+D Chaperone KO
#
Chaperones and Folding Catalysts - Xenia sp. Carnegie-2017 (soft corals)
%
!
AHeat shock proteins
B HSP110
C 124445084 hypoxia up-regulated protein 1-like K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C 124445810 caseinolytic peptidase B protein homolog isoform X1 K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
C 124448752 LOW QUALITY PROTEIN: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C 124441029 heat shock protein HSP 90-beta-like K04079 HSP90A; molecular chaperone HtpG
C 124435197 LOW QUALITY PROTEIN: endoplasmin-like K09487 HSP90B; heat shock protein 90kDa beta
C 124445997 heat shock protein 75 kDa, mitochondrial-like isoform X1 K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C 124449825 heat shock cognate 71 kDa protein-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 124449826 heat shock cognate 71 kDa protein-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 124452687 LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 124452703 heat shock cognate 71 kDa protein-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 124447487 LOW QUALITY PROTEIN: 97 kDa heat shock protein-like K09489 HSPA4; heat shock 70kDa protein 4
C 124439244 LOW QUALITY PROTEIN: endoplasmic reticulum chaperone BiP-like K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C 124442471 heat shock 70 kDa protein 13-like K09491 STCH; stress 70 protein chaperone microsome-associated 60kDa protein
C 124444233 stress-70 protein, mitochondrial-like isoform X1 K04043 dnaK; molecular chaperone DnaK
C 124444235 stress-70 protein, mitochondrial-like isoform X1 K04043 dnaK; molecular chaperone DnaK
C 124444237 LOW QUALITY PROTEIN: stress-70 protein, mitochondrial-like K04043 dnaK; molecular chaperone DnaK
C 124444238 stress-70 protein, mitochondrial-like K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C 124437120 LOW QUALITY PROTEIN: uncharacterized protein LOC124437120 K09493 CCT1; T-complex protein 1 subunit alpha
C 124433480 LOW QUALITY PROTEIN: T-complex protein 1 subunit alpha-like K09493 CCT1; T-complex protein 1 subunit alpha
C 124439489 LOW QUALITY PROTEIN: T-complex protein 1 subunit beta-like K09494 CCT2; T-complex protein 1 subunit beta
C 124451444 T-complex protein 1 subunit gamma-like K09495 CCT3; T-complex protein 1 subunit gamma
C 124443094 LOW QUALITY PROTEIN: T-complex protein 1 subunit delta-like K09496 CCT4; T-complex protein 1 subunit delta
C 124439705 T-complex protein 1 subunit epsilon-like K09497 CCT5; T-complex protein 1 subunit epsilon
C 124435652 T-complex protein 1 subunit zeta-like K09498 CCT6; T-complex protein 1 subunit zeta
C 124435735 T-complex protein 1 subunit zeta-like K09498 CCT6; T-complex protein 1 subunit zeta
C 124444324 T-complex protein 1 subunit eta-like K09499 CCT7; T-complex protein 1 subunit eta
C 124443038 T-complex protein 1 subunit theta-like K09500 CCT8; T-complex protein 1 subunit theta
C 124440324 heat shock protein 60A-like K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C 124439541 LOW QUALITY PROTEIN: dnaJ homolog subfamily A member 1-like K09502 DNAJA1; DnaJ homolog subfamily A member 1
C 124436819 LOW QUALITY PROTEIN: dnaJ homolog subfamily A member 2-like K09503 DNAJA2; DnaJ homolog subfamily A member 2
C 124447237 dnaJ homolog subfamily A member 3, mitochondrial-like isoform X1 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 124447263 dnaJ homolog subfamily C member 21-like K09506 DNAJA5; DnaJ homolog subfamily A member 5
C 124445093 dnaJ homolog subfamily B member 1-like K09507 DNAJB1; DnaJ homolog subfamily B member 1
C 124441098 dnaJ homolog subfamily B member 1-like K09510 DNAJB4; DnaJ homolog subfamily B member 4
C 124441465 dnaJ homolog subfamily B member 4-like isoform X1 K09511 DNAJB5; DnaJ homolog subfamily B member 5
C 124451011 dnaJ homolog subfamily B member 6-like isoform X1 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 124445895 LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 9-like K09515 DNAJB9; DnaJ homolog subfamily B member 9
C 124452910 LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 11-like K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 124441931 dnaJ homolog subfamily B member 13-like K09519 DNAJB13; DnaJ homolog subfamily B member 13
C 124459352 dnaJ homolog subfamily B member 14-like K09520 DNAJB14; DnaJ homolog subfamily B member 14
