+F Chromosome and associated proteins
#
Chromosome and Associated Proteins
!
AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
D K06636 SMC1; structural maintenance of chromosome 1
D K06669 SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
D K06670 SCC1, MCD1, RAD21; cohesin complex subunit SCC1
D K06671 STAG1_2, SCC3, IRR1; cohesin complex subunit SA-1/2
C Adherin complex
D K06672 SCC2, NIPBL; cohesin loading factor subunit SCC2
D K06673 SCC4; cohesin loading factor subunit SCC4
D K11266 MAU2; MAternally affected uncoordination
D K11267 PDS5; sister chromatid cohesion protein PDS5
D K11268 ESCO, ECO1; N-acetyltransferase [EC:2.3.1.-]
C CTF18-RFC complex
D K11269 CTF18, CHL12; chromosome transmission fidelity protein 18
D K11270 CTF8; chromosome transmission fidelity protein 8
D K11271 DSCC1, DCC1; sister chromatid cohesion protein DCC1
D K10755 RFC2_4; replication factor C subunit 2/4
D K10756 RFC3_5; replication factor C subunit 3/5
C Fork protection complex
D K10997 TIMELESS, TOF1, SWI1; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D K10998 TIPIN, CSM3, SWI3; replication fork protection complex subunit TIPIN/Csm3/Swi3
D K25773 CLSPN; claspin
D K11272 MRC1; mediator of replication checkpoint protein 1
C Other sister chromatid cohesion factors
D K11273 DDX11, CHL1, CTF1; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
D K11274 WDHD1, CTF4; chromosome transmission fidelity protein 4
D K17390 CDCA5; sororin
D K20791 NAA10_11, ARD1_2; N-alpha-acetyltransferase 10/11 [EC:2.3.1.255]
D K20792 NAA15_16; N-alpha-acetyltransferase 15/16, NatA auxiliary subunit
D K20793 NAA50, NAT5; N-alpha-acetyltransferase 50 [EC:2.3.1.258 2.3.1.309]
B Meiosis-specific proteins
C Cohesin complex and associated proteins
D K06636 SMC1; structural maintenance of chromosome 1
D K06669 SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
D K13054 REC8L; meiotic recombination protein REC8, animal type
D K12780 REC8; meiotic recombination protein REC8, fungi type
D K13055 STAG3; cohesin complex subunit SA-3
D K25163 WAPL; wings apart-like protein
C Synaptonemal complex
D K19533 SYCP1; synaptonemal complex protein 1
D K19529 SYCP2; synaptonemal complex protein 2
D K19528 SYCP3; synaptonemal complex protein 3
D K19534 SYCE1; synaptonemal complex central element protein 1
D K19535 SYCE2; synaptonemal complex central element protein 2
D K19536 SYCE3; synaptonemal complex central element protein 3
D K24574 TEX11; testis-expressed protein 11
D K19537 TEX12; testis-expressed sequence 12 protein
D K25705 SIX6OS1; protein SIX6OS1
C DSB formation-related proteins
D K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
D K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
D K13209 EWSR1; RNA-binding protein EWS
D K10878 SPO11; meiotic recombination protein SPO11
D K24789 TOP6BL; type 2 DNA topoisomerase 6 subunit B-like
D K26086 MEI4; meiosis-specific protein MEI4
D K26084 REC114; meiotic recombination protein REC114
D K26087 ANKRD31; ankyrin repeat domain-containing protein 31
D K25318 MEI1; meiosis inhibitor protein 1
D K12778 HORMAD, HOP1; meiosis-specific protein
D K26085 IHO1, CCDC36; interactor of HORMAD1 protein 1
D K26453 MPS1; protein multipolar spindle 1
C Others
D K22420 MEIOB; meiosis-specific with OB domain-containing protein [EC:3.1.-.-]
D K22421 SPATA22; spermatogenesis-associated protein 22
D K10872 DMC1; meiotic recombination protein DMC1
D K15271 HFM1, MER3; ATP-dependent DNA helicase HFM1/MER3 [EC:5.6.2.4]
D K08740 MSH4; DNA mismatch repair protein MSH4
D K08741 MSH5; DNA mismatch repair protein MSH5
D K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
B Nucleosome assembly factors
C Histones
D K11275 H1_5; histone H1/5
D K11251 H2A; histone H2A
D K11252 H2B; histone H2B
D K11253 H3; histone H3
D K11254 H4; histone H4
C Histone chaperones
D Nucleoplasmins
E K11276 NPM1; nucleophosmin 1
E K11277 NPM2; nucleophosmin 2
E K11278 NPM3; nucleophosmin 3
D NAPs (Nucleosome assembly proteins)
E K11279 NAP1L1, NRP; nucleosome assembly protein 1-like 1
E K11280 NAP1L2, BPX; nucleosome assembly protein 1-like 2
E K11281 NAP1L3, BNAP; nucleosome assembly protein 1-like 3
E K11282 NAP1L4, NAP2; nucleosome assembly protein 1-like 4
E K11283 NAP1L5; nucleosome assembly protein 1-like 5
E K11284 TSPYL1; TSPY-like 1
E K11285 TSPYL2, CINAP, DENTT; TSPY-like 2
E K11286 TSPYL3; TSPY-like 3
E K11287 TSPYL4; TSPY-like 4
E K11288 TSPYL5; TSPY-like 5
E K11289 TSPYL6; TSPY-like 6
E K11290 SET, TAF1, I2PP2A; template-activating factor I
D CAF-1
E K10750 CHAF1A; chromatin assembly factor 1 subunit A
E K10751 CHAF1B; chromatin assembly factor 1 subunit B
E K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
D FACT complex
E K09272 SSRP1, POB3; FACT complex subunit SSRP1/POB3
E K25639 SUPT16H, SPT16; FACT complex subunit SPT16
E K27246 NHP6; non-histone chromosomal protein 6
D Other Histone chaperones and regulators
E K10753 ASF1; histone chaperone ASF1
E K19531 CDAN1; codanin-1
E K24865 CDIN1; CDAN1-interacting nuclease 1
E K11291 NASP; nuclear autoantigenic sperm protein
E K11292 SUPT6H, SPT6; transcription elongation factor SPT6
E K11293 HIRA, HIR1; protein HIRA/HIR1
E K09033 JDP2; jun dimerization protein 2
E K11294 NCL, NSR1; nucleolin
E K18648 ANP32E; acidic leucine-rich nuclear phosphoprotein 32 family member E
E K26243 HP1BP3; heterochromatin protein 1-binding protein 3
C HMG (high mobility group) proteins
D K09282 HMGA1; high mobility group AT-hook protein 1
D K09283 HMGA2; high mobility group AT-hook protein 2
D K10802 HMGB1; high mobility group protein B1
D K11295 HMGB2; high mobility group protein B2
D K11296 HMGB3; high mobility group protein B3
D K11297 HMGB4; high mobility group protein B4
D K25507 HMGBP; high mobility group B protein, plant
D K11299 HMGN1; high-mobility group nucleosome-binding domain-containing protein 1
D K11300 HMGN2; high-mobility group nucleosome-binding domain-containing protein 2
D K11301 HMGN3, TRIP7; high-mobility group nucleosome-binding domain-containing protein 3
D K11302 HMGN4; high-mobility group nucleosome-binding domain-containing protein 4
D K17045 HMGN5; high-mobility group nucleosome-binding domain-containing protein 5
D K11298 HMGXB4, HMG2L1; HMG domain-containing protein 4
B Histone modification proteins
C HATs (histone acetyltransferases)
D K11303 HAT1, KAT1; histone acetyltransferase 1 [EC:2.3.1.48]
D K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
D K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
D K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
D K23358 TAF1; transcription initiation factor TFIID subunit 1, fungi type [EC:2.3.1.48]
D K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
D K11308 MYST1, MOF, KAT8; histone acetyltransferase MYST1 [EC:2.3.1.48]
D K11307 MYST2, HBO1, KAT7; histone acetyltransferase MYST2 [EC:2.3.1.48]
D K11305 MYST3, KAT6A; histone acetyltransferase MYST3 [EC:2.3.1.48]
D K11306 MYST4, KAT6B; histone acetyltransferase MYST4 [EC:2.3.1.48]
D K11309 RTT109, KAT11; regulator of Ty1 transposition protein 109
D K11310 GTF3C4, KAT12; general transcription factor 3C polypeptide 4 [EC:2.3.1.48]
D K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
D K11255 NCOA2, TIF2, KAT13C; nuclear receptor coactivator 2
D K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
D K02223 CLOCK, KAT13D; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
D K00653 CDY; chromodomain protein Y [EC:2.3.1.48]
D K22767 MCC1; histone acetyltransferase MCC1 [EC:2.3.1.48]
D K22768 MBD9; methyl-CpG-binding domain-containing protein 9 [EC:2.3.1.48]
D K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D K20794 NAA40, NAT4; N-alpha-acetyltransferase 40 [EC:2.3.1.257]
D K21121 NAA60; N-alpha-acetyltransferase 60 [EC:2.3.1.259]
C HAT complexes
D PCAF complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11313 SUPT3H, SPT3; transcription initiation protein SPT3
E K11314 TADA2A, ADA2; transcriptional adapter 2-alpha
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K03130 TAF5; transcription initiation factor TFIID subunit 5
E K03131 TAF6; transcription initiation factor TFIID subunit 6
E K03133 TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
E K03134 TAF10; transcription initiation factor TFIID subunit 10
E K03126 TAF12; transcription initiation factor TFIID subunit 12
D STAGA complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11313 SUPT3H, SPT3; transcription initiation protein SPT3
E K11316 SUPT7L; STAGA complex 65 subunit gamma
E K11317 TADA1, STAF42; transcriptional adapter 1
E K15127 TADA2B; transcriptional adapter 2-beta
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K03130 TAF5; transcription initiation factor TFIID subunit 5
E K03131 TAF6; transcription initiation factor TFIID subunit 6
E K03133 TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
E K03134 TAF10; transcription initiation factor TFIID subunit 10
E K03126 TAF12; transcription initiation factor TFIID subunit 12
E K12830 SF3B3, SAP130, RSE1; splicing factor 3B subunit 3
D TFTC complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11313 SUPT3H, SPT3; transcription initiation protein SPT3
E K15127 TADA2B; transcriptional adapter 2-beta
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K11318 ATXN7, SCA7; ataxin-7
E K03128 TAF2; transcription initiation factor TFIID subunit 2
E K03129 TAF4; transcription initiation factor TFIID subunit 4
E K03130 TAF5; transcription initiation factor TFIID subunit 5
E K03131 TAF6; transcription initiation factor TFIID subunit 6
E K03132 TAF7; transcription initiation factor TFIID subunit 7
E K03133 TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
E K03134 TAF10; transcription initiation factor TFIID subunit 10
E K03126 TAF12; transcription initiation factor TFIID subunit 12
E K12830 SF3B3, SAP130, RSE1; splicing factor 3B subunit 3
D TIP60 complex
E K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11319 ING3; inhibitor of growth protein 3
E K11320 EP400; E1A-binding protein p400 [EC:5.6.2.-]
