+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Xanthomonas campestris pv. raphani</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    XCR_4278 cas; crispr-associated protein Cas1	K15342 cas1; CRISP-associated protein Cas1 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      XCR_4279 crispr-associated helicase Cas3	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
D      XCR_4280 csy; crispr-associated protein, Csy1 family	K19127 csy1; CRISPR-associated protein Csy1 
D      XCR_4281 csy; crispr-associated protein, Csy2 family	K19128 csy2; CRISPR-associated protein Csy2 
D      XCR_4282 csy; crispr-associated protein, Csy3 family	K19129 csy3; CRISPR-associated protein Csy3 
D      XCR_4283 csy; crispr-associated protein, Csy4 family	K19130 csy4; CRISPR-associated endonuclease Csy4 [EC:3.1.-.-] 
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    XCR_1277 type I restriction-modification system restriction subunit	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    XCR_1275 type I restriction-modification system specificity subunit	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    XCR_1274 type I restriction-modification system specificity subunit	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
B  Type III R-M system
B  Type IV R-M system
C    XCR_3098 McrB-related protein	K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-] 
C    XCR_3097 conserved hypothetical protein	K19147 mcrC; 5-methylcytosine-specific restriction enzyme subunit McrC 
C    XCR_1273 Mrr restriction endonuclease	K07448 mrr; restriction system protein 
C    XCR_4529 restriction endonuclease	K07448 mrr; restriction system protein 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
D      XCR_3449 conserved hypothetical protein	K19048 symE; toxic protein SymE 
D      XCR_2154 conserved hypothetical protein	K19048 symE; toxic protein SymE 
D      XCR_2156 conserved hypothetical protein	K19048 symE; toxic protein SymE 
D      XCR_3916 conserved hypothetical protein	K19048 symE; toxic protein SymE 
D      XCR_2692 conserved hypothetical protein	K19048 symE; toxic protein SymE 
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      XCR_2904 conserved domain protein	K07172 mazE; antitoxin MazE 
C    ChpB-ChpS
C    YhaV-PrlF
D      XCR_2114 transcriptional regulator, AbrB family protein	K19156 prlF; antitoxin PrlF 
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
D      XCR_0880 conserved hypothetical protein	K19163 ccdB; toxin CcdB 
D      XCR_0881 conserved hypothetical protein	K19164 ccdA; antitoxin CcdA 
C    ParE-ParD
D      XCR_1234 plasmid stabilization system protein, RelE-ParE family	K19092 parE1_3_4; toxin ParE1/3/4 
D      XCR_1233 putative addiction module antidote protein, family, putative	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
C    HigB-HigA
D      XCR_4538 higA; addiction module antidote protein, HigA family	K21498 higA-1; antitoxin HigA-1 
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      XCR_0898 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      XCR_3806 rod shape-determining protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      XCR_1665 parC; DNA topoisomerase IV, A subunit	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      XCR_1931 parE; DNA topoisomerase IV, B subunit	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      XCR_3043 gltX; glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      XCR_2393 conserved hypothetical protein	K19168 cptA; toxin CptA 
D      XCR_2394 TPR repeat region superfamily	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023