C 124440355 dnaJ homolog subfamily C member 1-like K09521 DNAJC1; DnaJ homolog subfamily C member 1
C 124435389 dnaJ homolog subfamily C member 2-like isoform X1 K09522 DNAJC2; DnaJ homolog subfamily C member 2
C 124445078 dnaJ homolog subfamily C member 3-like K09523 DNAJC3; DnaJ homolog subfamily C member 3
C 124452902 dnaJ homolog subfamily C member 4-like isoform X1 K09524 DNAJC4; DnaJ homolog subfamily C member 4
C 124453048 dnaJ homolog subfamily C member 5-like isoform X1 K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 124453154 dnaJ homolog subfamily C member 7-like K09527 DNAJC7; DnaJ homolog subfamily C member 7
C 124441004 dnaJ homolog subfamily C member 8-like K09528 DNAJC8; DnaJ homolog subfamily C member 8
C 124439877 dnaJ homolog subfamily C member 9-like K09529 DNAJC9; DnaJ homolog subfamily C member 9
C 124453636 dnaJ homolog subfamily C member 10-like K09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]
C 124443704 dnaJ homolog subfamily C member 11-like K09531 DNAJC11; DnaJ homolog subfamily C member 11
C 124446819 J domain-containing protein-like K09532 DNAJC12; DnaJ homolog subfamily C member 12
C 124453014 LOW QUALITY PROTEIN: dnaJ homolog subfamily C member 13-like K09533 DNAJC13; DnaJ homolog subfamily C member 13
C 124456198 uncharacterized protein LOC124456198 isoform X1 K09534 DNAJC14; DnaJ homolog subfamily C member 14
C 124438587 mitochondrial import inner membrane translocase subunit TIM14-like K09535 DNAJC15; DnaJ homolog subfamily C member 15
C 124444424 LOW QUALITY PROTEIN: dnaJ homolog subfamily C member 16-like K09536 DNAJC16; DnaJ homolog subfamily C member 16
C 124441516 dnaJ homolog subfamily C member 17-like isoform X1 K09537 DNAJC17; DnaJ homolog subfamily C member 17
C 124452627 dnaJ homolog subfamily C member 22-like K19370 DNAJC22; DnaJ homolog subfamily C member 22
C 124443197 translocation protein SEC63 homolog K09540 SEC63; translocation protein SEC63
C 124452605 dnaJ homolog subfamily C member 25-like K19371 DNAJC25; DnaJ homolog subfamily C member 25
C 124452696 dnaJ homolog subfamily C member 27-like isoform X1 K19372 DNAJC27; DnaJ homolog subfamily C member 27
C 124452939 dnaJ homolog subfamily C member 27-like K19372 DNAJC27; DnaJ homolog subfamily C member 27
C 124439920 uncharacterized protein LOC124439920 K19374 DNAJC30; DnaJ homolog subfamily C member 30
B HSP33
B HSP24
B HSP20
C 124443063 LOW QUALITY PROTEIN: uncharacterized protein LOC124443063 K09545 HSPB6; heat shock protein beta-6
C 124436428 intraflagellar transport protein 25 homolog isoform X1 K19369 HSPB11; heat shock protein beta-11
B HSP15
B HSP10
C 124440208 10 kDa heat shock protein, mitochondrial-like K04078 groES; chaperonin GroES
B GimC
C 124453126 prefoldin subunit 1-like K09548 PFDN1; prefoldin subunit 1
C 124445319 prefoldin subunit 2-like isoform X1 K09549 PFDN2; prefoldin subunit 2
C 124436752 prefoldin subunit 4-like K09550 PFDN4; prefoldin subunit 4
C 124440000 prefoldin subunit 5-like K04797 pfdA; prefoldin alpha subunit
C 124438989 prefoldin subunit 6-like K04798 pfdB; prefoldin beta subunit
#
AOther chaperones and cochaperones
B Calnexin / calreticulin
C 124445393 calnexin-like K08054 CANX; calnexin
B DegP / HtrA
C 124444048 LOW QUALITY PROTEIN: serine protease HTRA1-like K08785 HTRA3; HtrA serine peptidase 3 [EC:3.4.21.-]
B AAA proteases
C 124436749 LOW QUALITY PROTEIN: paraplegin-like K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C 124437034 LOW QUALITY PROTEIN: AFG3-like protein 2 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C 124443093 stress-induced-phosphoprotein 1-like K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C 124438665 hsp90 co-chaperone Cdc37-like K09554 CDC37; cell division cycle protein 37
B BAG
C 124445302 uncharacterized protein LOC124445302 K09555 BAG1; BCL2-associated athanogene 1
B Others
C 124446722 hsc70-interacting protein-like K09560 ST13; suppressor of tumorigenicity protein 13
C 124447921 E3 ubiquitin-protein ligase CHIP-like K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 124454238 hsp70-binding protein 1-like isoform X1 K09562 HSPBP1; hsp70-interacting protein
C 124444283 HSPB1-associated protein 1-like isoform X1 K19375 HSPBAP1; HSPB1-associated protein 1
C 124452959 protein Hikeshi-like K23327 HIKESHI; protein Hikeshi
C 124438105 NF-kappa-B inhibitor-like protein 1 K09256 NFKBIL1; NF-kappa-B inhibitor-like protein 1
