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Transcription Machinery
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AEukaryotic type
B RNA polymerase II system
C RNA polymerase II
D Core subunits
E K03006 RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
E K03010 RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
E K03011 RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
E K03008 RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
D Pol II specific subunits
E K03012 RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
E K03015 RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
E K03017 RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
E K21987 POLR2M, GRINL1A; DNA-directed RNA polymerase II subunit GRINL1A
D Pol I, II, III common subunits
E K03013 RPABC1, RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E K03014 RPABC2, RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E K03016 RPABC3, RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E K03009 RPABC4, RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E K03007 RPABC5, RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
D Pol IV and V specific subunits
E K16250 NRPD1; DNA-directed RNA polymerase IV subunit 1 [EC:2.7.7.6]
E K16251 NRPE1; DNA-directed RNA polymerase V subunit 1 [EC:2.7.7.6]
E K16252 NRPD2, NRPE2; DNA-directed RNA polymerase IV and V subunit 2 [EC:2.7.7.6]
E K16253 NRPD7, NRPE7; DNA-directed RNA polymerase IV and V subunit 7
C Basal transcription factors
D TFIIA
E K03122 TFIIA1, GTF2A1, TOA1; transcription initiation factor TFIIA large subunit
E K03123 TFIIA2, GTF2A2, TOA2; transcription initiation factor TFIIA small subunit
D TFIIB
E K03124 TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
D TFIID
E K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
E K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
E K23358 TAF1; transcription initiation factor TFIID subunit 1, fungi type [EC:2.3.1.48]
E K03128 TAF2; transcription initiation factor TFIID subunit 2
E K14650 TAF3; transcription initiation factor TFIID subunit 3
E K03129 TAF4; transcription initiation factor TFIID subunit 4
E K03130 TAF5; transcription initiation factor TFIID subunit 5
E K03131 TAF6; transcription initiation factor TFIID subunit 6
E K03132 TAF7; transcription initiation factor TFIID subunit 7
E K14649 TAF8; transcription initiation factor TFIID subunit 8
E K14535 TAF9; transcription initiation factor TFIID subunit 9
E K03133 TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
E K03134 TAF10; transcription initiation factor TFIID subunit 10
E K03135 TAF11; transcription initiation factor TFIID subunit 11
E K03126 TAF12; transcription initiation factor TFIID subunit 12
E K03127 TAF13; transcription initiation factor TFIID subunit 13
E K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
E K14651 TAF15, NPL3; transcription initiation factor TFIID subunit 15
D TFIIE
E K03136 TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
E K03137 TFIIE2, GTF2E2, TFA2; transcription initiation factor TFIIE subunit beta
D TFIIF
E K03138 TFIIF1, GTF2F1, TFG1; transcription initiation factor TFIIF subunit alpha
E K03139 TFIIF2, GTF2F2, TFG2; transcription initiation factor TFIIF subunit beta [EC:5.6.2.-]
D TFIIH
E K03141 TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
E K03142 TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
E K03143 TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
E K03144 TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
E K10843 ERCC3, XPB; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E K10844 ERCC2, XPD; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E K10845 TTDA, GTF2H5, TFB5; TFIIH basal transcription factor complex TTD-A subunit
E K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E K10842 MNAT1; CDK-activating kinase assembly factor MAT1
E K06634 CCNH; cyclin H
C Mediator complex
D Head
E K15128 MED6; mediator of RNA polymerase II transcription subunit 6
E K15129 MED8; mediator of RNA polymerase II transcription subunit 8
E K15130 MED8; mediator of RNA polymerase II transcription subunit 8, fungi type
E K15131 MED11; mediator of RNA polymerase II transcription subunit 11
E K15132 MED11; mediator of RNA polymerase II transcription subunit 11, fungi type
E K15133 MED17; mediator of RNA polymerase II transcription subunit 17
