+E Replication protein KO
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DNA Replication Proteins - Mycosarcoma maydis
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D UMAG_06087 hypothetical protein K02603 ORC1; origin recognition complex subunit 1
D UMAG_00728 hypothetical protein K02606 ORC4; origin recognition complex subunit 4
D UMAG_01191 hypothetical protein K02607 ORC5; origin recognition complex subunit 5
D UMAG_03496 hypothetical protein K02213 CDC6; cell division control protein 6
D UMAG_01445 putative MCM DNA helicase complex subunit MCM2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D UMAG_01679 putative pre-replication complex, subunit K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D UMAG_01646 putative replication licensing factor MCM4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D UMAG_05064 putative MCM DNA helicase complex subunit MCM5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D UMAG_00366 putative replication-related protein K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D UMAG_06402 putative mini-chromosome maintenance complex protein 7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
D UMAG_10237 hypothetical protein K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D UMAG_00389 hypothetical protein K02309 DBF4; regulatory subunit for Cdc7p protein kinase
C GINS complex
D UMAG_04927 hypothetical protein K10732 GINS1; GINS complex subunit 1
D UMAG_11652 hypothetical protein K10733 GINS2; GINS complex subunit 2
D UMAG_10100 hypothetical protein K10734 GINS3; GINS complex subunit 3
D UMAG_10318 hypothetical protein K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D UMAG_00290 hypothetical protein K03507 DPB11; DNA replication regulator DPB11
D UMAG_05770 TSD2 protein, required for DNA replication K06628 CDC45; cell division control protein 45
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D UMAG_04529 hypothetical protein K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D UMAG_02557 hypothetical protein K02321 POLA2; DNA polymerase alpha subunit B
D UMAG_10656 hypothetical protein K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D UMAG_03852 hypothetical protein K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D UMAG_01008 putative DNA polymerase epsilon, calytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D UMAG_02760 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D UMAG_05207 hypothetical protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D UMAG_01458 putative DNA-directed DNA polymerase delta POL3 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D UMAG_04976 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
D UMAG_03766 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D UMAG_00527 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D UMAG_11745 hypothetical protein K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
C RPA (replication protein A)
D UMAG_05156 putative Replication factor-A protein 1 K07466 RFA1; replication factor A1
D UMAG_02579 hypothetical protein K10739 RFA2; replication factor A2
D UMAG_04165 hypothetical protein K10740 RPA3; replication factor A3
C RFC (replication factor C)
D UMAG_03434 hypothetical protein K10754 RFC1; replication factor C subunit 1
D UMAG_00216 putative DNA replication factor C subunit protein K10755 RFC2_4; replication factor C subunit 2/4
D UMAG_00729 putative replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D UMAG_00920 putative DNA replication factor C subunit protein K10756 RFC3_5; replication factor C subunit 3/5
D UMAG_04623 putative replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D UMAG_10765 hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D UMAG_06131 hypothetical protein K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
C Other elongation factors
D UMAG_05403 putative proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D UMAG_05028 hypothetical protein K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D UMAG_01122 hypothetical protein K19783 HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]
D UMAG_05912 putative multifunctional nuclease RAD27 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D UMAG_03141 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D UMAG_11196 putative DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C DNA methylation enzymes
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
E UMAG_00963 hypothetical protein K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E UMAG_05892 hypothetical protein K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
C Telomerase complex (animals)
D UMAG_11198 hypothetical protein K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E UMAG_04573 putative H/ACA snoRNP pseudouridylase subunit GAR1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E UMAG_03340 putative nucleolar rRNA processing protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E UMAG_03354 putative nucleolar rRNA processing protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E UMAG_00685 putative pseudouridine synthase CBF5 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D UMAG_11198 hypothetical protein K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E UMAG_12244 hypothetical protein K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E UMAG_10381 putative small nuclear ribonucleoprotein SNRPD1 K11087 SNRPD1; small nuclear ribonucleoprotein D1
E UMAG_04781 putative small nuclear ribonucleoprotein chain D2 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E UMAG_11043 hypothetical protein K11088 SNRPD3; small nuclear ribonucleoprotein D3
E UMAG_10312 putative small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E UMAG_12130 putative Small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E UMAG_10805 putative snRNP G protein K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D UMAG_00216 putative DNA replication factor C subunit protein K10755 RFC2_4; replication factor C subunit 2/4
D UMAG_00729 putative replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D UMAG_00920 putative DNA replication factor C subunit protein K10756 RFC3_5; replication factor C subunit 3/5
D UMAG_04623 putative replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D UMAG_04704 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D UMAG_01085 putative DNA repair protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
C Other termination factors
D UMAG_15011 hypothetical protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D UMAG_02874 hypothetical protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D UMAG_10396 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D UMAG_04472 hypothetical protein K11135 PINX1; Pin2-interacting protein X1
D UMAG_02606 hypothetical protein K11137 TELO2; telomere length regulation protein
D UMAG_02718 hypothetical protein K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D UMAG_11746 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
D UMAG_00610 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
D UMAG_05335 hypothetical protein K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C UMAG_05101 DNA topoisomerase I K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C UMAG_03501 putative DNA topoisomerase II K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C UMAG_11929 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E UMAG_10765 hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E UMAG_10765 hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E UMAG_05028 hypothetical protein K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E UMAG_05912 putative multifunctional nuclease RAD27 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E UMAG_11196 putative DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 3, 2025