+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Crocodylus porosus (Australian saltwater crocodile)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 109317026 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 109311853 RNGTT; mRNA-capping enzyme isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 109307988 CDK7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 109319841 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 109310445 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 109309075 FAM103A1; RNMT-activating mini protein K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 109323581 NCBP1; nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 109310972 NCBP2; nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 109310472 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 109315509 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 109318141 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 109306812 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 109321695 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 109311661 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 109314688 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 109314925 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 109321853 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 109313683 pre-mRNA 3'-end-processing factor FIP1-like isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 109315284 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 109324600 serine/threonine-protein phosphatase PP1-gamma catalytic subunit-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 109324617 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 109319809 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 109314402 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 109318773 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 109311025 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 109321043 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
D U7-dependent histone pre-mRNA processing factors
E 109313130 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 109312835 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 109316075 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 109318564 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 109309871 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 109321695 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 109311661 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 109311025 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 109322304 histone RNA hairpin-binding protein-like isoform X1 K18710 SLBP; histone RNA hairpin-binding protein
E 109322311 histone RNA hairpin-binding protein-like K18710 SLBP; histone RNA hairpin-binding protein
E 109311867 CASP8AP2; CASP8-associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 109317654 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
D N6-methyltransferase complex
E 109309355 METTL14; N6-adenosine-methyltransferase subunit METTL14 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 109317801 METTL4; methyltransferase-like protein 4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 109319186 METTL16; methyltransferase-like protein 16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 109320074 WTAP; pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 109320456 KIAA1429; protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 109317459 RBM15; putative RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 109318260 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 109306507 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 109315716 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 109321735 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 109319575 PAPOLG; poly(A) polymerase gamma isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 109307994 PAPD4; poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 109323016 BARD1; BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 109305503 RBM26; RNA-binding protein 26 K13192 RBM26; RNA-binding protein 26
E 109310512 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 109314662 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 109314473 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 109317175 DHX40; probable ATP-dependent RNA helicase DHX40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 109315818 KIN; DNA/RNA-binding protein KIN17 K13102 KIN; DNA/RNA-binding protein KIN17
D 109322486 METTL8; LOW QUALITY PROTEIN: methyltransferase-like protein 8 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 109313481 METTL22; methyltransferase-like protein 22 isoform X1 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 109311818 FAM46A; protein FAM46A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 109318620 FAM46B; protein FAM46B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 109319166 FAM46C; protein FAM46C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 109311070 protein FAM46D-like K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 109321664 ZC3H14; zinc finger CCCH domain-containing protein 14 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 109324091 RBM8A; RNA-binding protein 8A isoform X1 K12876 RBM8A; RNA-binding protein 8A
E 109307488 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 109319452 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 109311247 CCDC174; coiled-coil domain-containing protein 174 isoform X1 K25178 CCDC174; coiled-coil domain-containing protein 174
E 109320401 CASC3; protein CASC3 K14323 CASC3; protein CASC3
E 109306673 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 109321402 PNN; pinin K13114 PNN; pinin
E 109318397 SRRM1; serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 109317854 THOC1; THO complex subunit 1 isoform X1 K12878 THOC1; THO complex subunit 1
E 109313569 THOC2; THO complex subunit 2 isoform X1 K12879 THOC2; THO complex subunit 2
E 109310230 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 109312933 THOC5; LOW QUALITY PROTEIN: THO complex subunit 5 homolog K13174 THOC5; THO complex subunit 5
E 109311206 THOC7; THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 109306295 PCID2; PCI domain-containing protein 2 isoform X1 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 109309045 SEM1; 26S proteasome complex subunit DSS1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 109321352 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 109313658 CETN2; centrin-2 K10840 CETN2; centrin-2
E 109313659 centrin-1-like K10840 CETN2; centrin-2
E 109308096 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 109322467 MCM3AP; germinal-center associated nuclear protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 109307227 TPR; nucleoprotein TPR isoform X1 K09291 TPR; nucleoprotein TPR
E 109318782 RAE1; mRNA export factor K14298 RAE1; mRNA export factor
E 109311130 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 109316555 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 109315060 NUP85; nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 109320120 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 109316338 NUP50; nuclear pore complex protein Nup50 isoform X1 K14295 NUP50; nuclear pore complex protein Nup50
E 109309475 NUP54; nucleoporin p54 K14308 NUP54; nuclear pore complex protein Nup54
E 109313639 NUP62CL; nucleoporin-62 C-terminal-like protein K14306 NUP62; nuclear pore complex protein Nup62
E 109316922 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 109310469 NUP93; nuclear pore complex protein Nup93 K14309 NUP93; nuclear pore complex protein Nup93
E 109305576 NUP98; nuclear pore complex protein Nup98-Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 109315519 NUP107; nuclear pore complex protein Nup107 isoform X1 K14301 NUP107; nuclear pore complex protein Nup107
E 109319996 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 109313913 NUP188; nucleoporin NUP188 homolog isoform X1 K14311 NUP188; nuclear pore complex protein Nup188
E 109313108 NUP153; nuclear pore complex protein Nup153 K14296 NUP153; nuclear pore complex protein Nup153
E 109307844 NUP155; nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 109318250 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 109323134 NUP35; nucleoporin NUP53 K14313 NUP35; nuclear pore complex protein Nup53
E 109316803 NUP205; nuclear pore complex protein Nup205 K14310 NUP205; nuclear pore complex protein Nup205
E 109311404 NUP210; nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 109324784 NUP210L; nuclear pore membrane glycoprotein 210-like K14314 NUP210; nuclear pore complex protein Nup210
