+D GENES KO #

  KEGG Orthology (KO) - Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:wbr00010] D pgi Energy metabolism K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D fbp Energy metabolism K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D fba Energy metabolism K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D tpiA Energy metabolism K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D gapA Energy metabolism K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D pgk Energy metabolism K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D gpmA Energy metabolism K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D eno Energy metabolism K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D pykA Energy metabolism K00873 PK; pyruvate kinase [EC:2.7.1.40] D aceE Energy metabolism K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D aceF Energy metabolism K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D pgm Energy metabolism K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D pckA Energy metabolism K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00020 Citrate cycle (TCA cycle) [PATH:wbr00020] D sucA Energy metabolism K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D sucB Energy metabolism K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D sucD Energy metabolism K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D sucC Energy metabolism K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D sdhA Energy metabolism K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D sdhB Energy metabolism K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D sdhC Energy metabolism K00241 sdhC; succinate dehydrogenase cytochrome b subunit D sdhD Unclassified K00242 sdhD; succinate dehydrogenase membrane anchor subunit D fumC Energy metabolism K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D yojH Energy metabolism K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4] D pckA Energy metabolism K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D aceE Energy metabolism K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D aceF Energy metabolism K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:wbr00030] D pgi Energy metabolism K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D rpe Energy metabolism K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D tktB Energy metabolism K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D talA Energy metabolism K00616 TALDO1; transaldolase [EC:2.2.1.2] D rpiA Energy metabolism K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D pgm Energy metabolism K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D prsA Purines, pyrimidines, nucleosides, and nucleotides K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D fba Energy metabolism K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D fbp Energy metabolism K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] C 00040 Pentose and glucuronate interconversions [PATH:wbr00040] D ugd Purines, pyrimidines, nucleosides, and nucleotides K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D galU Cell envelope K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D rpe Energy metabolism K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:wbr00051] D fbp Energy metabolism K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D fba Energy metabolism K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D tpiA Energy metabolism K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism [PATH:wbr00052] D galU Cell envelope K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D pgm Energy metabolism K01835 pgm; phosphoglucomutase [EC:5.4.2.2] C 00053 Ascorbate and aldarate metabolism D ugd Purines, pyrimidines, nucleosides, and nucleotides K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] C 00500 Starch and sucrose metabolism [PATH:wbr00500] D galU Cell envelope K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D pgm Energy metabolism K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D pgi Energy metabolism K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] C 00620 Pyruvate metabolism [PATH:wbr00620] D aceE Energy metabolism K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D aceF Energy metabolism K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ackA Energy metabolism K00925 ackA; acetate kinase [EC:2.7.2.1] D pta Energy metabolism K13788 pta; phosphate acetyltransferase [EC:2.3.1.8] D pykA Energy metabolism K00873 PK; pyruvate kinase [EC:2.7.1.40] D accA Fatty acid and phospholipid metabolism K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D accB Fatty acid and phospholipid metabolism K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D accC Fatty acid and phospholipid metabolism K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D accD Fatty acid and phospholipid metabolism K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D gloB Energy metabolism K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D ycbL Unknown function K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D yojH Energy metabolism K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4] D fumC Energy metabolism K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D pckA Energy metabolism K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:wbr00630] D glnA Amino acid biosynthesis K01915 glnA; glutamine synthetase [EC:6.3.1.2] D glyA Amino acid biosynthesis K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D purU Purines, pyrimidines, nucleosides, and nucleotides K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] C 00640 Propanoate metabolism [PATH:wbr00640] D ackA Energy metabolism K00925 ackA; acetate kinase [EC:2.7.2.1] D pta Energy metabolism K13788 pta; phosphate acetyltransferase [EC:2.3.1.8] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D accA Fatty acid and phospholipid metabolism K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D accB Fatty acid and phospholipid metabolism K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D accC Fatty acid and phospholipid metabolism K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D accD Fatty acid and phospholipid metabolism K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D sucC Energy metabolism K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D sucD Energy metabolism K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00650 Butanoate metabolism D sdhA Energy metabolism K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D sdhB Energy metabolism K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D sdhC Energy metabolism K00241 sdhC; succinate dehydrogenase cytochrome b subunit D sdhD Unclassified K00242 sdhD; succinate dehydrogenase membrane anchor subunit C 00660 C5-Branched dibasic acid metabolism D sucC Energy metabolism K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D sucD Energy metabolism K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00562 Inositol phosphate metabolism [PATH:wbr00562] D suhB Central intermediary metabolism K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D tpiA Energy metabolism K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:wbr00190] D ndh Energy metabolism K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D sdhA Energy metabolism K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D sdhB Energy metabolism K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D sdhC Energy metabolism K00241 sdhC; succinate dehydrogenase cytochrome b subunit D sdhD Unclassified K00242 sdhD; succinate dehydrogenase membrane anchor subunit D cyoE Energy metabolism K02257 COX10; heme o synthase [EC:2.5.1.141] D cyoD Energy metabolism K02300 cyoD; cytochrome o ubiquinol oxidase subunit IV D cyoC Energy metabolism K02299 cyoC; cytochrome o ubiquinol oxidase subunit III D cyoB Energy metabolism K02298 cyoB; cytochrome o ubiquinol oxidase subunit I [EC:7.1.1.3] D cyoA Energy metabolism K02297 cyoA; cytochrome o ubiquinol oxidase subunit II [EC:7.1.1.3] D atpA Energy metabolism K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D atpD Energy metabolism K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D atpG Energy metabolism K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D atpH Energy metabolism K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D atpC Energy metabolism K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D atpB Energy metabolism K02108 ATPF0A; F-type H+-transporting ATPase subunit a D atpF Energy metabolism K02109 ATPF0B; F-type H+-transporting ATPase subunit b D atpE Energy metabolism K02110 ATPF0C; F-type H+-transporting ATPase subunit c D ppa Central intermediary metabolism K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation by Calvin cycle [PATH:wbr00710] D pgk Energy metabolism K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D gapA Energy metabolism K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D fba Energy metabolism K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D fbp Energy metabolism K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D tktB Energy metabolism K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D rpiA Energy metabolism K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D tpiA Energy metabolism K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D rpe Energy metabolism K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D talA Energy metabolism K00616 TALDO1; transaldolase [EC:2.2.1.2] D pckA Energy metabolism K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00720 Other carbon fixation pathways [PATH:wbr00720] D fumC Energy metabolism K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D sdhA Energy metabolism K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D sdhB Energy metabolism K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D sdhC Energy metabolism K00241 sdhC; succinate dehydrogenase cytochrome b subunit D sdhD Unclassified K00242 sdhD; succinate dehydrogenase membrane anchor subunit D sucD Energy metabolism K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D sucC Energy metabolism K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D accA Fatty acid and phospholipid metabolism K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D accB Fatty acid and phospholipid metabolism K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D accC Fatty acid and phospholipid metabolism K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D accD Fatty acid and phospholipid metabolism K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D folD Biosynthesis of cofactors, prosthetic groups, and carrier K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D pta Energy metabolism K13788 pta; phosphate acetyltransferase [EC:2.3.1.8] D ackA Energy metabolism K00925 ackA; acetate kinase [EC:2.7.2.1] C 00680 Methane metabolism [PATH:wbr00680] D glyA Amino acid biosynthesis K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D eno Energy metabolism K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D fba Energy metabolism K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D fbp Energy metabolism K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D ackA Energy metabolism K00925 ackA; acetate kinase [EC:2.7.2.1] D pta Energy metabolism K13788 pta; phosphate acetyltransferase [EC:2.3.1.8] D gpmA Energy metabolism K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D serC Amino acid biosynthesis K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00910 Nitrogen metabolism D glnA Amino acid biosynthesis K01915 glnA; glutamine synthetase [EC:6.3.1.2] C 00920 Sulfur metabolism B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:wbr00061] D accA Fatty acid and phospholipid metabolism K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D accB Fatty acid and phospholipid metabolism K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D accC Fatty acid and phospholipid metabolism K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D accD Fatty acid and phospholipid metabolism K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D acpP Fatty acid and phospholipid metabolism K02078 acpP; acyl carrier protein D fabD Fatty acid and phospholipid metabolism K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D fabB Fatty acid and phospholipid metabolism K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D fabG Fatty acid and phospholipid metabolism K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D fabA Fatty acid and phospholipid metabolism K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D fabI Fatty acid and phospholipid metabolism K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C 00062 Fatty acid elongation C 00071 Fatty acid degradation C 00073 Cutin, suberine and wax biosynthesis C 00074 Mycolic acid biosynthesis [PATH:wbr00074] D acpS Fatty acid and phospholipid metabolism K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D acpP Fatty acid and phospholipid metabolism K02078 acpP; acyl carrier protein D fabD Fatty acid and phospholipid metabolism K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:wbr00561] D plsB Fatty acid and phospholipid metabolism K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] D plsC Fatty acid and phospholipid metabolism K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 00564 Glycerophospholipid metabolism [PATH:wbr00564] D gpsA Energy metabolism K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D plsB Fatty acid and phospholipid metabolism K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] D plsC Fatty acid and phospholipid metabolism K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D