E K11321 BRD8; bromodomain-containing protein 8
E K11322 EPC; enhancer of polycomb-like protein
E K11324 DMAP1, SWC4, EAF2; DNA methyltransferase 1-associated protein 1
E K04499 RUVBL1, RVB1, INO80H; RuvB-like protein 1 [EC:5.6.2.4]
E K11338 RUVBL2, RVB2, INO80J; RuvB-like protein 2 [EC:5.6.2.3]
E K11339 MORF4L1, MRG15, EAF3; mortality factor 4-like protein 1
E K11340 ACTL6A, INO80K; actin-like protein 6A
E K05692 ACTB_G1; actin beta/gamma 1
E K11341 YEATS4, GAS41, YAF9; YEATS domain-containing protein 4
E K11342 MORF4L2, MRGX; mortality factor 4-like protein 2
E K11343 MRGBP; MRG-binding protein
E K11344 MEAF6, EAF6; chromatin modification-related protein EAF6
D HBO1 complex
E K11307 MYST2, HBO1, KAT7; histone acetyltransferase MYST2 [EC:2.3.1.48]
E K11346 ING4; inhibitor of growth protein 4
E K11345 ING5; inhibitor of growth protein 5
E K11347 JADE1, PHF17; protein Jade-1
E K22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]
E K22156 JADE3; protein Jade-3
E K11344 MEAF6, EAF6; chromatin modification-related protein EAF6
D MOZ/MORF complex
E K11305 MYST3, KAT6A; histone acetyltransferase MYST3 [EC:2.3.1.48]
E K11306 MYST4, KAT6B; histone acetyltransferase MYST4 [EC:2.3.1.48]
E K11345 ING5; inhibitor of growth protein 5
E K11348 BRPF1; bromodomain and PHD finger-containing protein 1
E K11349 BRD1, BRPF2; bromodomain-containing protein 1
E K11350 BRPF3; bromodomain and PHD finger-containing protein 3
E K11344 MEAF6, EAF6; chromatin modification-related protein EAF6
D SAGA complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11313 SUPT3H, SPT3; transcription initiation protein SPT3
E K11359 SPT7; transcriptional activator SPT7
E K11360 SPT8; transcriptional activator SPT8
E K11361 SPT20, ADA5; transcription factor SPT20
E K21245 SUPT20H; transcription factor SPT20 homolog
E K11362 HFI1, ADA1; transcriptional coactivator HFI1/ADA1
E K11314 TADA2A, ADA2; transcriptional adapter 2-alpha
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K11363 SGF11; SAGA-associated factor 11
E K11364 SGF29; SAGA-associated factor 29
E K11365 SGF73; SAGA-associated factor 73
E K03130 TAF5; transcription initiation factor TFIID subunit 5
E K03131 TAF6; transcription initiation factor TFIID subunit 6
E K03133 TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
E K03134 TAF10; transcription initiation factor TFIID subunit 10
E K03126 TAF12; transcription initiation factor TFIID subunit 12
E K11366 USP22_27_51, UBP8; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E K11368 ENY2, DC6, SUS1; enhancer of yellow 2 transcription factor
D SLIK complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11313 SUPT3H, SPT3; transcription initiation protein SPT3
E K11359 SPT7; transcriptional activator SPT7
E K11361 SPT20, ADA5; transcription factor SPT20
E K11362 HFI1, ADA1; transcriptional coactivator HFI1/ADA1
E K11314 TADA2A, ADA2; transcriptional adapter 2-alpha
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K11363 SGF11; SAGA-associated factor 11
E K11364 SGF29; SAGA-associated factor 29
E K11365 SGF73; SAGA-associated factor 73
E K03130 TAF5; transcription initiation factor TFIID subunit 5
E K03131 TAF6; transcription initiation factor TFIID subunit 6
E K03133 TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
E K03134 TAF10; transcription initiation factor TFIID subunit 10
E K03126 TAF12; transcription initiation factor TFIID subunit 12
E K11366 USP22_27_51, UBP8; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E K11369 RTG2; retrograde regulation protein 2
D ADA-HAT complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K11314 TADA2A, ADA2; transcriptional adapter 2-alpha
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K11364 SGF29; SAGA-associated factor 29
E K11370 AHC1; ADA HAT complex component 1
E K11371 AHC2; ADA HAT complex component 2
D HAT-A2 complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K11314 TADA2A, ADA2; transcriptional adapter 2-alpha
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
D ATAC complex
E K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
E K11314 TADA2A, ADA2; transcriptional adapter 2-alpha
E K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
E K11364 SGF29; SAGA-associated factor 29
E K24536 ZZZ3; ZZ-type zinc finger-containing protein 3
E K24537 KAT14; cysteine-rich protein 2-binding protein
E K21751 DR1, NC2-beta; down-regulator of transcription 1
E K24538 MBIP; MAP3K12-binding inhibitory protein 1
E K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
E K24539 YEATS2; YEATS domain-contaning protein 2
D HATB complex
E K11303 HAT1, KAT1; histone acetyltransferase 1 [EC:2.3.1.48]
E K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
E K11372 HIF1; HAT1-interacting factor 1
D NSL complex
E K11308 MYST1, MOF, KAT8; histone acetyltransferase MYST1 [EC:2.3.1.48]
E K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
E K18400 KANSL1; KAT8 regulatory NSL complex subunit 1
E K18401 KANSL2; KAT8 regulatory NSL complex subunit 2
E K16719 KANSL3, RCD1; regulatory NSL complex subunit 3
E K18402 PHF20; PHD finger protein 20
E K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E K11674 MCRS1, INO80Q; microspherule protein 1
E K14966 HCFC1; host cell factor 1
D MSL complex
E K11308 MYST1, MOF, KAT8; histone acetyltransferase MYST1 [EC:2.3.1.48]
E K13163 MSL1; male-specific lethal 1
E K13164 MSL2; male-specific lethal 2
E K18403 MSL3; male-specific lethal 3
D NuA3 complex
E K11378 SAS3; histone acetyltransferase SAS3 [EC:2.3.1.48]
E K11379 YNG1; protein YNG1
E K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
E K11380 NTO1; NuA3 HAT complex component NTO1
D NuA4 complex
E K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
E K08874 TRRAP; transformation/transcription domain-associated protein
E K11396 YNG2, EAF4; chromatin modification-related protein YNG2
E K11341 YEATS4, GAS41, YAF9; YEATS domain-containing protein 4
E K11397 EAF1, VID21; chromatin modification-related protein VID21
E K11324 DMAP1, SWC4, EAF2; DNA methyltransferase 1-associated protein 1
E K11339 MORF4L1, MRG15, EAF3; mortality factor 4-like protein 1
E K11398 EAF5; chromatin modification-related protein EAF5
E K11344 MEAF6, EAF6; chromatin modification-related protein EAF6
E K11399 EAF7; chromatin modification-related protein EAF7
E K11322 EPC; enhancer of polycomb-like protein
E K26270 MBTD1; MBT domain-containing protein 1
E K05692 ACTB_G1; actin beta/gamma 1
E K11400 ARP4; actin-related protein 4
D SAS complex
E K11401 SAS2; histone acetyltransferase SAS2 [EC:2.3.1.48]
E K11402 SAS4; something about silencing protein 4
E K11403 SAS5; something about silencing protein 5
C HDACs (histone deacetylases)
D Class I HDACs
E K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
E K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
E K11482 HOS1; histone deacetylase HOS1 [EC:3.5.1.98]
E K11483 HOS2; histone deacetylase HOS2 [EC:3.5.1.98]
E K11484 HOS3; histone deacetylase HOS3 [EC:3.5.1.98]
D Class II HDACs
E K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
E K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
E K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
E K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
D SIRTs (sirtuins, class III HDACs)
E K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
E K11412 SIRT2, SIR2L2; NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
E K11413 SIRT3, SIR2L3; NAD-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
E K11414 SIRT4, SIR2L4; NAD-dependent protein deacetylase/lipoamidase sirtuin 4 [EC:2.3.1.286 2.3.1.313]
E K11415 SIRT5, SIR2L5; NAD-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
E K11416 SIRT6, SIR2L6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
E K11417 SIRT7, SIR2L7; NAD-dependent protein deacetylase sirtuin 7 [EC:2.3.1.286]
D Class IV HDACs
E K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
C HDAC complexes
D Sin3A-HDAC complex
E K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E K11644 SIN3A; paired amphipathic helix protein Sin3a
E K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
E K11659 RBBP7; histone-binding protein RBBP7
E K19201 SUDS3, SAP45; Sin3 histone deacetylase corepressor complex component SDS3
E K19202 SAP30; histone deacetylase complex subunit SAP30
E K14324 SAP18; histone deacetylase complex subunit SAP18
E K19192 SAP130; histone deacetylase complex subunit SAP130
E K19193 SAP25; histone deacetylase complex subunit SAP25
E K19194 ARID4A, RBP1; AT-rich interactive domain-containing protein 4A
E K19195 ARID4B; AT-rich interactive domain-containing protein 4B
E K19196 BRMS1; breast cancer metastasis-suppressor 1 and related proteins
E K19197 ING1; inhibitor of growth protein 1
E K19198 ING2; inhibitor of growth protein 2
E K26090 SINHCAF; SIN3-HDAC complex-associated factor
D BRAF-HDAC complex
E K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E K24650 HMG20B; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
E K11450 KDM1A, AOF2, LSD1; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
E K11829 RCOR1, COREST; REST corepressor 1
E K24651 PHF21A; PHD finger protein 21A
E K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4
E K27275 ZNF217; zinc finger protein 217
E K27276 GSE1; genetic suppressor element 1
E K03121 TFII-I, GTF2I; transcription initiation factor TFII-I
D REST complex
E K09222 REST; RE1-silencing transcription factor
E K11644 SIN3A; paired amphipathic helix protein Sin3a
E K23213 SIN3B; paired amphipathic helix protein Sin3b
E K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E K11829 RCOR1, COREST; REST corepressor 1
E K26242 RCOR2_3; REST corepressor 2/3
E K11450 KDM1A, AOF2, LSD1; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
E K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
E K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
D SHIP complex
E K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
E K26598 HSPA2; heat shock 70kDa protein 2
