+F Repair protein KO
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DNA Repair and Recombination Proteins - Vescimonas fastidiosa
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MM35RIKEN_04650 ogt1; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MM35RIKEN_04200 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MM35RIKEN_14940 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MM35RIKEN_04560 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MM35RIKEN_04240 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MM35RIKEN_17600 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MM35RIKEN_04650 ogt1; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MM35RIKEN_21510 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MM35RIKEN_04200 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MM35RIKEN_14940 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MM35RIKEN_04560 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MM35RIKEN_17250 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E MM35RIKEN_15880 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MM35RIKEN_06690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MM35RIKEN_07840 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MM35RIKEN_24150 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MM35RIKEN_13920 polA; DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MM35RIKEN_11390 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E MM35RIKEN_11450 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E MM35RIKEN_18210 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E MM35RIKEN_05650 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MM35RIKEN_13920 polA; DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MM35RIKEN_06690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MM35RIKEN_07840 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MM35RIKEN_24150 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MM35RIKEN_19640 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MM35RIKEN_19630 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MM35RIKEN_19280 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MM35RIKEN_05390 hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MM35RIKEN_13630 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MM35RIKEN_17010 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E MM35RIKEN_07380 endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
E MM35RIKEN_18390 mutS2; endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E MM35RIKEN_17000 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MM35RIKEN_06010 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MM35RIKEN_06020 hypothetical protein K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MM35RIKEN_05860 dnaE; DNA-directed DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MM35RIKEN_02090 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E MM35RIKEN_17340 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MM35RIKEN_01330 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MM35RIKEN_17110 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MM35RIKEN_21860 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MM35RIKEN_06690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MM35RIKEN_07840 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MM35RIKEN_24150 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MM35RIKEN_05650 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MM35RIKEN_08410 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E MM35RIKEN_16420 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E MM35RIKEN_18620 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MM35RIKEN_23480 hypothetical protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MM35RIKEN_07790 recD2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MM35RIKEN_11370 recD2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MM35RIKEN_24210 recD2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MM35RIKEN_19460 DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E MM35RIKEN_06550 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MM35RIKEN_06540 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MM35RIKEN_06560 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MM35RIKEN_16510 hypothetical protein K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E MM35RIKEN_05400 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E MM35RIKEN_19460 DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E MM35RIKEN_06240 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MM35RIKEN_17360 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E MM35RIKEN_18220 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MM35RIKEN_15880 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MM35RIKEN_18370 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MM35RIKEN_10860 recR; recombination protein RecR K06187 recR; recombination protein RecR
E MM35RIKEN_06100 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MM35RIKEN_06550 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MM35RIKEN_06540 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MM35RIKEN_06560 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E MM35RIKEN_04480 addA; ATP-dependent helicase/nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E MM35RIKEN_04470 addB; ATP-dependent helicase/deoxyribonuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MM35RIKEN_15790 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MM35RIKEN_17390 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MM35RIKEN_15770 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MM35RIKEN_17380 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MM35RIKEN_21710 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MM35RIKEN_15950 transcriptional regulator K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MM35RIKEN_15880 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MM35RIKEN_18370 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MM35RIKEN_10860 recR; recombination protein RecR K06187 recR; recombination protein RecR
F MM35RIKEN_06690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F MM35RIKEN_07840 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F MM35RIKEN_24150 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MM35RIKEN_11390 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F MM35RIKEN_11450 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MM35RIKEN_20720 DNA methylase K03502 umuC; DNA polymerase V
D MM35RIKEN_22300 DNA methylase K03502 umuC; DNA polymerase V
C Other SOS response factors
D MM35RIKEN_19460 DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
D MM35RIKEN_21880 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MM35RIKEN_06100 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MM35RIKEN_08410 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D MM35RIKEN_16420 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D MM35RIKEN_18620 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MM35RIKEN_23480 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D MM35RIKEN_19470 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MM35RIKEN_20630 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MM35RIKEN_04240 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MM35RIKEN_17600 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
D MM35RIKEN_18470 DHH family phosphoesterase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024