+D	AMR gene	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Antimicrobial Resistance Genes - Kitasatospora sp. MMS16-BH015</h2>
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A<b>Gene variants</b>
B  beta-Lactamase genes
C    Class A [MT]
C    Class D [MT]
C    Class C [MT]
C    Class B [MT]
B  Aminoglycoside resistance genes
C    N-Acetyltransferases
D      CFP65_4429 Putative aminoglycoside 3-N-acetyltransferase	K00662 aacC; aminoglycoside 3-N-acetyltransferase [EC:2.3.1.81] 
C    Other acetyltransferases
C    O-Nucleotidyltransferases
C    O-Phosphotransferases
D      CFP65_1351 hydroxyurea phosphotransferase	K04343 strB; streptomycin 6-kinase [EC:2.7.1.72] 
D      CFP65_2465 kinase	K04343 strB; streptomycin 6-kinase [EC:2.7.1.72] 
C    16S rRNA methyltransferases
B  Tetracycline resistance genes
C    Transporters
D      CFP65_2071 oleandomycin transport system permease protein	K18233 oleC5; oleandomycin transport system permease protein 
C    Others
B  Macrolide resistance genes
C    23S rRNA methyltransferases
C    Transporters
D      CFP65_2070 oleandomycin transport system ATP-binding protein	K18232 oleC4; oleandomycin transport system ATP-binding protein 
C    Others
D      CFP65_0708 erythromycin esterase	K06880 ereA_B; erythromycin esterase [EC:3.1.1.-] 
B  Phenicol resistance genes
C    Transporters
C    Acetyltransferases
C    Phosphotransferase
D      CFP65_1149 chloramphenicol phosphotransferase	K18554 cpt; chloramphenicol 3-O phosphotransferase [EC:2.7.1.-] 
D      CFP65_0115 chloramphenicol 3-O phosphotransferase	K18554 cpt; chloramphenicol 3-O phosphotransferase [EC:2.7.1.-] 
D      CFP65_0935 chloramphenicol phosphotransferase	K18554 cpt; chloramphenicol 3-O phosphotransferase [EC:2.7.1.-] 
C    23S rRNA methyltransferase
B  Sulfonamide resistance genes
C    Dihydropteroate synthase
B  Trimethoprim resistance genes
C    Dihydrofolate reductases
B  Quinolone resistance genes
C    Transporter
D      CFP65_0251 MFS transporter	K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein 
D      CFP65_3362 MFS transporter	K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein 
C    Other
B  Rifamycin resistance genes
C    ADP-ribosyl transferases
C    Oxygenases
D      CFP65_0086 FAD-dependent oxidoreductase	K21267 iri; rifampicin monooxygenase [EC:1.14.13.211] 
B  Fosfomycin resistance genes
C    Transferases
C    Others
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A<b>Gene sets</b>
B  beta-Lactam resistance modules
C    Methicillin resistance [MD:M00625]
C    beta-Lactam resistance, Bla system [MD:M00627]
D      CFP65_6008 hypothetical protein	K02172 blaR1; bla regulator protein blaR1 
D      CFP65_6684 Class A beta-lactamase	K17836 penP; beta-lactamase class A [EC:3.5.2.6] 
D      CFP65_6391 hypothetical protein	K17836 penP; beta-lactamase class A [EC:3.5.2.6] 
C    Imipenem resistance, repression of porin OprD [MD:M00745]
B  Vancomycin resistance modules
C    Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
D      CFP65_0729 hypothetical protein	K18353 vanJ; vancomycin resistance protein VanJ 
D      CFP65_2065 membrane protein	K18353 vanJ; vancomycin resistance protein VanJ 
C    Vancomycin resistance, D-Ala-D-Ser type [MD:M00652]
D      B  Tetracycline resistance
C    Tetracycline resistance, efflux pump Tet38 [MD:M00704]
B  CAMP resistance modules
C    Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [MD:M00725]
D      CFP65_0779 hypothetical protein	K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] 
D      CFP65_5861 thioester reductase	K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] 
C    Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [MD:M00726]
D      CFP65_2668 hypothetical protein	K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] 
C    Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [MD:M00730]
C    Cationic antimicrobial peptide (CAMP) resistance, protease PgtE [MD:M00744]
B  Multipdrug resistance modules
C    Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
C    Multidrug resistance, efflux pump MexCD-OprJ [MD:M00639]
D      CFP65_0250 TetR family transcriptional regulator	K18294 nfxB; TetR/AcrR family transcriptional regulator, mexCD-oprJ operon repressor 
C    Multidrug resistance, efflux pump MexEF-OprN [MD:M00641]
C    Multidrug resistance, efflux pump MexJK-OprM [MD:M00642]
C    Multidrug resistance, efflux pump MexXY-OprM [MD:M00643]
C    Multidrug resistance, efflux pump MexPQ-OpmE [MD:M00769]
C    Multidrug resistance, efflux pump AdeABC [PATH:map01501] [MD:M00649]
C    Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
C    Multidrug resistance, efflux pump MdtEF-TolC [MD:M00697]
C    Multidrug resistance, efflux pump BpeEF-OprC [MD:M00698]
C    Multidrug resistance, efflux pump AbcA [MD:M00700]
C    Multidrug resistance, efflux pump NorB [MD:M00702]
C    Multidrug resistance, efflux pump QacA [MD:M00714]
D      CFP65_0251 MFS transporter	K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein 
D      CFP65_3362 MFS transporter	K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein 
C    Multidrug resistance, efflux pump MepA [MD:M00705]
C    Multidrug resistance, repression of porin OmpF [MD:M00746]
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#Last updated: December 28, 2017