E K26581 KCTD19; BTB/POZ domain-containing protein KCTD19
D MiDAC complex
E K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E K26582 MIDEAS, ELMSAN1; mitotic deacetylase-associated SANT domain protein
E K08707 DNTTIP1; deoxynucleotidyltransferase terminal-interacting protein 1
E K26583 TRERF1; transcriptional-regulating factor 1
E K26584 ZNF541; zinc finger protein 541
D SMART complex
E K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
E K04650 NCOR1, N-CoR; nuclear receptor co-repressor 1
E K06065 NCOR2, SMRT; nuclear receptor co-repressor 2
E K15307 GPS2; G protein pathway suppressor 2
E K04508 TBL1; transducin (beta)-like 1
D Other HDAC associated proteins
E K21486 ANKRA2; ankyrin repeat family A protein 2
E K21436 ANKRD11_12; ankyrin repeat domain-containing protein 11/12
E K21869 DDX53, CAGE; ATP-dependent RNA helicase DDX53 [EC:5.6.2.7]
E K23192 MYT1; myelin transcription factor 1
E K23193 MYT1L; myelin transcription factor 1-like protein
E K23398 TRIP4; activating signal cointegrator 1
E K24081 ZMYND15; zinc finger MYND domain-containing protein 15
E K24660 HMG20A; high mobility group protein 20A
E K24907 DIP2A; disco-interacting protein 2 homolog A [EC:6.2.1.1]
E K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E K26244 PHF12, RCO1; transcriptional regulatory protein PHF12/RCO1
E K26245 PHO23; transcriptional regulatory protein PHO23
E K26246 UME1; transcriptional regulatory protein UME1
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
E K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
E K11427 DOT1L, DOT1; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
E K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
E K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
E K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
E K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
E K09187 MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
E K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
E K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
E K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
E K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
E K11424 WHSC1, MMSET, NSD2; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
E K11425 WHSC1L1, NSD3; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
E K11432 PRDM2, RIZ; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
E K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
E K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
E K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
E K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
E K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
E K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
E K11422 SETD1, SET1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
E K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
E K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
E K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
E K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
E K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
E K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
E K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
E K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
E K23700 SET2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
E K24407 SET9; [histone H4]-lysine20 N-trimethyltransferase [EC:2.1.1.372]
E K11419 SUV39H, CLR4; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
E K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
E K24405 SUVH1; [histone H3]-lysine9 N-dimethyltransferase [EC:2.1.1.368]
E K22748 ATXR3, SDG2; [histone H3]-lysine4 N-trimethyltransferase ATXR3 [EC:2.1.1.354]
E K24406 ATXR5_6; [histone H3]-lysine27 N-methyltransferase [EC:2.1.1.369]
D PRMTs (protein arginine metyltransferases)
E K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
E K11435 PRMT2; type I protein arginine methyltransferase [EC:2.1.1.319]
E K11436 PRMT3; type I protein arginine methyltransferase [EC:2.1.1.319]
E K05931 CARM1, PRMT4; type I protein arginine methyltransferase [EC:2.1.1.319]
E K11437 PRMT6; type I protein arginine methyltransferase [EC:2.1.1.319]
E K11439 PRMT8; type I protein arginine methyltransferase [EC:2.1.1.319]
E K02516 PRMT5, HSL7; type II protein arginine methyltransferase [EC:2.1.1.320]
E K19737 PRMT9; type II protein arginine methyltransferase [EC:2.1.1.320]
E K11438 PRMT7; type III protein arginine methyltransferase [EC:2.1.1.321]
E K18477 RMT2; type IV protein arginine methyltransferase [EC:2.1.1.322]
C HMT complexes
D COMPASS/SET1 complex
E K11422 SETD1, SET1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E K14960 CXXC1, SPP1, CPS40; COMPASS component SPP1
E K14961 RBBP5, SWD1, CPS50; COMPASS component SWD1
E K14962 WDR82, SWD2, CPS35; COMPASS component SWD2
E K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
E K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E K14965 DPY30; protein dpy-30
E K14966 HCFC1; host cell factor 1
D COMPASS/SET1 complex (yeast)
E K11422 SETD1, SET1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E K14960 CXXC1, SPP1, CPS40; COMPASS component SPP1
E K14961 RBBP5, SWD1, CPS50; COMPASS component SWD1
E K14962 WDR82, SWD2, CPS35; COMPASS component SWD2
E K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
E K14967 BRE2, CPS60; COMPASS component BRE2
E K14968 CPS25, SDC1; COMPASS component SDC1
E K14969 SHG1, CPS15; COMPASS component SHG1
D MLL-HCF complex
E K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
E K09187 MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
E K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E K14965 DPY30; protein dpy-30
E K14961 RBBP5, SWD1, CPS50; COMPASS component SWD1
E K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
E K14966 HCFC1; host cell factor 1
E K27390 HCFC2; host cell factor 2
E K14970 MEN1, MNN1; menin
D MLL3/MLL4 complex
E K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
E K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
E K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E K14965 DPY30; protein dpy-30
E K14961 RBBP5, SWD1, CPS50; COMPASS component SWD1
E K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
E K14971 NCOA6, ASC2; nuclear receptor coactivator 6
E K14972 PAXIP1, PTIP; PAX-interacting protein 1
E K14973 PA1; PAXIP1-associated protein 1
E K11447 UTX, KDM6A; lysine-specific demethylase 6A [EC:1.14.11.68]
D Dot1-containing complex
E K11427 DOT1L, DOT1; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
E K15187 MLLT1_3, ENL, AF9; YEATS domain-containing protein 1/3
E K23588 MLLT6_10, AF17_10; protein AF-17/10
C Histone demethylases
D K11450 KDM1A, AOF2, LSD1; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
D K19413 KDM1B, AOF1, LSD2; lysine-specific histone demethylase 1B [EC:1.-.-.-]
D K10276 FBXL10_11, KDM2; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
D K15601 KDM3; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]
D K06709 KDM4, JMJD2, JHDM3; [histone H3]-trimethyl-L-lysine9/36 demethylase [EC:1.14.11.66 1.14.11.69]
D K11446 KDM5, JARID1; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]
D K11447 UTX, KDM6A; lysine-specific demethylase 6A [EC:1.14.11.68]
D K11448 KDM6B, JMJD3; lysine-specific demethylase 6B [EC:1.14.11.68]
D K23742 UTY, KDM6C; lysine-specific demethylase 6C [EC:1.14.11.68]
D K11445 KDM7A, JHDM1D; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65 1.14.11.-]
D K22610 RSBN1, KDM9; lysine-specific demethylase 9 [EC:1.14.11.-]
D K00478 HR; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]
D K19414 PHF2, JHDM1E; lysine-specific demethylase PHF2 [EC:1.14.11.-]
D K19415 PHF8, JHDM1F; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65 1.14.11.-]
D K16914 RIOX1, NO66; protein-L-histidine (3S)-3-hydroxylase / [histone H3]-trimethyl-L-lysine4/36 demethylase [EC:1.14.11.79 1.14.11.67 1.14.11.69]
D K21760 RIOX2, MINA; protein-L-histidine (3S)-3-hydroxylase / [histone H3]-trimethyl-L-lysine9 demethylase [EC:1.14.11.79 1.14.11.66]
D K19799 RPH1; DNA damage-responsive transcriptional repressor / [histone H3]-trimethyl-L-lysine36 demethylase [EC:1.14.11.69]
D K11449 JMJD1C; jumonji domain-containing protein 1C [EC:1.14.11.-]
D K11323 JMJD6; histone arginine demethylase JMJD6 [EC:1.14.11.-]
D K19219 JMJD7; peptidyl-lysine (3S)-dioxygenase / protease [EC:1.14.11.63 3.4.-.-]
D K11478 JARID2, JMJ; protein Jumonji
D K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
D K24444 JMJ30; [histone H3]-dimethyl/trimethyl-L-lysine36 demethylase [EC:1.14.11.27 1.14.11.-]
C Polycomb repressive complex (PRC) and associated proteins
D Canonical PRC1 (PRC1.2/1.4)
E K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E K11460 PCGF2, RNF110; polycomb group RING finger protein 2
E K11459 PCGF4, BMI1; polycomb group RING finger protein 4
E K11451 CBX2; chromobox protein 2
E K11452 CBX4, PC2; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]
E K11453 CBX6; chromobox protein 6
E K11454 CBX7; chromobox protein 7
E K11455 CBX8, PC3; chromobox protein 8
E K11456 PHC1, EDR1; polyhomeotic-like protein 1
E K11457 PHC2, EDR2; polyhomeotic-like protein 2
E K11458 PHC3, EDR3; polyhomeotic-like protein 3
E PRC1.4 specific proteins
F K11464 SCML1; sex comb on midleg-like protein 1
F K11465 SCML2; sex comb on midleg-like protein 2
F K11461 SCMH1; polycomb protein SCMH1
F K26269 SFMBT; scm-like with four MBT domains protein
D Noncanonical PRC1 (PRC1.1)
E K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E K11487 PCGF1, NSPC1; polycomb group RING finger protein 1
E K11469 RYBP; RING1 and YY1-binding protein
E K11468 YAF2; YY1-associated factor 2
E K10276 FBXL10_11, KDM2; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E K23215 BCOR; bcl-6 corepressor
E K26199 BCORL1; BCL-6 corepressor-like protein 1
E K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
D Noncanonical PRC1 (PRC1.3/1.5)
E K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E K11488 PCGF3; polycomb group RING finger protein 3