cdsA Fatty acid and phospholipid metabolism K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D pssA Fatty acid and phospholipid metabolism K00998 pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D psd Fatty acid and phospholipid metabolism K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D pgsA Fatty acid and phospholipid metabolism K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D pgpA Hypothetical proteins K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27] D cls Fatty acid and phospholipid metabolism K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:wbr00230] D pgm Energy metabolism K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D prsA Purines, pyrimidines, nucleosides, and nucleotides K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D purF Purines, pyrimidines, nucleosides, and nucleotides K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D purD Purines, pyrimidines, nucleosides, and nucleotides K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D purT Purines, pyrimidines, nucleosides, and nucleotides K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] D purL Purines, pyrimidines, nucleosides, and nucleotides K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D purM Purines, pyrimidines, nucleosides, and nucleotides K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D purK Purines, pyrimidines, nucleosides, and nucleotides K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D purE Purines, pyrimidines, nucleosides, and nucleotides K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D purC Purines, pyrimidines, nucleosides, and nucleotides K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D purB Purines, pyrimidines, nucleosides, and nucleotides K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D purH Purines, pyrimidines, nucleosides, and nucleotides K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D surE Cellular processes K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D guaB Purines, pyrimidines, nucleosides, and nucleotides K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D ndk Purines, pyrimidines, nucleosides, and nucleotides K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D yggV Unknown function K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D guaA Purines, pyrimidines, nucleosides, and nucleotides K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D gmk Purines, pyrimidines, nucleosides, and nucleotides K00942 gmk; guanylate kinase [EC:2.7.4.8] D nrdE Purines, pyrimidines, nucleosides, and nucleotides K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D nrdF Purines, pyrimidines, nucleosides, and nucleotides K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D purA Purines, pyrimidines, nucleosides, and nucleotides K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D adk Purines, pyrimidines, nucleosides, and nucleotides K00939 adk; adenylate kinase [EC:2.7.4.3] D apaH Cellular processes K01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41] C 00240 Pyrimidine metabolism [PATH:wbr00240] D carB Purines, pyrimidines, nucleosides, and nucleotides K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D carA Purines, pyrimidines, nucleosides, and nucleotides K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D pyrB Purines, pyrimidines, nucleosides, and nucleotides K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D pyrI Purines, pyrimidines, nucleosides, and nucleotides K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D pyrC Purines, pyrimidines, nucleosides, and nucleotides K01465 URA4; dihydroorotase [EC:3.5.2.3] D pyrD Purines, pyrimidines, nucleosides, and nucleotides K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2] D pyrE Purines, pyrimidines, nucleosides, and nucleotides K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D pyrF Purines, pyrimidines, nucleosides, and nucleotides K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D pyrH Purines, pyrimidines, nucleosides, and nucleotides K09903 pyrH; uridylate kinase [EC:2.7.4.22] D ndk Purines, pyrimidines, nucleosides, and nucleotides K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D pyrG Purines, pyrimidines, nucleosides, and nucleotides K01937 pyrG; CTP synthase [EC:6.3.4.2] D cmk Purines, pyrimidines, nucleosides, and nucleotides K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D surE Cellular processes K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D dcd Purines, pyrimidines, nucleosides, and nucleotides K01494 dcd; dCTP deaminase [EC:3.5.4.13] D nrdE Purines, pyrimidines, nucleosides, and nucleotides K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D nrdF Purines, pyrimidines, nucleosides, and nucleotides K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D tmk Purines, pyrimidines, nucleosides, and nucleotides K00943 tmk; dTMP kinase [EC:2.7.4.9] D dut Purines, pyrimidines, nucleosides, and nucleotides K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D thyA Purines, pyrimidines, nucleosides, and nucleotides K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:wbr00250] D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] D asnB Amino acid biosynthesis K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D aspA Energy metabolism K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1] D purA Purines, pyrimidines, nucleosides, and nucleotides K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D purB Purines, pyrimidines, nucleosides, and nucleotides K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D pyrB Purines, pyrimidines, nucleosides, and nucleotides K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D pyrI Purines, pyrimidines, nucleosides, and nucleotides K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D putA Energy metabolism K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D glnA Amino acid biosynthesis K01915 glnA; glutamine synthetase [EC:6.3.1.2] D carB Purines, pyrimidines, nucleosides, and nucleotides K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D carA Purines, pyrimidines, nucleosides, and nucleotides K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D glmS Central intermediary metabolism K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D purF Purines, pyrimidines, nucleosides, and nucleotides K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:wbr00260] D thrA Amino acid biosynthesis K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D asd Cell envelope K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D glyA Amino acid biosynthesis K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D gpmA Energy metabolism K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D serC Amino acid biosynthesis K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D pssA Fatty acid and phospholipid metabolism K00998 pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] C 00270 Cysteine and methionine metabolism [PATH:wbr00270] D metK Central intermediary metabolism K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D pfs Unknown function K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D thrA Amino acid biosynthesis K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D asd Cell envelope K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D gshA Biosynthesis of cofactors, prosthetic groups, and carrier K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D gshB Biosynthesis of cofactors, prosthetic groups, and carrier K01920 gshB; glutathione synthase [EC:6.3.2.3] D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] D serC Amino acid biosynthesis K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00280 Valine, leucine and isoleucine degradation [PATH:wbr00280] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00290 Valine, leucine and isoleucine biosynthesis C 00300 Lysine biosynthesis [PATH:wbr00300] D thrA Amino acid biosynthesis K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D asd Cell envelope K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D dapA Amino acid biosynthesis K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D dapB Amino acid biosynthesis K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D dapD Amino acid biosynthesis K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117] D dapE Amino acid biosynthesis K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D dapF Amino acid biosynthesis K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D murE Cell envelope K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D murF Cell envelope K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:wbr00310] D sucB Energy metabolism K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00220 Arginine biosynthesis [PATH:wbr00220] D glnA Amino acid biosynthesis K01915 glnA; glutamine synthetase [EC:6.3.1.2] D carB Purines, pyrimidines, nucleosides, and nucleotides K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D carA Purines, pyrimidines, nucleosides, and nucleotides K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] C 00330 Arginine and proline metabolism [PATH:wbr00330] D proC Amino acid biosynthesis K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D putA Energy metabolism K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism C 00350 Tyrosine metabolism D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] C 00360 Phenylalanine metabolism D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] C 00380 Tryptophan metabolism D sucB Energy metabolism K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:wbr00400] D aroF Amino acid biosynthesis K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D aroK Amino acid biosynthesis K00891 aroK; shikimate kinase [EC:2.7.1.71] D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism D panC Biosynthesis of cofactors, prosthetic groups, and carrier K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] C 00430 Taurine and hypotaurine metabolism [PATH:wbr00430] D pta Energy metabolism K13788 pta; phosphate acetyltransferase [EC:2.3.1.8] D ackA Energy metabolism K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:wbr00450] D b1680 Hypothetical proteins K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D trxB Purines, pyrimidines, nucleosides, and nucleotides K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D metG Protein synthesis K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism D glyA Amino acid biosynthesis K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:wbr00470] D dadX Cell envelope K01775 alr; alanine racemase [EC:5.1.1.1] D ddlA Cell envelope K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D murI Cell envelope K01776 murI; glutamate racemase [EC:5.1.1.3] D murD Cell envelope K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D dapF Amino acid biosynthesis K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] C 00480 Glutathione metabolism [PATH:wbr00480] D gshA Biosynthesis of cofactors, prosthetic groups, and carrier K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D gshB Biosynthesis of cofactors, prosthetic groups, and carrier K01920 gshB; glutathione synthase [EC:6.3.2.3] D pepA Protein fate K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] B B 09107 Glycan biosynthesis and metabolism C 00520 Amino sugar and nucleotide sugar metabolism [PATH:wbr00520] D glmU Cell envelope K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D murA Cell envelope K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D murB Cell envelope K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D mrsA Cell envelope K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D glmS Central intermediary metabolism K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D pgi Energy metabolism K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D pgm Energy metabolism K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D galU Cell envelope K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D ugd Purines, pyrimidines, nucleosides, and nucleotides K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] C 00541 Biosynthesis of various nucleotide sugars [PATH:wbr00541] D glmU Cell envelope K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D yrbH Energy metabolism K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] D kdsA Cell envelope K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D kdsB Cell envelope K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D galU Cell envelope K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D ugd Purines, pyrimidines, nucleosides, and nucleotides K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D b2255 Protein synthesis K10011 arnA; UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305] D b2254 Cell envelope K10012 arnC; undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [EC:2.4.2.53] D b2256 Hypothetical proteins K13014 arnD; undecaprenyl phosphate-alpha-L-ara4FN deformylase [EC:3.5.1.