+D Protein KO
#
Membrane Trafficking - Aspergillus clavatus
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
D ACLA_007060 septin AspB K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D ACLA_040500 serine/threonine protein kinase, putative K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D ACLA_022180 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1, putative K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D ACLA_075440 phospholipase D Active site motif protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D ACLA_033640 phospholipase D1 (PLD1), putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D ACLA_007360 phospholipase PldA, putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D ACLA_034040 multicopy suppressor of stt4 mutation K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D ACLA_089970 serine/threonine kinase Ste20 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
D ACLA_006030 Ste20-like serine/threonine protein kinase, putative K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D ACLA_003020 Mst3-like protein kinase, putative K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D ACLA_001680 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D ACLA_024470 serine/threonine protein kinase Kin1, putative K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D ACLA_087350 calcium sensor (NCS-1), putative K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D ACLA_053530 Rab GTPase SrgA, putative K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D ACLA_049270 calmodulin K02183 CALM; calmodulin
D ACLA_034380 GDP/GTP exchange factor Sec2p, putative K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D ACLA_013730 Sec1 family superfamily K15292 STXBP1; syntaxin-binding protein 1
D ACLA_038960 SNARE-dependent exocytosis protein (Sro7), putative K08518 STXBP5; syntaxin-binding protein 5
D ACLA_012640 phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D ACLA_010700 GTPase activating protein (Gyp2), putative K19951 TBC1D8_9; TBC1 domain family member 8/9
D ACLA_058680 tetratricopeptide repeat protein K13342 PEX5; peroxin-5
D ACLA_098340 Rab geranylgeranyl transferase escort protein, putative K23460 CHM; Rab proteins geranylgeranyltransferase component A
D ACLA_049780 protein prenyltransferase alpha subunit repeat protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D ACLA_006160 Rab geranylgeranyltransferase, beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D ACLA_021750 WD repeat protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D ACLA_068600 Rho GTPase ModA, putative K04393 CDC42; cell division control protein 42
D ACLA_034260 Rho GTPase Rac, putative K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D ACLA_030390 Exocyst complex component Sec3, putative K19983 EXOC1; exocyst complex component 1
D ACLA_022680 Exocyst complex component Sec5, putative K17637 EXOC2; exocyst complex component 2
D ACLA_049690 Exocyst complex component Sec6, putative K06110 EXOC3; exocyst complex component 3
D ACLA_012480 Sec8 exocyst complex component specific domain protein K06111 EXOC4; exocyst complex component 4
D ACLA_042920 Exocyst complex component Sec10, putative K19984 EXOC5; exocyst complex component 5
D ACLA_095260 exocyst complex component Sec15, putative K19985 EXOC6; exocyst complex component 6
D ACLA_070860 Exocyst complex component Exo70, putative K07195 EXOC7; exocyst complex component 7
D ACLA_085030 Exocyst complex component Exo84, putative K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D ACLA_025190 26 proteasome complex subunit Sem1, putative K10881 SHFM1; 26 proteasome complex subunit DSS1
D ACLA_005910 tropomyosin, putative K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D ACLA_097970 chitin biosynthesis protein (Chs5), putative K19877 CHS5; chitin biosynthesis protein CHS5
D ACLA_040650 clathrin-coated vesiclec protein (Bud7), putative K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D ACLA_041600 vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D ACLA_001490 CRAL/TRIO domain protein K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D ACLA_066060 SNARE domain protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D ACLA_049260 SNARE complex subunit (Tlg2), putative K08489 STX16; syntaxin 16
C Stx-cisGolgi
D ACLA_035340 ER-Golgi SNARE complex subunit (Sed5), putative K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D ACLA_049880 vesicle transport v-snare protein, putative K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D ACLA_025020 Vesicle transport v-SNARE protein superfamily K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
C Sec20
D ACLA_036340 Sec20 domain protein K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
D ACLA_002250 SNARE domain protein K08499 TLG1; member of the syntaxin family of t-SNAREs
C STX8
D ACLA_074770 SNARE complex subunit (Syn8), putative K08501 STX8; syntaxin 8
D ACLA_092180 SNARE complex subunit (Vam7), putative K08502 VAM7; regulator of vacuolar morphogenesis
C STX10
C Bet1
D ACLA_082810 hypothetical protein K08504 BET1; blocked early in transport 1
D ACLA_027190 SNARE complex subunit (Bet1), putative K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D ACLA_073880 plasma membrane SNARE protein (Sec9), putative K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D ACLA_097510 SNARE protein Snc2, putative K08513 VAMP4; vesicle-associated membrane protein 4
D ACLA_084940 synaptobrevin-like protein Sybl1, putative K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D ACLA_048800 SNARE protein Ykt6, putative K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D ACLA_096480 protein transport protein sec22 K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D ACLA_038960 SNARE-dependent exocytosis protein (Sro7), putative K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D ACLA_013730 Sec1 family superfamily K15292 STXBP1; syntaxin-binding protein 1
D ACLA_041800 Golgi transport protein Sly1, putative K19998 SCFD1; sec1 family domain-containing protein 1
D ACLA_047300 hypothetical protein K26808 TXLN; taxilin