E 109313950 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 109317631 POM121; nuclear envelope pore membrane protein POM 121 isoform X1 K14316 POM121; nuclear pore complex protein Nup121
E 109306649 NUP58; nucleoporin p58/p45 K14307 NUPL1; nucleoporin p58/p45
E 109309727 NUPL2; nucleoporin-like protein 2 K14321 NUPL2; nucleoporin-like protein 2
E 109307008 NDC1; nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 109317085 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 109306272 E3 SUMO-protein ligase RanBP2-like isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 109323439 AAAS; aladin K14320 AAAS; aladin
E 109308096 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 109313903 GLE1; nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 109313717 NXT2; NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 109312996 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 109309214 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 109324940 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 109320492 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 109307460 ELAVL4; ELAV-like protein 4 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 109310229 FAF2; FAS-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 109307796 VCP; transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 109320704 VCPKMT; protein-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 109319565 XPO1; exportin-1 isoform X1 K14290 XPO1; exportin-1
E 109317432 XPO7; exportin-7 isoform X1 K18460 XPO7; exportin-7
E 109309942 RANBP17; ran-binding protein 17 isoform X1 K24115 RANBP17; Ran-binding protein 17
E 109316723 RANGAP1; ran GTPase-activating protein 1 isoform X1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 109316995 TAF15; TATA-binding protein-associated factor 2N isoform X1 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 109308281 EIF4E2; eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 109322212 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 109309877 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 109308478 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 109314306 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 109320756 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 109308493 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 109316927 EIF4H; eukaryotic translation initiation factor 4H K24086 EIF4H; translation initiation factor 4H
E 109317424 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 109312494 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 109309837 EIF4EBP3; eukaryotic translation initiation factor 4E-binding protein 3 K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
E 109312855 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 109321335 ANGEL1; protein angel homolog 1 K18729 ANGEL; protein angel
E 109319062 ANGEL2; protein angel homolog 2 K18729 ANGEL; protein angel
E 109308467 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 109313627 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 109310209 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 109305467 CYFIP1; cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 109310197 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 109322293 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 109308830 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109322161 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109310023 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109324176 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109305910 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 109315269 GIGYF2; PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 109321055 PABPC1; polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 109318362 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 109313169 PABPC1L; polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 109307879 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 109309928 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 109318211 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 109313573 MCTS1; malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 109312612 DENR; density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 109316287 APOBEC1; C->U-editing enzyme APOBEC-1 isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 109312527 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 109322713 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 109317124 MSI2; RNA-binding protein Musashi homolog 2 K14411 MSI; RNA-binding protein Musashi
E 109312315 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 109313014 MSI1; RNA-binding protein Musashi homolog 1 K14411 MSI; RNA-binding protein Musashi
E 109320205 HBS1L; HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 109307897 PELO; protein pelota homolog K06965 PELO; protein pelota
E 109310715 PABPN1L; embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 109314370 ATP-dependent RNA helicase DDX19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 109317973 DDX25; ATP-dependent RNA helicase DDX25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 109318601 RCC1; regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 109308755 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 109324946 la-related protein 6-like K18733 LARP6; la-related protein 6
E 109309835 PURA; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 109317293 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 109316844 POLDIP3; polymerase delta-interacting protein 3 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 109317758 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform X1 K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 109308823 PATL2; protein PAT1 homolog 2 isoform X1 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 109309938 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 109313526 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A K03267 ERF3; peptide chain release factor subunit 3
E 109312344 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 109315808 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 109306280 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 109313584 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 109310091 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 109322290 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 109310036 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 109324178 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 109324543 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 109321088 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 109315263 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 109306143 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 109321765 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 109319434 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 109319707 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 109320655 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 109314567 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 109323684 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 109317260 telomerase-binding protein EST1A-like K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 109307201 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 109317178 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 109315269 GIGYF2; PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 109323357 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 109309043 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 109316682 GTPBP1; GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 109323625 PUM3; LOW QUALITY PROTEIN: pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 109307664 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 109309010 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 109309011 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
E 109324900 unconventional myosin-Vb-like isoform X1 K10357 MYO5; myosin V
E 109316495 BICD1; protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
E 109311332 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 109321124 EXD1; piRNA biogenesis protein EXD1 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 109307935 ACTBL2; beta-actin-like protein 2 K05692 ACTB_G1; actin beta/gamma 1
E 109314696 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 109314911 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 109308866 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 109309184 actin, cytoplasmic 2-like K05692 ACTB_G1; actin beta/gamma 1