E K11489 PCGF5; polycomb group RING finger protein 5
E K11469 RYBP; RING1 and YY1-binding protein
E K11468 YAF2; YY1-associated factor 2
E K03115 CSNK2B; casein kinase II subunit beta
E K23214 AUTS2; autism susceptibility gene 2 protein
E K26253 FBRS; fibrosin-1
E K26254 FBRSL1; fibrosin-1-like protein
E K11805 DCAF7, HAN11; DDB1- and CUL4-associated factor 7
D Noncanonical PRC1 (PRC1.6)
E K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E K11470 PCGF6, MBLR; polycomb group RING finger protein 6
E K11469 RYBP; RING1 and YY1-binding protein
E K11468 YAF2; YY1-associated factor 2
E K09390 E2F6; transcription factor E2F6
E K04683 TFDP1; transcription factor Dp-1
E K04453 MAX; Max protein
E K23399 MGA; MAX gene-associated protein
E K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
E K11586 CBX3, HP1G; chromobox protein 3
E K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
E K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D PRC2.1
E K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
E K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
E K11462 EED; polycomb protein EED
E K11463 SUZ12; polycomb protein SUZ12
E K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
E K11659 RBBP7; histone-binding protein RBBP7
E K11467 PHF1, PCL1; PHD finger protein 1
E K11485 MTF2, PCL2; metal regulatory transcription factor 2
E K11486 PHF19, PCL3; PHD finger protein 19
E K26259 EPOP; elongin BC and Polycomb repressive complex 2-associated protein
E K26260 LCOR; ligand-dependent corepressor
D PRC2.2
E K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
E K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
E K11462 EED; polycomb protein EED
E K11463 SUZ12; polycomb protein SUZ12
E K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
E K11659 RBBP7; histone-binding protein RBBP7
E K17452 AEBP2; zinc finger protein AEBP2
E K11478 JARID2, JMJ; protein Jumonji
D PR-DUB complex
E K08588 BAP1, UCHL2; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
E K11471 ASXL; additional sex combs-like protein
E K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E K14966 HCFC1; host cell factor 1
E K09201 YY; transcription factor YY
E K23219 MBD5; methyl-CpG-binding domain protein 5
E K26585 MBD6; methyl-CpG-binding domain protein 6
E K09404 FOXK; forkhead box protein K
D Other PRC associated proteins
E K11466 SCML4; sex comb on midleg-like protein 4
E K26266 SAMD1; sterile alpha motif domain-containing protein 1
E K27571 SAMD7; sterile alpha motif domain-containing protein 7
E K27582 SAMD11; sterile alpha motif domain-containing protein 11
E K26267 SAP30BP; SAP30-binding protein
E K26258 tay; tay bridge
C Sir proteins
D K11120 SIR1; regulatory protein SIR1
D K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
D K11122 SIR3; regulatory protein SIR3
D K11123 SIR4; regulatory protein SIR4
C Other histone modification proteins
D K00541 NNMT; nicotinamide N-methyltransferase [EC:2.1.1.1]
D K18404 TDRD3; tudor domain-containing protein 3
D K10638 UHRF1, NP95; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D K21870 BANF; barrier-to-autointegration factor
D K22611 SART3, TIP110; squamous cell carcinoma antigen recognized by T-cells 3
D K23216 SETD5; SET domain-containing protein 5
D K23217 SETBP1; SET-binding protein
D K23218 ZMYND11, BS69; zinc finger MYND domain-containing protein 11
D K22832 GAS1; 1,3-beta-glucanosyltransferase GAS1 [EC:2.4.1.-]
D K22833 GAS2; 1,3-beta-glucanosyltransferase GAS2 [EC:2.4.1.-]
D K22834 GAS3; 1,3-beta-glucanosyltransferase GAS3 [EC:2.4.1.-]
D K22835 GAS4; 1,3-beta-glucanosyltransferase GAS4 [EC:2.4.1.-]
D K22836 GAS5; 1,3-beta-glucanosyltransferase GAS5 [EC:2.4.1.-]
D K23399 MGA; MAX gene-associated protein
D K23407 GATAD1; GATA zinc finger domain-containing protein 1
D K24550 BCAS3; breast carcinoma-amplified sequence 3
D K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
D K24690 ZCWPW2; zinc finger CW-type PWWP domain protein 2
D K24752 WDR70; WD repeat-containing protein 70
D K25100 SPEN, SHARP, MINT; Msx2-interacting protein
D K26250 HPF1; histone PARylation factor 1
D K26537 UXT; protein UXT
D K27473 PHF13; PHD finger protein 13
D K27397 PHF14; PHD finger protein 14
B Chromosome condensation proteins
C Condensin I
D K06674 SMC2; structural maintenance of chromosome 2
D K06675 SMC4; structural maintenance of chromosome 4
D K06676 BRRN1, BRN1, CAPH; condensin complex subunit 2
D K06677 YCS4, CNAP1, CAPD2; condensin complex subunit 1
D K06678 YCG1, CAPG; condensin complex subunit 3
C Condensin II
D K06674 SMC2; structural maintenance of chromosome 2
D K06675 SMC4; structural maintenance of chromosome 4
D K11490 NCAPH2; condensin-2 complex subunit H2
D K11491 NCAPD3; condensin-2 complex subunit D3
D K11492 NCAPG2, LUZP5; condensin-2 complex subunit G2
C Other regulators of chromosome condensation
D K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D K11493 RCC1; regulator of chromosome condensation
D K11494 RCBTB; RCC1 and BTB domain-containing protein
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
E K11495 CENPA; histone H3-like centromeric protein A
E K11496 CENPB; centromere protein B
E K11497 CENPC; centromere protein C
E K11498 CENPE, KIF10; centromeric protein E
E K11499 CENPF; centromere protein F
E K11500 CENPH; centromere protein H
E K11501 CENPI; centromere protein I
E K11502 CENPJ; centromere protein J
E K11503 CENPK; centromere protein K
E K11504 CENPL; centromere protein L
E K11505 CENPM; centromere protein M
E K11506 CENPN; centromere protein N
E K11507 CENPO; centromere protein O
E K11508 CENPP; centromere protein P
E K11509 CENPQ; centromere protein Q
E K11510 ITGB3BP, CENPR; centromere protein R
E K11511 APITD1, CENPS, MHF1; centromere protein S
E K11512 CENPT; centromere protein T
E K11513 MLF1IP, CENPU; centromere protein U
E K27583 CENPV; centromere protein V
E K26091 CENPW; centromere protein W
D CPC (chromosomal passenger complex)
E K08731 BIRC5; baculoviral IAP repeat-containing protein 5
E K11514 CDCA8; Borealin
E K11515 INCENP; inner centromere protein
E K11479 AURKB; aurora kinase B [EC:2.7.11.1]
D KMN network proteins
E K11542 CASC5, KNL1; protein CASC5
E MIS12 complex
F K11543 MIS12; kinetochore-associated protein MIS12
F K11544 DSN1; kinetochore-associated protein DSN1
F K11545 NSL1, MIS14, DC8; kinetochore-associated protein NSL1
F K11546 PMF1; polyamine-modulated factor 1
E NDC80 complex
F K11547 NDC80, HEC1, TID3; kinetochore protein NDC80
F K11548 NUF2, CDCA1; kinetochore protein Nuf2
F K11549 SPBC24, SPC24; kinetochore protein Spc24, animal type
F K11550 SPBC25, SPC25; kinetochore protein Spc25, animal type
D Mis6 complex
E K11501 CENPI; centromere protein I
E K11497 CENPC; centromere protein C
E K11551 MIS15, CHL4; central kinetochore subunit Mis15/CHL4
E K11552 MAL2, MCM21; central kinetochore subunit Mal2/MCM21
E K11553 DAD1; DASH complex subunit DAD1
E K11696 CNL2; centromere-localized protein 2
E K11697 FTA7, CNL3; kinetochore protein Fta7
E K11698 SIM4; centromere protein Sim4
D COMA complex
E K11554 CTF19; central kinetochore subunit CTF19
E K11555 OKP1; central kinetochore subunit OKP1
E K11552 MAL2, MCM21; central kinetochore subunit Mal2/MCM21
E K11556 AME1; central kinetochore subunit AME1
D NMS complex
E NDC80 complex
F K11547 NDC80, HEC1, TID3; kinetochore protein NDC80
F K11548 NUF2, CDCA1; kinetochore protein Nuf2
F K11557 SPC24; kinetochore protein Spc24, fungi type
F K11558 SPC25; kinetochore protein Spc25, fungi type
E MIND kinetochore complex
F K11559 mis12, MTW1; kinetochore protein Mis12/MTW1
F K11560 mis13, DSN1; kinetochore protein Mis13/DSN1
F K11561 mis14, NSL1; kinetochor protein Mis14/NSL1
F K11562 NNF1; kinetochore protein NNF1
E K11563 SPC7, SPC105; kinetochore protein Spc7/SPC105
D MIS16-MIS18 complex
E K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
E K11564 MIS18, FASP1; kinetochore protein Mis18
E K11565 OIP5; opa-interacting protein 5
D DASH complex
E K11566 ASK1; DASH complex subunit ASK1
E K11553 DAD1; DASH complex subunit DAD1
E K11567 DAD2, HSK1; DASH complex subunit DAD2
E K11568 DAD3; DASH complex subunit DAD3
E K11569 DAD4, HSK2; DASH complex subunit DAD4
E K02307 DAM1; DASH complex subunit DAM1
E K11570 DUO1; DASH complex subunit DUO1
E K11571 HSK3; DASH complex subunit HSK3
E K11572 SPC19; DASH complex subunit SPC19
E K11573 SPC34; DASH complex subunit SPC34
D CBF3 complex
E K11574 CBF2, CBF3A, CTF14; centromere DNA-binding protein complex CBF3 subunit A
E K11575 CEP3, CBF3B; centromere DNA-binding protein complex CBF3 subunit B
E K11576 CTF13, CBF3C; centromere DNA-binding protein complex CBF3 subunit C
E K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
D Others
E K26092 HJURP; holliday junction recognition protein
E K27273 BOD1; biorientation of chromosomes in cell division protein 1
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
E K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
E K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
E K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
E K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
E K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
E K02180 BUB3; cell cycle arrest protein BUB3
D Motor proteins
E K11498 CENPE, KIF10; centromeric protein E
E RZZ complex
F K11577 KNTC1, ROD; kinetochore-associated protein 1
F K11578 ZW10, DSL1; protein transport protein DSL1/ZW10
F K11579 ZWILCH; protein zwilch
E Dynein complex
F K10413 DYNC1H; dynein cytoplasmic 1 heavy chain
F K10414 DYNC2H, DNCH2; dynein cytoplasmic 2 heavy chain
F K10415 DYNC1I, DNCI; dynein cytoplasmic 1 intermediate chain
F K10416 DYNC1LI, DNCLI; dynein cytoplasmic 1 light intermediate chain
F K10417 DYNC2LI; dynein cytoplasmic 2 light intermediate chain
E K10393 KIF2_24, MCAK; kinesin family member 2/24
D Protein kinases
E K11479 AURKB; aurora kinase B [EC:2.7.11.1]
E K11480 AURKC; aurora kinase C [EC:2.7.11.1]
E K08866 TTK, MPS1; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