C Palmitoyltransferases
D ACLA_075390 DHHC zinc finger domain protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D ACLA_081730 DHHC zinc finger domain protein K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D ACLA_079670 palmitoyltransferase (SidR), putative K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D ACLA_040350 vesicular fusion ATPase, putative K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D ACLA_071690 vesicular-fusion protein sec17 K15296 NAPA; alpha-soluble NSF attachment protein
D ACLA_051940 vacuolar targeting protein Atg24, putative K17919 SNX4; sorting nexin-4
D ACLA_073450 autophagy protein Atg20, putative K21996 SNX41_42; sorting nexin-41/42
D ACLA_027940 Golgi phosphoprotein 3 (GPP34) domain containing protein K15620 GOLPH3; golgi phosphoprotein 3
D ACLA_076080 cell division control protein Cdc48 K13525 VCP; transitional endoplasmic reticulum ATPase
D ACLA_001560 Cdc48-dependent protein degradation adaptor protein (Shp1), putative K14012 NSFL1C; UBX domain-containing protein 1
D ACLA_029650 SAM domain protein K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D ACLA_047060 clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D ACLA_042880 dynamin-like GTPase Dnm1, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D ACLA_054080 AP-2 adaptor complex subunit alpha, putative K11824 AP2A; AP-2 complex subunit alpha
D ACLA_069370 AP-2 adaptor complex subunit beta, putative K11825 AP2B1; AP-2 complex subunit beta-1
D ACLA_012580 AP-2 adaptor complex subunit mu, putative K11826 AP2M1; AP-2 complex subunit mu-1
D ACLA_021470 AP-2 adaptor complex subunit sigma, putative K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D ACLA_021830 hypothetical protein K20042 FCHO; F-BAR domain only protein
D ACLA_085820 EH domain binding protein epsin 2 K12471 EPN; epsin
D ACLA_090850 Golgi to endosome transport protein (Ent3), putative K12471 EPN; epsin
D ACLA_031870 hypothetical protein K12472 EPS15; epidermal growth factor receptor substrate 15
D ACLA_090410 ENTH domain protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D ACLA_041720 BAR adaptor protein RVS167, putative K12562 AMPH; amphiphysin
D ACLA_057890 cytoskeleton assembly control protein Sla1, putative K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D ACLA_005570 DUF1720 domain protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D ACLA_022460 cytoskeletal adaptor protein SagA K20048 END3; actin cytoskeleton-regulatory complex protein END3
D ACLA_057260 Hsp70 chaperone (HscA), putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D ACLA_027170 molecular chaperone Hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D ACLA_034040 multicopy suppressor of stt4 mutation K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D ACLA_015590 hypothetical protein K20059 LDB19; arrestin-related trafficking adapter 1
D ACLA_013830 hypothetical protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D ACLA_023560 arrestin domain protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D ACLA_044550 hypothetical protein K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D ACLA_082820 carbon catabolite repression protein CreD, putative K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D ACLA_048930 pH response protein PalF K20063 RIM8; arrestin-related trafficking adapter 9
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D ACLA_012640 phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D ACLA_005350 SacI domain and endonuclease/exonuclease/phosphatase family protein K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D ACLA_028670 serine/threonine protein kinase, putative K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D ACLA_045470 protein kinase Scy1, putative K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D ACLA_026000 ubiquitin-protein ligase (Rsp5), putative K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D ACLA_034100 ANTH domain protein K20040 HIP1R; huntingtin-interacting protein 1-related protein
D ACLA_051820 calnexin K08054 CANX; calnexin
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D ACLA_042880 dynamin-like GTPase Dnm1, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D ACLA_014990 protein kinase c K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D ACLA_068600 Rho GTPase ModA, putative K04393 CDC42; cell division control protein 42
D ACLA_023910 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D ACLA_039950 ADP-ribosylation factor 6, putative K07941 ARF6; ADP-ribosylation factor 6
D ACLA_034260 Rho GTPase Rac, putative K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D ACLA_088680 Rho GTPase Rho1 K04513 RHOA; Ras homolog gene family, member A
D ACLA_042880 dynamin-like GTPase Dnm1, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D ACLA_059080 myosin I MyoA K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D ACLA_014270 RAS small monomeric GTPase RasA K07827 KRAS; GTPase KRas
D ACLA_079750 Ras small monomeric GTPase RasB K07827 KRAS; GTPase KRas
D ACLA_034260 Rho GTPase Rac, putative K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D ACLA_068600 Rho GTPase ModA, putative K04393 CDC42; cell division control protein 42
C Kinases
D ACLA_011860 phosphoinositide 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D ACLA_081620 1-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D ACLA_089970 serine/threonine kinase Ste20 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C Phospholipase C
D ACLA_022180 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1, putative K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D ACLA_051800 sorting nexin 3 K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D ACLA_041720 BAR adaptor protein RVS167, putative K12562 AMPH; amphiphysin
D ACLA_009220 BAR domain protein K20120 BIN3; bridging integrator 3
C F-BAR proteins
D ACLA_094510 actin polymerization protein Bzz1, putative K20121 FNBP1; formin-binding protein 1
D ACLA_021830 hypothetical protein K20042 FCHO; F-BAR domain only protein
