+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Ralstonia pickettii 12D</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
D      Cap binding complex
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
D      Pre-mRNA cleavage factor IIm (CFIIm)
D      Cleavage and polyadenylation specificity factor (CPSF) complex
D      Cleavage stimulation factor (CSTF) complex
D      U7-dependent histone pre-mRNA processing factors
D      DRB sensitivity inducing factor (DSIF) complex
D      N6-methyltransferase complex
D      Poly(A) addition factors
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
D      TREX complex
D      TREX-2 complex
D      Nuclear pore complex
D      Ran-mediated transport factors
D      eIF4F and regulatory proteins
D      APOBEC1-ACF complex
D      Other transport factors
C    Surveillance factors
D      Surveillance complex
D      Protein phosphatase 2A
D      Other surveillance factors
C    Factors involved in mRNA localization
D      Cargo complex
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
D      Other mRNA localization factors
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
D      P-body specific factors
D      Stress granule specific factors
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
D      Lsm complex
D      5' exonucleases
D      Other 5'-3' decay factors
C    3'-5' decay
D      Core exosome factors
D      Exosome cofactors
D      TRAMP complex
D      Ski complex
D      Ccr4-NOT complex
D      Pan complex
D      Other 3'-5' decay factors
C    Other degradation factors
D      RNases
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A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        Rpic12D_0970 ribonuclease, Rne/Rng family	K08300 rne; ribonuclease E [EC:3.1.26.12] 
E        Rpic12D_1995 ribonuclease, Rne/Rng family	K08301 rng; ribonuclease G [EC:3.1.26.-] 
E        Rpic12D_0993 ribonuclease III	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        Rpic12D_1164 ribonuclease R	K12573 rnr; ribonuclease R [EC:3.1.13.1] 
E        Rpic12D_2602 guanine-specific ribonuclease N1 and T1	K01167 rnaSA; ribonuclease T1 [EC:4.6.1.24] 
E        Rpic12D_0884 Exonuclease RNase T and DNA polymerase III	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
E        Rpic12D_0434 DEAD/DEAH box helicase domain protein	K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] 
E        Rpic12D_2015 DEAD/DEAH box helicase domain protein	K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] 
E        Rpic12D_2958 ATP-dependent DNA helicase RecQ	K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] 
D      Other RNA degradosome components
E        Rpic12D_1068 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        Rpic12D_1896 Polyribonucleotide nucleotidyltransferase	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        Rpic12D_1123 transcription termination factor Rho	K03628 rho; transcription termination factor Rho 
C    Other RNA degradation factors
D      Chaperones
E        Rpic12D_2464 chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK 
E        Rpic12D_0535 chaperonin GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        Rpic12D_3081 chaperonin GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        Rpic12D_3576 chaperonin GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        Rpic12D_4533 chaperonin GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        Rpic12D_1156 RNA chaperone Hfq	K03666 hfq; host factor-I protein 
D      Others
E        Rpic12D_1711 Polyphosphate kinase	K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] 
E        Rpic12D_3243 protein of unknown function DUF344	K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] 
E        Rpic12D_5312 protein of unknown function DUF344	K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] 
E        Rpic12D_2456 poly(A) polymerase	K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] 
E        Rpic12D_2652 NUDIX hydrolase	K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] 
E        Rpic12D_1292 regulator of ribonuclease activity A	K02553 rraA; regulator of ribonuclease activity A 
E        Rpic12D_0285 conserved hypothetical protein	K06958 rapZ; RNase adapter protein RapZ 
E        Rpic12D_1171 ATP-dependent helicase HrpA	K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6] 
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
D      Cofactors
D      Others
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#Last updated: March 26, 2026