E K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
E K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
E K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
D Others
E K20093 ERCC6L, PICH; DNA excision repair protein ERCC-6-like [EC:5.6.2.-]
E K22399 TRIP13; pachytene checkpoint protein 2
E K25866 NUDC; nuclear migration protein NudC
E K26093 MAD2L1BP; MAD2L1-binding protein
E K26094 SKA1; spindle and kinetochore-associated protein 1
E K26095 SKA2; spindle and kinetochore-associated protein 2
E K26096 SKA3; spindle and kinetochore-associated protein 3
E K26097 KNSTRN, SKAP; small kinetochore-associated protein
E K26098 SPDL1; protein Spindly
E K27474 MISP; mitotic interactor and substrate of PLK1
C Other centromeric chromatin formation proteins
D Shugoshin
E K11580 SGOL1; shugoshin-like 1
E K11581 SGOL2; shugoshin-like 2
E K11582 SGO1; shugoshin
D PP2A (protein phosphatase 2A)
E K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
D K11585 CBX1, HP1B, SWI6; chromobox protein 1
D K11586 CBX3, HP1G; chromobox protein 3
D K11587 CBX5, HP1A; chromobox protein 5
C MBPs (metylated DNA binding proteins)
D K11588 MECP2; methyl CpG binding protein 2
D K11589 MBD1; methyl-CpG-binding domain protein 1
D K11590 MBD2; methyl-CpG-binding domain protein 2
D K11591 MBD3; methyl-CpG-binding domain protein 3
D K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
D K23219 MBD5; methyl-CpG-binding domain protein 5
D K10507 ZBTB33, KAISO; zinc finger and BTB domain-containing protein 33
C Other heterochromatin formation proteins
D K10779 ATRX; transcriptional regulator ATRX
D K00558 DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D K17400 DNMT3L; DNA (cytosine-5)-methyltransferase 3-like
D K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D K11644 SIN3A; paired amphipathic helix protein Sin3a
D K11642 CHD3, MI2A; chromodomain-helicase-DNA-binding protein 3 [EC:5.6.2.-]
D K11643 CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
D K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
D K25802 ATF7IP, MCAF; activating transcription factor 7-interacting protein
D K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
D K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
D K11419 SUV39H, CLR4; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
D K19532 LBR; Delta14-sterol reductase (lamin-B receptor) [EC:1.3.1.70]
D K19871 SALL; sal-like protein
D K21871 MPHOSPH8, MPP8; M-phase phosphoprotein 8
D K21872 PPHLN1; periphilin-1
D K21873 FAM208A; protein TASOR
D K22591 ADNP; activity-dependent neuroprotector homeobox protein
D K22592 AHDC1; AT-hook DNA-binding motif-containing protein 1
D K22593 CHAMP1; chromosome alignment-maintaining phosphoprotein 1
D K22594 POGZ; pogo transposable element with ZNF domain
D K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
D K23220 LRIF1; ligand-dependent nuclear receptor-interacting factor 1
D K24457 SLFN12, SLFN12L; schlafen family member 12
D K24755 WDR76, CMR1; WD repeat-containing protein 76
B Gene silencing
C RISC (RNA-induced silencing complex)
D K11592 DICER1, DCR1; endoribonuclease Dicer [EC:3.1.26.-]
D K11593 ELF2C, AGO; eukaryotic translation initiation factor 2C
D K02156 AUB, PIWI; aubergine
D K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
D K15333 TRM3, TARBP1; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
C piRNA pathway
D K02156 AUB, PIWI; aubergine
D K18405 TDRD1_4_6_7; tudor domain-containing protein 1/4/6/7
D K18406 TDRKH, TDRD2; tudor domain-containing protein 2
D K18407 TDRD5; tudor domain-containing protein 5
D K18408 TDRD9; ATP-dependent RNA helicase TDRD9 [EC:5.6.2.5]
D K18409 TDRD12; ATP-dependent RNA helicase TDRD12 [EC:5.6.2.5]
D K18410 ASZ1, GASZ; ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
D K13982 DDX4, VASA; probable ATP-dependent RNA helicase DDX4 [EC:5.6.2.7]
D K13983 MOV10L1; RNA helicase MOV10L1 [EC:5.6.2.5]
D K18411 MAEL; protein maelstrom
D K18412 TNRC6, GW182; trinucleotide repeat-containing gene 6 protein
D K12618 XRN1, SEP1, KEM1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
D K12614 DDX6, RCK, DHH1; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D K18413 KRIMP; krimper
D K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
D K18414 SQU; squash
D K18415 VRET; vreteno
D K20798 HENMT1; small RNA 2'-O-methyltransferase [EC:2.1.1.386]
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
E K11595 CHP1; chromo domain-containing protein 1
E K11593 ELF2C, AGO; eukaryotic translation initiation factor 2C
E K11597 TAS3; RNA-induced transcriptional silencing complex protein Tas3
D RDRC (RNA-directed RNA polymerase complex)
E K11699 RDR, RDRP; RNA-dependent RNA polymerase [EC:2.7.7.48]
E K11700 CID12; poly(A) RNA polymerase Cid12 [EC:2.7.7.19]
E K11701 HRR1; helicase required for RNAi-mediated heterochromatin assembly 1 [EC:5.6.2.5]
D Other RNAi proteins
E K18416 THEX1, ERI1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E K18418 ERI3, PINT1; ERI1 exoribonuclease 3 [EC:3.1.-.-]
C microRNA pathway
D Microprocessor complex
E K18419 DCGR8; microprocessor complex subunit DGCR8
E K03685 rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
D RISC loading complex
E K11592 DICER1, DCR1; endoribonuclease Dicer [EC:3.1.26.-]
E K11593 ELF2C, AGO; eukaryotic translation initiation factor 2C
E K18420 TARBP2; RISC-loading complex subunit TARBP2
E K24540 PRKRA; interferon-inducible double-stranded RNA-dependent protein kinase activator A
E K18421 R2D2; R2D2
D Other miRNA pathway proteins
E K14289 XPO5; exportin-5
E K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
C Transposable elements
D K23203 THAP1_3; THAP domain-containing protein 1/3
D K23204 THAP2; THAP domain-containing protein 2
D K23205 THAP4; THAP domain-containing protein 4
D K23206 THAP5_8; THAP domain-containing protein 5/8
D K23207 THAP6; THAP domain-containing protein 6
D K23208 THAP7; THAP domain-containing protein 7
D K23209 THAP9; DNA transposase THAP9 [EC:2.7.7.-]
D K23210 THAP10; THAP domain-containing protein 10
D K23211 THAP11; THAP domain-containing protein 11
D K23221 NAIF1; nuclear apoptosis-inducing factor 1
D K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
B Centrosome formation proteins
C Centriole proteins
D K16452 CCDC92; coiled-coil domain-containing protein 92
D K10289 CCNF, FBXO1; F-box protein 1 (cyclin F)
D K16453 CCP110, CEP110; centrosomal protein CEP110
D K16454 CCSAP; centriole, cilia and spindle-associated protein
D K11502 CENPJ; centromere protein J
D K16455 CEP41, TSGA14; centrosomal protein CEP41
D K16456 CEP55; centrosomal protein CEP55
D K16457 CEP76; centrosomal protein CEP76
D K16458 CEP104; centrosomal protein CEP104
D K16459 CEP120; centrosomal protein CEP120
D K16460 CEP128; centrosomal protein CEP128
D K16461 CEP135, CEP4; centrosomal protein CEP135
D K16462 CEP164; centrosomal protein CEP164
D K16463 CEP170; centrosomal protein CEP170
D K16464 CEP250, CNAP1; centrosomal protein CEP250
D K16465 CETN1; centrin-1
D K10840 CETN2; centrin-2
D K16466 CETN3, CDC31; centrin-3
D K16467 CNTLN; centlein
D K16468 CNTROB; centrobin
D K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]
D K16472 HYLS1; hydrolethalus syndrome protein 1
D K16475 LRRCC1, CLERC; leucine-rich repeat and coiled-coil domain-containing protein 1
D K16476 NIN; ninein
D K16477 NINL, NLP; ninein-like protein
D K16479 ODF2; outer dense fiber protein 2
D K16480 OFD1; oral-facial-digital syndrome 1 protein
D K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D K16481 PCNT; pericentrin
D K01047 PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
D K16482 POC1; centriolar protein POC1
D K16483 POC5; centrosomal protein POC5
D K16485 SAS-4; spindle assembly abnormal protein 4
D K16486 SAS-5; spindle assembly abnormal protein 5
D K16487 SAS-6, SASS6; spindle assembly abnormal protein 6
D K16488 SDCCAG8; serologically defined colon cancer antigen 8
D K16489 SFI1; protein SFI1
D K16490 SPICE1; spindle and centriole-associated protein 1
D K16491 STARD9, KIF16A; StAR-related lipid transfer protein 9
D K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C Pericentriolar materials (PCM)
D Centriolar satellite
E K16531 BBS4; Bardet-Biedl syndrome 4 protein
E K16532 CEP72; centrosomal protein CEP72
E K16533 CEP290, NPHP6; centrosomal protein CEP290
E K16534 DISC1; disrupted in schizophrenia 1 protein
E K16535 FOPNL, FOR20; lisH domain-containing protein FOPNL
E K16611 HOOK2; protein HOOK2
E K16536 HOOK3; protein HOOK3
E K16480 OFD1; oral-facial-digital syndrome 1 protein
E K06093 PARD6; partitioning defective protein 6
E K16537 PCM1; pericentriolar material 1 protein
E K16538 PIBF1, CEP90; progesterone-induced-blocking factor 1
E K16539 PLK1S1; centrosomal protein kizuna
E K06085 SSX2IP, ADIP; synovial sarcoma, X breakpoint 2 interacting protein
D Other PCM proteins
E K16540 AZI1, CEP131; 5-azacytidine-induced protein 1
E K16541 CCDC14; coiled-coil domain-containing protein 14
E K16542 CDK5RAP2; CDK5 regulatory subunit-associated protein 2
E K16543 CEP89; centrosomal protein CEP89
E K16544 CEP95; centrosomal protein CEP95
E K16545 DDHD2; phospholipase DDHD2 [EC:3.1.1.-]
E K16546 FGFR10P; FGFR1 oncogene partner
E K16594 LRRC36; leucine-rich repeat-containing protein 36
E K16547 NEDD1; protein NEDD1
E K16548 OAZ1; ornithine decarboxylase antizyme 1
E K16549 PDE4DIP; myomegalin
E K10799 TNKS; tankyrase [EC:2.4.2.30]
C Cyclins
D K06627 CCNA; cyclin-A
D K05868 CCNB1; G2/mitotic-specific cyclin-B1
D K21770 CCNB2; G2/mitotic-specific cyclin-B2
D K21771 CCNB3; G2/mitotic-specific cyclin-B3
D K21777 CCNB; G2/mitotic-specific cyclin-B, other
D K06626 CCNE; G1/S-specific cyclin-E1
D K23964 CCNQ, FAM58A; cyclin-Q
C Kinases and associated factors
D K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
D K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
D K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
D K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