C 124438868 NF-kappa-B inhibitor-like protein 1 K09256 NFKBIL1; NF-kappa-B inhibitor-like protein 1
C 124445416 B-cell lymphoma 3 protein-like K09258 BCL3; B-cell CLL/lymphoma 3 protein
C 124447087 NF-kappa-B inhibitor alpha-like isoform X1 K09258 BCL3; B-cell CLL/lymphoma 3 protein
C 124447088 B-cell lymphoma 3 protein homolog K09258 BCL3; B-cell CLL/lymphoma 3 protein
C 124442006 uncharacterized protein LOC124442006 K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 124443164 cysteine and histidine-rich domain-containing protein 1-like isoform X1 K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 124453691 prolyl 3-hydroxylase 2-like K22459 P3H2; procollagen-proline 3-dioxygenase 2 [EC:1.14.11.7]
C 124453182 protein N-lysine methyltransferase METTL21A-like isoform X1 K21804 METTL21A; protein N-lysine methyltransferase METTL21A [EC:2.1.1.-]
C 124444435 protein N-lysine methyltransferase METTL21A-like isoform X1 K21804 METTL21A; protein N-lysine methyltransferase METTL21A [EC:2.1.1.-]
C 124448320 probable methyltransferase-like protein 23 isoform X1 K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C 124433429 protein unc-45 homolog A-like isoform X1 K21991 UNC45; protein unc-45
C 124438223 torsin-1A-like K22990 TOR1; torsin-1
C 124438224 torsin-1A-like K22990 TOR1; torsin-1
C 124440850 small glutamine-rich tetratricopeptide repeat-containing protein beta-like K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C 124445016 tetratricopeptide repeat protein 1-like K24926 TTC1; tetratricopeptide repeat protein 1
C 124440827 LOW QUALITY PROTEIN: PAT complex subunit CCDC47-like K24962 CCDC47; PAT complex subunit CCDC47
C 124450694 LDLR chaperone boca-like isoform X1 K25366 MESD; LRP chaperone MESD
C 124442161 activator of 90 kDa heat shock protein ATPase homolog 1-like K26216 AHSA1; activator of Hsp90 ATPase protein 1
#
AIntramolecular chaperones
B Subtilisin family
C 124436466 LOW QUALITY PROTEIN: membrane-bound transcription factor site-1 protease-like K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C 124436935 proprotein convertase subtilisin/kexin type 4-like K01349 FURIN; furin [EC:3.4.21.75]
C 124443327 PC3-like endoprotease variant B K01349 FURIN; furin [EC:3.4.21.75]
C 124459460 LOW QUALITY PROTEIN: neuroendocrine convertase 1-like K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 124436810 neuroendocrine convertase 1-like K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 124446506 PC3-like endoprotease variant B K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 124443035 PC3-like endoprotease variant B isoform X1 K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 124459458 LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 6-like K08654 PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
C 124452299 proprotein convertase subtilisin/kexin type 7-like K08673 PCSK7; proprotein convertase subtilisin/kexin type 7 [EC:3.4.21.-]
C 124446780 tripeptidyl-peptidase 1-like K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C 124445257 LOW QUALITY PROTEIN: tripeptidyl-peptidase 2-like K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C 124433597 cathepsin B-like K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 124435866 procathepsin L-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 124435867 procathepsin L-like isoform X1 K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 124435869 procathepsin L-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 124436940 LOW QUALITY PROTEIN: procathepsin L-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 124437290 procathepsin L-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
C 124434223 zinc carboxypeptidase-like K08779 CPA1; carboxypeptidase A1 [EC:3.4.17.1]
C 124436910 lysosomal protective protein-like K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Others
C 124446129 beta-hexosaminidase subunit beta-like K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
#
AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D 124447490 peptidyl-prolyl cis-trans isomerase-like K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D 124454176 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 124454249 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 124454315 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 124454316 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 124455620 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 124446361 peptidyl-prolyl cis-trans isomerase D-like K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