E K15134 SRB4, MED17; mediator of RNA polymerase II transcription subunit 17, fungi type
E K15135 MED18; mediator of RNA polymerase II transcription subunit 18
E K15136 SRB5, MED18; mediator of RNA polymerase II transcription subunit 18, fungi type
E K15137 MED19; mediator of RNA polymerase II transcription subunit 19
E K15138 ROX3, MED19; mediator of RNA polymerase II transcription subunit 19, fungi type
E K13528 MED20; mediator of RNA polymerase II transcription subunit 20
E K15139 MED22; mediator of RNA polymerase II transcription subunit 22
E K15140 SRB6, MED22; mediator of RNA polymerase II transcription subunit 22, fungi type
E K15141 MED28; mediator of RNA polymerase II transcription subunit 28
E K15142 MED29; mediator of RNA polymerase II transcription subunit 29
E K15143 MED30; mediator of RNA polymerase II transcription subunit 30
D Middle
E K15144 MED1; mediator of RNA polymerase II transcription subunit 1
E K15145 MED1; mediator of RNA polymerase II transcription subunit 1, fungi type
E K15146 MED4; mediator of RNA polymerase II transcription subunit 4
E K15147 MED5, NUT1; mediator of RNA polymerase II transcription subunit 5
E K15148 MED7; mediator of RNA polymerase II transcription subunit 7
E K15149 MED9; mediator of RNA polymerase II transcription subunit 9
E K15150 CSE2, MED9; mediator of RNA polymerase II transcription subunit 9, fungi type
E K15151 MED10, NUT2; mediator of RNA polymerase II transcription subunit 10
E K15152 MED21, SRB7; mediator of RNA polymerase II transcription subunit 21
E K15153 MED31, SOH1; mediator of RNA polymerase II transcription subunit 31
D Tail
E K15154 MED2; mediator of RNA polymerase II transcription subunit 2
E K15155 MED3, HRS1, PGD1; mediator of RNA polymerase II transcription subunit 3
E K15156 MED14, RGR1; mediator of RNA polymerase II transcription subunit 14
E K15157 MED15; mediator of RNA polymerase II transcription subunit 15
E K15158 GAL11, MED15; mediator of RNA polymerase II transcription subunit 15, fungi type
E K15159 MED16; mediator of RNA polymerase II transcription subunit 16
E K15160 SIN4, MED16; mediator of RNA polymerase II transcription subunit 16, fungi type
D CDK-module
E K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
E K15161 CCNC, SSN8; cyclin-C
E K15162 MED12; mediator of RNA polymerase II transcription subunit 12
E K15163 SRB8, MED12; mediator of RNA polymerase II transcription subunit 12, fungi type
E K15164 MED13; mediator of RNA polymerase II transcription subunit 13
E K15165 SSN2, MED13; mediator of RNA polymerase II transcription subunit 13, fungi type
D Other mediators
E K15166 MED23; mediator of RNA polymerase II transcription subunit 23
E K15167 MED24; mediator of RNA polymerase II transcription subunit 24
E K15168 MED25; mediator of RNA polymerase II transcription subunit 25
E K15169 MED26; mediator of RNA polymerase II transcription subunit 26
E K15170 MED27; mediator of RNA polymerase II transcription subunit 27
E K27471 MED32; mediator of RNA polymerase II transcription subunit 32
E K27472 MED33; mediator of RNA polymerase II transcription subunit 33
C Coactivators
D SAGA/TFTC/STAGA complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11313 SUPT3H, SPT3; transcription initiation protein SPT3
E K11359 SPT7; transcriptional activator SPT7
E K11360 SPT8; transcriptional activator SPT8
E K11361 SPT20, ADA5; transcription factor SPT20
E K11362 HFI1, ADA1; transcriptional coactivator HFI1/ADA1
E K11314 TADA2A, ADA2; transcriptional adapter 2-alpha
E K15127 TADA2B; transcriptional adapter 2-beta
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K11317 TADA1, STAF42; transcriptional adapter 1
E K03128 TAF2; transcription initiation factor TFIID subunit 2
E K03129 TAF4; transcription initiation factor TFIID subunit 4
E K03130 TAF5; transcription initiation factor TFIID subunit 5
E K03131 TAF6; transcription initiation factor TFIID subunit 6
E K03132 TAF7; transcription initiation factor TFIID subunit 7
E K14535 TAF9; transcription initiation factor TFIID subunit 9
E K03133 TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
E K03134 TAF10; transcription initiation factor TFIID subunit 10
E K03126 TAF12; transcription initiation factor TFIID subunit 12
E K11363 SGF11; SAGA-associated factor 11
E K11364 SGF29; SAGA-associated factor 29
E K11365 SGF73; SAGA-associated factor 73