D ACLA_034240 Rho GTPase activator (Rgd1), putative K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D ACLA_047400 RAB GTPase Ypt5, putative K07889 RAB5C; Ras-related protein Rab-5C
D ACLA_038630 RAB GTPase Vps21/Ypt51, putative K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D ACLA_051470 guanine nucleotide exchange factor Vps9, putative K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D ACLA_041600 vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D ACLA_012640 phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D ACLA_011860 phosphoinositide 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D ACLA_084850 protein kinase (VPS15), putative K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D ACLA_095680 vacuolar protein sorting-associated protein VpsB K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D ACLA_023910 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D ACLA_039950 ADP-ribosylation factor 6, putative K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D ACLA_082920 stromal membrane-associated protein K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D ACLA_005440 phosphatidylinositol 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D ACLA_041320 hypothetical protein K21842 EFR3; protein EFR3
D ACLA_009880 filamentation protein (Rhf1), putative K21845 YPP1; cargo-transport protein YPP1
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D ACLA_047400 RAB GTPase Ypt5, putative K07889 RAB5C; Ras-related protein Rab-5C
D ACLA_038630 RAB GTPase Vps21/Ypt51, putative K07889 RAB5C; Ras-related protein Rab-5C
D ACLA_015150 Rab small monomeric GTPase Rab7, putative K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D ACLA_038260 vacuolar sorting protein 35 K18468 VPS35; vacuolar protein sorting-associated protein 35
D ACLA_026020 vacuolar protein sorting 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
D ACLA_051070 Vacuolar protein sorting-associated protein 26, putative K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D ACLA_027120 microtubule binding protein HOOK3, putative K16536 HOOK3; protein HOOK3
C Rab associated proteins
D ACLA_072120 RING finger domain protein, putative K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D ACLA_011860 phosphoinositide 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D ACLA_003100 proteasome component Pre6, putative K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D ACLA_091970 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D ACLA_096670 GTPase activating protein (Gyp7), putative K20168 TBC1D15; TBC1 domain family member 15
D ACLA_098340 Rab geranylgeranyl transferase escort protein, putative K23460 CHM; Rab proteins geranylgeranyltransferase component A
D ACLA_049780 protein prenyltransferase alpha subunit repeat protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D ACLA_006160 Rab geranylgeranyltransferase, beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D ACLA_084890 TBC domain protein, putative K20176 SGSM3; small G protein signaling modulator 3
D ACLA_027940 Golgi phosphoprotein 3 (GPP34) domain containing protein K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
D ACLA_082380 ADP-ribosylation factor family protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D ACLA_037780 acetyltransferase, GNAT family, putative K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D ACLA_081140 amino-acid N-acetyltransferase subunit Mak10, putative K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D ACLA_090550 LSM domain protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D ACLA_089930 vacuolar sorting-associated protein (Vps27), putative K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D ACLA_089980 SH3 domain protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D ACLA_041850 endosomal sorting complex protein TSG101, putative K12183 TSG101; ESCRT-I complex subunit TSG101
D ACLA_019240 vacuolar protein sorting-associated protein Vps28, putative K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D ACLA_054570 ELL complex subunit Eap30, putative K12188 SNF8; ESCRT-II complex subunit VPS22
D ACLA_051290 DUF852 domain protein K12189 VPS25; ESCRT-II complex subunit VPS25
D ACLA_054290 vacuolar protein sorting protein (Vps36), putative K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D ACLA_060690 SNF7 family protein (Fti1/Did2), putative K12197 CHMP1; charged multivesicular body protein 1
D ACLA_016390 SNF7 family protein K12191 CHMP2A; charged multivesicular body protein 2A
D ACLA_016910 SNF7 family protein K12193 VPS24; charged multivesicular body protein 3
D ACLA_028170 SNF7 family protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D ACLA_050120 SNF7 family protein (Cta1), putative K12198 CHMP5; charged multivesicular body protein 5
D ACLA_026250 SNF7 family protein K12195 CHMP6; charged multivesicular body protein 6
D ACLA_075600 SNF7 family protein K15053 CHMP7; charged multivesicular body protein 7
D ACLA_037280 vacuolar sorting ATPase Vps4, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D ACLA_031150 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D ACLA_045710 pH signal transduction protein PalA, putative K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D ACLA_021150 TGF beta receptor associated protein 1, putative K20177 VPS3; vacuolar protein sorting-associated protein 3
D ACLA_029370 Golgi complex component (Vps8), putative K20178 VPS8; vacuolar protein sorting-associated protein 8
D ACLA_084120 vacuolar protein sorting protein (VPS11), putative K20179 VPS11; vacuolar protein sorting-associated protein 11
D ACLA_016600 vacuolar protein sorting vps16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D ACLA_009780 vacuolar protein sorting protein DigA K20181 VPS18; vacuolar protein sorting-associated protein 18
D ACLA_073890 vacuolar sorting protein, putative K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D ACLA_084120 vacuolar protein sorting protein (VPS11), putative K20179 VPS11; vacuolar protein sorting-associated protein 11
D ACLA_016600 vacuolar protein sorting vps16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D ACLA_009780 vacuolar protein sorting protein DigA K20181 VPS18; vacuolar protein sorting-associated protein 18
