+F Repair protein KO
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DNA Repair and Recombination Proteins - Yersinia pestis Z176003
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D YPZ3_1572 ogt; putative methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D YPZ3_2376 phrB; putative deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E YPZ3_2385 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E YPZ3_0775 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E YPZ3_1618 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D YPZ3_0543 mutator protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D YPZ3_0044 dut; deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D YPZ3_1572 ogt; putative methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D YPZ3_0065 bifunctional regulatory protein/DNA repair protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D YPZ3_2376 phrB; putative deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E YPZ3_2385 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E YPZ3_1891 putative glycosidase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E YPZ3_0775 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E YPZ3_3494 tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E YPZ3_0047 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E YPZ3_1618 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E YPZ3_1677 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E YPZ3_1194 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E YPZ3_3294 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E YPZ3_0833 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E YPZ3_0038 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E YPZ3_2633 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E YPZ3_0016 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E YPZ3_0279 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E YPZ3_1048 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E YPZ3_1866 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E YPZ3_3396 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E YPZ3_0016 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E YPZ3_0038 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E YPZ3_2633 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F YPZ3_3306 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F YPZ3_3305 rpoC; DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F YPZ3_0199 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F YPZ3_2067 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E YPZ3_2953 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E YPZ3_0370 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E YPZ3_0915 mutH; DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E YPZ3_1422 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E YPZ3_2455 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E YPZ3_0966 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E YPZ3_pMT0052 DNA polymerase III K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E YPZ3_3515 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E YPZ3_3037 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E YPZ3_2302 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E YPZ3_2083 holB; DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E YPZ3_0988 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E YPZ3_2751 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E YPZ3_0416 holD; DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
D DNA ligase
E YPZ3_0038 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E YPZ3_2633 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E YPZ3_3396 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E YPZ3_0301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E YPZ3_0280 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E YPZ3_0133 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E YPZ3_1740 putative methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E YPZ3_0928 exodeoxyribonuclease V beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E YPZ3_0926 recC; exodeoxyribonuclease V gamma chain K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E YPZ3_0929 exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E YPZ3_2910 recA; recombinase A K03553 recA; recombination protein RecA
E YPZ3_1767 ruvA; Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
E YPZ3_1766 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E YPZ3_1768 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E YPZ3_0095 priA; primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E YPZ3_2753 priC; primosomal replication protein n K04067 priC; primosomal replication protein N''
E YPZ3_1422 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E YPZ3_2823 periplasmic binding transport protein K03546 sbcC; DNA repair protein SbcC/Rad50
E YPZ3_2822 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E YPZ3_2910 recA; recombinase A K03553 recA; recombination protein RecA
E YPZ3_0430 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E YPZ3_3514 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
E YPZ3_0034 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E YPZ3_0833 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E YPZ3_2401 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E YPZ3_2749 recombination protein RecR K06187 recR; recombination protein RecR
E YPZ3_1003 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E YPZ3_2825 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E YPZ3_1767 ruvA; Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
E YPZ3_1766 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E YPZ3_1768 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E YPZ3_2117 hypothetical protein K15342 cas1; CRISP-associated protein Cas1
E YPZ3_1159 putative DEAD box helicase family protein K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E YPZ3_2823 periplasmic binding transport protein K03546 sbcC; DNA repair protein SbcC/Rad50
E YPZ3_2822 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E YPZ3_0147 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F YPZ3_1120 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F YPZ3_3513 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F YPZ3_1635 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F YPZ3_0833 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F YPZ3_2401 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F YPZ3_2749 recombination protein RecR K06187 recR; recombination protein RecR
F YPZ3_0038 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F YPZ3_2633 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F YPZ3_1422 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F YPZ3_3388 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F YPZ3_0279 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F YPZ3_1048 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F YPZ3_1670 hns; DNA-binding protein Hns K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D YPZ3_2838 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D YPZ3_2910 recA; recombinase A K03553 recA; recombination protein RecA
D YPZ3_0271 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D YPZ3_1003 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D YPZ3_0503 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D YPZ3_0301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D YPZ3_0280 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D YPZ3_2909 recX; RecA regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D YPZ3_3425 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D YPZ3_1314 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D YPZ3_1111 dinG; putative ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D YPZ3_1753 putative DEAD box family helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D YPZ3_0543 mutator protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D YPZ3_0044 dut; deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D YPZ3_2338 nrdE; ribonucleotide-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D YPZ3_1118 nrdA; ribonucleotide-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D YPZ3_2337 nrdF; ribonucleotide-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D YPZ3_1117 nrdB; ribonucleotide-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024