D UREG_00786 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D UREG_02105 trafficking protein particle complex subunit 3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D UREG_01390 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D UREG_03160 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D UREG_01913 hypothetical protein K20346 TMED4_9_11; p24 family protein alpha
D UREG_05882 endosomal P24B protein K20347 TMED2; p24 family protein beta-1
D UREG_05164 early meiotic induction protein 5 K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D UREG_05680 protein disulfide-isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D UREG_05040 protein disulfide-isomerase tigA K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D UREG_06694 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D UREG_03181 Rab2B protein K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D UREG_07843 hypothetical protein K20359 RABAC1; PRA1 family protein 1
D UREG_06550 hypothetical protein K20372 TBC1D20; TBC1 domain family member 20
D UREG_00936 TBC1 domain family member 22A K20360 TBC1D22; TBC1 domain family member 2
D UREG_03561 hypothetical protein K20362 YIF1; protein transport protein YIF1
D UREG_07219 AousoA protein K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D UREG_04867 hypothetical protein K10080 LMAN1; lectin, mannose-binding 1
D UREG_06327 hypothetical protein K10082 LMAN2; lectin, mannose-binding 2
D UREG_05468 similar to class I alpha-mannosidase 1A K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D UREG_04973 hypothetical protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D UREG_07143 mannosyl-oligosaccharide 1,2-alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D UREG_04850 similar to class I alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D UREG_07868 mannosyl-oligosaccharide 1,2-alpha-mannosidase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D UREG_00240 hypothetical protein K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D UREG_06668 hypothetical protein K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D UREG_02292 ER-derived vesicles protein ERV14 K20368 CNIH; protein cornichon
D UREG_05855 hypothetical protein K20369 ERV29; ER-derived vesicles protein
D UREG_01160 heat shock protein 70 K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D UREG_07591 coatomer alpha subunit K05236 COPA; coatomer subunit alpha
D UREG_05914 coatomer beta subunit K17301 COPB1; coatomer subunit beta
D UREG_02221 coatomer beta' subunit K17302 COPB2; coatomer subunit beta'
D UREG_05505 similar to coatomer protein complex K17267 COPG; coatomer subunit gamma
D UREG_02864 similar to ARCN1 protein K20471 COPD; coatomer subunit delta
C NRZ (DSL1) complex
D UREG_07482 hypothetical protein K20474 RINT1; RAD50-interacting protein 1
D UREG_04765 hypothetical protein K11578 ZW10; protein transport protein DSL1/ZW10
D UREG_02066 hypothetical protein K20475 SEC39; protein transport protein SEC39
C Golgi to ER traffic proteins (GET)
D UREG_05616 hypothetical protein K22384 GET1; tail-anchored protein insertion receptor
D UREG_05081 hypothetical protein K22386 GET2; GET complex subunit GET2
D UREG_07455 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D UREG_03132 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
D UREG_04022 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
C Rab GTPases
D UREG_00345 GTP-binding protein ryh1 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D UREG_03459 hypothetical protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D UREG_06406 hypothetical protein K20477 RGP1; RAB6A-GEF complex partner protein 2
D UREG_04064 ER lumen protein retaining receptor 2 K10949 KDELR; ER lumen protein retaining receptor
D UREG_00219 hypothetical protein K12481 RBSN; rabenosyn-5
D UREG_00936 TBC1 domain family member 22A K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D UREG_07567 hypothetical protein K20456 OSBP; oxysterol-binding protein 1
D UREG_06925 OSBPL2 protein K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
D UREG_01694 similar to oxysterol-binding protein K22285 OSBPL8; oxysterol-binding protein-related protein 8
D UREG_06973 hypothetical protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
D UREG_07410 Kes1p protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D UREG_06551 hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D UREG_02597 hypothetical protein K20363 YIPF5_7; protein YIPF5/7
D UREG_02679 hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D UREG_03762 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D UREG_06997 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D UREG_01567 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D UREG_05890 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D UREG_06655 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
C SEC61 complex
D UREG_04191 preprotein translocase, SecY subunit K10956 SEC61A; protein transport protein SEC61 subunit alpha
D UREG_06640 hypothetical protein K09481 SEC61B; protein transport protein SEC61 subunit beta