E 109316615 MBP; myelin basic protein isoform X1 K17269 MBP; myelin basic protein
E 109306692 VIM; vimentin K07606 VIM; vimentin
E 109312346 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 109312823 T-box transcription factor TBX6-like K10180 TBX6; T-box protein 6
E 109312824 T-box-containing protein TBX6L K10180 TBX6; T-box protein 6
D Trans-acting binding proteins
E 109318788 ZBP1; Z-DNA-binding protein 1 K12965 ZBP1; Z-DNA binding protein 1
E 109306983 FUBP1; far upstream element-binding protein 1 K13210 FUBP; far upstream element-binding protein
E 109313943 FUBP3; far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 109322035 elongation factor 1-alpha-like K03231 EEF1A; elongation factor 1-alpha
E 109311797 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 109318376 elongation factor 1-alpha, oocyte form-like K03231 EEF1A; elongation factor 1-alpha
E 109318847 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 109309977 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 109308614 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 109313138 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 109319599 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 109309743 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 109312289 PTBP1; polypyrimidine tract-binding protein 1 isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 109308830 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109322161 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109310023 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109324176 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 109308467 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 109313627 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 109310209 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 109305467 CYFIP1; cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 109323354 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 109323050 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 109311432 PCBP4; poly(rC)-binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 109313731 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 109321098 CAPRIN1; caprin-1 K18743 CAPRIN1; caprin-1
E 109316487 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 109314505 YBX1; LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 109308590 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 109322186 AGO2; protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 109318454 AGO4; protein argonaute-4 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 109318455 protein argonaute-3 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 109308281 EIF4E2; eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 109322212 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 109309877 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 109312344 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 109305910 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 109318104 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 109323597 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 109324901 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 109305652 FASTK; fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 109310348 LSM14A; protein LSM14 homolog A K18749 LSM14; protein LSM14
E 109318815 LSM14B; protein LSM14 homolog B K18749 LSM14; protein LSM14
E 109323354 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 109314505 YBX1; LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 109310607 WTIP; Wilms tumor protein 1-interacting protein K16682 AJUBA; LIM domain-containing protein
E 109311536 LIMD1; LIM domain-containing protein 1 isoform X1 K16682 AJUBA; LIM domain-containing protein
E 109316287 APOBEC1; C->U-editing enzyme APOBEC-1 isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 109317870 MOV10; putative helicase MOV-10 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 109318385 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 109308044 TNPO1; transportin-1 K18752 TNPO1; transportin-1
E 109314567 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 109323684 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 109317260 telomerase-binding protein EST1A-like K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 109307201 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 109321251 ZFP36L1; mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 109311900 LIN28B; protein lin-28 homolog B K18754 LIN28; protein lin-28
E 109318541 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 109322114 HTT; huntingtin isoform X1 K04533 HD; huntingtin
E 109316485 IPO8; importin-8 isoform X1 K18755 IPO8; importin-8
E 109323900 BICC1; protein bicaudal C homolog 1 K18756 BICC1; protein bicaudal C
E 109322713 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 109307348 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 109309291 LARP1B; la-related protein 1B K18757 LARP1; la-related protein 1
E 109309868 LARP1; la-related protein 1 K18757 LARP1; la-related protein 1
E 109312657 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 109308180 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 109311329 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 109316458 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 109317421 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 109311251 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 109312356 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 109312305 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 109309648 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 109315629 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 109319432 KLC4; kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 109320609 KLC1; kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 109307664 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 109309010 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 109309011 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
E 109324900 unconventional myosin-Vb-like isoform X1 K10357 MYO5; myosin V
E 109308321 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 109315845 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 109315855 tubulin alpha-3 chain-like isoform X1 K07374 TUBA; tubulin alpha
E 109316442 TUBA8; tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 109316445 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 109317566 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 109308830 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109322161 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109310023 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109324176 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 109310197 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 109322293 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 109314589 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 109315124 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 109316707 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 109310438 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 109315499 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 109316805 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 109310136 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 109324387 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 109322178 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 109310199 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 109310604 uncharacterized protein KIAA0355 homolog K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 109308517 DIS3L2; DIS3-like exonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 109322944 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 109306629 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 109315016 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 109316731 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 109316867 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 109317765 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 109317960 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 109312855 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 109324629 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 109308860 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 109310415 EDC4; enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 109315808 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 109306280 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 109313584 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 109311008 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 109319895 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 109305527 ZAR1L; ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 109318593 YTHDF2; YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
