+E Replication protein KO
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DNA Replication Proteins - Alteromonas sp. RKMC-009
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D DS731_12025 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
D DS731_21460 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D DS731_14455 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D DS731_12320 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
D DS731_11395 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
D DS731_00005 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D DS731_02425 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D DS731_12615 hypothetical protein K02315 dnaC; DNA replication protein DnaC
D DS731_21580 AAA family ATPase K02315 dnaC; DNA replication protein DnaC
D DS731_03945 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D DS731_07455 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D DS731_19595 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E DS731_06180 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E DS731_00010 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E DS731_16315 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E DS731_09735 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E DS731_11865 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E DS731_12020 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DS731_20690 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DS731_17980 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DS731_13970 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E DS731_12025 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E DS731_06175 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E DS731_00075 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E DS731_10320 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E DS731_12025 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E DS731_06175 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
D DS731_21690 hypothetical protein K10748 tus; DNA replication terminus site-binding protein
C DNA methylation enzymes
D DS731_18825 Dam family site-specific DNA-(adenine-N6)-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C Prevention of re-replication factors
D DS731_13110 seqA; replication initiation negative regulator SeqA K03645 seqA; negative modulator of initiation of replication
D DS731_11520 hda; DnaA regulatory inactivator Hda K10763 hda; DnaA-homolog protein
B DNA Topoisomerases
C DS731_11420 gyrA; DNA topoisomerase (ATP-hydrolyzing) subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C DS731_00020 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C DS731_18895 parC; DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C DS731_03570 parE; DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C DS731_11960 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C DS731_10250 DNA topoisomerase IB K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022