-] D wecE Cell envelope K02805 wecE; dTDP-4-amino-4,6-dideoxygalactose transaminase [EC:2.6.1.59] C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis [PATH:wbr00540] D lpxA Cell envelope K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D lpxC Cell envelope K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] D lpxD Cell envelope K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D ybbF Hypothetical proteins K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D lpxB Cell envelope K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D ycaH Cell envelope K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D kdtA Cell envelope K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D b2257 Unclassified K07264 arnT; 4-amino-4-deoxy-L-arabinose transferase [EC:2.4.2.43] C 00542 O-Antigen repeat unit biosynthesis C 00550 Peptidoglycan biosynthesis [PATH:wbr00550] D murA Cell envelope K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D murB Cell envelope K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D murC Cell envelope K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D murD Cell envelope K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D murE Cell envelope K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D ddlA Cell envelope K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D murF Cell envelope K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D yaeS Biosynthesis of cofactors, prosthetic groups, and carrier K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D bacA Cellular processes K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D mraY Cell envelope K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D murG Cell envelope K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D mrcB Cell envelope K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] D ftsW Cellular processes K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] D mrdB Cell envelope K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28] D mrdA Cell envelope K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D ftsI Cellular processes K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D dacA Cell envelope K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C 00552 Teichoic acid biosynthesis [PATH:wbr00552] D bacA Cellular processes K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:wbr00730] D thiC Biosynthesis of cofactors, prosthetic groups, and carrier K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D thiD Biosynthesis of cofactors, prosthetic groups, and carrier K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D yfhO Biosynthesis of cofactors, prosthetic groups, and carrier K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D thiH Biosynthesis of cofactors, prosthetic groups, and carrier K03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19] D dxs Biosynthesis of cofactors, prosthetic groups, and carrier K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D thiG Biosynthesis of cofactors, prosthetic groups, and carrier K03149 thiG; thiazole synthase [EC:2.8.1.10] D thiE Biosynthesis of cofactors, prosthetic groups, and carrier K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D thiL Biosynthesis of cofactors, prosthetic groups, and carrier K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D adk Purines, pyrimidines, nucleosides, and nucleotides K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:wbr00740] D ribA Biosynthesis of cofactors, prosthetic groups, and carrier K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D ribD Biosynthesis of cofactors, prosthetic groups, and carrier K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D yigB Central intermediary metabolism K20862 yigB; FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104] D ribB Biosynthesis of cofactors, prosthetic groups, and carrier K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D ribH Biosynthesis of cofactors, prosthetic groups, and carrier K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D ribE Biosynthesis of cofactors, prosthetic groups, and carrier K00793 ribE; riboflavin synthase [EC:2.5.1.9] D ribF Biosynthesis of cofactors, prosthetic groups, and carrier K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D ubiX Cellular processes K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:wbr00750] D pdxH Biosynthesis of cofactors, prosthetic groups, and carrier K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] D pdxB Biosynthesis of cofactors, prosthetic groups, and carrier K03473 pdxB; erythronate-4-phosphate dehydrogenase [EC:1.1.1.290] D serC Amino acid biosynthesis K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D pdxA Biosynthesis of cofactors, prosthetic groups, and carrier K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262] D pdxJ Biosynthesis of cofactors, prosthetic groups, and carrier K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2] C 00760 Nicotinate and nicotinamide metabolism [PATH:wbr00760] D nadA Biosynthesis of cofactors, prosthetic groups, and carrier K03517 nadA; quinolinate synthase [EC:2.5.1.72] D nadC Biosynthesis of cofactors, prosthetic groups, and carrier K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D surE Cellular processes K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D ybeN Hypothetical proteins K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D nadE Biosynthesis of cofactors, prosthetic groups, and carrier K01916 nadE; NAD+ synthase [EC:6.3.1.5] D yfjB Unclassified K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:wbr00770] D panB Biosynthesis of cofactors, prosthetic groups, and carrier K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D apbA Biosynthesis of cofactors, prosthetic groups, and carrier K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D panC Biosynthesis of cofactors, prosthetic groups, and carrier K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D coaA Biosynthesis of cofactors, prosthetic groups, and carrier K00867 coaA; type I pantothenate kinase [EC:2.7.1.33] D dfp Unknown function K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D kdtB Cell envelope K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D yacE Unknown function K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D acpS Fatty acid and phospholipid metabolism K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] C 00780 Biotin metabolism [PATH:wbr00780] D bioC Biosynthesis of cofactors, prosthetic groups, and carrier K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197] D fabB Fatty acid and phospholipid metabolism K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D fabG Fatty acid and phospholipid metabolism K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D fabI Fatty acid and phospholipid metabolism K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D bioH Biosynthesis of cofactors, prosthetic groups, and carrier K02170 bioH; pimeloyl-[acyl-carrier protein] methyl ester esterase [EC:3.1.1.85] D bioF Biosynthesis of cofactors, prosthetic groups, and carrier K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D bioA Biosynthesis of cofactors, prosthetic groups, and carrier K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D bioD Biosynthesis of cofactors, prosthetic groups, and carrier K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] D bioB Biosynthesis of cofactors, prosthetic groups, and carrier K01012 bioB; biotin synthase [EC:2.8.1.6] D birA Regulatory functions K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:wbr00785] D lipB Protein fate K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181] D lipA Biosynthesis of cofactors, prosthetic groups, and carrier K03644 lipA; lipoyl synthase [EC:2.8.1.8] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D aceE Energy metabolism K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D aceF Energy metabolism K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D sucA Energy metabolism K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D sucB Energy metabolism K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] C 00790 Folate biosynthesis [PATH:wbr00790] D folE Biosynthesis of cofactors, prosthetic groups, and carrier K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D ygiG Biosynthesis of cofactors, prosthetic groups, and carrier K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D folK Biosynthesis of cofactors, prosthetic groups, and carrier K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D folP Biosynthesis of cofactors, prosthetic groups, and carrier K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D folA Biosynthesis of cofactors, prosthetic groups, and carrier K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D folC Biosynthesis of cofactors, prosthetic groups, and carrier K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D ribA Biosynthesis of cofactors, prosthetic groups, and carrier K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] C 00670 One carbon pool by folate [PATH:wbr00670] D folA Biosynthesis of cofactors, prosthetic groups, and carrier K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D folD Biosynthesis of cofactors, prosthetic groups, and carrier K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D glyA Amino acid biosynthesis K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D purH Purines, pyrimidines, nucleosides, and nucleotides K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D thyA Purines, pyrimidines, nucleosides, and nucleotides K00560 thyA; thymidylate synthase [EC:2.1.1.45] D purU Purines, pyrimidines, nucleosides, and nucleotides K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D metK Central intermediary metabolism K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:wbr00860] D gltX Protein synthesis K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D hemA Biosynthesis of cofactors, prosthetic groups, and carrier K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D hemL Biosynthesis of cofactors, prosthetic groups, and carrier K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D hemB Biosynthesis of cofactors, prosthetic groups, and carrier K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D hemC Biosynthesis of cofactors, prosthetic groups, and carrier K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D hemD Biosynthesis of cofactors, prosthetic groups, and carrier K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D hemE Biosynthesis of cofactors, prosthetic groups, and carrier K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D hemF Biosynthesis of cofactors, prosthetic groups, and carrier K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3] D hemG Hypothetical proteins K00230 hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3] D hemH Biosynthesis of cofactors, prosthetic groups, and carrier K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] D cyoE Energy metabolism K02257 COX10; heme o synthase [EC:2.5.1.141] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:wbr00130] D ubiA Biosynthesis of cofactors, prosthetic groups, and carrier K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D yigC Hypothetical proteins K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98] D ubiX Cellular processes K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D ubiG Biosynthesis of cofactors, prosthetic groups, and carrier K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64] D ubiH Biosynthesis of cofactors, prosthetic groups, and carrier K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-] D ubiE Biosynthesis of cofactors, prosthetic groups, and carrier K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D yleB Unknown function K03184 ubiF; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:wbr00900] D dxs Biosynthesis of cofactors, prosthetic groups, and carrier K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D yaeM Biosynthesis of cofactors, prosthetic groups, and carrier K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267] D ygbP Unknown function K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60] D ychB Unknown function K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D ygbB Hypothetical proteins K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12] D gcpE Unknown function K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3] D lytB Cellular processes K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] D ubiX Cellular processes K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D ispA Biosynthesis of cofactors, prosthetic groups, and carrier K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D ispB Biosynthesis of cofactors, prosthetic groups, and carrier K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D yaeS Biosynthesis of cofactors, prosthetic groups, and carrier K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D tktB Energy metabolism K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:wbr00261] D thrA Amino acid biosynthesis K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D asd Cell envelope K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D dapA Amino acid biosynthesis K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D dapB Amino acid biosynthesis K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:wbr00521] D pgm Energy metabolism K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D suhB Central intermediary metabolism K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis C 00401 Novobiocin biosynthesis D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis C 00333 Prodigiosin biosynthesis D fabD Fatty acid and phospholipid metabolism K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D fabG Fatty acid and phospholipid metabolism K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D fabI Fatty acid and phospholipid metabolism K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D acpP Fatty acid and phospholipid metabolism K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites D metK Central intermediary metabolism K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation C 00627 Aminobenzoate degradation D ubiX Cellular processes K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:wbr03020] D rpoB Transcription K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D