D ACLA_073890 vacuolar sorting protein, putative K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D ACLA_007480 vacuolar morphogenesis protein AvaB, putative K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D ACLA_039110 vacuolar assembly protein, putative K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D ACLA_021750 WD repeat protein K24155 DMXL; rabconnectin-3a
C RAVE complex
D ACLA_021750 WD repeat protein K24155 DMXL; rabconnectin-3a
D ACLA_009360 sulfur metabolism regulator SkpA, putative K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D ACLA_005320 AP-3 complex subunit delta, putative K12396 AP3D; AP-3 complex subunit delta
D ACLA_014440 AP-3 adaptor complex subunit beta, putative K12397 AP3B; AP-3 complex subunit beta
D ACLA_052460 AP-3 adaptor complex subunit mu, putative K12398 AP3M; AP-3 complex subunit mu
D ACLA_086270 clathrin adaptor complex small subunit, putative K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
D ACLA_040360 hypothetical protein K22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D ACLA_089650 SAND protein protein K20195 MON1; vacuolar fusion protein MON1
D ACLA_089940 ubiquitin C-terminal hydrolase, putative K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D ACLA_036710 endosome-associated ubiquitin isopeptidase (AmsH), putative K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D ACLA_002900 vacuolar dynamin-like GTPase VpsA, putative K23481 VPS1; vacuolar protein sorting-associated protein 1
D ACLA_011350 Beige/BEACH domain protein K24781 BPH1; beige protein homolog 1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D ACLA_032240 Ras GTPase Rab11, putative K07904 RAB11A; Ras-related protein Rab-11A
C Rab4 associated proteins
D ACLA_041600 vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D ACLA_051940 vacuolar targeting protein Atg24, putative K17919 SNX4; sorting nexin-4
D ACLA_012020 dynein light intermediate chain K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D ACLA_015340 WD repeat protein K20241 WDR44; WD repeat-containing protein 44
D ACLA_045400 nuclear pore complex subunit (SEC13), putative K14004 SEC13; protein transport protein SEC13
D ACLA_095260 exocyst complex component Sec15, putative K19985 EXOC6; exocyst complex component 6
D ACLA_027940 Golgi phosphoprotein 3 (GPP34) domain containing protein K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D ACLA_012640 phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D ACLA_051470 guanine nucleotide exchange factor Vps9, putative K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D ACLA_025130 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D ACLA_036800 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D ACLA_030550 Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D ACLA_029560 GARP complex subunit Vps53, putative K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D ACLA_082080 F-actin capping protein alpha subunit, putative K10364 CAPZA; F-actin-capping protein subunit alpha
D ACLA_031550 f-actin capping protein beta subunit K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D ACLA_026020 vacuolar protein sorting 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D ACLA_074510 rab6 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D ACLA_027940 Golgi phosphoprotein 3 (GPP34) domain containing protein K15620 GOLPH3; golgi phosphoprotein 3
D ACLA_010700 GTPase activating protein (Gyp2), putative K19951 TBC1D8_9; TBC1 domain family member 8/9
D ACLA_024830 hypothetical protein K20286 TMF1; TATA element modulatory factor
D ACLA_072260 dynactin, putative K04648 DCTN1; dynactin 1
D ACLA_012640 phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D ACLA_050640 vacuolar protein sorting-associated protein vps13 K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D ACLA_023910 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D ACLA_069950 ADP-ribosylation factor, putative K07942 ARL1; ADP-ribosylation factor-like protein 1
D ACLA_018540 ADP-ribosylation factor family protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D ACLA_010390 zinc finger protein gcs1 K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D ACLA_068910 ARF GTPase activator (Glo3), putative K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D ACLA_082920 stromal membrane-associated protein K12486 SMAP; stromal membrane-associated protein
D ACLA_005500 ARF GTPase activator (Csx2), putative K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
D ACLA_007410 guanyl-nucleotide exchange factor (Sec7), putative K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D ACLA_014930 Sec7 domain protein K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D ACLA_096400 hypothetical protein K20288 COG1; conserved oligomeric Golgi complex subunit 1
D ACLA_001590 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D ACLA_039010 Golgi complex component Cog3, putative K20290 COG3; conserved oligomeric Golgi complex subunit 3
D ACLA_068440 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D ACLA_085730 Golgi transport complex subunit Cog6, putative K20293 COG6; conserved oligomeric Golgi complex subunit 6
D ACLA_037900 hypothetical protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D ACLA_036800 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D ACLA_030550 Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D ACLA_029560 GARP complex subunit Vps53, putative K20299 VPS53; vacuolar protein sorting-associated protein 53
D ACLA_002650 GARP complex component (Vps54), putative K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D ACLA_009250 TRAPP complex subunit (Bet5), putative K20300 TRAPPC1; trafficking protein particle complex subunit 1
