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#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Mitochondrial Biogenesis - Buchnera aphidicola JF99 (Acyrthosiphon pisum)</h2>
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A<b>Mitochondrial DNA transcription, translation, and replication factors</b>
B  Mitochondrial DNA-encoded proteins
C    Mitochondrial respiratory chain complex I
C    Mitochondrial respiratory chain complex III
C    Cytochrome c oxidase
C    F-type ATPase
B  Mitochondrial transcription and translation factors
C    Mitochondrial RNA polymerase
C    Mitochondrial transcription factors
C    Mitochondrial translation factors
D      CWS_01985 infB; translation initiation factor IF-2	K02519 infB; translation initiation factor IF-2 
D      CWS_00640 infC; translation initiation factor IF-3	K02520 infC; translation initiation factor IF-3 
D      CWS_01225 tsf; elongation factor Ts	K02357 tsf; elongation factor Ts 
D      CWS_02720 elongation factor Tu	K02358 tuf; elongation factor Tu 
D      CWS_02725 elongation factor G	K02355 fusA; elongation factor G 
C    RNase MRP
C    Mitochondrial ribonuclease P
C    Other mitochondrial DNA transcription and translation factors
D      CWS_01340 era; GTP-binding protein Era	K03595 era; GTPase 
D      CWS_00615 tyrosyl-tRNA synthetase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] 
D      CWS_02320 leuS; leucyl-tRNA synthetase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] 
D      CWS_01645 aspS; aspartyl-tRNA synthetase	K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] 
D      CWS_01280 argS; arginyl-tRNA synthetase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] 
B  Mitochondrial DNA replication factors
C    Mitochondrial DNA polymerase
C    Mitochondrial DNA maintenance factors
C    Other Mitochondrial DNA replication factors
D      CWS_02810 single-strand binding protein	K03111 ssb; single-strand DNA-binding protein 
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A<b>Mitochondrial protein import machinery</b>
B  Endoplasmic reticulum membrane and cytosol
C    ER-mitochondria encounter structure (ERMES) complex
C    Other ER-memrane and cytosol factors
B  Outer membrane
C    Transporter outer membrane (TOM) complex
C    TOB/SAM complex
D      CWS_01250 YaeT	K07277 SAM50; outer membrane protein insertion porin family 
C    Porin
C    ERMES complex
C    Other outer membrane factor
B  Inter membrane space
C    Transporter inner membrane (TIM) 9/10 complex
C    TIM8/13 complex
C    Mitochondrial intermembrane space assembly (MIA) complex
B  Inner mambrane
C    MICOS complex
C    MICOS complex (yeast)
C    TIM22 complex
C    TIM23 complex
C    Mitochondrial calcium uniporter complex
C    Other inner membrane factors
B  Matrix
C    MMC/PAM proteins
D      CWS_00800 dnaK; molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK 
D      CWS_00970 heat shock protein GrpE2	K03687 GRPE; molecular chaperone GrpE 
D      CWS_01315 heat shock protein GrpE1	K03687 GRPE; molecular chaperone GrpE 
C    Other matrix factors
D      CWS_00095 groEL; chaperonin GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      CWS_00090 groES; co-chaperonin GroES	K04078 groES; chaperonin GroES 
D      CWS_00795 chaperone protein DnaJ	K03686 dnaJ; molecular chaperone DnaJ 
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A<b>Mitochondrial quality control factors</b>
B  Regulator of mitochondrial biogenesis
C    Ubiquitas transcription factors
D      CWS_02725 elongation factor G	K02355 fusA; elongation factor G 
C    Nuclear respiratory factors
C    Coactivators
C    Proteins involved in Fe-S cluster biogenesis
D      CWS_03085 cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
D      CWS_00800 dnaK; molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK 
D      CWS_03095 chaperone protein HscB	K04082 hscB; molecular chaperone HscB 
D      CWS_00985 glutaredoxin 4 (YdhD)	K07390 grxD; monothiol glutaredoxin 
C    Other regulator of mitochondrial biogenesis
B  Mitochondrial respiratory chain complex assembly factors
C    Complex-I assembly factors
C    Complex-II assembly factors
C    Complex-III assembly factors
C    Complex-IV assembly factors
D      CWS_02440 protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141] 
D      CWS_00080 60 kDa inner-membrane protein	K03217 yidC; YidC/Oxa1 family membrane protein insertase 
C    Complex-V assembly factors
B  Mitochondrial dynamics
C    Fission and Fusion factors
C    Actin cytoskeleton organization
C    Mitochondrial movement
C    Retention of mitochondria
C    Morphogenesis factors
B  Mitophagy factors
C    Autophagy-related proteins
C    Parkin-dependent mechanism factors
C    Parkin-independent mechanism factors
D      CWS_02515 heat shock protein 90	K04079 HSP90A; molecular chaperone HtpG 
C    Other mitophagy factors
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#Last updated: March 14, 2024