rpoC Transcription K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D rpoA Transcription K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D rpoZ Transcription K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:wbr03010] D rrsH-1 rrsH K01977 16SrRNA; 16S ribosomal RNA D rrsH-2 rrsH K01977 16SrRNA; 16S ribosomal RNA D rrlB-1 rrlB K01980 23SrRNA; 23S ribosomal RNA D rrlB-2 rrlB K01980 23SrRNA; 23S ribosomal RNA D rrfA-1 rrfA K01985 5SrRNA; 5S ribosomal RNA D rrfA-2 rrfA K01985 5SrRNA; 5S ribosomal RNA D rpsA Protein synthesis K02945 RP-S1; small subunit ribosomal protein S1 D rpsB Protein synthesis K02967 RP-S2; small subunit ribosomal protein S2 D rpsC Protein synthesis K02982 RP-S3; small subunit ribosomal protein S3 D rpsD Protein synthesis K02986 RP-S4; small subunit ribosomal protein S4 D rpsE Protein synthesis K02988 RP-S5; small subunit ribosomal protein S5 D rpsF Protein synthesis K02990 RP-S6; small subunit ribosomal protein S6 D rpsG Protein synthesis K02992 RP-S7; small subunit ribosomal protein S7 D rpsH Protein synthesis K02994 RP-S8; small subunit ribosomal protein S8 D rpsI Protein synthesis K02996 RP-S9; small subunit ribosomal protein S9 D rpsJ Protein synthesis K02946 RP-S10; small subunit ribosomal protein S10 D rpsK Protein synthesis K02948 RP-S11; small subunit ribosomal protein S11 D rpsL Protein synthesis K02950 RP-S12; small subunit ribosomal protein S12 D rpsM Protein synthesis K02952 RP-S13; small subunit ribosomal protein S13 D rpsN Protein synthesis K02954 RP-S14; small subunit ribosomal protein S14 D rpsO Protein synthesis K02956 RP-S15; small subunit ribosomal protein S15 D rpsP Protein synthesis K02959 RP-S16; small subunit ribosomal protein S16 D rpsQ Protein synthesis K02961 RP-S17; small subunit ribosomal protein S17 D rpsR Protein synthesis K02963 RP-S18; small subunit ribosomal protein S18 D rpsS Protein synthesis K02965 RP-S19; small subunit ribosomal protein S19 D rpsT Protein synthesis K02968 RP-S20; small subunit ribosomal protein S20 D rpsU Protein synthesis K02970 RP-S21; small subunit ribosomal protein S21 D rplA Protein synthesis K02863 RP-L1; large subunit ribosomal protein L1 D rplB Protein synthesis K02886 RP-L2; large subunit ribosomal protein L2 D rplC Protein synthesis K02906 RP-L3; large subunit ribosomal protein L3 D rplD Protein synthesis K02926 RP-L4; large subunit ribosomal protein L4 D rplE Protein synthesis K02931 RP-L5; large subunit ribosomal protein L5 D rplF Protein synthesis K02933 RP-L6; large subunit ribosomal protein L6 D rplI Protein synthesis K02939 RP-L9; large subunit ribosomal protein L9 D rplJ Protein synthesis K02864 RP-L10; large subunit ribosomal protein L10 D rplK Protein synthesis K02867 RP-L11; large subunit ribosomal protein L11 D rplL Protein synthesis K02935 RP-L7; large subunit ribosomal protein L7/L12 D rplM Protein synthesis K02871 RP-L13; large subunit ribosomal protein L13 D rplN Protein synthesis K02874 RP-L14; large subunit ribosomal protein L14 D rplO Protein synthesis K02876 RP-L15; large subunit ribosomal protein L15 D rplP Protein synthesis K02878 RP-L16; large subunit ribosomal protein L16 D rplQ Protein synthesis K02879 RP-L17; large subunit ribosomal protein L17 D rplR Protein synthesis K02881 RP-L18; large subunit ribosomal protein L18 D rplS Protein synthesis K02884 RP-L19; large subunit ribosomal protein L19 D rplT Protein synthesis K02887 RP-L20; large subunit ribosomal protein L20 D rplU Protein synthesis K02888 RP-L21; large subunit ribosomal protein L21 D rplV Protein synthesis K02890 RP-L22; large subunit ribosomal protein L22 D rplW Protein synthesis K02892 RP-L23; large subunit ribosomal protein L23 D rplX Protein synthesis K02895 RP-L24; large subunit ribosomal protein L24 D rpmA Protein synthesis K02899 RP-L27; large subunit ribosomal protein L27 D rpmB Protein synthesis K02902 RP-L28; large subunit ribosomal protein L28 D rpmC Protein synthesis K02904 RP-L29; large subunit ribosomal protein L29 D rpmD Protein synthesis K02907 RP-L30; large subunit ribosomal protein L30 D rpmE Protein synthesis K02909 RP-L31; large subunit ribosomal protein L31 D rpmF Protein synthesis K02911 RP-L32; large subunit ribosomal protein L32 D rpmG Protein synthesis K02913 RP-L33; large subunit ribosomal protein L33 D rpmH Protein synthesis K02914 RP-L34; large subunit ribosomal protein L34 D rpmI Protein synthesis K02916 RP-L35; large subunit ribosomal protein L35 D rpmJ Protein synthesis K02919 RP-L36; large subunit ribosomal protein L36 C 00970 Aminoacyl-tRNA biosynthesis [PATH:wbr00970] D ala-GGC ala-GGC K14218 tRNA-Ala; tRNA Ala D ala-TGC ala-TGC K14218 tRNA-Ala; tRNA Ala D arg-ACG arg-ACG K14219 tRNA-Arg; tRNA Arg D arg-CCG arg-CCG K14219 tRNA-Arg; tRNA Arg D arg-TCT arg-TCT K14219 tRNA-Arg; tRNA Arg D asn-GTT asn-GTT K14220 tRNA-Asn; tRNA Asn D asp-GTC asp-GTC K14221 tRNA-Asp; tRNA Asp D cys-GCA cys-GCA K14222 tRNA-Cys; tRNA Cys D gln-TTG gln-TTG K14223 tRNA-Gln; tRNA Gln D glu-TTC-1 glu-TTC K14224 tRNA-Glu; tRNA Glu D glu-TTC-2 glu-TTC K14224 tRNA-Glu; tRNA Glu D gly-GCC gly-GCC K14225 tRNA-Gly; tRNA Gly D gly-TCC gly-TCC K14225 tRNA-Gly; tRNA Gly D his-GTG his-GTG K14226 tRNA-His; tRNA His D ile-GAT ile-GAT K14227 tRNA-Ile; tRNA Ile D leu-CAA leu-CAA K14228 tRNA-Leu; tRNA Leu D leu-GAG leu-GAG K14228 tRNA-Leu; tRNA Leu D leu-TAA leu-TAA K14228 tRNA-Leu; tRNA Leu D leu-TAG leu-TAG K14228 tRNA-Leu; tRNA Leu D lys-TTT lys-TTT K14229 tRNA-Lys; tRNA Lys D met-CAT-1 met-CAT K14230 tRNA-Met; tRNA Met D met-CAT-2 met-CAT K14230 tRNA-Met; tRNA Met D met-CAT-3 met-CAT K14230 tRNA-Met; tRNA Met D phe-GAA phe-GAA K14231 tRNA-Phe; tRNA Phe D pro-TGG pro-TGG K14232 tRNA-Pro; tRNA Pro D ser-GCT ser-GCT K14233 tRNA-Ser; tRNA Ser D ser-GGA ser-GGA K14233 tRNA-Ser; tRNA Ser D ser-TGA ser-TGA K14233 tRNA-Ser; tRNA Ser D thr-GGT thr-GGT K14234 tRNA-Thr; tRNA Thr D thr-TGT thr-TGT K14234 tRNA-Thr; tRNA Thr D trp-CCA trp-CCA K14235 tRNA-Trp; tRNA Trp D tyr-GTA tyr-GTA K14236 tRNA-Tyr; tRNA Tyr D val-GAC val-GAC K14237 tRNA-Val; tRNA Val D val-TAC val-TAC K14237 tRNA-Val; tRNA Val D gltX Protein synthesis K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D glnS Protein synthesis K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D alaS Protein synthesis K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D aspS Protein synthesis K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D asnS Protein synthesis K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D glyQ Protein synthesis K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D glyS Protein synthesis K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D thrS Protein synthesis K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D serS Protein synthesis K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D cysS Protein synthesis K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D metG Protein synthesis K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D fmt Protein synthesis K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D valS Protein synthesis K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D leuS Protein synthesis K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D ileS Protein synthesis K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D lysS Protein synthesis K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D argS Protein synthesis K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D proS Protein synthesis K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D hisS Protein synthesis K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D pheS Protein synthesis K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D pheT Protein synthesis K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D tyrS Protein synthesis K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D trpS Protein synthesis K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes [PATH:wbr03008] D rnc Transcription K03685 rnc; ribonuclease III [EC:3.1.26.3] D yjeR Transcription K13288 orn; oligoribonuclease [EC:3.1.-.-] B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:wbr03060] D prlA Protein fate K03076 secY; preprotein translocase subunit SecY D secE Protein fate K03073 secE; preprotein translocase subunit SecE D secG Protein fate K03075 secG; preprotein translocase subunit SecG D yajC Protein fate K03210 yajC; preprotein translocase subunit YajC D yidC Unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase D secA Protein fate K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ffh Protein fate K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D ftsY Cellular processes K03110 ftsY; fused signal recognition particle receptor D lepB Protein fate K03100 lepB; signal peptidase I [EC:3.4.21.89] D lspA Protein fate K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum D htpG Protein fate K04079 HSP90A; molecular chaperone HtpG C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:wbr04122] D yfhO Biosynthesis of cofactors, prosthetic groups, and carrier K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ycfB Protein synthesis K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] C 03050 Proteasome C 03018 RNA degradation [PATH:wbr03018] D rne Transcription K08300 rne; ribonuclease E [EC:3.1.26.12] D eno Energy metabolism K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D pnp Transcription K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D deaD Transcription K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D rho Transcription K03628 rho; transcription termination factor Rho D dnaK Protein fate K04043 dnaK; molecular chaperone DnaK D mopA Protein fate K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D hfq Regulatory functions K03666 hfq; host factor-I protein B B 09124 Replication and repair C 03030 DNA replication [PATH:wbr03030] D holE Hypothetical proteins K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] D dnaQ DNA metabolism K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D dnaE DNA metabolism K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D dnaX DNA metabolism K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D holB DNA metabolism K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D holA DNA metabolism K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D dnaN DNA metabolism K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D dnaB DNA metabolism K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D dnaG DNA metabolism K02316 dnaG; DNA primase [EC:2.7.7.101] D ssb DNA metabolism K03111 ssb; single-strand DNA-binding protein D rnhA Transcription K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D lig DNA metabolism K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:wbr03410] D nth DNA metabolism K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D ung DNA metabolism K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D xthA DNA metabolism K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] D recJ DNA metabolism K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D lig DNA metabolism K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:wbr03420] D mfd DNA metabolism K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D uvrD DNA metabolism K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D lig DNA metabolism K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:wbr03430] D uvrD DNA metabolism K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D recJ DNA metabolism K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D ssb DNA metabolism K03111 ssb; single-strand DNA-binding protein D dnaE DNA metabolism K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D dnaN DNA metabolism K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D dnaX DNA metabolism K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D holA DNA metabolism K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D holB DNA metabolism K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D dnaQ DNA metabolism K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D holE Hypothetical proteins K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] D lig DNA metabolism K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:wbr03440] D recJ DNA metabolism K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D ssb DNA metabolism K03111 ssb; single-strand DNA-binding protein D recA DNA metabolism K03553 recA; recombination protein RecA D ruvC DNA metabolism K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D recB DNA metabolism K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] D recC DNA metabolism K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] D recD DNA metabolism K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D dnaE DNA metabolism K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D dnaN DNA metabolism K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D dnaX DNA metabolism K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D holA DNA metabolism K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D holB DNA metabolism K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D dnaQ DNA metabolism K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D holE Hypothetical proteins K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus and Alphavirus C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus C 03273 Virion - Lassa virus and SFTS virus C 03272 Virion - Hepatitis viruses C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:wbr02010] D yebI Cell envelope K09816 znuB; zinc transport system permease protein D yebM Transport and binding proteins K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D