D ACLA_080570 trafficking protein particle complex subunit 2/Sedlin, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D ACLA_045120 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D ACLA_065260 BET3 family protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D ACLA_072390 sybindin-like family protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D ACLA_015780 BET3 family protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D ACLA_095310 BET3 family protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D ACLA_075590 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D ACLA_095700 hypercellular protein HypA K20306 TRAPPC9; trafficking protein particle complex subunit 9
D ACLA_022960 hypothetical protein K20307 TRAPPC10; trafficking protein particle complex subunit 10
D ACLA_026400 hypothetical protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D ACLA_038480 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
D ACLA_045820 DUF974 domain protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D ACLA_028570 AP-1 adaptor complex subunit gamma, putative K12391 AP1G1; AP-1 complex subunit gamma-1
D ACLA_036940 AP-1 adaptor complex subunit beta, putative K12392 AP1B1; AP-1 complex subunit beta-1
D ACLA_010880 AP-1 adaptor complex subunit mu, putative K12393 AP1M; AP-1 complex subunit mu
D ACLA_093370 clathrin coat assembly protein ap19 K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D ACLA_005320 AP-3 complex subunit delta, putative K12396 AP3D; AP-3 complex subunit delta
D ACLA_014440 AP-3 adaptor complex subunit beta, putative K12397 AP3B; AP-3 complex subunit beta
D ACLA_052460 AP-3 adaptor complex subunit mu, putative K12398 AP3M; AP-3 complex subunit mu
D ACLA_086270 clathrin adaptor complex small subunit, putative K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
D ACLA_027880 VHS domain protein K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D ACLA_096420 HEAT repeat protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D ACLA_075440 phospholipase D Active site motif protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D ACLA_033640 phospholipase D1 (PLD1), putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D ACLA_007360 phospholipase PldA, putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D ACLA_005440 phosphatidylinositol 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D ACLA_034040 multicopy suppressor of stt4 mutation K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D ACLA_081620 1-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D ACLA_091260 bZIP transcription factor, putative K20316 SCOC; short coiled-coil protein
D ACLA_037590 hypothetical protein K20318 SYS1; protein SYS1
D ACLA_035030 UPF0016 domain protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D ACLA_092580 hypothetical protein K23542 TMEM199; TMEM199 family protein
D ACLA_034450 hypothetical protein K23543 CCDC115; coiled-coil domain-containing protein 115
D ACLA_072210 membrane protein TMS1, putative K23544 SERINC1; serine incorporator 1
D ACLA_076120 sorting nexin Mvp1 K17922 SNX8; sorting nexin-8
D ACLA_051080 hypothetical protein K26678 MON2; protein MON2
D ACLA_089640 Dopey, N-terminal domain protein K26680 DOP1; protein dopey
D ACLA_014330 COPI-coated vesicle protein, putative K26750 TVP15; golgi apparatus membrane protein TVP15
D ACLA_038490 clathrin-coated vesicle protein, putative K26751 TVP18; golgi apparatus membrane protein TVP18
D ACLA_052040 clathrin-coated vesicle protein, putative K26752 TVP23; golgi apparatus membrane protein TVP23
D ACLA_052010 hypothetical protein K26753 TVP38; golgi apparatus membrane protein TVP38
D ACLA_002900 vacuolar dynamin-like GTPase VpsA, putative K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D ACLA_029700 small monomeric GTPase SarA, putative K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D ACLA_045400 nuclear pore complex subunit (SEC13), putative K14004 SEC13; protein transport protein SEC13
D ACLA_071790 protein transport protein (SEC31), putative K14005 SEC31; protein transport protein SEC31
D ACLA_031210 protein transport protein Sec23, putative K14006 SEC23; protein transport protein SEC23
D ACLA_086070 protein transport protein Sec24, putative K14007 SEC24; protein transport protein SEC24
D ACLA_037470 Sec23/Sec24 family protein K14007 SEC24; protein transport protein SEC24
D ACLA_096630 hypothetical protein K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D ACLA_009250 TRAPP complex subunit (Bet5), putative K20300 TRAPPC1; trafficking protein particle complex subunit 1
D ACLA_080570 trafficking protein particle complex subunit 2/Sedlin, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D ACLA_045120 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D ACLA_065260 BET3 family protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D ACLA_072390 sybindin-like family protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D ACLA_015780 BET3 family protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D ACLA_095310 BET3 family protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D ACLA_046710 endosomal cargo receptor (Erp5), putative K20346 TMED4_9_11; p24 family protein alpha
D ACLA_024180 endosomal cargo receptor (P24), putative K20347 TMED2; p24 family protein beta-1
D ACLA_052170 endosomal cargo receptor (Erv25), putative K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D ACLA_068160 protein disulfide isomerase Pdi1, putative K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D ACLA_029330 disulfide isomerase, putative K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D ACLA_015280 disulfide isomerase (TigA), putative K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D ACLA_000830 rab15, 13, 10, 1, 35, 5, and K07874 RAB1A; Ras-related protein Rab-1A
D ACLA_026910 secretion related GTPase SrgD K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D ACLA_088400 Prenylated Rab acceptor 1, putative K20359 RABAC1; PRA1 family protein 1
D ACLA_030600 TBC domain protein, putative K20372 TBC1D20; TBC1 domain family member 20
D ACLA_068250 TBC domain putative K20360 TBC1D22; TBC1 domain family member 2
D ACLA_096770 ER to Golgi transport protein Yif1 K20362 YIF1; protein transport protein YIF1
D ACLA_051870 hypothetical protein K22939 IER3IP1; immediate early response 3-interacting protein 1
