+D Transcription factors KO
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Transcription Factors - Xenorhabdus nematophila ATCC 19061
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
C AP-1(-like) components, Fos
C AP-1(-like) components, Maf
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
C CREB
C C/EBP-like factors
C bZIP/PAR
C Plant bZIP factors
C ZIP only
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
C Myogenic transcription factors
C Achaete-Scute
C Tal/Twist/Atonal/Hen, Lymphoid factors
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C Tal/Twist/Atonal/Hen, HEN
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
C Hairy, Fungal regulators
C Factors with PAS domain
C Yabby
C INO
C HLH domain only
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
C RF-X
C AP-2 (bHSH)
B Zinc finger
C Cys4 thyroid hormone receptor-like
C Cys4 hepatocyte nuclear factor 4-like
C Cys4 estrogen receptor-like
C Cys4 nerve growth factor IB-like
C Cys4 Fushi tarazu-F1-like
C Cys4 germ cell nuclear factor
C Cys4 Knirps/DAX1-like
C Cys4 GATA-factors
C Cys2His2 SP/KLF family and related proteins
C Cys2His2 GLI-like
C Cys2His2 Snail
C Cys2His2 BTB-ZF factors
C Cys2His2 BED
C Cys2His2 PRDM
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
C Cys2HisCys zinc factors
C Cys3His zinc factors
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D XNC1_3088 Dmt (fragment) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D XNC1_3668 dcm; DNA cytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D XNC1_p0056 putative DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
B Helix-turn-helix
C Homeo domain ANTP: HOXL
C Homeo domain ANTP: NKL
C Homeo domain Paired-related
C Homeo domain LIM
C Homeo domain POU
C Homeo domain SINE
C Homeo domain ZF
C Homeo domain CUT
C Homeo domain PROS
C Homeo domain TALE
C Homeo domain other
C Fork head/winged helix developmental regulators
C Fork head/winged helix tissue-specific regulators
C Fork head/winged helix cell cycle-controlling factors, E2F
C Fork head/winged helix cell cycle-controlling factors, DP
C Fork head/winged helix other regulators
C Stork head/winged helix factors
C Heat shock factors
C Tryptophan clusters Myb, Myb-factors
C Tryptophan clusters Myb, Myb-like factors
C Tryptophan clusters Ets-type
C Tryptophan clusters interferon-regulating factors
C TEA domain
C ARID
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
C RHR (Rel homology region) Ankyrin only
C RHR (Rel homology region) NF-AT
C STAT
C p53
C MADS-box regulators of differentiation, MEF-2
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
C SAND domain-containing proteins
C TATA-binding proteins
C HMG SOX
C HMG TCF-1
C HMG TOX
C HMG2-related
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
C Grainyhead
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
C Cold-shock domain factors, FRG Y2-like
C Runt
C MYRF
B Other transcription factors
C HMGI(Y)
C NUPR
C Pocket domain Rb
C Pocket domain CBP
C T-box
C DMRT
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
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AProkaryotic type
B Helix-turn-helix
C AraC family
D XNC1_0814 Regulator of the 4HPA-hydroxylase operon K02508 hpaA; AraC family transcriptional regulator, 4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein
D XNC1_2695 Regulatory protein soxS K13631 soxS; AraC family transcriptional regulator, mar-sox-rob regulon activator
D XNC1_0688 rob; transcriptional activator for resistance to antibiotics, organic solvents and heavy metals (AraC/XylS family) (right origin-binding protein) K05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator
D XNC1_1176 Exoenzyme S synthesis regulatory protein exsA K20968 exsA; AraC family transcriptional regulator, exoenzyme S synthesis regulatory protein ExsA
D XNC1_2595 ada; bifunctional: transcriptional regulator of DNA repair (AraC/Xyl family) (N-terminal); O6-methylguanine-DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
C LysR family
D XNC1_0699 putative transcriptional regulator K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D XNC1_4028 gcvA; transcriptional regulator (postitive) of cleavage of glycine (LysR family) K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D XNC1_0375 ilvY; transcriptional activator for isoleucine and valine synthesis (LysR family) K02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC
D XNC1_3893 metR; transcriptional regulator of methionine biosynthesis (LysR family) K03576 metR; LysR family transcriptional regulator, regulator for metE and metH
D XNC1_3784 nhaR; transcriptional activator of cation transport (LysR family) K03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA
D XNC1_0272 oxyR; transcriptional regulator of oxidative stress, regulates intracellular hydrogen peroxide (LysR family) K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator
D XNC1_1097 argP; inhibitor of replication initiation; transcriptional regulator of dnaA and argK (LysR family) K05596 argP; LysR family transcriptional regulator, arginine and lysine transport system/DNA replication regulator
D XNC1_1043 leuO; putative transcriptional regulator of leucine biosynthesis with periplasmic binding protein domain (LysR family) K05798 leuO; LysR family transcriptional regulator, transcriptional activator for leuABCD operon
D XNC1_4203 cynR; cyn operon positive regulator (LysR family) K11921 cynR; LysR family transcriptional regulator, cyn operon transcriptional activator
D XNC1_2417 cysB; transcriptional regulator of biosynthesis of L-cysteine and regulator of sulfur assimilation (LysR familiy) K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator
D XNC1_0561 yeaT; putative transcriptional regulator with periplasmic binding protein domain (LysR family) K16135 dmlR; LysR family transcriptional regulator, transcriptional activator for dmlA
D XNC1_2866 yjiE; putative transcriptional regulator with periplasmic binding protein domain (LysR family) K21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT
D XNC1_4229 putative LysR-family transcriptional regulator K21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT
D XNC1_0364 HTH-type transcriptional regulator hdfR (H-NS-depdendent flhDC regulator) K23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator
C DeoR family
D XNC1_4471 glpR; transcriptional repressor for the dissimilation of sn-glycerol 3-phosphate (DeoR family) K02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor
C LacI family
D XNC1_0043 rbsR; transcriptional repressor for ribose metabolism (GalR/LacI family) K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D XNC1_0428 putative transcriptional repressor for ribose metabolism (GalR/LacI family) K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D XNC1_0222 cytR; transcriptional repressor for genes of nucleoside catabolism and recycling (GalR/LacI family) K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG
D XNC1_1047 fruR; transcriptional regulator of the control of carbon and energy metabolism (GalR/LacI family) K03435 fruR1; LacI family transcriptional regulator, fructose operon transcriptional repressor
D XNC1_1876 purR; transcriptional repressor for de novo purine nucleotide synthesis (GalR/LacI family) K03604 purR; LacI family transcriptional regulator, purine nucleotide synthesis repressor
C GntR family
D XNC1_3188 Histidine utilization repressor K05836 hutC; GntR family transcriptional regulator, histidine utilization repressor
D XNC1_2546 fadR; transcriptional regulator (positive regulator of fabB and fabA, negative regulator of fad), with acyl-CoA (GntR family) K03603 fadR; GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA
D XNC1_1079 pdhR; transcriptional repressor for pyruvate dehydrogenase complex (GntR family) K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
C TetR/AcrR family
D XNC1_1246 betI; transcriptional repressor for the cellular response to osmotic stress (TetR/AcrR family) K02167 betI; TetR/AcrR family transcriptional regulator, transcriptional repressor of bet genes
D XNC1_0959 acrR; transcriptional repressor for multidrug efflux pump (TetR/AcrR family) K03577 acrR; TetR/AcrR family transcriptional regulator, acrAB operon repressor
D XNC1_0179 ttk; putative transcriptional regulator of dUTPase subunit with homeodomain-like DNA binding domain (TetR/AcrR family) K05501 slmA; TetR/AcrR family transcriptional regulator
D XNC1_1459 ybiH; putative transcriptional repressor with homeodomain-like DNA binding domain (TetR/AcrR family) K23777 cecR; TetR/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity
C Lrp/AsnC family