ycfU Hypothetical proteins K09808 lolC_E_F; lipoprotein-releasing system permease protein D ycfW Hypothetical proteins K09808 lolC_E_F; lipoprotein-releasing system permease protein D ycfV Transport and binding proteins K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D yjgP Hypothetical proteins K07091 lptF; lipopolysaccharide export system permease protein D yjgQ Hypothetical proteins K11720 lptG; lipopolysaccharide export system permease protein D yhbG Transport and binding proteins K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D msbA Transport and binding proteins K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] D mdl Transport and binding proteins K18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump D mdlB Transport and binding proteins K18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:wbr03070] D secE Protein fate K03073 secE; preprotein translocase subunit SecE D secG Protein fate K03075 secG; preprotein translocase subunit SecG D prlA Protein fate K03076 secY; preprotein translocase subunit SecY D yajC Protein fate K03210 yajC; preprotein translocase subunit YajC D yidC Unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase D secA Protein fate K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ftsY Cellular processes K03110 ftsY; fused signal recognition particle receptor D ffh Protein fate K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:wbr02020] D cpxR Regulatory functions K07662 cpxR; two-component system, OmpR family, response regulator CpxR D flhD Cellular processes K02403 flhD; flagellar transcriptional activator FlhD D flhC Cellular processes K02402 flhC; flagellar transcriptional activator FlhC D fliC Cellular processes K02406 fliC; flagellin D fliA Cellular processes K02405 fliA; RNA polymerase sigma factor FliA D motA Cellular processes K02556 motA; chemotaxis protein MotA D glnA Amino acid biosynthesis K01915 glnA; glutamine synthetase [EC:6.3.1.2] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04082 Neuroactive ligand signaling C 04081 Hormone signaling C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome D sodA Cellular processes K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1] C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:wbr02024] D hfq Regulatory functions K03666 hfq; host factor-I protein D aroF Amino acid biosynthesis K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D flhD Cellular processes K02403 flhD; flagellar transcriptional activator FlhD D flhC Cellular processes K02402 flhC; flagellar transcriptional activator FlhC D ribA Biosynthesis of cofactors, prosthetic groups, and carrier K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D ribD Biosynthesis of cofactors, prosthetic groups, and carrier K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D yidC Unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase D secE Protein fate K03073 secE; preprotein translocase subunit SecE D secG Protein fate K03075 secG; preprotein translocase subunit SecG D prlA Protein fate K03076 secY; preprotein translocase subunit SecY D yajC Protein fate K03210 yajC; preprotein translocase subunit YajC D secA Protein fate K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ftsY Cellular processes K03110 ftsY; fused signal recognition particle receptor D ffh Protein fate K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:wbr02030] D fliG Cellular processes K02410 fliG; flagellar motor switch protein FliG D fliM Cellular processes K02416 fliM; flagellar motor switch protein FliM D fliN Cellular processes K02417 fliN; flagellar motor switch protein FliN D motA Cellular processes K02556 motA; chemotaxis protein MotA D motB Cellular processes K02557 motB; chemotaxis protein MotB C 02040 Flagellar assembly [PATH:wbr02040] D fliE Cellular processes K02408 fliE; flagellar hook-basal body complex protein FliE D fliF Cellular processes K02409 fliF; flagellar M-ring protein FliF D fliG Cellular processes K02410 fliG; flagellar motor switch protein FliG D fliH Cellular processes K02411 fliH; flagellar assembly protein FliH D fliI Cellular processes K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D fliJ Cellular processes K02413 fliJ; flagellar protein FliJ D fliL Hypothetical proteins K02415 fliL; flagellar protein FliL D fliM Cellular processes K02416 fliM; flagellar motor switch protein FliM D fliN Cellular processes K02417 fliN; flagellar motor switch protein FliN D fliO Cellular processes K02418 fliO; flagellar protein FliO/FliZ D fliP Cellular processes K02419 fliP; flagellar biosynthesis protein FliP D fliQ Cellular processes K02420 fliQ; flagellar biosynthesis protein FliQ D fliR Cellular processes K02421 fliR; flagellar biosynthesis protein FliR D flhA Cellular processes K02400 flhA; flagellar biosynthesis protein FlhA D flhB Cellular processes K02401 flhB; flagellar biosynthesis protein FlhB D flgA Cellular processes K02386 flgA; flagellar basal body P-ring formation protein FlgA D flgB Cell envelope K02387 flgB; flagellar basal-body rod protein FlgB D flgC Cell envelope K02388 flgC; flagellar basal-body rod protein FlgC D flgD Cell envelope K02389 flgD; flagellar basal-body rod modification protein FlgD D flgE Cellular processes K02390 flgE; flagellar hook protein FlgE D flgF Cellular processes K02391 flgF; flagellar basal-body rod protein FlgF D flgG Cellular processes K02392 flgG; flagellar basal-body rod protein FlgG D flgH Cellular processes K02393 flgH; flagellar L-ring protein FlgH D flgI Cellular processes K02394 flgI; flagellar P-ring protein FlgI D flgK Cellular processes K02396 flgK; flagellar hook-associated protein 1 D flgL Cellular processes K02397 flgL; flagellar hook-associated protein 3 FlgL D fliC Cellular processes K02406 fliC; flagellin D fliD Cellular processes K02407 fliD; flagellar hook-associated protein 2 D fliS Cellular processes K02422 fliS; flagellar secretion chaperone FliS D motA Cellular processes K02556 motA; chemotaxis protein MotA D motB Cellular processes K02557 motB; chemotaxis protein MotB D flgN Cell envelope K02399 flgN; flagellar biosynthesis protein FlgN D rpoD Transcription K03086 rpoD; RNA polymerase primary sigma factor D flhD Cellular processes K02403 flhD; flagellar transcriptional activator FlhD D flhC Cellular processes K02402 flhC; flagellar transcriptional activator FlhC D fliA Cellular processes K02405 fliA; RNA polymerase sigma factor FliA C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D eno Energy metabolism K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04981 Folate transport and metabolism [PATH:wbr04981] D folA Biosynthesis of cofactors, prosthetic groups, and carrier K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D glyA Amino acid biosynthesis K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D thyA Purines, pyrimidines, nucleosides, and nucleotides K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation C 04382 Cornified envelope formation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:wbr01501] D mrdA Cell envelope K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D ftsI Cellular processes K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] C 01502 Vancomycin resistance [PATH:wbr01502] D ddlA Cell envelope K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D dadX Cell envelope K01775 alr; alanine racemase [EC:5.1.1.1] D murF Cell envelope K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D mraY Cell envelope K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D murG Cell envelope K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:wbr01503] D b2254 Cell envelope K10012 arnC; undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [EC:2.4.2.53] D b2255 Protein synthesis K10011 arnA; UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305] D b2256 Hypothetical proteins K13014 arnD; undecaprenyl phosphate-alpha-L-ara4FN deformylase [EC:3.5.1.-] D b2257 Unclassified K07264 arnT; 4-amino-4-deoxy-L-arabinose transferase [EC:2.4.2.43] D cpxR Regulatory functions K07662 cpxR; two-component system, OmpR family, response regulator CpxR D b2817 Cell envelope K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D dsbA Protein fate K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] D lpxA Cell envelope K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:wbr01000] C 01001 Protein kinases C 01009 Protein phosphatases and associated proteins [BR:wbr01009] D htpG Protein fate K04079 HSP90A; molecular chaperone HtpG C 01002 Peptidases and inhibitors [BR:wbr01002] D lspA Protein fate K03101 lspA; signal peptidase II [EC:3.4.23.36] D guaA Purines, pyrimidines, nucleosides, and nucleotides K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D purF Purines, pyrimidines, nucleosides, and nucleotides K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D glmS Central intermediary metabolism K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D asnB Amino acid biosynthesis K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D ybiS Hypothetical proteins K19235 ybiS; L,D-transpeptidase YbiS D prlC Protein fate K01414 prlC; oligopeptidase A [EC:3.4.24.70] D pepA Protein fate K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D dapE Amino acid biosynthesis K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D yebA Cell envelope K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] D map Protein fate K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D pepP Protein fate K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D hflB Cellular processes K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D htpX Protein fate K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D yaeL Protein fate K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D degQ Protein fate K04772 degQ; serine protease DegQ [EC:3.4.21.-] D dacA Cell envelope K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D clpP Protein fate K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D lon Protein fate K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D lepB Protein fate K03100 lepB; signal peptidase I [EC:3.4.21.89] D sppA Protein fate K04773 sppA; protease IV [EC:3.4.21.-] D hslV Protein fate K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] D hflC Protein fate K04087 hflC; modulator of FtsH protease HflC D hflK Protein fate K04088 hflK; modulator of FtsH protease HflK C 01003 Glycosyltransferases [BR:wbr01003] D mrcB Cell envelope K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] D ftsW Cellular processes K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] D mrdB Cell envelope K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28] D mdoH Cellular processes K03669 mdoH; membrane glycosyltransferase [EC:2.4.1.-] C 01005 Lipopolysaccharide biosynthesis proteins [BR:wbr01005] D lpxA Cell envelope K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D lpxB Cell envelope K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D lpxC Cell envelope K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] D lpxD Cell envelope K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D ybbF Hypothetical proteins K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D ycaH Cell envelope K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D kdtA Cell envelope K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D b2257 Unclassified K07264 arnT; 4-amino-4-deoxy-L-arabinose transferase [EC:2.4.2.43] D kdsA Cell envelope K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D kdsB Cell envelope K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D yrbH Energy metabolism K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:wbr01011] D murA Cell envelope K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D murB Cell envelope K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D murC Cell envelope K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D murD Cell envelope K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D murE Cell envelope K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D ddlA Cell envelope K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D dadX Cell envelope K01775 alr; alanine racemase [EC:5.1.1.1] D murI Cell envelope K01776 murI; glutamate racemase [EC:5.1.1.3] D mraY Cell envelope K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D murG Cell envelope K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D bacA Cellular processes K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D mviN Cellular processes K03980 murJ; putative peptidoglycan lipid II flippase D mrcB Cell envelope K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] D mrdA Cell envelope K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D ftsI Cellular processes K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D dacA Cell envelope K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D ftsW Cellular processes K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] D mrdB Cell envelope K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28] D ybiS Hypothetical proteins K19235 ybiS; L,D-transpeptidase YbiS D yebA Cell envelope K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] D mltC Cell envelope K08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29] D yceG Hypothetical proteins K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] D b2817 Cell envelope K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D lpp Cell envelope K06078 lpp; murein lipoprotein C 01004 Lipid biosynthesis proteins [BR:wbr01004] D fabD Fatty acid and phospholipid metabolism K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D fabB Fatty acid and