D UREG_00440 translocase SEC61 complex gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D UREG_03277 hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D UREG_06363 hypothetical protein K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D UREG_07326 hypothetical protein K23553 PGAP3; post-GPI attachment to proteins factor 3
D UREG_07702 hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D UREG_06119 similar to stxbp-unc-18-sec1 family protein K19998 SCFD1; sec1 family domain-containing protein 1
D UREG_06388 hypothetical protein K20724 TMEM33; transmembrane protein 33
D UREG_06300 beta-glucan synthesis-associated protein SKN1 K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D UREG_01971 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
D UREG_04752 hypothetical protein K26681 INSIG; insulin-induced protein
D UREG_03379 protein sey1 K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D UREG_01152 hypothetical protein K08331 ATG13; autophagy-related protein 13
D UREG_04380 hypothetical protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D UREG_02473 similar to ULK3 protein K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D UREG_01152 hypothetical protein K08331 ATG13; autophagy-related protein 13
D UREG_06360 hypothetical protein K08329 ATG17; autophagy-related protein 17
C PI3K complex
D UREG_03695 phosphatidylinositol 3-kinase vps34 K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D UREG_00327 similar to possible kinase with calcium binding domain K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D UREG_01552 hypothetical protein K08334 BECN; beclin
C ATG9 transmembrane protein
D UREG_05467 hypothetical protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D UREG_05219 hypothetical protein K17908 WIPI1_2; autophagy-related protein 18
D UREG_05385 hypothetical protein K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D UREG_01132 hypothetical protein K08336 ATG12; ubiquitin-like protein ATG12
D UREG_05678 E1-like protein-activating enzyme Gsa7p/Apg7p K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D UREG_02243 hypothetical protein K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D UREG_03209 gamma-aminobutyric acid receptor associated protein K08341 GABARAP; GABA(A) receptor-associated protein
D UREG_06991 hypothetical protein K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D UREG_05678 E1-like protein-activating enzyme Gsa7p/Apg7p K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D UREG_04393 similar to autophagocytosis protein AUT1 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D UREG_03805 hypothetical protein K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D UREG_07684 similar to mannosidase II K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D UREG_07671 similar to aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D UREG_07424 hypothetical protein K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D UREG_06238 sorting nexin-41 K21996 SNX41_42; sorting nexin-41/42
D UREG_00626 hypothetical protein K17919 SNX4; sorting nexin-4
D UREG_01578 hypothetical protein K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D UREG_07077 hypothetical protein K21141 ATG27; autophagy-related protein 27
D UREG_04961 vacuolar protein 8 K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D UREG_07424 hypothetical protein K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D UREG_04942 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D UREG_06934 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other mitophagy associated proteins
D UREG_04499 glucokinase K00844 HK; hexokinase [EC:2.7.1.1]
D UREG_00948 hexokinase K00844 HK; hexokinase [EC:2.7.1.1]
D UREG_01635 hypothetical protein K00844 HK; hexokinase [EC:2.7.1.1]
D UREG_06287 glucokinase K00844 HK; hexokinase [EC:2.7.1.1]
D UREG_06121 hexokinase K00844 HK; hexokinase [EC:2.7.1.1]
D UREG_01747 hypothetical protein K22255 ATPIF1; ATPase inhibitor, mitochondrial
D UREG_04270 hypothetical protein K19717 ATG33; autophagy-related protein 33
B Pexophagy
C Selective cargos
D UREG_04381 hypothetical protein K13336 PEX3; peroxin-3
D UREG_07351 hypothetical protein K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
D UREG_06934 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
D UREG_07733 similar to peroxin-1 K13338 PEX1; peroxin-1
D UREG_01405 peroxisomal biogenesis factor 6 K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
D UREG_06934 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Scaffold proteins
C Other aggrephagy associated proteins
D UREG_04902 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
D UREG_02233 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
D UREG_06934 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D UREG_02186 aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D UREG_01031 similar to aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D UREG_04000 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D UREG_02318 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D UREG_03499 deubiquitination-protection protein dph1 K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D UREG_03219 heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D UREG_01466 heat shock protein SSB1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D UREG_01901 heat shock protein 82 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D UREG_07557 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha
D UREG_06044 carboxypeptidase Y K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
D UREG_03020 carboxypeptidase Y K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D UREG_04961 vacuolar protein 8 K08332 VAC8; vacuolar protein 8
C Midbophagy
D UREG_06934 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D UREG_04942 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D UREG_01609 phosphatidylinositol 3-kinase tor2 K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D UREG_05786 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
D UREG_05516 WD-repeat protein mip1 K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D UREG_01609 phosphatidylinositol 3-kinase tor2 K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D UREG_05786 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
D UREG_06329 hypothetical protein K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D UREG_01591 hypothetical protein K08267 RICTOR; rapamycin-insensitive companion of mTOR
C SEACIT/GATOR1 complex
D UREG_00696 hypothetical protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D UREG_06611 hypothetical protein K20405 NPRL2; nitrogen permease regulator 2
D UREG_03465 hypothetical protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D UREG_01773 hypothetical protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D UREG_04483 hypothetical protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D UREG_02002 hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D UREG_02457 hypothetical protein K14299 SEH1; nucleoporin SEH1
D UREG_05643 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D UREG_02573 GTP-binding protein SAS1 K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D UREG_04602 serine/threonine-protein phosphatase PP2A catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D UREG_05229 similar to TapA protein K17606 IGBP1; immunoglobulin-binding protein 1
D UREG_04938 hypothetical protein K21249 UVRAG; UV radiation resistance-associated gene protein
D UREG_00924 hypothetical protein K06902 UMF1; MFS transporter, UMF1 family
D UREG_04743 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D UREG_03686 hypothetical protein K22991 WDR45; WD repeat-containing protein 45
D UREG_07648 hypothetical protein K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21
D UREG_02374 hypothetical protein K27411 PHAF1; phagosome assembly factor 1
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
D UREG_03491 similar to NADPH oxidase K08008 NOX1; NADPH oxidase 1
D UREG_00528 NADPH oxidase K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
C Nox associated proteins
D UREG_00468 cell division control protein 42 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D UREG_02713 myosin-5 K10356 MYO1; myosin I
D UREG_04039 MYO2 protein K10357 MYO5; myosin V
C Arp2/3 complex
D UREG_07839 similar to Arp2/3 complex chain sop2 K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D UREG_06771 ARP2/3 complex 34 kDa subunit K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D UREG_04011 ARP2/3 complex 21 kDa subunit K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D UREG_04486 ARP2/3 complex 20 kDa subunit K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D UREG_04451 actin K17260 ACTR2; actin-related protein 2
D UREG_05207 actin K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D UREG_04519 hypothetical protein K23612 WASL; neural Wiskott-Aldrich syndrome protein
D UREG_01446 hypothetical protein K20520 DBNL; drebrin-like protein
D UREG_07792 hypothetical protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D UREG_00226 hypothetical protein K12562 AMPH; amphiphysin
D UREG_01522 hypothetical protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D UREG_01605 hypothetical protein K20521 BBC1; myosin tail region-interacting protein MTI1
D UREG_07612 hypothetical protein K20522 LSB1_2; LAS seventeen-binding protein 1/2
D UREG_01181 similar to Sh3yl1 protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D UREG_01250 hypothetical protein K20524 LSB5; LAS seventeen-binding protein 5
D UREG_06516 similar to phosphatidylinositol 4-kinase type-II beta K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D UREG_02803 profilin-2 K05759 PFN; profilin
D UREG_04106 hypothetical protein K05765 CFL; cofilin
D UREG_03636 hypothetical protein K17261 CAP1_2; adenylyl cyclase-associated protein
D UREG_02972 kinesin heavy chain K10396 KIF5; kinesin family member 5
D UREG_05159 hypothetical protein K20526 TAGLN; transgelin
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
C Lipid droplets
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D UREG_00465 similar to GTPase activating protein K20643 RGD1; Rho GTPase-activating protein RGD1
D UREG_07830 hypothetical protein K08773 RALBP1; RalA-binding protein 1
C Rho guanine nucleotide exchange factors (GEFs)
D UREG_07748 hypothetical protein K20705 DNMBP; dynamin-binding protein
D UREG_06575 hypothetical protein K05727 DOCK3; dedicator of cytokinesis protein 3
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 20, 2024