E K11316 SUPT7L; STAGA complex 65 subunit gamma
E K11318 ATXN7, SCA7; ataxin-7
E K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E K11368 ENY2, DC6, SUS1; enhancer of yellow 2 transcription factor
E K11366 USP22_27_51, UBP8; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E K12830 SF3B3, SAP130, RSE1; splicing factor 3B subunit 3
D BAF/PBAF complex
E K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
E K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
E K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
E K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
E K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
E K05692 ACTB_G1; actin beta/gamma 1
E K11340 ACTL6A, INO80K; actin-like protein 6A
E K11652 ACTL6B; actin-like protein 6B
E K11653 ARID1; AT-rich interactive domain-containing protein 1
E K11765 ARID2; AT-rich interactive domain-containing protein 2
E K11757 PBRM1, PB1; protein polybromo-1
D SWI/SNF complex
E K11771 SWI1, ADR6; SWI/SNF chromatin-remodeling complex subunit SWI1
E K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
E K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
E K11772 SWI3; SWI/SNF complex subunit SWI3
E K11773 SNF6; SWI/SNF complex component SNF6
E K11774 SNF11; SWI/SNF complex component SNF11
E K11775 SNF12, SWP73; SWI/SNF complex component SWP73
E K11776 SWP82; SWI/SNF complex component SWP82
E K11767 ARP7, SWP61; actin-related protein 7
E K11768 ARP9, SWP59; actin-related protein 9
E K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
D RSC complex
E K11756 RSC1_2; chromatin structure-remodeling complex subunit RSC1/2
E K11758 RSC3_30; chromatin structure-remodeling complex subunit RSC3/30
E K11759 RSC4; chromatin structure-remodeling complex subunit RSC4
E K11760 RSC6; chromatin structure-remodeling complex subunit RSC6
E K11761 NPL6, RSC7; chromatin structure-remodeling complex protein RSC7
E K11762 RSC8, SWH3, SSR2; chromatin structure-remodeling complex subunit RSC8
E K11763 RSC9; chromatin structure-remodeling complex subunit RSC9
E K11764 LDB7, RSC14; chromatin structure-remodeling complex protein RSC14
E K11766 RSC58; chromatin structure-remodeling complex subunit RSC58
E K11767 ARP7, SWP61; actin-related protein 7
E K11768 ARP9, SWP59; actin-related protein 9
E K11769 HTL1; chromatin structure-remodeling complex protein HTL1
E K11770 SFH1; chromatin structure-remodeling complex subunit SFH1
E K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
D Others
E K25815 SUB1; activated RNA polymerase II transcriptional coactivator p15
E K25827 CCAR1; cell division cycle and apoptosis regulator protein 1
E K25828 CALCOCO1; calcium-binding and coiled-coil domain-containing protein 1
C Other transcription-related factors
D Transcription elongation factors
E K03145 TFIIS; transcription elongation factor S-II
E K15171 SUPT4H1, SPT4; transcription elongation factor SPT4
E K15172 SUPT5H, SPT5; transcription elongation factor SPT5
E K11292 SUPT6H, SPT6; transcription elongation factor SPT6
D Transcription termination factor
E K15173 TTF2; transcription termination factor 2 [EC:5.6.2.-]
E K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
E K14401 CPSF1, CFT1; cleavage and polyadenylation specificity factor subunit 1
E K14403 CPSF3, YSH1; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E K14404 CPSF4, YTH1; cleavage and polyadenylation specificity factor subunit 4
E K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E K06100 SYMPK; symplekin
E K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E K12619 XRN2, RAT1; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E K14845 RAI1, DOM3Z; RAT1-interacting protein
E K15559 RTT103; regulator of Ty1 transposition protein 103
E K13219 SFPQ, PSF; splicing factor, proline- and glutamine-rich
E K15560 NRD1; protein NRD1
E K13191 RBM16, SCAF8; RNA-binding protein 16
E K13167 SCAF4, SFRS15; SR-related and CTD-associated factor 4
E K15561 NAB3; nuclear polyadenylated RNA-binding protein 3
E K10706 SETX, ALS4, SEN1; ATP-dependent RNA/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3]
E K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D PAF1 complex
E K15174 PAF1; RNA polymerase II-associated factor 1
E K15175 CDC73; parafibromin
E K15176 CTR9; RNA polymerase-associated protein CTR9
E K15177 LEO1; RNA polymerase-associated protein LEO1
