+F Repair protein KO
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DNA Repair and Recombination Proteins - Actinobacillus delphinicola
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D NCTC12871_00642 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E NCTC12871_00201 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E NCTC12871_00525 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E NCTC12871_00226 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D NCTC12871_00481 mutT; mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC12871_00579 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D NCTC12871_00642 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E NCTC12871_00201 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E NCTC12871_00525 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E NCTC12871_00589 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E NCTC12871_00226 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E NCTC12871_01177 xthA; exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E NCTC12871_00562 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E NCTC12871_00719 ligA_1; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E NCTC12871_01069 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E NCTC12871_00512 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E NCTC12871_01636 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E NCTC12871_01368 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E NCTC12871_00197 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E NCTC12871_01069 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E NCTC12871_00719 ligA_1; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F NCTC12871_00782 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F NCTC12871_00783 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F NCTC12871_00993 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F NCTC12871_01114 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F NCTC12871_00353 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E NCTC12871_00961 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E NCTC12871_00069 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E NCTC12871_00472 mutH; DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E NCTC12871_01578 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E NCTC12871_01141 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E NCTC12871_00219 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E NCTC12871_00577 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E NCTC12871_01027 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E NCTC12871_00406 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E NCTC12871_01044 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E NCTC12871_00649 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E NCTC12871_01245 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NCTC12871_00098 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E NCTC12871_00260 holD; DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
D DNA ligase
E NCTC12871_00719 ligA_1; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E NCTC12871_00197 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E NCTC12871_00513 ssb_1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E NCTC12871_00825 ssb_2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E NCTC12871_01133 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E NCTC12871_01656 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E NCTC12871_00613 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E NCTC12871_01657 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E NCTC12871_00678 recA; recombinase A K03553 recA; recombination protein RecA
E NCTC12871_00625 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E NCTC12871_00624 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E NCTC12871_00626 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E NCTC12871_00957 priA; primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E NCTC12871_01103 priB; primosomal replication protein N K02686 priB; primosomal replication protein N
E NCTC12871_01588 Primosomal replication protein N'' K04067 priC; primosomal replication protein N''
E NCTC12871_01578 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E NCTC12871_00678 recA; recombinase A K03553 recA; recombination protein RecA
E NCTC12871_00237 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E NCTC12871_01026 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
E NCTC12871_01116 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E NCTC12871_00562 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E NCTC12871_00576 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E NCTC12871_01646 recR; recombination protein RecR K06187 recR; recombination protein RecR
E NCTC12871_01494 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E NCTC12871_01565 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E NCTC12871_00625 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E NCTC12871_00624 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E NCTC12871_00626 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E NCTC12871_00160 CRISPR-associated Cas1 family protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F NCTC12871_00426 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F NCTC12871_00590 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F NCTC12871_00016 topA_1; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F NCTC12871_00102 hupA; DNA-binding protein HU K05787 hupA; DNA-binding protein HU-alpha
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F NCTC12871_00562 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F NCTC12871_00576 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F NCTC12871_01646 recR; recombination protein RecR K06187 recR; recombination protein RecR
F NCTC12871_00719 ligA_1; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F NCTC12871_00354 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F NCTC12871_01650 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F NCTC12871_00339 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F NCTC12871_01578 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F NCTC12871_00920 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F NCTC12871_00512 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F NCTC12871_01636 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F NCTC12871_01490 stpA; histone family protein nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D NCTC12871_01580 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D NCTC12871_00678 recA; recombinase A K03553 recA; recombination protein RecA
D NCTC12871_01101 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D NCTC12871_01494 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D NCTC12871_00513 ssb_1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC12871_00825 ssb_2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC12871_00679 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D NCTC12871_00364 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D NCTC12871_01502 dinG; helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D NCTC12871_00481 mutT; mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC12871_00579 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D NCTC12871_00785 nrdA; ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D NCTC12871_00791 nrdB; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024