D K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
D K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
D K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
D K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
D K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
D K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
D K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
D K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
D K04345 PKA; protein kinase A [EC:2.7.11.11]
D Kinase anchoring protein
E K16551 AKAP9, AKAP350; A-kinase anchor protein 9
E K21435 ANKRD6; ankyrin repeat domain-containing protein 6
E K24575 MPLKIP; M-phase-specific PLK1-interacting protein
C Microtubules and associated factors
D gamma-tubulin ring complex
E K10389 TUBG; tubulin gamma
E K16569 TUBGCP2, GCP2; gamma-tubulin complex component 2
E K16570 TUBGCP3, GCP3; gamma-tubulin complex component 3
E K16571 TUBGCP4, GCP4; gamma-tubulin complex component 4
E K16572 TUBGCP5, GCP5; gamma-tubulin complex component 5
E K16573 TUBGCP6, GCP6; gamma-tubulin complex component 6
E K16574 MZT2A_B; mitotic-spindle organizing protein 2A/2B
E K16547 NEDD1; protein NEDD1
D Other tubulins
E K07374 TUBA; tubulin alpha
E K07375 TUBB; tubulin beta
E K10390 TUBD; tubulin delta
E K10391 TUBE; tubulin epsilon
D Dynactin complex
E K04648 DCTN1; dynactin 1
E K10424 DCTN2; dynactin 2
E K10425 DCTN3; dynactin 3
E K10426 DCTN4; dynactin 4
E K10427 DCTN5; dynactin 5
E K10428 DCTN6; dynactin 6
E K16575 ACTR1, ARP1; centractin
E K16576 ACTR10, ARP11; actin-related protein 10
D BRISC complex
E K20799 FAM175B, ABRO1; BRISC complex subunit Abro1
E K20776 BABAM, NBA1, MERIT40; BRISC and BRCA1-A complex member 1
E K11864 BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
E K12173 BRE, BRCC45; BRCA1-A complex subunit BRE
D Microtubule-associated proteins
E K10421 CLIP1, RSN; CAP-Gly domain-containing linker protein 1
E K16578 CLASP1_2; CLIP-associating protein 1/2
E K16579 DCX; neuronal migration protein doublecortin
E K10436 MAPRE; microtubule-associated protein, RP/EB family
E K19573 ATAT1, MEC17; alpha-tubulin N-acetyltransferase 1 [EC:2.3.1.108]
E K16580 SLAIN1_2; SLAIN motif-containing protein 1/2
E K20873 NEK3; serine/threonine-protein kinase Nek3 [EC:2.7.11.1]
E K23400 DCDC1; doublecortin domain-containing protein 1
E K25867 TPPP; tubulin polymerization-promoting protein [EC:3.6.5.-]
E K25872 TPPP3; tubulin polymerization-promoting protein family member 3
E K26165 CSTPP1; centriolar satellite-associated tubulin polyglutamylase complex regulator 1
E K26156 KIF18B; kinesin family member 18B
E K26787 MARVELD1; MARVEL domain-containing protein 1
C Augmin complex
D K16584 HAUS1, AUG1; HAUS augmin-like complex subunit 1
D K16585 HAUS2, AUG2; HAUS augmin-like complex subunit 2
D K16586 HAUS3, AUG3; HAUS augmin-like complex subunit 3
D K16587 HAUS4, AUG4; HAUS augmin-like complex subunit 4
D K16588 HAUS5, AUG5; HAUS augmin-like complex subunit 5
D K16589 HAUS6, AUG6; HAUS augmin-like complex subunit 6
D K16590 HAUS7, AUG7, UIP1; HAUS augmin-like complex subunit 7
D K16591 HAUS8; HAUS augmin-like complex subunit 8
D K25918 AUG8; augmin complex subunit 8
C Centrosome duplication proteins
D Centriole replication proteins
E K16714 ANA1; anastral spindle 1
E K16715 ANA2; anastral spindle 2
E K02183 CALM; calmodulin
E K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
E K16453 CCP110, CEP110; centrosomal protein CEP110
E K11502 CENPJ; centromere protein J
E K16717 CEP97; centrosomal protein CEP97
E K16461 CEP135, CEP4; centrosomal protein CEP135
E K16728 CEP152, ASL; centrosomal protein CEP152
E K10840 CETN2; centrin-2
E K16718 CNN; centrosomin
E K16468 CNTROB; centrobin
E K16480 OFD1; oral-facial-digital syndrome 1 protein
E K16719 KANSL3, RCD1; regulatory NSL complex subunit 3
E K16720 RCD2; reduction in cnn dots 2
E K16721 RCD4; reduction in cnn dots 4
E K16485 SAS-4; spindle assembly abnormal protein 4
E K16487 SAS-6, SASS6; spindle assembly abnormal protein 6
E K16722 SPD2; spindle-defective protein 2
E K16724 STIL; SCL-interrupting locus protein
D Regulators of centriole replication
E K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E K10683 BARD1; BRCA1-associated RING domain protein 1
E K19788 OLA1; obg-like ATPase 1
E K16542 CDK5RAP2; CDK5 regulatory subunit-associated protein 2
E K16457 CEP76; centrosomal protein CEP76
E K16725 CEP192; centrosomal protein CEP192
E K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
E K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
E K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
E K07936 RAN; GTP-binding nuclear protein Ran
E K14290 XPO1, CRM1; exportin-1
E K11276 NPM1; nucleophosmin 1
E K26160 CENATAC; centrosomal AT-AC splicing factor
D Other centrosome duplication proteins
E K16726 ANKRD17, MASK; ankyrin repeat domain-containing protein 17
E K16727 ARHGEF10; Rho guanine nucleotide exchange factor 10
E K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
E K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
E K16541 CCDC14; coiled-coil domain-containing protein 14
E K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
E K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
E K10727 CDT1; chromatin licensing and DNA replication factor 1
E K16729 CHORDC1, CHP1; cysteine and histidine-rich domain-containing protein
E K12869 CRN, CRNKL1, CLF1, SYF3; crooked neck
E K10263 FBXW5; F-box and WD-40 domain protein 5
E K04402 GADD45; growth arrest and DNA-damage-inducible protein
E K16731 GOLGA1; golgin subfamily A member 1
E K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
E K02209 MCM5, CDC46; DNA replication licensing factor MCM5 [EC:5.6.2.3]
E K02603 ORC1; origin recognition complex subunit 1
E K02604 ORC2; origin recognition complex subunit 2
E K02605 ORC3; origin recognition complex subunit 3
E K16732 PRC1, ASE1, MAP65; Ase1/PRC1/MAP65 family protein
E K16733 RACGAP1, Tum; Rac GTPase-activating protein 1
E K16734 SAC3D1, SHD1; SAC3 domain-containing protein 1
E K26251 CEP295; centrosomal protein CEP295
C Nde1-Su48 complex
D K11674 MCRS1, INO80Q; microspherule protein 1
D K16737 ZNF365, Su48; protein ZNF365
D K16738 NDE1, NUDE; nuclear distribution protein NudE
D K16739 NDEL1; nuclear distribution protein NudE-like 1
C LINC complex
D K19326 SYNE1; nesprin-1
D K19346 SYNE2; nesprin-2
D K21761 SYNE3; nesprin-3
D K23401 SYNE4; nesprin-4
D K19347 SUN1_2; SUN domain-containing protein 1/2
D K21874 SUN3; SUN domain-containing protein 3
D K21875 SPAG4, SUN4; sperm-associated antigen 4 protein
D K21876 SUN5; SUN domain-containing protein 5
D K22595 CCDC155, KASH5; protein KASH5
C 3M complex
D K10613 CUL7; cullin 7
D K17561 CCDC8; coiled-coil domain-containing protein 8
D K19574 OBSL1; obscurin-like protein 1
C Other centriole associated proteins
D K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D K16741 ALMS1; alstrom syndrome protein 1
D K04575 ALS2; amyotrophic lateral sclerosis 2 protein
D K02085 APC; adenomatosis polyposis coli protein
D K07943 ARL2; ADP-ribosylation factor-like protein 2
D K16742 ARL2BP, BART; ADP-ribosylation factor-like protein 2-binding protein
D K16743 ASPM, ASP; abnormal spindle-like microcephaly-associated protein
D K04385 AXIN2; axin 2
D K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
D K16756 BICDL, CCDC64; BICD family-like cargo adapter
D K16750 BLOC1S2; biogenesis of lysosome-related organelles complex 1 subunit 2
D K16751 C2CD3; C2 domain-containing protein 3
D K16752 CCDC15; coiled-coil domain-containing protein 15
D K16753 CCDC34; coiled-coil domain-containing protein 34
D K16755 CCDC61; coiled-coil domain-containing protein 61
D K16757 CCDC77; coiled-coil domain-containing protein 77
D K23693 CCDC78; coiled-coil domain-containing protein 78
D K16758 CCDC85B; coiled-coil domain-containing protein 85B
D K16759 CCDC102; coiled-coil domain-containing protein 102
D K16760 CCHCR1; coiled-coil alpha-helical rod protein 1
D K04393 CDC42; cell division control protein 42
D K06736 CDH2, CDHN, CD325; cadherin 2, type 1, N-cadherin
D K06808 CDH13; cadherin 13, H-cadherin
D K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
D K16761 CEP44; centrosomal protein CEP44
D K16762 CEP57; centrosomal protein CEP57
D K16763 CEP63; centrosomal protein CEP63
D K16764 CEP68; centrosomal protein CEP68
D K16765 CEP78; centrosomal protein CEP78
D K16754 CEP83, CCDC41; centrosomal protein CEP83
D K16766 CEP85; centrosomal protein CEP85
D K16767 CEP112; centrosomal protein CEP112
D K16768 CEP350; centrosomal protein CEP350
D K08106 CHST15; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
D K16769 CKAP2; cytoskeleton-associated protein 2
D K16770 CNTRL; centriolin
D K16771 CSPP1; centrosome and spindle pole-associated protein 1
D K12076 DLG1; disks large protein 1
D K15008 DLGAP1, GKAP; discs, large-associated protein 1
D K07195 EXOC7, EXO70; exocyst complex component 7
D K16773 FATS; fragile-site associated tumor suppressor
D K07192 FLOT; flotillin
D K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D K19403 MCPH1; microcephalin
D K16775 MPHOSPH9, MPP9; M-phase phosphoprotein 9
D K16776 NAV1; neuron navigator 1
D K16777 NEURL4; neuralized-like protein 4
D K15608 PAX2; paired box protein 2
D K16493 PCDHA; protocadherin alpha
D K16778 PDPN; podoplanin
D K16779 RAB3IP, RABIN8; Rab-3A-interacting protein
D K07901 RAB8A, MEL; Ras-related protein Rab-8A
D K16780 SSNA1; sjoegren syndrome nuclear autoantigen 1
D K21762 WDR62; WD repeat-containing protein 62
D K25164 WRAP73, WDR8; WD repeat-containing protein WRAP73
D K21763 MAPKBP1; mitogen-activated protein kinase binding protein 1
D K21764 SPAG5; sperm-associated antigen 5
D K21765 MNR; protein moonraker
D K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
C Spindle formation proteins
D K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D K16800 AUNIP, AIBP; aurora kinase A and ninein-interacting protein
D K16454 CCSAP; centriole, cilia and spindle-associated protein