D ACLA_021720 intracellular protein transport protein (UsoA), putative K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D ACLA_075710 lectin family integral membrane protein, putative K10080 LMAN1; lectin, mannose-binding 1
D ACLA_071060 lectin family integral membrane protein, putative K10082 LMAN2; lectin, mannose-binding 2
D ACLA_085610 class I alpha-mannosidase 1A K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D ACLA_049290 class I alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D ACLA_020870 mannosidase MsdS K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D ACLA_088570 mannosyl-oligosaccharide alpha-1,2-mannosidase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D ACLA_093400 COPII-coated vesicle protein (Erv41), putative K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D ACLA_029530 COPII-coated vesicle membrane protein Erv46, putative K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D ACLA_081430 endosomal cargo receptor (Erv14), putative K20368 CNIH; protein cornichon
D ACLA_023880 COPII-coated vesicle protein SurF4/Erv29, putative K20369 ERV29; ER-derived vesicles protein
D ACLA_090010 ER Hsp70 chaperone BiP, putative K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D ACLA_036820 Coatomer subunit alpha, putative K05236 COPA; coatomer subunit alpha
D ACLA_024540 Coatomer subunit beta, putative K17301 COPB1; coatomer subunit beta
D ACLA_069610 COPI vesicle coat beta' subunit, putative K17302 COPB2; coatomer subunit beta'
D ACLA_092240 Coatomer subunit gamma, putative K17267 COPG; coatomer subunit gamma
D ACLA_019500 Coatomer subunit delta, putative K20471 COPD; coatomer subunit delta
D ACLA_022170 Coatomer subunit epsilon, putative K17268 COPE; coatomer subunit epsilon
D ACLA_080990 Coatomer subunit zeta, putative K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D ACLA_039050 RINT-1 family protein K20474 RINT1; RAD50-interacting protein 1
D ACLA_046940 hypothetical protein K11578 ZW10; protein transport protein DSL1/ZW10
D ACLA_028740 hypothetical protein K20475 SEC39; protein transport protein SEC39
C Golgi to ER traffic proteins (GET)
D ACLA_045650 CHD5 domain protein K22384 GET1; tail-anchored protein insertion receptor
D ACLA_050190 hypothetical protein K22386 GET2; GET complex subunit GET2
D ACLA_039240 arsenite translocating ATPase ArsA, putative K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D ACLA_095500 DUF410 domain protein K23387 GET4; golgi to ER traffic protein 4
D ACLA_003550 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
C Rab GTPases
D ACLA_074510 rab6 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D ACLA_025680 DUF1339 domain protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D ACLA_071230 intracellular protein transport protein (Sat1), putative K20477 RGP1; RAB6A-GEF complex partner protein 2
D ACLA_000720 er lumen protein retaining receptor K10949 KDELR; ER lumen protein retaining receptor
D ACLA_041600 vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D ACLA_068250 TBC domain putative K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D ACLA_065060 oxysterol binding protein (Osh1), putative K20456 OSBP; oxysterol-binding protein 1
D ACLA_033850 oxysterol binding protein K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
D ACLA_090720 oxysterol binding protein (Osh7), putative K22285 OSBPL8; oxysterol-binding protein-related protein 8
D ACLA_033530 oxysterol-binding protein, putative K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
D ACLA_039630 oxysterol binding protein (Osh5), putative K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D ACLA_030590 Yip1 domain family K22940 YIPF1_2; protein YIPF1/2
D ACLA_053720 Golgi membrane protein, putative K20363 YIPF5_7; protein YIPF5/7
D ACLA_069790 nuclear protein export protein Yrb2, putative K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D ACLA_011300 DUF1620 domain protein K23562 EMC1; ER membrane protein complex subunit 1
D ACLA_005330 F-box domain protein K23563 EMC2; ER membrane protein complex subunit 2
D ACLA_058780 DUF850 domain protein K23564 EMC3; ER membrane protein complex subunit 3
D ACLA_069380 ER membrane DUF1077 domain protein, putative K23565 EMC4; ER membrane protein complex subunit 4
D ACLA_024350 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D ACLA_029640 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
D ACLA_000870 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
C SEC61 complex
D ACLA_012390 protein transport protein Sec61 alpha subunit, putative K10956 SEC61A; protein transport protein SEC61 subunit alpha
D ACLA_029760 translocon protein Sec61beta, putative K09481 SEC61B; protein transport protein SEC61 subunit beta
D ACLA_034860 protein translocase, putative K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D ACLA_049170 DUF1682 domain protein K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D ACLA_007230 GPI maturation protein (Bst1), putative K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D ACLA_028260 Mn2+ homeostasis protein (Per1), putative K23553 PGAP3; post-GPI attachment to proteins factor 3
D ACLA_072930 manganese ion homeostasis (Fr), putative K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D ACLA_041800 Golgi transport protein Sly1, putative K19998 SCFD1; sec1 family domain-containing protein 1
D ACLA_007070 hypothetical protein K20724 TMEM33; transmembrane protein 33
D ACLA_070440 hypothetical protein K21848 ARV1; lipid intermediate transporter
D ACLA_070810 beta-1,6 glucan synthetase (Kre6), putative K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D ACLA_027940 Golgi phosphoprotein 3 (GPP34) domain containing protein K15620 GOLPH3; golgi phosphoprotein 3
D ACLA_055990 hypothetical protein K23292 LNPK; endoplasmic reticulum junction formation protein lunapark
D ACLA_047000 INSIG domain protein K26681 INSIG; insulin-induced protein
D ACLA_055580 hypothetical protein K26683 GOLT1; vesicle transport protein GOT1
D ACLA_023280 GTP-binding protein Sey1, putative K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D ACLA_089890 autophagy protein Atg13, putative K08331 ATG13; autophagy-related protein 13