phospholipid metabolism K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D fabG Fatty acid and phospholipid metabolism K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D fabA Fatty acid and phospholipid metabolism K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D fabI Fatty acid and phospholipid metabolism K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D plsB Fatty acid and phospholipid metabolism K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] D plsC Fatty acid and phospholipid metabolism K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:wbr01006] D ispA Biosynthesis of cofactors, prosthetic groups, and carrier K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D ispB Biosynthesis of cofactors, prosthetic groups, and carrier K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D yaeS Biosynthesis of cofactors, prosthetic groups, and carrier K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D miaA Protein synthesis K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D ubiA Biosynthesis of cofactors, prosthetic groups, and carrier K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D cyoE Energy metabolism K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:wbr01007] D gltX Protein synthesis K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D glnS Protein synthesis K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D tyrS Protein synthesis K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D trpS Protein synthesis K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D cysS Protein synthesis K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D argS Protein synthesis K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D metG Protein synthesis K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D ileS Protein synthesis K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D valS Protein synthesis K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D leuS Protein synthesis K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D lysS Protein synthesis K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D aspS Protein synthesis K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D asnS Protein synthesis K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D hisS Protein synthesis K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D glyQ Protein synthesis K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D glyS Protein synthesis K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D serS Protein synthesis K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D proS Protein synthesis K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D thrS Protein synthesis K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D alaS Protein synthesis K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D pheS Protein synthesis K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D pheT Protein synthesis K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D aspC Amino acid biosynthesis K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] D bioF Biosynthesis of cofactors, prosthetic groups, and carrier K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D bioA Biosynthesis of cofactors, prosthetic groups, and carrier K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D hemL Biosynthesis of cofactors, prosthetic groups, and carrier K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D serC Amino acid biosynthesis K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D wecE Cell envelope K02805 wecE; dTDP-4-amino-4,6-dideoxygalactose transaminase [EC:2.6.1.59] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:wbr00194] D atpC Energy metabolism K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D atpD Energy metabolism K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D atpG Energy metabolism K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D atpA Energy metabolism K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D atpH Energy metabolism K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D atpF Energy metabolism K02109 ATPF0B; F-type H+-transporting ATPase subunit b D atpE Energy metabolism K02110 ATPF0C; F-type H+-transporting ATPase subunit c D atpB Energy metabolism K02108 ATPF0A; F-type H+-transporting ATPase subunit a B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:wbr03000] D slyA Cellular processes K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin D birA Regulatory functions K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D putA Energy metabolism K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D yqgE Hypothetical proteins K07735 algH; putative transcriptional regulator C 03021 Transcription machinery [BR:wbr03021] D rpoA Transcription K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D rpoB Transcription K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D rpoC Transcription K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D rpoZ Transcription K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D rpoD Transcription K03086 rpoD; RNA polymerase primary sigma factor D rpoH Protein fate K03089 rpoH; RNA polymerase sigma-32 factor D fliA Cellular processes K02405 fliA; RNA polymerase sigma factor FliA D nusA Transcription K02600 nusA; transcription termination/antitermination protein NusA D nusB Transcription K03625 nusB; transcription antitermination protein NusB D nusG Transcription K02601 nusG; transcription termination/antitermination protein NusG D greA Transcription K03624 greA; transcription elongation factor GreA D rho Transcription K03628 rho; transcription termination factor Rho C 03019 Messenger RNA biogenesis [BR:wbr03019] D rne Transcription K08300 rne; ribonuclease E [EC:3.1.26.12] D rnc Transcription K03685 rnc; ribonuclease III [EC:3.1.26.3] D yjeR Transcription K13288 orn; oligoribonuclease [EC:3.1.-.-] D deaD Transcription K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D eno Energy metabolism K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D pnp Transcription K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D rho Transcription K03628 rho; transcription termination factor Rho D dnaK Protein fate K04043 dnaK; molecular chaperone DnaK D mopA Protein fate K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D hfq Regulatory functions K03666 hfq; host factor-I protein C 03041 Spliceosome C 03011 Ribosome [BR:wbr03011] D rpsA Protein synthesis K02945 RP-S1; small subunit ribosomal protein S1 D rpsB Protein synthesis K02967 RP-S2; small subunit ribosomal protein S2 D rpsC Protein synthesis K02982 RP-S3; small subunit ribosomal protein S3 D rpsD Protein synthesis K02986 RP-S4; small subunit ribosomal protein S4 D rpsE Protein synthesis K02988 RP-S5; small subunit ribosomal protein S5 D rpsF Protein synthesis K02990 RP-S6; small subunit ribosomal protein S6 D rpsG Protein synthesis K02992 RP-S7; small subunit ribosomal protein S7 D rpsH Protein synthesis K02994 RP-S8; small subunit ribosomal protein S8 D rpsI Protein synthesis K02996 RP-S9; small subunit ribosomal protein S9 D rpsJ Protein synthesis K02946 RP-S10; small subunit ribosomal protein S10 D rpsK Protein synthesis K02948 RP-S11; small subunit ribosomal protein S11 D rpsL Protein synthesis K02950 RP-S12; small subunit ribosomal protein S12 D rpsM Protein synthesis K02952 RP-S13; small subunit ribosomal protein S13 D rpsN Protein synthesis K02954 RP-S14; small subunit ribosomal protein S14 D rpsO Protein synthesis K02956 RP-S15; small subunit ribosomal protein S15 D rpsP Protein synthesis K02959 RP-S16; small subunit ribosomal protein S16 D rpsQ Protein synthesis K02961 RP-S17; small subunit ribosomal protein S17 D rpsR Protein synthesis K02963 RP-S18; small subunit ribosomal protein S18 D rpsS Protein synthesis K02965 RP-S19; small subunit ribosomal protein S19 D rpsT Protein synthesis K02968 RP-S20; small subunit ribosomal protein S20 D rpsU Protein synthesis K02970 RP-S21; small subunit ribosomal protein S21 D rplA Protein synthesis K02863 RP-L1; large subunit ribosomal protein L1 D rplB Protein synthesis K02886 RP-L2; large subunit ribosomal protein L2 D rplC Protein synthesis K02906 RP-L3; large subunit ribosomal protein L3 D rplD Protein synthesis K02926 RP-L4; large subunit ribosomal protein L4 D rplE Protein synthesis K02931 RP-L5; large subunit ribosomal protein L5 D rplF Protein synthesis K02933 RP-L6; large subunit ribosomal protein L6 D rplI Protein synthesis K02939 RP-L9; large subunit ribosomal protein L9 D rplJ Protein synthesis K02864 RP-L10; large subunit ribosomal protein L10 D rplK Protein synthesis K02867 RP-L11; large subunit ribosomal protein L11 D rplL Protein synthesis K02935 RP-L7; large subunit ribosomal protein L7/L12 D rplM Protein synthesis K02871 RP-L13; large subunit ribosomal protein L13 D rplN Protein synthesis K02874 RP-L14; large subunit ribosomal protein L14 D rplO Protein synthesis K02876 RP-L15; large subunit ribosomal protein L15 D rplP Protein synthesis K02878 RP-L16; large subunit ribosomal protein L16 D rplQ Protein synthesis K02879 RP-L17; large subunit ribosomal protein L17 D rplR Protein synthesis K02881 RP-L18; large subunit ribosomal protein L18 D rplS Protein synthesis K02884 RP-L19; large subunit ribosomal protein L19 D rplT Protein synthesis K02887 RP-L20; large subunit ribosomal protein L20 D rplU Protein synthesis K02888 RP-L21; large subunit ribosomal protein L21 D rplV Protein synthesis K02890 RP-L22; large subunit ribosomal protein L22 D rplW Protein synthesis K02892 RP-L23; large subunit ribosomal protein L23 D rplX Protein synthesis K02895 RP-L24; large subunit ribosomal protein L24 D rpmA Protein synthesis K02899 RP-L27; large subunit ribosomal protein L27 D rpmB Protein synthesis K02902 RP-L28; large subunit ribosomal protein L28 D rpmC Protein synthesis K02904 RP-L29; large subunit ribosomal protein L29 D rpmD Protein synthesis K02907 RP-L30; large subunit ribosomal protein L30 D rpmE Protein synthesis K02909 RP-L31; large subunit ribosomal protein L31 D rpmF Protein synthesis K02911 RP-L32; large subunit ribosomal protein L32 D rpmG Protein synthesis K02913 RP-L33; large subunit ribosomal protein L33 D rpmH Protein synthesis K02914 RP-L34; large subunit ribosomal protein L34 D rpmI Protein synthesis K02916 RP-L35; large subunit ribosomal protein L35 D rpmJ Protein synthesis K02919 RP-L36; large subunit ribosomal protein L36 D rrsH-1 rrsH K01977 16SrRNA; 16S ribosomal RNA D rrsH-2 rrsH K01977 16SrRNA; 16S ribosomal RNA D rrlB-1 rrlB K01980 23SrRNA; 23S ribosomal RNA D rrlB-2 rrlB K01980 23SrRNA; 23S ribosomal RNA D rrfA-1 rrfA K01985 5SrRNA; 5S ribosomal RNA D rrfA-2 rrfA K01985 5SrRNA; 5S ribosomal RNA C 03009 Ribosome biogenesis [BR:wbr03009] D rnc Transcription K03685 rnc; ribonuclease III [EC:3.1.26.3] D yjeR Transcription K13288 orn; oligoribonuclease [EC:3.1.-.-] D yhbZ Unknown function K03979 obgE; GTPase [EC:3.6.5.-] D nusA Transcription K02600 nusA; transcription termination/antitermination protein NusA D nusB Transcription K03625 nusB; transcription antitermination protein NusB D nusG Transcription K02601 nusG; transcription termination/antitermination protein NusG D ksgA Protein synthesis K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D yhhF Hypothetical proteins K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D yggJ Hypothetical proteins K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D yabC Hypothetical proteins K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D yraL Hypothetical proteins K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D yjfH Protein synthesis K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D ftsJ Protein synthesis K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D yfgB Hypothetical proteins K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D rluD Protein synthesis K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D yfcB DNA metabolism K07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298] D rne Transcription K08300 rne; ribonuclease E [EC:3.1.26.12] D yqgF Hypothetical proteins K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D deaD Transcription K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D b2511 Unknown function K03977 engA; GTPase D yrdC Unknown function K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D rbfA Transcription K02834 rbfA; ribosome-binding factor A D ybeY Hypothetical proteins K07042 ybeY; probable rRNA maturation factor D ychF Hypothetical proteins K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:wbr03016] D cca Transcription K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D gltX Protein synthesis K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D proS Protein synthesis K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D ileS Protein synthesis K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D leuS Protein synthesis K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D metG Protein synthesis K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D glnS Protein synthesis K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D argS Protein synthesis K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D lysS Protein synthesis K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D aspS Protein synthesis K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D alaS Protein synthesis K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D asnS Protein synthesis K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D thrS Protein synthesis K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D serS Protein synthesis K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D cysS Protein synthesis K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D valS Protein synthesis K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D hisS Protein synthesis K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D pheS Protein synthesis K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D pheT Protein synthesis K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D tyrS Protein synthesis K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D trpS Protein synthesis K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D ycfF Unknown function K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D truA Protein synthesis K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D truB Protein synthesis K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D yfhO Biosynthesis of cofactors, prosthetic groups, and carrier K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D yrdC Unknown function K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D miaA Protein synthesis K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D thdF Cellular processes K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D gidA Unknown function K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D rnt Transcription K03683 rnt; ribonuclease T [EC:3.1.13.