+F Repair protein KO
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DNA Repair and Recombination Proteins - Bifidobacterium longum DJO10A
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BLD_1102 ada; Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E BLD_1990 ung; Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BLD_0967 mutY; A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BLD_1195 nth; Putative EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D BLD_0240 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BLD_0307 dut; dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BLD_1102 ada; Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E BLD_1990 ung; Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BLD_0967 mutY; A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BLD_0730 tag; 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E BLD_1195 nth; Putative EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E BLD_0258 xthA; Exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E BLD_0486 nfo; Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E BLD_0066 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E BLD_0836 uvrA2; Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
E BLD_0427 uvrA1; Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
E BLD_0743 uvrB; DNA excision repair enzyme Helicase subunit K03702 uvrB; excinuclease ABC subunit B
E BLD_0428 uvrC; Excinuclease Nuclease subunit K03703 uvrC; excinuclease ABC subunit C
E BLD_0627 uvrD2; Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BLD_0110 uvrD1; Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BLD_0954 uvrD3; Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BLD_0066 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F BLD_0965 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F BLD_0964 rpoC; DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F BLD_1733 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F BLD_1964 rpoZ; DNA-directed RNA polymerase subunit K K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F BLD_0777 mfd; Transcription-repair coupling factor (superfamily II helicase) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E BLD_1928 xseA; Exonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E BLD_1927 xseB; Exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E BLD_0145 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E BLD_1435 dnaN; DNA polymerase sliding clamp subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E BLD_0332 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E BLD_1274 dnaX1; DNA polymerase III gamma/tau subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E BLD_0088 polC; DNA polymerase III alpha subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BLD_1289 dnaX2; DNA polymerase III gamma/tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E BLD_0066 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E BLD_0627 uvrD2; Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BLD_0110 uvrD1; Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BLD_0954 uvrD3; Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BLD_1218 ssb2; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BLD_1907 ssb3; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BLD_1177 ssb1; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BLD_1917 vsr; Very short patch repair (Vsr) endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E BLD_0284 recA; RecA/RadA recombinase K03553 recA; recombination protein RecA
E BLD_0452 ruvA; Holliday junction resolvasome DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E BLD_0453 ruvB; Holliday junction resolvasome helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BLD_0451 ruvC; Holliday junction resolvasome endonuclease subunit K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E BLD_1968 priA; Primosomal protein N'-superfamily II helicase K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E BLD_0284 recA; RecA/RadA recombinase K03553 recA; recombination protein RecA
E BLD_1747 sms2; Putative ATP-dependent serine protease K04485 radA; DNA repair protein RadA/Sms
E BLD_1434 recF; Recombinational DNA repair ATPase K03629 recF; DNA replication and repair protein RecF
E BLD_1087 recG; RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BLD_1518 Putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BLD_1402 Hypothetical transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BLD_0636 Putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BLD_1961 Putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BLD_0118 recO; Recombinational DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
E BLD_1288 recR; Recombinational DNA repair protein K06187 recR; recombination protein RecR
E BLD_0793 recN; ATPase for DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
E BLD_0452 ruvA; Holliday junction resolvasome DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E BLD_0453 ruvB; Holliday junction resolvasome helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BLD_0451 ruvC; Holliday junction resolvasome endonuclease subunit K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E BLD_1903 Hypothetical protein for probable DNA repair K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F BLD_1431 gyrA; Type IIA topoisomerase A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BLD_0303 parA; DNA topoisomerase plasmid partition protein A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BLD_1432 gyrB; Type IIA topoisomerase B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F BLD_0298 parB; DNA topoisomerase plasmid partition protein B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F BLD_1276 topA; Topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F BLD_1976 himA; Bacterial nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F BLD_0118 recO; Recombinational DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
F BLD_1288 recR; Recombinational DNA repair protein K06187 recR; recombination protein RecR
F BLD_0066 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F BLD_0911 recQ; Superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BLD_0836 uvrA2; Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
F BLD_0427 uvrA1; Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
F BLD_0743 uvrB; DNA excision repair enzyme Helicase subunit K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D BLD_1686 dinP2; Nucleotidyltransferase/DNA polymerase for DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D BLD_0871 dinP1; Nucleotidyltransferase/DNA polymerase for DNA repair K03502 umuC; DNA polymerase V
D BLD_0755 lexA2; SOS-response transcriptional repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D BLD_0284 recA; RecA/RadA recombinase K03553 recA; recombination protein RecA
D BLD_0167 lexA1; SOS-response transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D BLD_0793 recN; ATPase for DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
D BLD_0372 Hypothetical protein K14160 imuA; protein ImuA
D BLD_1218 ssb2; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BLD_1907 ssb3; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BLD_1177 ssb1; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BLD_1522 Hypothetical protein K14623 dinD; DNA-damage-inducible protein D
D BLD_0285 oraA; Hypothetical protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D BLD_0301 lhr; Lhr-like helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D BLD_0240 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BLD_1592 mutT3; NTP pyrophosphohydrolase for oxidative damage repair K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D BLD_0307 dut; dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D BLD_1462 nrdA; Ribonucleotide reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BLD_1464 nrdF; Ribonucleotide reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024