E K15178 RTF1; RNA polymerase-associated protein RTF1
D NELF complex
E K15179 WHSC2, NELFA; negative elongation factor A
E K15180 COBRA1, NELFB; negative elongation factor B
E K15181 TH1L, NELFD; negative elongation factor C/D
E K15182 RDBP, NELFE; negative elongation factor E
D Super elongation complex (SEC)
E K15183 ELL; RNA polymerase II elongation factor ELL
E K15184 AFF1; AF4/FMR2 family member 1
E K15185 AFF4; AF4/FMR2 family member 4
E K15186 EAF; ELL-associated factor
E K15187 MLLT1_3, ENL, AF9; YEATS domain-containing protein 1/3
E K15188 CCNT; cyclin T
E K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
D Little elongation complex (LEC)
E K15183 ELL; RNA polymerase II elongation factor ELL
E K26143 ICE1; little elongation complex subunit 1
E K26144 ICE2; little elongation complex subunit 2
E K24388 ZC3H8; zinc finger CCCH domain-containing protein 8
D Brd4/P-TEFb complex
E K11722 BRD4; bromodomain-containing protein 4
E K15188 CCNT; cyclin T
E K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
D BUR kinase complex
E K15562 BUR1, SGV1; serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]
E K15563 BUR2; protein BUR2
D CTDK-I complex
E K00916 CTK1; CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23]
E K15564 CTK2; CTD kinase subunit beta
E K15565 CTK3; CTD kinase subunit gamma
D 7SK RNP complex
E K15189 HEXIM1_2; protein HEXIM1/2
E K15190 MEPCE, BCDIN3; 7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-]
E K15191 LARP7; La-related protein 7
E K15188 CCNT; cyclin T
E K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
D DBIRD complex
E K25816 CCAR2, DBC1; cell cycle and apoptosis regulator protein 2
E K13204 ZNF326; zinc finger protein 326
D Others
E K03121 TFII-I, GTF2I; transcription initiation factor TFII-I
E K27274 GTF2IRD1; general transcription factor II-I repeat domain-containing protein 1
E K15192 BTAF1, MOT1; TATA-binding protein-associated factor [EC:5.6.2.-]
E K21751 DR1, NC2-beta; down-regulator of transcription 1
E K21752 DRAP1, NC2-alpha; Dr1-associated corepressor
E K15193 SPTY2D1, SPT2; protein SPT2
E K15194 AFF2; AF4/FMR2 family member 2
E K15195 AFF3; AF4/FMR2 family member 3
E K15732 CTDP1, FCP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]
E K18998 CPL1_2; RNA polymerase II C-terminal domain phosphatase-like 1/2 [EC:3.1.3.16]
E K18999 CPL3_4; RNA polymerase II C-terminal domain phosphatase-like 3/4 [EC:3.1.3.16]
E K15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]
E K17498 SPN1, IWS1; transcription factor SPN1
E K17494 CSRNP; cysteine/serine-rich nuclear protein
E K20826 RPAP1; RNA polymerase II-associated protein 1
E K20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]
E K23002 RPAP3; RNA polymerase II-associated protein 3
E K06666 TUP1; general transcriptional corepressor TUP1
E K06665 SSN6, CYC8; general transcriptional corepressor CYC8
E K12412 MCM1; pheromone receptor transcription factor
E K21388 AHR1; adhesion and hyphal regulator 1
E K23326 CCNK; cyclin K
E K24104 GPN; GPN-loop GTPase
E K26769 TCEAL1; transcription elongation factor A protein-like 1
B RNA polymerase III system
C RNA polymerase III
D Core subunits
E K03018 RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
E K03021 RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
E K03027 RPAC1, RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
E K03020 RPAC2, RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
D Pol III specific subunits
E K03023 RPC3, POLR3C; DNA-directed RNA polymerase III subunit RPC3
E K03026 RPC4, POLR3D; DNA-directed RNA polymerase III subunit RPC4
E K14721 RPC5, POLR3E; DNA-directed RNA polymerase III subunit RPC5
E K03025 RPC6, POLR3F; DNA-directed RNA polymerase III subunit RPC6
E K03024 RPC7, POLR3G; DNA-directed RNA polymerase III subunit RPC7
E K03022 RPC8, POLR3H; DNA-directed RNA polymerase III subunit RPC8
E K25304 RPC9, CRCP; DNA-directed RNA polymerase III subunit RPC9
E K03019 RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC11
D Pol I, II, III common subunits
E K03013 RPABC1, RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E K03014 RPABC2, RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E K03016 RPABC3, RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E K03009 RPABC4, RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E K03007 RPABC5, RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
