+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Crassostrea gigas (Pacific oyster)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 105345793 mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 105322687 mRNA-capping enzyme K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 105317788 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 105339251 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 105322668 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 105333004 translation initiation factor IF-2 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 105318090 nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 105323733 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 105329073 cleavage and polyadenylation specificity factor subunit 5 isoform X1 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 105325886 cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 105326854 polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 105338678 pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 105342117 cleavage and polyadenylation specificity factor subunit 1 isoform X1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 105319344 cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 105319722 cleavage and polyadenylation specificity factor subunit 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 105338165 cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 105318324 pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 105333261 pre-mRNA 3' end processing protein WDR33 K15542 PFS2; polyadenylation factor subunit 2
E 105334335 WD repeat-containing protein 82-like K14962 WDR82; COMPASS component SWD2
E 105320999 serine/threonine-protein phosphatase alpha-2 isoform K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 105326211 serine/threonine-protein phosphatase alpha-2 isoform K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 105337924 serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 105318349 serine/threonine-protein phosphatase alpha-2 isoform isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 117689358 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 105333262 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 105323009 cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 105331297 cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 105347665 cleavage stimulation factor subunit 3-like K14408 CSTF3; cleavage stimulation factor subunit 3
E 105342182 symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 105345314 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 105347083 small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 105328191 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 105346836 small nuclear ribonucleoprotein G-like K11099 SNRPG; small nuclear ribonucleoprotein G
E 105347156 U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 105319344 cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 105319722 cleavage and polyadenylation specificity factor subunit 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 105331297 cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 105342182 symplekin K06100 SYMPK; symplekin
E 105337739 histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
D DRB sensitivity inducing factor (DSIF) complex
E 105347027 transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 105323274 transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 105329074 N6-adenosine-methyltransferase subunit METTL3 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 105326041 N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 105333744 N(6)-adenine-specific methyltransferase METTL4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 105347004 RNA N6-adenosine-methyltransferase mettl16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 105346270 pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 105339257 protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 117680637 protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 105342534 RNA-binding protein spenito K13190 RBM15; RNA-binding protein 15
E 105330720 zinc finger CCCH domain-containing protein 13 isoform X1 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 105346475 E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 105324541 poly(A) polymerase beta isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 105328584 poly(A) RNA polymerase GLD2 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 105339907 speckle targeted PIP5K1A-regulated poly(A) polymerase isoform X1 K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
E 105339926 poly(A) RNA polymerase, mitochondrial K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 105324607 BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 105330918 RNA demethylase ALKBH5 isoform X1 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 105321705 TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
E 105333799 TAR DNA-binding protein 43 isoform X2 K23600 TARDBP; TAR DNA-binding protein 43
E 105348874 TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 105344782 DNA/RNA-binding protein KIN17 K13102 KIN; DNA/RNA-binding protein KIN17
D 105322553 methyltransferase-like protein 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 105335437 terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 105317409 zinc finger CCCH domain-containing protein 14 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 105326707 serrate RNA effector molecule homolog isoform X1 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 105348755 RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 105337940 protein mago nashi homolog 2 K12877 MAGOH; protein mago nashi
E 105322560 THO complex subunit 4 isoform X1 K12881 THOC4; THO complex subunit 4
E 105319208 spliceosome RNA helicase DDX39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 105319209 spliceosome RNA helicase DDX39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 105335655 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 105318756 coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 105345158 protein CASC3 isoform X1 K14323 CASC3; protein CASC3
E 105347084 histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 105322973 pinin K13114 PNN; pinin
E 105337759 apoptotic chromatin condensation inducer in the nucleus-like K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 105321021 RNA-binding protein with serine-rich domain 1-B K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 105331448 serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 105338779 THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 105330153 THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E 105337779 microfibril-associated glycoprotein 4 K12880 THOC3; THO complex subunit 3