-] D glyQ Protein synthesis K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D glyS Protein synthesis K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D yfhC Unknown function K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D ycfB Protein synthesis K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D ygfZ Hypothetical proteins K06980 ygfZ; tRNA-modifying protein YgfZ D mesJ Cellular processes K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D yeaZ Hypothetical proteins K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D ygjD Protein fate K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D pnp Transcription K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:wbr03012] D infB Protein synthesis K02519 infB; translation initiation factor IF-2 D infC Protein synthesis K02520 infC; translation initiation factor IF-3 D tsf Protein synthesis K02357 tsf; elongation factor Ts D tufA Protein synthesis K02358 tuf; elongation factor Tu D fusA Protein synthesis K02355 fusA; elongation factor G D prfA Protein synthesis K02835 prfA; peptide chain release factor 1 D frr Protein synthesis K02838 frr; ribosome recycling factor D hemK Biosynthesis of cofactors, prosthetic groups, and carrier K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D pth Protein synthesis K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D infA Protein synthesis K02518 infA; translation initiation factor IF-1 D efp Protein synthesis K02356 efp; elongation factor P D prfB Protein synthesis K02836 prfB; peptide chain release factor 2 C 03110 Chaperones and folding catalysts [BR:wbr03110] D clpX Protein fate K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D hslU Cellular processes K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU D htpG Protein fate K04079 HSP90A; molecular chaperone HtpG D dnaK Protein fate K04043 dnaK; molecular chaperone DnaK D mopA Protein fate K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D dnaJ Protein fate K03686 dnaJ; molecular chaperone DnaJ D grpE Protein fate K03687 GRPE; molecular chaperone GrpE D mopB Protein fate K04078 groES; chaperonin GroES D hflB Cellular processes K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D atpB Energy metabolism K02108 ATPF0A; F-type H+-transporting ATPase subunit a D ppiD Hypothetical proteins K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] D surA Protein fate K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8] D trxA Energy metabolism K03671 TXN; thioredoxin D grxC Biosynthesis of cofactors, prosthetic groups, and carrier K03676 grxC; glutaredoxin 3 D ydhD Hypothetical proteins K07390 grxD; monothiol glutaredoxin D dsbA Protein fate K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] C 04131 Membrane trafficking [BR:wbr04131] D ndk Purines, pyrimidines, nucleosides, and nucleotides K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D gapA Energy metabolism K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D gpmA Energy metabolism K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D pykA Energy metabolism K00873 PK; pyruvate kinase [EC:2.7.1.40] D htpG Protein fate K04079 HSP90A; molecular chaperone HtpG C 04121 Ubiquitin system [BR:wbr04121] C 03051 Proteasome [BR:wbr03051] D htpG Protein fate K04079 HSP90A; molecular chaperone HtpG C 03032 DNA replication proteins [BR:wbr03032] D rnhA Transcription K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D hupA Protein synthesis K05787 hupA; DNA-binding protein HU-alpha D dnaB DNA metabolism K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D dnaG DNA metabolism K02316 dnaG; DNA primase [EC:2.7.7.101] D ssb DNA metabolism K03111 ssb; single-strand DNA-binding protein D dnaE DNA metabolism K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D dnaN DNA metabolism K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D holA DNA metabolism K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D holB DNA metabolism K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D dnaQ DNA metabolism K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D dnaX DNA metabolism K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D holE Hypothetical proteins K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] D lig DNA metabolism K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D gyrA DNA metabolism K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D gyrB DNA metabolism K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] C 03036 Chromosome and associated proteins [BR:wbr03036] D rnc Transcription K03685 rnc; ribonuclease III [EC:3.1.26.3] D hns DNA metabolism K03746 hns; DNA-binding protein H-NS D hupA Protein synthesis K05787 hupA; DNA-binding protein HU-alpha D yccV Hypothetical proteins K11940 hspQ; heat shock protein HspQ D hfq Regulatory functions K03666 hfq; host factor-I protein D ftsA Cellular processes K03590 ftsA; cell division protein FtsA D b2748 Hypothetical proteins K05589 ftsB; cell division protein FtsB D ftsI Cellular processes K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D ftsK Cellular processes K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D ftsL Cellular processes K03586 ftsL; cell division protein FtsL D ftsQ Cellular processes K03589 ftsQ; cell division protein FtsQ D ftsW Cellular processes K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] D ftsZ Cellular processes K03531 ftsZ; cell division protein FtsZ D ygfE Hypothetical proteins K09888 zapA; cell division protein ZapA D yhcM Hypothetical proteins K06916 zapE; cell division protein ZapE D b2817 Cell envelope K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D minC Cellular processes K03610 minC; septum site-determining protein MinC D minD Cellular processes K03609 minD; septum site-determining protein MinD D minE Cellular processes K03608 minE; cell division topological specificity factor D mreB Cell envelope K03569 mreB; rod shape-determining protein MreB and related proteins D mreC Cell envelope K03570 mreC; rod shape-determining protein MreC D mreD Cell envelope K03571 mreD; rod shape-determining protein MreD D mrdB Cell envelope K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28] D gidA Unknown function K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D yihA Unknown function K03978 engB; GTP-binding protein C 03400 DNA repair and recombination proteins [BR:wbr03400] D phrB DNA metabolism K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D ung DNA metabolism K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D nth DNA metabolism K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D dut Purines, pyrimidines, nucleosides, and nucleotides K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D xthA DNA metabolism K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] D recJ DNA metabolism K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D lig DNA metabolism K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D uvrD DNA metabolism K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D rpoB Transcription K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D rpoC Transcription K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D rpoA Transcription K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D rpoZ Transcription K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D mfd DNA metabolism K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D dnaE DNA metabolism K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D dnaN DNA metabolism K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D holA DNA metabolism K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D holB DNA metabolism K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D dnaQ DNA metabolism K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D dnaX DNA metabolism K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D holE Hypothetical proteins K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] D ssb DNA metabolism K03111 ssb; single-strand DNA-binding protein D recB DNA metabolism K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] D recC DNA metabolism K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] D recD DNA metabolism K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D recA DNA metabolism K03553 recA; recombination protein RecA D ruvC DNA metabolism K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D gyrA DNA metabolism K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D gyrB DNA metabolism K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D hupA Protein synthesis K05787 hupA; DNA-binding protein HU-alpha D hns DNA metabolism K03746 hns; DNA-binding protein H-NS D nrdE Purines, pyrimidines, nucleosides, and nucleotides K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D nrdF Purines, pyrimidines, nucleosides, and nucleotides K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C 03029 Mitochondrial biogenesis [BR:wbr03029] D infB Protein synthesis K02519 infB; translation initiation factor IF-2 D infC Protein synthesis K02520 infC; translation initiation factor IF-3 D tsf Protein synthesis K02357 tsf; elongation factor Ts D tufA Protein synthesis K02358 tuf; elongation factor Tu D fusA Protein synthesis K02355 fusA; elongation factor G D tyrS Protein synthesis K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D leuS Protein synthesis K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D aspS Protein synthesis K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D argS Protein synthesis K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D ssb DNA metabolism K03111 ssb; single-strand DNA-binding protein D yaeT Cell envelope K07277 SAM50; outer membrane protein insertion porin family D dnaK Protein fate K04043 dnaK; molecular chaperone DnaK D grpE Protein fate K03687 GRPE; molecular chaperone GrpE D mopA Protein fate K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D mopB Protein fate K04078 groES; chaperonin GroES D dnaJ Protein fate K03686 dnaJ; molecular chaperone DnaJ D yfhO Biosynthesis of cofactors, prosthetic groups, and carrier K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ydhD Hypothetical proteins K07390 grxD; monothiol glutaredoxin D cyoE Energy metabolism K02257 COX10; heme o synthase [EC:2.5.1.141] D yidC Unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase D htpG Protein fate K04079 HSP90A; molecular chaperone HtpG B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:wbr02000] D msbA Transport and binding proteins K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] D mdl Transport and binding proteins K18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump D mdlB Transport and binding proteins K18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump D fliY Cell envelope K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D gltJ Transport and binding proteins K02029 ABC.PA.P; polar amino acid transport system permease protein D gltK Transport and binding proteins K02029 ABC.PA.P; polar amino acid transport system permease protein D gltL Transport and binding proteins K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D yebI Cell envelope K09816 znuB; zinc transport system permease protein D yebM Transport and binding proteins K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D yjgP Hypothetical proteins K07091 lptF; lipopolysaccharide export system permease protein D yjgQ Hypothetical proteins K11720 lptG; lipopolysaccharide export system permease protein D yhbG Transport and binding proteins K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D ycfU Hypothetical proteins K09808 lolC_E_F; lipoprotein-releasing system permease protein D ycfW Hypothetical proteins K09808 lolC_E_F; lipoprotein-releasing system permease protein D ycfV Transport and binding proteins K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D yadH Cellular processes K01992 ABC-2.P; ABC-2 type transport system permease protein D yadG Cellular processes K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ynhD Transport and binding proteins K09013 sufC; Fe-S cluster assembly ATP-binding protein D emrD Cellular processes K08154 emrD; MFS transporter, DHA1 family, 2-module integral membrane pump EmrD D yccA Cell envelope K19416 yccA; modulator of FtsH protease D yjeP Unknown function K22051 mscM; miniconductance mechanosensitive channel D motA Cellular