D K16801 CEP19; centrosomal protein CEP19
D K16802 CEP70; centrosomal protein CEP70
D K16803 CKAP5; cytoskeleton-associated protein 5
D K15433 CGI99, CLE7, RLLM1; RLL motif containing protein 1
D K18423 CSE1, CAS, XPO2; exportin-2 (importin alpha re-exporter)
D K16771 CSPP1; centrosome and spindle pole-associated protein 1
D K16804 DLGAP5, DLG7; disks large-associated protein 5
D K16805 FAM83D, CHICA; protein FAM83D
D K15837 GPSM2; G-protein signaling modulator 2
D K10393 KIF2_24, MCAK; kinesin family member 2/24
D K10398 KIF11, EG5; kinesin family member 11
D K10402 KIF20; kinesin family member 20
D K17387 KIF23; kinesin family member 23
D K10405 KIFC1; kinesin family member C1
D K23940 KPNA1; importin subunit alpha-5
D K15043 KPNA2_7; importin subunit alpha-1/8
D K15042 KPNA5_6; importin subunit alpha-6/7
D K14293 KPNB1, IPO1; importin subunit beta-1
D K16806 MAP7D1; MAP7 domain-containing protein 1
D K16807 MAP7D3; MAP7 domain-containing protein 3
D K16808 NUMA1; nuclear mitotic apparatus protein 1
D K14302 NUP37; nuclear pore complex protein Nup37
D K14305 NUP43; nuclear pore complex protein Nup43
D K14304 NUP85; nuclear pore complex protein Nup85
D K14297 NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
D K14301 NUP107, NUP84; nuclear pore complex protein Nup107
D K14300 NUP133; nuclear pore complex protein Nup133
D K14303 NUP160, NUP120; nuclear pore complex protein Nup160
D K14310 NUP205, NUP192; nuclear pore complex protein Nup205
D K20724 TMEM33; transmembrane protein 33
D K20721 RTN1; reticulon-1
D K20722 RTN2; reticulon-2
D K20723 RTN3; reticulon-3
D K20720 RTN4; reticulon-4
D K16794 PAFAH1B1, LIS1; platelet-activating factor acetylhydrolase IB subunit alpha
D K14298 RAE1, GLE2; mRNA export factor
D K07936 RAN; GTP-binding nuclear protein Ran
D K16491 STARD9, KIF16A; StAR-related lipid transfer protein 9
D K16810 TBCCD1; TBCC domain-containing protein 1
D K16811 TCHP; trichoplein keratin filament-binding protein
D K16812 TPX2; targeting protein for Xklp2
D K19865 PKHD1; fibrocystin
D K20875 NEK6; serine/threonine-protein kinase Nek6 [EC:2.7.11.34]
D K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
D K20878 NEK9, NERCC1; serine/threonine-protein kinase Nek9 [EC:2.7.11.1]
D K21441 ANKRD53; ankyrin repeat domain-containing protein 53
D K21443 PSRC1; proline/serine-rich coiled-coil protein 1
D K17082 FERMT1, KIND1; kindlin 1
D K26166 NUSAP1; nucleolar and spindle-associated protein 1
D K26673 FIGN; fidgetin
D K24394 STU2; protein STU2
B Sister chromatid separation proteins
C Securin and associated proteins
D K06635 PTTG; securin
D K26099 PTTG1IP; PTTG1-interacting protein
D K16828 PIM; pimples
D K16829 THR; protein three rows
C Separase
D K02365 ESP1; separase [EC:3.4.22.49]
C APC/C complex
D K03348 APC1, ANAPC1; anaphase-promoting complex subunit 1
D K03349 APC2, ANAPC2; anaphase-promoting complex subunit 2
D K03350 APC3, CDC27; anaphase-promoting complex subunit 3
D K03351 APC4, ANAPC4; anaphase-promoting complex subunit 4
D K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
D K03353 APC6, CDC16; anaphase-promoting complex subunit 6
D K03354 APC7, ANAPC7; anaphase-promoting complex subunit 7
D K03355 APC8, CDC23; anaphase-promoting complex subunit 8
D K03356 APC9; anaphase-promoting complex subunit 9
D K03357 APC10, ANAPC10, DOC1; anaphase-promoting complex subunit 10
D K03358 APC11, ANAPC11; anaphase-promoting complex subunit 11
D K03359 APC12, CDC26; anaphase-promoting complex subunit 12
D K12456 APC13, ANAPC13; anaphase-promoting complex subunit 13
D K12416 SWM1, APC13; anaphase-promoting complex subunit SWM1
D K25228 APC15, ANAPC15; anaphase-promoting complex subunit 15
D K25229 APC16, ANAPC16; anaphase-promoting complex subunit 16
D K03363 CDC20; cell division cycle 20, cofactor of APC complex
C Aurora kinases
D K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D K11479 AURKB; aurora kinase B [EC:2.7.11.1]
D K11480 AURKC; aurora kinase C [EC:2.7.11.1]
D K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
D Regulators of Aurora kinases
E K16682 AJUBA, LIMD1, WTIP; LIM domain-containing protein
E K16830 AURKAIP1; aurora kinase A-interacting protein
E K16831 BORA; protein aurora borealis
E K04402 GADD45; growth arrest and DNA-damage-inducible protein
E K16832 NEDD9, HEF1, CASL; enhancer of filamentation 1
E K16833 PPP1R2, IPP2; protein phosphatase inhibitor 2
E K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
E K16812 TPX2; targeting protein for Xklp2
E K04451 TP53, P53; tumor protein p53
C TACC proteins
D K14281 TACC1; transforming acidic coiled-coil-containing protein 1
D K14282 TACC2; transforming acidic coiled-coil-containing protein 2
D K14283 TACC3, maskin; transforming acidic coiled-coil-containing protein 3
C Polo kinases
D K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
D K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
D K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
C Early mitotic inhibitors
D K10292 FBXO5, EMI1; F-box protein 5
D K10318 FBXO43, EMI2; F-box protein 43
B Chromatin remodeling factors
C BAF complex
D K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
D K05692 ACTB_G1; actin beta/gamma 1
D K11340 ACTL6A, INO80K; actin-like protein 6A
D K11652 ACTL6B; actin-like protein 6B
D K25605 BCL7; B-cell CLL/lymphoma 7 protein
D K11653 ARID1; AT-rich interactive domain-containing protein 1
D K15623 SS18, SSXT, SYT, CREST; protein SSXT
D K22198 BAF45B_C, DPF1_3; BRG1-associated factor 45B/C
D K13196 DPF2, REQ; zinc finger protein ubi-d4
C PBAF complex
D K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
D K05692 ACTB_G1; actin beta/gamma 1
D K11340 ACTL6A, INO80K; actin-like protein 6A
D K11652 ACTL6B; actin-like protein 6B
D K25605 BCL7; B-cell CLL/lymphoma 7 protein
D K11765 ARID2; AT-rich interactive domain-containing protein 2
D K11757 PBRM1, PB1; protein polybromo-1
D K11723 BRD7; bromodomain-containing protein 7
D K22197 BAF45A, PHF10; BRG1-associated factor 45A
C GBAF(ncBAF) complex
D K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D K11340 ACTL6A, INO80K; actin-like protein 6A
D K11652 ACTL6B; actin-like protein 6B
D K05692 ACTB_G1; actin beta/gamma 1
D K25605 BCL7; B-cell CLL/lymphoma 7 protein
D K15623 SS18, SSXT, SYT, CREST; protein SSXT
D K22184 BRD9; bromodomain-containing protein 9
D K25612 BICRA, GLTSCR1; BRD4-interacting chromatin-remodeling complex-associated protein
D K25613 BICRAL, GLTSCR1L; BRD4-interacting chromatin-remodeling complex-associated protein-like
C CHRAC complex
D K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D K11655 BAZ1A, ACF1; bromodomain adjacent to zinc finger domain protein 1A
D K11656 CHRAC1, CHRAC15; chromatin accessibility complex protein 1
D K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C RSF complex
D K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D K11657 RSF1; remodeling and spacing factor 1
C WICH complex
D K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D K11658 BAZ1B, WSTF; bromodomain adjacent to zinc finger domain protein 1B
C B-WICH complex
D K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D K11658 BAZ1B, WSTF; bromodomain adjacent to zinc finger domain protein 1B
D K16911 DDX21; ATP-dependent RNA helicase DDX21 [EC:5.6.2.7]
D K17046 DEK; protein DEK
D K10841 ERCC6, CSB, RAD26; DNA excision repair protein ERCC-6
D K10356 MYO1; myosin I
D K02331 POL5, MYBBP1A; DNA polymerase phi [EC:2.7.7.7]
D K12828 SF3B1, SAP155; splicing factor 3B subunit 1
C NORC complex
D K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D K15224 BAZ2A, TIP5; bromodomain adjacent to zinc finger domain protein 2A
C BRF complex
D K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D K26167 BAZ2B; bromodomain adjacent to zinc finger domain protein 2B
C NuRD complex
D K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D K11642 CHD3, MI2A; chromodomain-helicase-DNA-binding protein 3 [EC:5.6.2.-]
D K11643 CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
D K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
D K11659 RBBP7; histone-binding protein RBBP7
D K11660 MTA; metastasis-associated protein MTA
D K11591 MBD3; methyl-CpG-binding domain protein 3
D K23194 GATAD2; transcriptional repressor p66
D K23310 PHF6; PHD finger protein 6
D K26454 CDK2AP1; cyclin-dependent kinase 2-associated protein 1
D K26455 CDK2AP2; cyclin-dependent kinase 2-associated protein 2
C NuRF complex
D K11727 SMARCA1, SNF2L; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 [EC:5.6.2.-]
D K11728 BPTF, E(bx); nucleosome-remodeling factor subunit BPTF
D K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
D K11659 RBBP7; histone-binding protein RBBP7
D K23406 BAP18; chromatin complexes subunit BAP18
C NuRF complex (fruit fly)
D K11654 SMARCA5, SNF2H, ISWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D K11728 BPTF, E(bx); nucleosome-remodeling factor subunit BPTF
D K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
D K11726 NURF38; nucleosome-remodeling factor 38 kDa subunit [EC:3.6.1.1]
C CERF complex
D K11727 SMARCA1, SNF2L; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 [EC:5.6.2.-]
D K25830 CECR2; cat eye syndrome critical region protein 2
C SRCAP complex
D K11661 SRCAP, SWR1; helicase SRCAP/SWR1 [EC:5.6.2.-]
D K11340 ACTL6A, INO80K; actin-like protein 6A
D K11662 ACTR6, ARP6; actin-related protein 6
D K04499 RUVBL1, RVB1, INO80H; RuvB-like protein 1 [EC:5.6.2.4]
D K11338 RUVBL2, RVB2, INO80J; RuvB-like protein 2 [EC:5.6.2.3]
D K11324 DMAP1, SWC4, EAF2; DNA methyltransferase 1-associated protein 1
D K11341 YEATS4, GAS41, YAF9; YEATS domain-containing protein 4
D K11663 ZNHIT1, VPS71; zinc finger HIT domain-containing protein 1
D K11664 VPS72, TCFL1, YL1; vacuolar protein sorting-associated protein 72
C INO80 complex
D K11665 INO80, INOC1; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D K11666 INO80B, ZNHIT4, PAPA1; INO80 complex subunit B
D K11667 INO80C, IES6; INO80 complex subunit C
D K11668 INO80D; INO80 complex subunit D