E 105317884 THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 105336393 THO complex subunit 3-like isoform X1 K12880 THOC3; THO complex subunit 3
E 105345709 THO complex subunit 3 isoform X1 K12880 THOC3; THO complex subunit 3
E 105335058 LOW QUALITY PROTEIN: THO complex subunit 3-like K12880 THOC3; THO complex subunit 3
E 105322560 THO complex subunit 4 isoform X1 K12881 THOC4; THO complex subunit 4
E 105332689 THO complex subunit 5 homolog isoform X1 K13174 THOC5; THO complex subunit 5
E 105346723 THO complex subunit 6 homolog K13175 THOC6; THO complex subunit 6
E 105342267 THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 105331153 PCI domain-containing protein 2-like K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 105322792 26S proteasome complex subunit SEM1-like K10881 SHFM1; 26 proteasome complex subunit DSS1
E 117683313 26S proteasome complex subunit SEM1-like K10881 SHFM1; 26 proteasome complex subunit DSS1
E 105330451 transcription and mRNA export factor ENY2 isoform X1 K11368 ENY2; enhancer of yellow 2 transcription factor
E 105341222 caltractin K10840 CETN2; centrin-2
E 105331093 caltractin-like isoform X1 K10840 CETN2; centrin-2
E 117681840 caltractin K10840 CETN2; centrin-2
E 105328266 calmodulin-like protein 30 K10840 CETN2; centrin-2
E 105336998 centrin-3 K16466 CETN3; centrin-3
E 105340178 germinal-center associated nuclear protein isoform X3 K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 105325437 nucleoprotein TPR isoform X3 K09291 TPR; nucleoprotein TPR
E 105336642 mRNA export factor K14298 RAE1; mRNA export factor
E 105342784 protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 105330288 nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 105347350 nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 105322538 nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 105343646 nucleoporin p54 isoform X1 K14308 NUP54; nuclear pore complex protein Nup54
E 105325291 nuclear pore glycoprotein p62 isoform X1 K14306 NUP62; nuclear pore complex protein Nup62
E 105324858 nucleoporin 88 K14318 NUP88; nuclear pore complex protein Nup88
E 105334708 nuclear pore complex protein Nup93 K14309 NUP93; nuclear pore complex protein Nup93
E 105320975 nuclear pore complex protein Nup98-Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 105337474 nuclear pore complex protein Nup98-Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 105346252 nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 105339546 nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 105334941 nucleoporin NUP188 homolog isoform X3 K14311 NUP188; nuclear pore complex protein Nup188
E 105322206 nuclear pore complex protein Nup50 isoform X1 K14296 NUP153; nuclear pore complex protein Nup153
E 105338117 putative GPI-anchored protein pfl2 isoform X2 K14296 NUP153; nuclear pore complex protein Nup153
E 105348482 nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 105341923 nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 105344637 nucleoporin NUP35 K14313 NUP35; nuclear pore complex protein Nup53
E 105340039 nuclear pore complex protein Nup205 K14310 NUP205; nuclear pore complex protein Nup205
E 105330354 nuclear pore membrane glycoprotein 210-like K14314 NUP210; nuclear pore complex protein Nup210
E 105324883 nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 105344104 nuclear pore complex protein Nup58 isoform X1 K14307 NUPL1; nucleoporin p58/p45
E 105347373 nucleoporin NUP42 isoform X1 K14321 NUPL2; nucleoporin-like protein 2
E 105320638 nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 105328593 nucleoporin SEH1 K14299 SEH1; nucleoporin SEH1
E 105323093 E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 105331213 aladin isoform X1 K14320 AAAS; aladin
E 117684001 aladin-like isoform X1 K14320 AAAS; aladin
E 105336998 centrin-3 K16466 CETN3; centrin-3
E 105329976 nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 105322156 nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
D Ran-mediated transport factors
E 105327885 GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 105342498 acidic leucine-rich nuclear phosphoprotein 32-related protein isoform X1 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 105329647 ELAV-like protein 2 K13088 ELAVL1; ELAV-like protein 1
E 105335107 LOW QUALITY PROTEIN: ELAV-like protein 1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 105329644 ELAV-like protein 3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 105324082 FAS-associated factor 2 isoform X1 K18726 FAF2; FAS-associated factor 2
E 105326153 transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 105325921 protein-lysine methyltransferase METTL21D isoform X1 K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 105345320 exportin-1 K14290 XPO1; exportin-1
E 117685979 exportin-7-like isoform X1 K18460 XPO7; exportin-7
E 105341517 exportin-7-like K18460 XPO7; exportin-7
E 105341516 exportin-7-like isoform X1 K18460 XPO7; exportin-7
E 105331767 ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 105335954 RNA-binding protein FUS isoform X1 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 105327880 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 105324495 ATP-dependent RNA helicase eIF4A K03257 EIF4A; translation initiation factor 4A
E 105323723 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 105345876 eukaryotic translation initiation factor 4 gamma 1 isoform X4 K03260 EIF4G; translation initiation factor 4G
E 105317347 eukaryotic translation initiation factor 4 gamma 2-like K03260 EIF4G; translation initiation factor 4G
E 105330136 eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 109617380 eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 105327861 eukaryotic translation initiation factor 4H K24086 EIF4H; translation initiation factor 4H
E 105341698 eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 105325906 nuclear receptor coactivator 6 isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 105332122 protein angel homolog 2 isoform X1 K18729 ANGEL; protein angel
E 105342998 fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 105329452 cytoplasmic FMR1-interacting protein-like isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 105325321 cytoplasmic FMR1-interacting protein isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 105333390 uncharacterized protein LOC105333390 K13133 GEMIN5; gem associated protein 5
E 105327757 gem-associated protein 5-like K13133 GEMIN5; gem associated protein 5