processes K02556 motA; chemotaxis protein MotA D motB Cellular processes K02557 motB; chemotaxis protein MotB D tolQ Cellular processes K03562 tolQ; biopolymer transport protein TolQ D tolR Cellular processes K03560 tolR; biopolymer transport protein TolR D corA Transport and binding proteins K03284 corA; magnesium transporter D yaeT Cell envelope K07277 SAM50; outer membrane protein insertion porin family D yfiO Hypothetical proteins K05807 bamD; outer membrane protein assembly factor BamD D ytfM Hypothetical proteins K07278 tamA; translocation and assembly module TamA D ytfN Hypothetical proteins K09800 tamB; translocation and assembly module TamB D yrbK Hypothetical proteins K11719 lptC; lipopolysaccharide export system protein LptC D imp Cellular processes K04744 lptD; LPS-assembly protein D rlpB Cell envelope K03643 lptE; LPS-assembly lipoprotein D emrE Cellular processes K03297 emrE; small multidrug resistance pump D pitA Transport and binding proteins K16322 pit; low-affinity inorganic phosphate transporter D nhaA Transport and binding proteins K03313 nhaA; Na+:H+ antiporter, NhaA family D b1191 Unclassified K11105 cvrA; potassium/hydrogen antiporter D trkH Transport and binding proteins K03498 trkH; trk/ktr system potassium uptake protein D trkA Transport and binding proteins K03499 trkA; trk/ktr system potassium uptake protein D sdaC Transport and binding proteins K03837 sdaC; serine transporter D b2392 Unclassified K03322 mntH; manganese transport protein D mviN Cellular processes K03980 murJ; putative peptidoglycan lipid II flippase D kup Transport and binding proteins K03549 kup; KUP system potassium uptake protein D ydeB Hypothetical proteins K05595 marC; multiple antibiotic resistance protein D ftsW Cellular processes K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] D pal Cell envelope K03640 pal; peptidoglycan-associated lipoprotein D tolA Cellular processes K03646 tolA; colicin import membrane protein D tolB Cellular processes K03641 tolB; TolB protein D yraP Hypothetical proteins K28369 dolP; outer membrane lipoprotein DolP C 02044 Secretion system [BR:wbr02044] D flhA Cellular processes K02400 flhA; flagellar biosynthesis protein FlhA D flhB Cellular processes K02401 flhB; flagellar biosynthesis protein FlhB D fliF Cellular processes K02409 fliF; flagellar M-ring protein FliF D fliH Cellular processes K02411 fliH; flagellar assembly protein FliH D fliI Cellular processes K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D fliN Cellular processes K02417 fliN; flagellar motor switch protein FliN D fliO Cellular processes K02418 fliO; flagellar protein FliO/FliZ D fliP Cellular processes K02419 fliP; flagellar biosynthesis protein FliP D fliQ Cellular processes K02420 fliQ; flagellar biosynthesis protein FliQ D fliR Cellular processes K02421 fliR; flagellar biosynthesis protein FliR D secA Protein fate K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D secE Protein fate K03073 secE; preprotein translocase subunit SecE D secG Protein fate K03075 secG; preprotein translocase subunit SecG D prlA Protein fate K03076 secY; preprotein translocase subunit SecY D ffh Protein fate K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D ftsY Cellular processes K03110 ftsY; fused signal recognition particle receptor D yajC Protein fate K03210 yajC; preprotein translocase subunit YajC D yidC Unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins C 02022 Two-component system [BR:wbr02022] D cpxR Regulatory functions K07662 cpxR; two-component system, OmpR family, response regulator CpxR C 02035 Bacterial motility proteins [BR:wbr02035] D fliH Cellular processes K02411 fliH; flagellar assembly protein FliH D fliI Cellular processes K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D fliJ Cellular processes K02413 fliJ; flagellar protein FliJ D fliO Cellular processes K02418 fliO; flagellar protein FliO/FliZ D fliP Cellular processes K02419 fliP; flagellar biosynthesis protein FliP D fliQ Cellular processes K02420 fliQ; flagellar biosynthesis protein FliQ D fliR Cellular processes K02421 fliR; flagellar biosynthesis protein FliR D flhA Cellular processes K02400 flhA; flagellar biosynthesis protein FlhA D flhB Cellular processes K02401 flhB; flagellar biosynthesis protein FlhB D fliG Cellular processes K02410 fliG; flagellar motor switch protein FliG D fliM Cellular processes K02416 fliM; flagellar motor switch protein FliM D fliN Cellular processes K02417 fliN; flagellar motor switch protein FliN D fliF Cellular processes K02409 fliF; flagellar M-ring protein FliF D flgI Cellular processes K02394 flgI; flagellar P-ring protein FlgI D flgA Cellular processes K02386 flgA; flagellar basal body P-ring formation protein FlgA D flgH Cellular processes K02393 flgH; flagellar L-ring protein FlgH D fliL Hypothetical proteins K02415 fliL; flagellar protein FliL D fliE Cellular processes K02408 fliE; flagellar hook-basal body complex protein FliE D flgB Cell envelope K02387 flgB; flagellar basal-body rod protein FlgB D flgC Cell envelope K02388 flgC; flagellar basal-body rod protein FlgC D flgD Cell envelope K02389 flgD; flagellar basal-body rod modification protein FlgD D flgF Cellular processes K02391 flgF; flagellar basal-body rod protein FlgF D flgG Cellular processes K02392 flgG; flagellar basal-body rod protein FlgG D flgE Cellular processes K02390 flgE; flagellar hook protein FlgE D flgK Cellular processes K02396 flgK; flagellar hook-associated protein 1 D flgL Cellular processes K02397 flgL; flagellar hook-associated protein 3 FlgL D flgN Cell envelope K02399 flgN; flagellar biosynthesis protein FlgN D fliC Cellular processes K02406 fliC; flagellin D fliD Cellular processes K02407 fliD; flagellar hook-associated protein 2 D fliS Cellular processes K02422 fliS; flagellar secretion chaperone FliS D flhD Cellular processes K02403 flhD; flagellar transcriptional activator FlhD D flhC Cellular processes K02402 flhC; flagellar transcriptional activator FlhC D fliA Cellular processes K02405 fliA; RNA polymerase sigma factor FliA D motA Cellular processes K02556 motA; chemotaxis protein MotA D motB Cellular processes K02557 motB; chemotaxis protein MotB C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:wbr04812] D mreB Cell envelope K03569 mreB; rod shape-determining protein MreB and related proteins D ftsZ Cellular processes K03531 ftsZ; cell division protein FtsZ D ftsA Cellular processes K03590 ftsA; cell division protein FtsA D minC Cellular processes K03610 minC; septum site-determining protein MinC D minD Cellular processes K03609 minD; septum site-determining protein MinD D minE Cellular processes K03608 minE; cell division topological specificity factor C 04147 Exosome [BR:wbr04147] D htpG Protein fate K04079 HSP90A; molecular chaperone HtpG D eno Energy metabolism K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D gapA Energy metabolism K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D pgk Energy metabolism K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D pykA Energy metabolism K00873 PK; pyruvate kinase [EC:2.7.1.40] D ahpC Cellular processes K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D mopA Protein fate K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D dnaK Protein fate K04043 dnaK; molecular chaperone DnaK D pgi Energy metabolism K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D guaB Purines, pyrimidines, nucleosides, and nucleotides K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D tufA Protein synthesis K02358 tuf; elongation factor Tu D ycfF Unknown function K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D adk Purines, pyrimidines, nucleosides, and nucleotides K00939 adk; adenylate kinase [EC:2.7.4.3] D fbp Energy metabolism K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D glnA Amino acid biosynthesis K01915 glnA; glutamine synthetase [EC:6.3.1.2] D hemB Biosynthesis of cofactors, prosthetic groups, and carrier K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D purH Purines, pyrimidines, nucleosides, and nucleotides K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D lpdA Energy metabolism K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D tpiA Energy metabolism K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D gpmA Energy metabolism K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:wbr02048] D ftsZ Cellular processes K03531 ftsZ; cell division protein FtsZ D mreB Cell envelope K03569 mreB; rod shape-determining protein MreB and related proteins D gltX Protein synthesis K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D ygfY Hypothetical proteins K09159 cptB; antitoxin CptB D hha Protein fate K05839 hha; haemolysin expression modulating protein D yfhO Biosynthesis of cofactors, prosthetic groups, and carrier K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:wbr03100] D ala-GGC ala-GGC K14218 tRNA-Ala; tRNA Ala D ala-TGC ala-TGC K14218 tRNA-Ala; tRNA Ala D arg-ACG arg-ACG K14219 tRNA-Arg; tRNA Arg D arg-CCG arg-CCG K14219 tRNA-Arg; tRNA Arg D arg-TCT arg-TCT K14219 tRNA-Arg; tRNA Arg D asn-GTT asn-GTT K14220 tRNA-Asn; tRNA Asn D asp-GTC asp-GTC K14221 tRNA-Asp; tRNA Asp D cys-GCA cys-GCA K14222 tRNA-Cys; tRNA Cys D gln-TTG gln-TTG K14223 tRNA-Gln; tRNA Gln D glu-TTC-1 glu-TTC K14224 tRNA-Glu; tRNA Glu D glu-TTC-2 glu-TTC K14224 tRNA-Glu; tRNA Glu D gly-GCC gly-GCC K14225 tRNA-Gly; tRNA Gly D gly-TCC gly-TCC K14225 tRNA-Gly; tRNA Gly D his-GTG his-GTG K14226 tRNA-His; tRNA His D ile-GAT ile-GAT K14227 tRNA-Ile; tRNA Ile D leu-CAA leu-CAA K14228 tRNA-Leu; tRNA Leu D leu-GAG leu-GAG K14228 tRNA-Leu; tRNA Leu D leu-TAA leu-TAA K14228 tRNA-Leu; tRNA Leu D leu-TAG leu-TAG K14228 tRNA-Leu; tRNA Leu D lys-TTT lys-TTT K14229 tRNA-Lys; tRNA Lys D met-CAT-1 met-CAT K14230 tRNA-Met; tRNA Met D met-CAT-2 met-CAT K14230 tRNA-Met; tRNA Met D met-CAT-3 met-CAT K14230 tRNA-Met; tRNA Met D phe-GAA phe-GAA K14231 tRNA-Phe; tRNA Phe D pro-TGG pro-TGG K14232 tRNA-Pro; tRNA Pro D ser-GCT ser-GCT K14233 tRNA-Ser; tRNA Ser D ser-GGA ser-GGA K14233 tRNA-Ser; tRNA Ser D ser-TGA ser-TGA K14233 tRNA-Ser; tRNA Ser D thr-GGT thr-GGT K14234 tRNA-Thr; tRNA Thr D thr-TGT thr-TGT K14234 tRNA-Thr; tRNA Thr D trp-CCA trp-CCA K14235 tRNA-Trp; tRNA Trp D tyr-GTA tyr-GTA K14236 tRNA-Tyr; tRNA Tyr D val-GAC val-GAC K14237 tRNA-Val; tRNA Val D val-TAC val-TAC K14237 tRNA-Val; tRNA Val D rrsH-1 rrsH K01977 16SrRNA; 16S ribosomal RNA D rrsH-2 rrsH K01977 16SrRNA; 16S ribosomal RNA D rrlB-1 rrlB K01980 23SrRNA; 23S ribosomal RNA D rrlB-2 rrlB K01980 23SrRNA; 23S ribosomal RNA D rrfA-1 rrfA K01985 5SrRNA; 5S ribosomal RNA D rrfA-2 rrfA K01985 5SrRNA; 5S ribosomal RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D ftn Transport and binding proteins K02217 ftnA; ferritin [EC:1.16.3.2] D fpr Energy metabolism K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D lnt Protein fate K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D lgt Protein fate K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D ycfH Unknown function K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D def Protein fate K01462 PDF; peptide deformylase [EC:3.5.1.88] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D fldA Energy metabolism K03839 fldA; flavodoxin I C 99983 Lipid metabolism C 99984 Nucleotide metabolism D nrdI Purines, pyrimidines, nucleosides, and nucleotides K03647 nrdI; protein involved in ribonucleotide reduction C 99985 Amino acid metabolism D yggS Hypothetical proteins K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism D yigR Cellular processes K03688 ubiB; ubiquinone biosynthesis protein C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D cspE Cellular processes K03704 cspA; cold shock protein C 99974 Translation C 99975 Protein processing D tig Protein fate K03545 tig; trigger factor D smpB Protein synthesis K03664 smpB; SsrA-binding protein D yhgI Unknown function K07400 nfuA; Fe/S biogenesis protein NfuA C 99976 Replication and repair C 99979 Viral proteins C 99998 Others D ybaB Hypothetical proteins K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D brnQ Transport and binding proteins K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family C 99978 Cell growth C 99993 Cell motility C 99995 Signaling proteins C 99992 Structural proteins D lolA Protein fate K03634 lolA; outer membrane lipoprotein carrier protein D hemM Protein fate K02494 lolB; outer membrane lipoprotein LolB D hlpA Cell envelope K06142 hlpA; outer membrane protein D yfgA Unknown function K15539 rodZ; cytoskeleton protein RodZ C 99994 Others D cutA Cellular processes K03926 cutA; periplasmic divalent cation tolerance protein B B 09194 Poorly characterized C 99996 General function prediction only D cvpA Cellular processes K03558 cvpA; membrane protein required for colicin V production D yadR Unknown function K15724 erpA; iron-sulfur cluster insertion protein D ydiC Unknown function K05997 sufA; Fe-S cluster assembly protein SufA D ynhE Transport and binding proteins K09014 sufB; Fe-S cluster assembly protein SufB D ynhC Unknown function K09015 sufD; Fe-S cluster assembly protein SufD D b1728 Hypothetical proteins K07038 K07038; inner membrane protein D ynhA Hypothetical proteins K02426 sufE; cysteine desulfuration protein SufE D yceA Unclassified K07146 K07146; UPF0176 protein D damX Hypothetical proteins K03112 damX; DamX protein C 99997 Function unknown D ycaR Hypothetical proteins K09791 K09791; uncharacterized protein D yacG Hypothetical proteins K09862 K09862; uncharacterized protein D yhcB Hypothetical proteins K09908 K09908; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: October 2, 2025