C Basal transcription factors
D TFIIIA
E K09191 GTF3A; general transcription factor IIIA
D TFIIIB
E K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
E K15196 BRF1, GTF3B; transcription factor IIIB 90 kDa subunit
E K15197 BRF2; transcription factor IIIB 50 kDa subunit
E K15198 BDP1, TFC5; transcription factor TFIIIB component B''
D TFIIIC
E K15199 GTF3C1; general transcription factor 3C polypeptide 1
E K15200 GTF3C2; general transcription factor 3C polypeptide 2
E K15201 GTP3C3, TFC4; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)
E K11310 GTF3C4, KAT12; general transcription factor 3C polypeptide 4 [EC:2.3.1.48]
E K15202 GTF3C5, TFC1; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)
E K15203 GTF3C6; general transcription factor 3C polypeptide 6
D TFIIIC, fungi type
E K15202 GTF3C5, TFC1; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)
E K15204 TFC3; transcription factor C subunit 3
E K15201 GTP3C3, TFC4; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)
E K15205 TFC6; transcription factor C subunit 6
E K15206 TFC7; transcription factor C subunit 7
E K15207 TFC8; transcription factor C subunit 8
C Other transcription-related factors
D snRNA-activating protein complex (SNAPc)
E K15208 SNAPC1; snRNA-activating protein complex subunit 1
E K15209 SNAPC2; snRNA-activating protein complex subunit 2
E K15210 SNAPC3; snRNA-activating protein complex subunit 3
E K09453 SNAPC4; snRNA-activating protein complex subunit 4
E K15211 SNAPC5; snRNA-activating protein complex subunit 5
D Octamer transcription factors
E K09364 POU2F, OTF; POU domain transcription factor, class 2
E K09367 POU5F; POU domain transcription factor, class 5
D Others
E K20828 ZNF143_76, STAF; zinc finger protein 143/76
E K25817 MAF1; repressor of RNA polymerase III transcription MAF1
B RNA polymerase I system
C RNA polymerase I
D Core subunits
E K02999 RPA1, POLR1A; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
E K03002 RPA2, POLR1B; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
E K03027 RPAC1, RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
E K03020 RPAC2, RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
D Pol I specific subunits
E K03005 RPA49, POLR1E; DNA-directed RNA polymerase I subunit RPA49
E K03004 RPA43, POLR1F, TWISTNB; DNA-directed RNA polymerase I subunit RPA43
E K25436 POLR1G; DNA-directed RNA polymerase I subunit RPA34
E K03003 RPA34; DNA-directed RNA polymerase I subunit RPA34
E K03000 RPA12, POLR1H, ZNRD1; DNA-directed RNA polymerase I subunit RPA12
E K03001 RPA14; DNA-directed RNA polymerase I subunit RPA14
D Pol I, II, III common subunits
E K03013 RPABC1, RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E K03014 RPABC2, RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E K03016 RPABC3, RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E K03009 RPABC4, RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E K03007 RPABC5, RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
C Basal transcription factors
D SL1/TIF-1B
E K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
E K15212 TAF1A, SL1; TATA box-binding protein-associated factor RNA polymerase I subunit A
E K15213 TAF1B; TATA box-binding protein-associated factor RNA polymerase I subunit B
E K15214 TAF1C; TATA box-binding protein-associated factor RNA polymerase I subunit C
E K15215 TAF1D; TATA box-binding protein-associated factor RNA polymerase I subunit D
C Other transcription-related factors
D UBF
E K09273 UBTF; upstream-binding transcription factor
D Transcription initiation factors
E K15216 RRN3, TIFIA; RNA polymerase I-specific transcription initiation factor RRN3
E K15217 RRN5; RNA polymerase I-specific transcription initiation factor RRN5
E K15218 RRN6; RNA polymerase I-specific transcription initiation factor RRN6
E K15219 RRN7; RNA polymerase I-specific transcription initiation factor RRN7
E K15220 RRN9; RNA polymerase I-specific transcription initiation factor RRN9
E K15221 RRN10; RNA polymerase I-specific transcription initiation factor RRN10
E K15222 RRN11; RNA polymerase I-specific transcription initiation factor RRN11
E K15223 UAF30, SPP27; upstream activation factor subunit UAF30
D Transcription elongation factors
E K15171 SUPT4H1, SPT4; transcription elongation factor SPT4
E K15172 SUPT5H, SPT5; transcription elongation factor SPT5