E 109318837 YTHDF1; YTH domain-containing family protein 1 isoform X1 K20102 YTHDF; YTH domain-containing family protein
E 109319054 YTHDF3; YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 109317345 TIA1; nucleolysin TIA-1 isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 109324088 TIAL1; nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 109321055 PABPC1; polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 109318362 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 109313169 PABPC1L; polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 109313138 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 109319599 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 109308467 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 109313627 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 109318788 ZBP1; Z-DNA-binding protein 1 K12965 ZBP1; Z-DNA binding protein 1
E 109320492 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 109310188 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 109309515 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 109308339 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 109314724 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 109308478 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 109319452 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 109314306 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 109320756 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 109308493 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 109311055 RPS6KA6; ribosomal protein S6 kinase alpha-6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 109318635 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 109305989 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 109320045 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 109313783 TRAF2; TNF receptor-associated factor 2 isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 109306464 TDRD3; tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 109324401 LARP4; la-related protein 4 K18763 LARP4; la-related protein 4
E 109307068 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 109311329 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 109316458 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 109308180 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 109318104 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 109308860 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 109310415 EDC4; enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 109324629 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 109317421 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 109311251 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 109312356 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 109312305 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 109309648 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 109315629 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 109308590 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 109315886 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 109317986 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
C 3'-5' decay
D Core exosome factors
E 109323834 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 109313945 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 109324292 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 109311579 EXOSC7; exosome complex component RRP42 isoform X1 K12589 RRP42; exosome complex component RRP42
E 109306580 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 109309327 EXOSC9; exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 109306444 DIS3; exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 109309194 DIS3L; DIS3-like exonuclease 1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 109314532 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 109319528 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 109310656 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 109309602 probable ATP-dependent RNA helicase DDX60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 109310536 PAPD5; non-canonical poly(A) RNA polymerase PAPD5 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 109314253 PAPD7; non-canonical poly(A) RNA polymerase PAPD7 isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 109323490 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 109307911 SKIV2L2; superkiller viralicidic activity 2-like 2 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 109308118 TTC37; tetratricopeptide repeat protein 37 K12600 SKI3; superkiller protein 3
E 109308909 WDR61; WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 109310136 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 109324387 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 109310438 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 109315499 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 109316805 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 109322178 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 109310199 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 109322500 CNOT9; cell differentiation protein RCD1 homolog K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 109310995 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 109322944 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 109306629 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 109313513 PARN; poly(A)-specific ribonuclease PARN isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 109320070 PNLDC1; poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 109308357 DHX36; ATP-dependent RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 109315016 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 109316731 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 109316867 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 109317765 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 109317960 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 109309613 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 109309467 ERI1; 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 109314847 ERI2; ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 109317986 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 109311307 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 109308907 IREB2; iron-responsive element-binding protein 2 K22416 IREB2; iron-responsive element-binding protein 2
E 109318721 HELZ2; helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 109321678 NRDE2; protein NRDE2 homolog K26109 NRDE2; nuclear exosome regulator NRDE2
E 109320897 SAMD4A; protein Smaug homolog 1 K27396 SMG; protein Smaug
E 109323362 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 109310861 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 109318572 ZC3H12A; endoribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 109306691 ZC3H12C; probable ribonuclease ZC3H12C isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 109320127 ZC3H12D; probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 109314730 DROSHA; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 109324509 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 109314446 ENO1; alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 109319385 ENO2; gamma-enolase isoform X1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 109319586 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 109308666 PFKL; ATP-dependent 6-phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 109323417 PFKM; ATP-dependent 6-phosphofructokinase, muscle type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 109307117 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 109309936 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 109322650 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 109313945 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 109323834 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 109311579 EXOSC7; exosome complex component RRP42 isoform X1 K12589 RRP42; exosome complex component RRP42
D Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024