+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Vibrio cholerae O1 2012EL-2176</h2>
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A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    EN18_15630 UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    EN18_18460 UDP-N-acetylenolpyruvoylglucosamine reductase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    EN18_15045 murC; UDP-N-acetylmuramate--alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    EN18_15060 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    EN18_15075 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase	K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] 
C    EN18_01280 D-alanine--D-alanine ligase	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
B  Racemase
C    EN18_18790 alr; alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    EN18_16790 glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
B  Glycosyltransferase
C    EN18_15065 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    EN18_15050 murG; UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
C    EN18_19600 UDP pyrophosphate phosphatase	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] 
C    EN18_15465 membrane protein	K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] 
B  Flippase
C    EN18_06810 multidrug transporter MurJ	K03980 murJ; putative peptidoglycan lipid II flippase 
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A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    EN18_16205 penicillin-sensitive transpeptidase	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
C    EN18_05960 peptidase	K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] 
B  DD-Transpeptidase (Class B PBP)
C    EN18_08095 penicillin-binding protein 2	K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] 
C    EN18_15080 cell division protein FtsI	K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    EN18_00080 D-alanyl-D-alanine carboxypeptidase	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
C    EN18_08080 D-alanyl-D-alanine carboxypeptidase	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
C    EN18_06105 D-alanyl-D-alanine carboxypeptidase	K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] 
C    EN18_02645 pbpG; D-alanyl-D-alanine endopeptidase	K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-] 
B  Glycosyltransferase
C    EN18_15055 cell division protein FtsW	K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] 
C    EN18_08090 rod shape-determining protein RodA	K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28] 
B  Transpeptidase
C    EN18_04040 peptidase	K19236 ycfS; L,D-transpeptidase YcfS 
C    EN18_09630 peptidase	K21470 ycbB; L,D-transpeptidase YcbB 
B  Carboxypeptidase
B  Endopeptidase
C    EN18_04130 peptidase M23	K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] 
B  Sortase
B  Lytic transglycosylase
C    EN18_06900 lytic murein transglycosylase	K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
C    EN18_14650 murein transglycosylase	K08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29] 
C    EN18_12890 lytic transglycosylase	K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] 
C    EN18_19285 murein transglycosylase	K08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29] 
C    EN18_14285 murein transglycosylase	K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29] 
C    EN18_07695 murein transglycosylase	K18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29] 
C    EN18_13185 hypothetical protein	K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] 
C    EN18_08085 lipoprotein	K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
B  Amidase
C    EN18_18655 N-acetylmuramoyl-L-alanine amidase	K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
C    EN18_15140 N-acetyl-anhydromuranmyl-L-alanine amidase	K03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28] 
B  Structural protein
C    EN18_04045 membrane protein	K06078 lpp; murein lipoprotein 
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#Last updated: May 15, 2025