D ACLA_009620 DUF1649 domain protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D ACLA_048410 serine/threonine protein kinase (Pdd7p), putative K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D ACLA_089890 autophagy protein Atg13, putative K08331 ATG13; autophagy-related protein 13
D ACLA_073510 kinase activator (Atg17), putative K08329 ATG17; autophagy-related protein 17
C PI3K complex
D ACLA_011860 phosphoinositide 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D ACLA_084850 protein kinase (VPS15), putative K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D ACLA_058610 autophagy protein Apg6, putative K08334 BECN; beclin
C ATG9 transmembrane protein
D ACLA_085600 autophagy protein Apg9, putative K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D ACLA_014730 protein-vacuolar targeting protein Atg18, putative K17908 WIPI1_2; autophagy-related protein 18
D ACLA_086450 autophagy regulatory protein Atg2, putative K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D ACLA_083230 autophagy protein Apg12, putative K08336 ATG12; ubiquitin-like protein ATG12
D ACLA_068060 autophagy ubiquitin-activating enzyme ApgG, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D ACLA_088830 autophagy protein Apg5, putative K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D ACLA_027140 autophagic death protein Aut7/IDI-7, putative K08341 GABARAP; GABA(A) receptor-associated protein
D ACLA_033350 peptidase family C54 protein K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D ACLA_068060 autophagy ubiquitin-activating enzyme ApgG, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D ACLA_012340 autophagocytosis protein Aut1, putative K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D ACLA_001190 vacuolar aspartyl aminopeptidase Lap4, putative K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D ACLA_036160 alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D ACLA_036260 aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D ACLA_039480 Taz1-interacting factor 1 (TAF1), putative K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D ACLA_073450 autophagy protein Atg20, putative K21996 SNX41_42; sorting nexin-41/42
D ACLA_051940 vacuolar targeting protein Atg24, putative K17919 SNX4; sorting nexin-4
D ACLA_069880 autophagy related lipase Atg15, putative K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D ACLA_020170 autophagy protein Atg27, putative K21141 ATG27; autophagy-related protein 27
D ACLA_016530 vacuolar armadillo repeat protein Vac8, putative K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D ACLA_039480 Taz1-interacting factor 1 (TAF1), putative K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D ACLA_016380 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D ACLA_033790 ZZ type zinc finger domain protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other mitophagy associated proteins
D ACLA_098220 glucokinase GlkA, putative K00844 HK; hexokinase [EC:2.7.1.1]
D ACLA_096650 hexokinase, putative K00844 HK; hexokinase [EC:2.7.1.1]
D ACLA_005730 hexokinase, putative K00844 HK; hexokinase [EC:2.7.1.1]
D ACLA_068420 hexokinase Kxk, putative K00844 HK; hexokinase [EC:2.7.1.1]
D ACLA_091220 mitochondrial ATPase inhibitor, putative K22255 ATPIF1; ATPase inhibitor, mitochondrial
D ACLA_095360 TOM complex component Tom7, putative K17771 TOM7; mitochondrial import receptor subunit TOM7
D ACLA_010740 hypothetical protein K19717 ATG33; autophagy-related protein 33
B Pexophagy
C Selective cargos
D ACLA_009610 peroxisomal membrane protein (Pex3), putative K13336 PEX3; peroxin-3
D ACLA_038050 peroxisomal membrane anchor protein (Pex14), putative K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
D ACLA_033790 ZZ type zinc finger domain protein K17987 NBR1; next to BRCA1 gene 1 protein
D ACLA_069180 peroxisome biosynthesis protein (PAS1/Peroxin-1), putative K13338 PEX1; peroxin-1
D ACLA_035930 peroxisome assembly factor-2 (peroxisomal-type atpase 1) K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
D ACLA_033790 ZZ type zinc finger domain protein K17987 NBR1; next to BRCA1 gene 1 protein
C Scaffold proteins
C Other aggrephagy associated proteins
D ACLA_076080 cell division control protein Cdc48 K13525 VCP; transitional endoplasmic reticulum ATPase
D ACLA_003280 histone deacetylase hda1 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D ACLA_070010 U-box domain protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
D ACLA_033790 ZZ type zinc finger domain protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D ACLA_030240 aspartate aminotransferase, putative K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D ACLA_068740 aspartate transaminase, putative K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D ACLA_097980 aspartate transaminase, putative K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D ACLA_043170 glyceraldehyde-3-phosphate dehydrogenase, putative K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACLA_064170 glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACLA_004210 glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACLA_003290 glyceraldehyde 3-phosphate dehydrogenase GpdA K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACLA_081610 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D ACLA_086720 ubiquitin-like protein DskB, putative K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D ACLA_057260 Hsp70 chaperone (HscA), putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D ACLA_027170 molecular chaperone Hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D ACLA_000990 molecular chaperone Mod-E/Hsp90 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D ACLA_028450 translation elongation factor EF-1 alpha subunit, putative K03231 EEF1A; elongation factor 1-alpha
D ACLA_086840 carboxypeptidase CpyA/Prc1, putative K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
D ACLA_098670 carboxypeptidase Y, putative K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
D ACLA_040070 carboxypeptidase Y, putative K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D ACLA_016530 vacuolar armadillo repeat protein Vac8, putative K08332 VAC8; vacuolar protein 8