D XNC1_0036 asnC; transcriptional regulator of asparagine biosynthesis (AsnC family) K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D XNC1_1548 lrp; Leucine-responsive regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D XNC1_0972 ybaO; putative transcriptional regulator (AsnC familiy) K05800 decR; Lrp/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator
C LuxR family
D XNC1_4283 malT; transcriptional activator of maltose utilization, binds maltotriose (inducer) and ATP (LysR familiy) K03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein
C MarR family
D XNC1_1883 slyA; transcriptional activator for hemolysin (MarR family) K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
D XNC1_1312 mprA; transcriptional repressor of multidrug resistance pump (MarR family) K15974 emrR; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB
C MerR family
D XNC1_0933 cueR; transcriptional repressor for CopA a copper exporting ATPase (MerR family) K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D XNC1_0345 zntR; Zn(II)-responsive transcriptional regulator, regulates Zn export (MerR family) K13638 zntR; MerR family transcriptional regulator, Zn(II)-responsive regulator of zntA
C Fur family
D XNC1_1360 fur; transcriptional repressor of iron transport (Fur family) K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D XNC1_3934 zur; transcriptional repressor of Zn transport system (Fur family) K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
C IclR family
D XNC1_3945 iclR; transcriptional repressor for glyoxylate bypass (IclR family) K13641 iclR; IclR family transcriptional regulator, acetate operon repressor
C CRP/FNR family
D XNC1_4337 crp; transcriptional regulator, cyclic AMP receptor protein (CAMP-binding family), interacts with RNAP K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D XNC1_2240 fnr; Fumarate and nitrate reduction regulatory protein K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
C Rrf2 family
D XNC1_3297 iscR; repressor of the iscRSUA operon, involved in assembly of Fe-S clusters K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
D XNC1_0462 conserved hypothetical protein K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor
C ArsR family
C XRE family
C PadR family
C Other families
D XNC1_2173 yebK; putative transcriptional regulator with phosphosugar-binding domain K19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator
D XNC1_0288 birA; bifunctional: biotin-[acetylCoA carboxylase] holoenzyme synthetase; transcriptional repressor of biotin synthesis (BirA family) K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D XNC1_0800 fis; DNA-binding protein for site-specific recombination and inversion, transcription of rRNA and tRNA operons, and DNA replication K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D XNC1_0685 trpR; transcriptional repressor for tryptophan biosynthesis (TrpR family) K03720 trpR; TrpR family transcriptional regulator, trp operon repressor
D XNC1_1231 prpR; transcriptional activator of propionate catabolism (EBP family) K02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein
D XNC1_0486 sfsB; transcriptional activator of maltose metabolism K07724 ner; Ner family transcriptional regulator
D XNC1_0827 sfsB; transcriptional activator of maltose metabolism K07724 ner; Ner family transcriptional regulator
D XNC1_1969 conserved hypothetical protein K07724 ner; Ner family transcriptional regulator
D XNC1_2606 putative Sugar fermentation stimulation protein B (Ner-like protein) K07724 ner; Ner family transcriptional regulator
D XNC1_3355 Putatiave helix-turn-helix regulatory protein K07724 ner; Ner family transcriptional regulator
D XNC1_3406 sfsB; Sugar fermentation stimulation protein B (Ner-like protein) K07724 ner; Ner family transcriptional regulator
D XNC1_3424 putative sugar fermentation stimulation protein K07724 ner; Ner family transcriptional regulator
D XNC1_3507 sfsB; Sugar fermentation stimulation protein B (Ner-like protein) K07724 ner; Ner family transcriptional regulator
D XNC1_3522 sfsB; sugar fermentation stimulation protein (Ner-like protein) (fragment) K07724 ner; Ner family transcriptional regulator
D XNC1_3544 sfsB; sugar fermentation stimulation protein B (Ner-like protein) K07724 ner; Ner family transcriptional regulator
D XNC1_3615 DNA-binding protein Ner K07724 ner; Ner family transcriptional regulator
D XNC1_3662 Sugar fermentation stimulation protein B (Ner-like protein) (fragment) K07724 ner; Ner family transcriptional regulator
D XNC1_3971 conserved hypothetical protein K07724 ner; Ner family transcriptional regulator