D 124433467 peptidyl-prolyl cis-trans isomerase E-like isoform X1 K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D 124439757 peptidyl-prolyl cis-trans isomerase cyp11-like isoform X1 K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D 124444910 peptidyl-prolyl cis-trans isomerase H-like isoform X1 K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 124443557 peptidyl-prolyl cis-trans isomerase H-like isoform X1 K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 124438801 peptidyl-prolyl cis-trans isomerase-like 1 K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D 124435020 RING-type E3 ubiquitin-protein ligase PPIL2-like K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D 124439124 peptidyl-prolyl cis-trans isomerase-like 3 K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D 124442624 peptidyl-prolyl cis-trans isomerase-like 4 K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D 124441874 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase H-like K12739 PPIL6; peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8]
D 124439299 peptidylprolyl isomerase domain and WD repeat-containing protein 1-like K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D 124444874 spliceosome-associated protein CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 124446781 LOW QUALITY PROTEIN: E3 SUMO-protein ligase RanBP2-like K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D 124444265 peptidyl-prolyl cis-trans isomerase FKBP1A-like K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D 124441422 peptidyl-prolyl cis-trans isomerase FKBP2-like K09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]
D 124433499 FK506-binding protein 2-like K09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]
D 124440898 peptidyl-prolyl cis-trans isomerase FKBP3-like K09570 FKBP3; FK506-binding protein 3 [EC:5.2.1.8]
D 124439286 peptidyl-prolyl cis-trans isomerase FKBP65-like isoform X1 K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 124452248 peptidyl-prolyl cis-trans isomerase FKBP4-like K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 124434514 inactive peptidyl-prolyl cis-trans isomerase FKBP6-like isoform X1 K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D 124450252 peptidyl-prolyl cis-trans isomerase FKBP8-like isoform X1 K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
D 124452804 FK506-binding protein 2-like K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D 124457688 peptidyl-prolyl cis-trans isomerase FKBP14-like K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D 124437955 FK506-binding protein 15-like K17478 FKBP15; FK506-binding protein 15
C Parvulin
D 124438098 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1-like K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D 124446097 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4-like K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C 124452661 thioredoxin, mitochondrial-like K03671 TXN; thioredoxin
C 124452662 thioredoxin, mitochondrial-like K03671 TXN; thioredoxin
C 124442617 thioredoxin-like K03671 TXN; thioredoxin
C 124435673 glutaredoxin-like K03676 grxC; glutaredoxin 3
C 124433758 glutaredoxin-like K03676 grxC; glutaredoxin 3
C 124441490 glutaredoxin-related protein 5, mitochondrial-like K07390 grxD; monothiol glutaredoxin
C 124447749 protein disulfide-isomerase 2-like K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 124453898 protein disulfide-isomerase A3-like K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 124440622 protein disulfide-isomerase A4-like isoform X1 K09582 PDIA4; protein disulfide-isomerase A4 [EC:5.3.4.1]
C 124440821 protein disulfide-isomerase A5-like K09583 PDIA5; protein disulfide-isomerase A5 [EC:5.3.4.1]
C 124455337 protein disulfide-isomerase A6-like K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 124456803 thioredoxin domain-containing protein 5-like isoform X1 K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 124437650 protein disulfide-isomerase TMX3-like isoform X1 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
C 124435198 cysteine-rich with EGF-like domain protein 2-B K24335 CRELD; protein disulfide-isomerase [EC:5.3.4.1]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024