D K11669 INO80E; INO80 complex subunit E
D K11670 TEPT, INO80F; TCF3 fusion partner
D K11671 NFRKB, INO80G; nuclear factor related to kappa-B-binding protein
D K04499 RUVBL1, RVB1, INO80H; RuvB-like protein 1 [EC:5.6.2.4]
D K11338 RUVBL2, RVB2, INO80J; RuvB-like protein 2 [EC:5.6.2.3]
D K11340 ACTL6A, INO80K; actin-like protein 6A
D K11672 ACTR5, ARP5, INO80M; actin-related protein 5
D K11673 ACTR8, ARP8, INO80N; actin-related protein 8
D K11674 MCRS1, INO80Q; microspherule protein 1
C INO80 complex (yeast)
D K11665 INO80, INOC1; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D K11675 IES1; Ino eighty subunit 1
D K11676 IES2; Ino eighty subunit 2
D K11677 IES3; Ino eighty subunit 3
D K11678 IES4; Ino eighty subunit 4
D K11679 IES5; Ino eighty subunit 5
D K11667 INO80C, IES6; INO80 complex subunit C
D K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
D K11680 NHP10; non-histone protein 10
D K04499 RUVBL1, RVB1, INO80H; RuvB-like protein 1 [EC:5.6.2.4]
D K11338 RUVBL2, RVB2, INO80J; RuvB-like protein 2 [EC:5.6.2.3]
D K11400 ARP4; actin-related protein 4
D K11672 ACTR5, ARP5, INO80M; actin-related protein 5
D K11673 ACTR8, ARP8, INO80N; actin-related protein 8
C RSC complex
D K11756 RSC1_2; chromatin structure-remodeling complex subunit RSC1/2
D K11758 RSC3_30; chromatin structure-remodeling complex subunit RSC3/30
D K11759 RSC4; chromatin structure-remodeling complex subunit RSC4
D K11760 RSC6; chromatin structure-remodeling complex subunit RSC6
D K11761 NPL6, RSC7; chromatin structure-remodeling complex protein RSC7
D K11762 RSC8, SWH3, SSR2; chromatin structure-remodeling complex subunit RSC8
D K11763 RSC9; chromatin structure-remodeling complex subunit RSC9
D K11764 LDB7, RSC14; chromatin structure-remodeling complex protein RSC14
D K11766 RSC58; chromatin structure-remodeling complex subunit RSC58
D K11767 ARP7, SWP61; actin-related protein 7
D K11768 ARP9, SWP59; actin-related protein 9
D K11769 HTL1; chromatin structure-remodeling complex protein HTL1
D K11770 SFH1; chromatin structure-remodeling complex subunit SFH1
D K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
C SWI/SNF complex
D K11771 SWI1, ADR6; SWI/SNF chromatin-remodeling complex subunit SWI1
D K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
D K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D K11772 SWI3; SWI/SNF complex subunit SWI3
D K11773 SNF6; SWI/SNF complex component SNF6
D K11774 SNF11; SWI/SNF complex component SNF11
D K11775 SNF12, SWP73; SWI/SNF complex component SWP73
D K11776 SWP82; SWI/SNF complex component SWP82
D K11767 ARP7, SWP61; actin-related protein 7
D K11768 ARP9, SWP59; actin-related protein 9
D K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
C SWR1 complex
D K11661 SRCAP, SWR1; helicase SRCAP/SWR1 [EC:5.6.2.-]
D K05692 ACTB_G1; actin beta/gamma 1
D K11400 ARP4; actin-related protein 4
D K04499 RUVBL1, RVB1, INO80H; RuvB-like protein 1 [EC:5.6.2.4]
D K11338 RUVBL2, RVB2, INO80J; RuvB-like protein 2 [EC:5.6.2.3]
D K11662 ACTR6, ARP6; actin-related protein 6
D K11341 YEATS4, GAS41, YAF9; YEATS domain-containing protein 4
D K11663 ZNHIT1, VPS71; zinc finger HIT domain-containing protein 1
D K11664 VPS72, TCFL1, YL1; vacuolar protein sorting-associated protein 72
D K11682 SWC3; SWR1-complex protein 3
D K11324 DMAP1, SWC4, EAF2; DNA methyltransferase 1-associated protein 1
D K11683 SWC7; SWR1-complex protein 7
D K11684 BDF1; bromodomain-containing factor 1
C ASTRA complex
D K08874 TRRAP; transformation/transcription domain-associated protein
D K04499 RUVBL1, RVB1, INO80H; RuvB-like protein 1 [EC:5.6.2.4]
D K11338 RUVBL2, RVB2, INO80J; RuvB-like protein 2 [EC:5.6.2.3]
D K11137 TELO2, TEL2; telomere length regulation protein
D K20403 TTI1; TELO2-interacting protein 1
D K24771 TTI2; TEL2-interacting protein 2
D K24767 ASA1; ASTRA-associated protein 1
C Other chromatin remodeling factors
D K08871 BRD2; bromodomain-containing protein 2
D K11721 BRD3; bromodomain-containing protein 3
D K11722 BRD4; bromodomain-containing protein 4
D K11724 BRDT; bromodomain testis-specific protein
D K20091 CHD2; chromodomain-helicase-DNA-binding protein 2 [EC:5.6.2.-]
D K14435 CHD5; chromodomain-helicase-DNA-binding protein 5 [EC:5.6.2.-]
D K14436 CHD6; chromodomain-helicase-DNA-binding protein 6 [EC:5.6.2.-]
D K14437 CHD7; chromodomain-helicase-DNA-binding protein 7 [EC:5.6.2.-]
D K04494 CHD8, HELSNF1; chromodomain helicase DNA binding protein 8 [EC:5.6.2.-]
D K14438 CHD9; chromodomain-helicase-DNA-binding protein 9 [EC:5.6.2.-]
D K20092 CHD1L; chromodomain-helicase-DNA-binding protein 1-like [EC:5.6.2.-]
D K23195 CTCF, CTCFL; transcriptional repressor CTCF
D K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
D K14440 SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-]
D K19001 HELLS, DDM1; ATP-dependent DNA helicase
D K23408 CDCA7, CDCA7L, JPO1; cell division cycle-associated protein 7
D K17492 UBN; ubinuclein
D K21412 ANKLE2, LEM4; ankyrin repeat and LEM domain-containing protein 2
D K23225 SATB1; DNA-binding protein SATB1
D K23226 SATB2; DNA-binding protein SATB2
D K23196 ZBTB18_42; zinc finger and BTB domain-containing protein 18/42
D K23803 YY1AP1; YY1-associated protein 1
D K24135 MORC; MORC family CW-type zinc finger protein
D K25816 CCAR2, DBC1; cell cycle and apoptosis regulator protein 2
D K25831 LUZP1; leucine zipper protein 1
D K26100 PWWP2; PWWP domain-containing protein 2
D K27104 ZNF827; zinc finger protein 827
D K26273 SBNO, SNO, FGT1; protein strawberry notch
D K26796 HmgD_Z; high mobility group protein D/Z
D K25868 EBS, SHL; chromatin remodeling protein
#
AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
D K03746 hns; DNA-binding protein H-NS
D K11685 stpA; DNA-binding protein StpA
D K24450 hmf, hmt; DNA-binding protein
D K26248 rok; repressor Rok
D K26249 lsr2; nucleoid-associated protein Lsr2
C HU (heat unstable protein)
D K05787 hupA; DNA-binding protein HU-alpha
D K03530 hupB; DNA-binding protein HU-beta
C IHF (integration host factor)
D K04764 ihfA, himA; integration host factor subunit alpha
D K05788 ihfB, himD; integration host factor subunit beta
C Other nucleoid associated proteins
D K05516 cbpA; curved DNA-binding protein
D K18997 cbpM; chaperone modulatory protein CbpM
D K05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator
D K02313 dnaA; chromosomal replication initiator protein
D K12961 diaA; DnaA initiator-associating protein
D K11940 hspQ; heat shock protein HspQ
D K04047 dps; starvation-inducible DNA-binding protein
D K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D K03666 hfq; host factor-I protein
D K05596 iciA; LysR family transcriptional regulator, chromosome initiation inhibitor
D K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D K06899 ndpA; nucleoid-associated protein
B Chromosome partitioning proteins
C MukBEF complex
D K03632 mukB; chromosome partition protein MukB
D K03804 mukE; chromosome partition protein MukE
D K03633 mukF; chromosome partition protein MukF
C Condensin-like complex
D K03529 smc; chromosome segregation protein
D K05896 scpA; segregation and condensation protein A
D K06024 scpB; segregation and condensation protein B
D K24719 sph1; smc-like protein Sph1
C Divisome proteins
D K03590 ftsA; cell division protein FtsA
D K05589 ftsB; cell division protein FtsB
D K13052 divIC, divA; cell division protein DivIC
D K09812 ftsE; cell division transport system ATP-binding protein
D K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D K03466 ftsK, spoIIIE; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D K03586 ftsL; cell division protein FtsL
D K03591 ftsN; cell division protein FtsN
D K03589 ftsQ; cell division protein FtsQ
D K03588 ftsW, spoVE; cell division protein FtsW
D K09811 ftsX; cell division transport system permease protein
D K03531 ftsZ; cell division protein FtsZ
D K03528 zipA; cell division protein ZipA
D K09888 zapA; cell division protein ZapA
D K09892 zapB; cell division protein ZapB
D K18657 zapC; cell division protein ZapC
D K18778 zapD; cell division protein ZapD
D K06916 zapE; cell division protein ZapE
D K07269 ytfB; cell division protein YtfB
D K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D K03585 acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system
C Inhibitors of FtsZ assembly
D K06286 ezrA; septation ring formation regulator
D K03610 minC; septum site-determining protein MinC
D K03609 minD; septum site-determining protein MinD
D K03608 minE; cell division topological specificity factor
D K04074 divIVA; cell division initiation protein
D K13053 sulA; cell division inhibitor SulA
D K09772 sepF; cell division inhibitor SepF
D K05501 slmA, ttk; TetR/AcrR family transcriptional regulator
C Other chromosome partitioning proteins
D K03645 seqA; negative modulator of initiation of replication
D K03569 mreB; rod shape-determining protein MreB and related proteins
D K03570 mreC; rod shape-determining protein MreC
D K03571 mreD; rod shape-determining protein MreD
D K05837 rodA, mrdB; rod shape determining protein RodA
D K03496 parA, soj; chromosome partitioning protein
D K03497 parB, spo0J; ParB family transcriptional regulator, chromosome partitioning protein
D K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D K03495 gidA, mnmG, MTO1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D K03501 gidB, rsmG; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D K04094 trmFO, gid; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D K03733 xerC; integrase/recombinase XerC
D K04763 xerD; integrase/recombinase XerD
D K11686 racA; chromosome-anchoring protein RacA
D K02499 yabN; tetrapyrrole methylase family protein / MazG family protein
D K03593 mrp, NUBPL; ATP-binding protein involved in chromosome partitioning
D K04095 fic, FICD, HYPE; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
D K03978 engB; GTP-binding protein
D K09762 whiA; cell division protein WhiA
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 16, 2024