C Midbophagy
D ACLA_033790 ZZ type zinc finger domain protein K17987 NBR1; next to BRCA1 gene 1 protein
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D ACLA_016380 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D ACLA_069300 TOR pathway phosphatidylinositol 3-kinase TorA, putative K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D ACLA_025940 protein transport protein (LST8), putative K08266 MLST8; target of rapamycin complex subunit LST8
D ACLA_092290 meiotic regulator-interacting protein, putative K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D ACLA_069300 TOR pathway phosphatidylinositol 3-kinase TorA, putative K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D ACLA_025940 protein transport protein (LST8), putative K08266 MLST8; target of rapamycin complex subunit LST8
D ACLA_071090 stress activated MAP kinase interacting protein, putative K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D ACLA_069480 cytosolic regulator Pianissimo, putative K08267 RICTOR; rapamycin-insensitive companion of mTOR
C SEACIT/GATOR1 complex
D ACLA_089310 Dishevelled, Egl-10, and Pleckstrin domain protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D ACLA_030080 nitrogen permease regulator Npr2, putative K20405 NPRL2; nitrogen permease regulator 2
D ACLA_025740 UPF0171 domain protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D ACLA_091760 WD repeat protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D ACLA_098060 WD repeat protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D ACLA_091930 hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D ACLA_070200 nuclear pore protein (SEH1), putative K14299 SEH1; nucleoporin SEH1
D ACLA_045400 nuclear pore complex subunit (SEC13), putative K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D ACLA_000830 rab15, 13, 10, 1, 35, 5, and K07874 RAB1A; Ras-related protein Rab-1A
D ACLA_053530 Rab GTPase SrgA, putative K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D ACLA_084560 protein phosphatase 2a K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D ACLA_014830 TOR signalling pathway regulator (TapA), putative K17606 IGBP1; immunoglobulin-binding protein 1
D ACLA_016300 UV radiation resistance protein (UVRAG), putative K21249 UVRAG; UV radiation resistance-associated gene protein
D ACLA_074310 MFS transporter family protein, putative K06902 UMF1; MFS transporter, UMF1 family
D ACLA_068150 autophagy protein Atg22, putative K06902 UMF1; MFS transporter, UMF1 family
D ACLA_047130 amino acid transporter, putative K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D ACLA_094660 amino acid transporter, putative K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D ACLA_012000 phosphatidylinositol 3,5-bisphosphate-binding protein, putative K22991 WDR45; WD repeat-containing protein 45
D ACLA_036390 hypothetical protein K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21
D ACLA_066160 UPF0183 domain protein K27411 PHAF1; phagosome assembly factor 1
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
D ACLA_086610 NADPH oxidase (NoxA), putative K08008 NOX1; NADPH oxidase 1
C Nox associated proteins
D ACLA_034260 Rho GTPase Rac, putative K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D ACLA_059080 myosin I MyoA K10356 MYO1; myosin I
D ACLA_008850 class V myosin (Myo4), putative K10357 MYO5; myosin V
C Arp2/3 complex
D ACLA_088280 actin-related protein 2/3 complex subunit 1A, putative K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D ACLA_031720 ARP2/3 complex 34 kDa subunit, putative K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D ACLA_003470 ARP2/3 complex subunit Arc18, putative K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D ACLA_098100 ARP2/3 complex 20 kDa subunit (p20-ARC), putative K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D ACLA_038590 Arp2/3 complex subunit Arc16, putative K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D ACLA_022100 Arp2/3 complex subunit (Arp2), putative K17260 ACTR2; actin-related protein 2
D ACLA_014630 Arp2/3 complex subunit (Arp3), putative K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D ACLA_097920 actin associated protein Wsp1, putative K23612 WASL; neural Wiskott-Aldrich syndrome protein
D ACLA_042870 actin binding protein, putative K20520 DBNL; drebrin-like protein
D ACLA_005570 DUF1720 domain protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D ACLA_041720 BAR adaptor protein RVS167, putative K12562 AMPH; amphiphysin
D ACLA_057890 cytoskeleton assembly control protein Sla1, putative K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D ACLA_069350 SH3 domain protein K20521 BBC1; myosin tail region-interacting protein MTI1
D ACLA_036600 SH3 domain protein K20522 LSB1_2; LAS seventeen-binding protein 1/2
D ACLA_082790 DUF500 and SH3 domain protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D ACLA_083320 VHS domain protein K20524 LSB5; LAS seventeen-binding protein 5
D ACLA_072180 phosphatidylinositol 4-kinase type II subunit alpha, putative K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D ACLA_055570 profilin Pfy1, putative K05759 PFN; profilin
D ACLA_013580 cofilin K05765 CFL; cofilin
D ACLA_022710 adenylyl cyclase-associated protein (cap) K17261 CAP1_2; adenylyl cyclase-associated protein
D ACLA_087330 kinesin heavy chain subunit K10396 KIF5; kinesin family member 5
D ACLA_052220 transgelin, putative K20526 TAGLN; transgelin
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
C Lipid droplets
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D ACLA_034240 Rho GTPase activator (Rgd1), putative K20643 RGD1; Rho GTPase-activating protein RGD1
D ACLA_088180 RhoGAP domain protein K08773 RALBP1; RalA-binding protein 1
C Rho guanine nucleotide exchange factors (GEFs)
D ACLA_006290 Rho guanyl nucleotide exchange factor, putative K20705 DNMBP; dynamin-binding protein
D ACLA_030380 SH3 and Ded_cyto domain protein, putative K05727 DOCK3; dedicator of cytokinesis protein 3
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 15, 2024