D XNC1_4098 sfsB; Sugar fermentation stimulation protein B (Ner-like protein) K07724 ner; Ner family transcriptional regulator
D XNC1_0681 nadR; transcriptional regulator of NAD biosynthesis; regulator of PnuC activity; NMN adenylyltransferase K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]
D XNC1_4232 hipB; hipB protein K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB
D XNC1_1349 putative Helix-turn-helix domain protein K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D XNC1_4612 ygjM; putative transcriptional regulator with DNA-binding domain K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D XNC1_2123 putative Transcriptional regulator, Fis family K12146 hyfR; hydrogenase-4 transcriptional activator
D XNC1_1429 modE; transcriptional repressor for molybdate uptake K02019 modE; molybdate transport system regulatory protein
D XNC1_0104 putative transcriptional regulator with DNA-binding domain K07726 K07726; putative transcriptional regulator
D XNC1_3616 BamHI control element (fragment) K07729 K07729; putative transcriptional regulator
B Ribbon-helix-helix
C CopG family
C Other families
D XNC1_0225 metJ; transcriptional repressor for methionine biosynthesis (MetJ family) K03764 metJ; MetJ family transcriptional regulator, methionine regulon repressor
D XNC1_1673 putA; multifunctional: transcriptional repressor of proline utilization; proline dehydrogenase; pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D XNC1_1941 relB; Qin prophage; part of two-component toxin-antitoxin system with RelE, transcriptional repressor of relBE operon K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
B Other transcription factors
C BglG family
C Others
D XNC1_0986 bolA; transcriptional activator of morphogenic pathway (BolA family), important in general stress response K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D XNC1_p0002 hypothetical protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D XNC1_3879 rfaH; transcriptional activator affecting biosynthesis, assembly and export of lipopolysaccharide core, F pilin, and haemolysin K05785 rfaH; transcriptional antiterminator RfaH
D XNC1_0484 argR; transcriptional repressor of arginine synthesis (ArgR familiy) K03402 argR; transcriptional regulator of arginine metabolism
D XNC1_1354 nagC; transcriptional repressor of genes for catabolic enzymes (NagC/XylR (ROK) family) K02565 nagC; N-acetylglucosamine repressor
D XNC1_2617 tyrR; transcriptional regulator of aromatic amino acid biosynthesis and aromatic amino acid transport (EBP family) K03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport
D XNC1_2664 gcvR; transcriptional repressor for cleavage of glycine K03567 gcvR; glycine cleavage system transcriptional repressor
D XNC1_4631 paaX; transcriptional repressor for phenylacetic acid degradation K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
D XNC1_2623 pspF; transcriptional activator of phage shock proteins (EBP family) K03974 pspF; psp operon transcriptional activator
D XNC1_2620 pspC; transcriptional activator of the psp operon with PspB, phage shock protein K03973 pspC; phage shock protein C
D XNC1_4209 rnk; regulator of nucleoside diphosphate kinase K06140 rnk; regulator of nucleoside diphosphate kinase
D XNC1_2586 putative phage-related protein K07733 alpA; prophage regulatory protein
D XNC1_3345 alpA; Prophage CP4-57 regulatory protein K07733 alpA; prophage regulatory protein
D XNC1_3442 putative phage-related protein K07733 alpA; prophage regulatory protein
D XNC1_3955 Prophage CP4-57 regulatory K07733 alpA; prophage regulatory protein
D XNC1_4250 putative phage-related protein K07733 alpA; prophage regulatory protein
D XNC1_3104 conserved hypothetical protein K07735 algH; putative transcriptional regulator
D XNC1_0895 dksA; DnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D XNC1_0763 putative transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains K07738 nrdR; transcriptional repressor NrdR
D XNC1_1254 crl; transcriptional regulator of cryptic genes for curli formation and fibronectin binding K11926 crl; sigma factor-binding protein Crl
D XNC1_1048 Protein mraZ K03925 mraZ; transcriptional regulator MraZ
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 21, 2025
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Classification taken and modified from TRANSFAC 7.0