D NoRC (nucleolar remodeling complex)
E K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
E K15224 BAZ2A, TIP5; bromodomain adjacent to zinc finger domain protein 2A
D CTDK-I complex
E K00916 CTK1; CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23]
E K15564 CTK2; CTD kinase subunit beta
E K15565 CTK3; CTD kinase subunit gamma
D Transcription termination factors
E K15225 TTF1; transcription termination factor 1
E K19387 PTRF; polymerase I and transcript release factor
D Others
E K25818 NOLC1; nucleolar and coiled-body phosphoprotein 1
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AProkaryotic type
B Bacterial type
C RNA polymerase
D Core subunits
E K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
E K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
E K13797 rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
E K03048 rpoE; DNA-directed RNA polymerase subunit delta
E K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D Sigma factors
E K03086 rpoD; RNA polymerase primary sigma factor
E K03087 rpoS; RNA polymerase nonessential primary-like sigma factor
E K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily
E K23514 fecI, prhI; RNA polymerase sigma-19 factor, ECF subfamily
E K24073 cnrH; RNA polymerase sigma factor CnrH
E K03089 rpoH; RNA polymerase sigma-32 factor
E K03090 sigB; RNA polymerase sigma-B factor
E K03091 sigE_F_G; RNA polymerase sigma-E/F/G factor
E K27000 sigH; RNA polymerase sigma-H factor
E K03093 sigI; RNA polymerase sigma-I factor
E K26992 sigO; RNA polymerase sigma-O factor
E K03092 rpoN; RNA polymerase sigma-54 factor
E K02405 fliA, whiG; RNA polymerase sigma factor FliA
E K24072 xpf; positive control factor
C Other transcription-related factors
D RNA polymerase-associated proteins
E K03580 hepA; ATP-dependent helicase HepA [EC:5.6.2.-]
E K02600 nusA; transcription termination/antitermination protein NusA
E K03625 nusB; transcription antitermination protein NusB
E K02601 nusG; transcription termination/antitermination protein NusG
E K03599 sspA, mglA; stringent starvation protein A
E K03600 sspB; stringent starvation protein B
E K17752 rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
E K17762 rsbS; rsbT antagonist protein RsbS
E K17763 rsbR; rsbT co-antagonist protein RsbR
E K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3]
E K19707 rsbQ; sigma-B regulation protein RsbQ
E K05518 rsbX; phosphoserine phosphatase RsbX [EC:3.1.3.3]
E K04749 rsbV; anti-sigma B factor antagonist
E K04757 rsbW; serine/threonine-protein kinase RsbW [EC:2.7.11.1]
E K03597 rseA; sigma-E factor negative regulatory protein RseA
E K03598 rseB; sigma-E factor negative regulatory protein RseB
E K03803 rseC; sigma-E factor negative regulatory protein RseC
D Transcription elongation factors
E K06204 dksA; RNA polymerase-binding transcription factor
E K03624 greA; transcription elongation factor GreA
E K04760 greB; transcription elongation factor GreB
D Transcription termination factor
E K03628 rho; transcription termination factor Rho
E K19000 rof; Rho-binding antiterminator
B Archaeal type
C RNA polymerase
D Core subunits
E K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
E K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
E K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
E K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
E K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
E K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
E K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
E K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
E K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
E K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
E K03054 rpoI; DNA-directed RNA polymerase subunit I [EC:2.7.7.6]
E K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
E K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
E K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
E K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
E K00960 rpo13; DNA-directed RNA polymerase subunit 13 [EC:2.7.7.6]
C Basal transcription factors
D TFB
E K03124 TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
D TFE
E K03136 TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
D TFS
E K03057 tfs; transcription factor S
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 9, 2024