+C Two-component system KO
#
Two-Component System - Vibrio cholerae O1 O395
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C VC395_0737 phoR; histidine protein kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C VC395_0736 phoB; DNA-binding response regulator PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
C VC395_2825 envZ; osmolarity sensor protein EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C VC395_2826 ompR; transcriptional regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C VC395_1438 sensor histidine kinase K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C VC395_1439 DNA-binding response regulator K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C VC395_2806 cpxA; sensor protein CpxA K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
C VC395_2805 cpxR; transcriptional regulator CpxR K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
C VC395_A1125 sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C VC395_A1126 DNA-binding response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C VC395_A0793 sensor histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C VC395_A0792 DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
C VC395_A0603 torS; sensor protein TorS K07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
C VC395_1836 torR; DNA-binding response regulator TorR K07772 torR; two-component system, OmpR family, torCAD operon response regulator TorR
B ArcB-ArcA (anoxic redox control)
C VC395_2484 fexB; sensor histidine kinase FexB K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
C VC395_2483 fexA; aerobic respiration control protein K07773 arcA; two-component system, OmpR family, aerobic respiration control protein ArcA
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C VC395_1755 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C VC395_A0276 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
#
ANarL family
B NarX-NarL (nitrate respiration)
C VC395_1396 transcriptional regulator, LuxR family K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
C VC395_A0637 narQ; nitrate/nitrite sensor protein NarQ K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
C VC395_A0638 narP; nitrate/nitrite response regulator NarP K07685 narP; two-component system, NarL family, nitrate/nitrite response regulator NarP
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
C VC395_A0629 uhpB; sensor protein UhpB K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]
C VC395_A0630 uhpA; transcriptional regulator UhpA K20264 fusR; two-component system, NarL family, response regulator FusR
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C VC395_2568 sensor histidine kinase/response regulator K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C VC395_1332 transcriptional regulator, LuxR family K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C VC395_1770 vieS; sensory box sensor histidine kinase/response regulator VieS K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
C VC395_1395 sensor histidine kinase K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
#
ASpo family
B KinABCDE-Spo0FA (sporulation control)
#
ACitB family
B CitA-CitB (citrate fermentation)
C VC395_0808 citA; sensor kinase citA K07700 dpiB; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
C VC395_0807 citB; transcriptional regulator CitB K07702 dpiA; two-component system, CitB family, response regulator CitB
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
C VC395_1721 putative sensor kinase citA K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
C VC395_1720 response regulator K02475 K02475; two-component system, CitB family, response regulator
#
ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B BtsS-BtsR (pyruvate reutilization)
C VC395_0711 GAF/HisKin family protein K27882 btsS; two-component system, LytTR family, low-concentration pyruvate sensor kinase [EC:2.7.13.3]
C VC395_0710 response regulator K27883 btsR; two-component system, LytTR family, low-concentration pyruvate response regulator
B PyrS-PyrR (pyruvate reutilization)
B Unclassified
#
ANtrC family
B GlnL-GlnG (nitrogen regulation)
C VC395_2860 ntrB; nitrogen regulation protein K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C VC395_2861 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
C VC395_A0607 putative phosphoglycerate transport regulatory protein PgtB K08475 pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]
C VC395_A0608 phosphoglycerate transport system transcriptional regulatory protein PgtA K08476 pgtA; two-component system, NtrC family, phosphoglycerate transport system response regulator PgtA
B DctB-DctD (C4-dicarboxylate transport)
C VC395_2040 dctB; putative C4-dicarboxylate transport sensor protein K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C VC395_A0134 putative C4-dicarboxylate transport sensor protein K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C VC395_2041 dctD-1; putative C4-dicarboxylate transport transcriptional regulatory protein K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C VC395_A0135 dctD-2; C4-dicarboxylate transport transcriptional regulatory protein K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C VC395_1099 sensory box sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C VC395_1640 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
#
ACheA family
B CheA-CheYBV (chemotaxis)
C VC395_1516 cheA-1; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C VC395_2178 cheA-2; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C VC395_A1116 cheA-3; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C VC395_1097 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C VC395_1435 putative chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C VC395_1514 cheY-1; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C VC395_1517 cheY-2; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C VC395_2180 cheY-3; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C VC395_A1117 cheY-4; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C VC395_1520 cheB-1; protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C VC395_2177 cheB-2; protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C VC395_A1110 cheB-3; protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C VC395_1718 cheV-1; chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C VC395_2121 cheV-2; chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C VC395_2318 cheV-3; chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C VC395_A0979 putative chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
#
ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
#
ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
C VC395_A0578 luxQ; sensor histidine kinase LuxQ K10909 luxQ; two-component system, autoinducer 2 sensor kinase/phosphatase LuxQ [EC:2.7.13.3 3.1.3.-]
C VC395_A0802 luxN; sensor histidine kinase/response regulator LuxN K10916 cqsS; two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
C VC395_1036 luxU; phosphorelay protein K10911 luxU; two-component system, phosphorelay protein LuxU
C VC395_1035 luxO; LuxO repressor protein K10912 luxO; two-component system, repressor protein LuxO
#
ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
#
AOther families
B FlrB-FlrC (polar flagellar synthesis)
C VC395_2250 flrB; flagellar regulatory protein B K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C VC395_2249 flrC; flagellar regulatory protein C K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C VC395_1095 Hpt family protein K20976 hptB; histidine phosphotransfer protein HptB
C VC395_A1107 response regulator K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C VC395_0639 sensory box sensor histidine kinase/response regulator K19694 chiS; two-component system, sensor histidine kinase ChiS
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 8, 2024