E 105339299 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 105339684 cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 105341865 ATP-dependent RNA helicase DDX3Y isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 117690312 ATP-dependent RNA helicase DDX3Y-like K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 105330258 GRB10-interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 105317918 polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 105326555 LOW QUALITY PROTEIN: polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 105326399 polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 105323966 polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 105331411 polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 117690339 polyadenylate-binding protein-interacting protein 2-like K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 117680483 helicase SKI2W-like K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 105336194 helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 105343605 deformed epidermal autoregulatory factor 1 homolog isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 105340398 malignant T-cell-amplified sequence 1 homolog isoform X1 K07575 MCTS; malignant T-cell-amplified sequence
E 105338124 density-regulated protein homolog K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 105341857 APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 105330886 partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 105326545 DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 105336239 RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 105347411 HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 105338398 protein pelota K06965 PELO; protein pelota
E 105334534 polyadenylate-binding protein 2-B K14396 PABPN1; polyadenylate-binding protein 2
E 105338838 ATP-dependent RNA helicase DDX19A isoform X1 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 117680746 ATP-dependent RNA helicase DDX19A-like isoform X1 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 105337236 pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 105335950 SAP domain-containing ribonucleoprotein isoform X2 K18732 SARNP; SAP domain-containing ribonucleoprotein
E 105320914 regulator of chromosome condensation isoform X1 K11493 RCC1; regulator of chromosome condensation
E 105317819 la-related protein 6 isoform X1 K18733 LARP6; la-related protein 6
E 105322217 transcriptional activator protein Pur-beta-B isoform X1 K21772 PURA; transcriptional activator protein Pur-alpha
E 105329478 uncharacterized protein LOC105329478 K22414 POLDIP3; polymerase delta-interacting protein 3
E 105340493 zinc finger CCCH domain-containing protein 11A K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 105336386 leukocyte receptor cluster member 8 homolog K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E 105325000 eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 105339845 eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1 K03267 ERF3; peptide chain release factor subunit 3
E 105331061 regulator of nonsense transcripts 1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 105344597 regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 105322817 regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 105341231 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 105343833 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like isoform X1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 105320707 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 105339916 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 105345875 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X2 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 105337161 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 105324454 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 117689403 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 105347393 serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 105345495 protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 105321652 telomerase-binding protein EST1A K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 105339479 protein SMG7 K14409 SMG7; protein SMG7
E 105322808 protein SMG8 isoform X2 K18734 SMG8; protein SMG8
E 105332655 protein SMG9 K18735 SMG9; protein SMG9
E 105330258 GRB10-interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 117687431 selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 105329690 selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 105344130 probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 105320610 probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 105335507 LOW QUALITY PROTEIN: GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 105336671 pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 105330929 unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 105340000 protein bicaudal D isoform X3 K18739 BICD; protein bicaudal D
E 105320375 uncharacterized protein LOC105320375 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105320376 uncharacterized protein LOC105320376 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105340033 uncharacterized protein LOC105340033 isoform X2 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105343835 uncharacterized protein LOC105343835 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105347982 uncharacterized protein LOC105347982 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 117681691 uncharacterized protein LOC117681691 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105326641 uncharacterized protein LOC105326641 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 117681692 uncharacterized protein LOC117681692 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 117681819 uncharacterized protein LOC117681819 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105342861 uncharacterized protein LOC105342861 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105334795 piRNA biogenesis protein EXD1 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 105320374 uncharacterized protein LOC105320374 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 105326705 actin, cytoplasmic K05692 ACTB_G1; actin beta/gamma 1
E 105332192 actin-5 K05692 ACTB_G1; actin beta/gamma 1
E 105332193 actin, cytoplasmic K05692 ACTB_G1; actin beta/gamma 1
E 105340468 actin-2 K05692 ACTB_G1; actin beta/gamma 1
E 117680327 actin-85C-like isoform X1 K05692 ACTB_G1; actin beta/gamma 1
E 105335713 actin, adductor muscle K05692 ACTB_G1; actin beta/gamma 1
E 117692766 actin-6-like K05692 ACTB_G1; actin beta/gamma 1
E 105326698 actin-like K05692 ACTB_G1; actin beta/gamma 1
E 105335284 actin-like K05692 ACTB_G1; actin beta/gamma 1
E 117684888 actin-3-like K05692 ACTB_G1; actin beta/gamma 1
E 105340471 LOW QUALITY PROTEIN: actin K05692 ACTB_G1; actin beta/gamma 1
E 117680516 actin-like K05692 ACTB_G1; actin beta/gamma 1
E 105328443 actin-1 K05692 ACTB_G1; actin beta/gamma 1
E 105328556 actin-1 K05692 ACTB_G1; actin beta/gamma 1
E 105332777 actin-5 K05692 ACTB_G1; actin beta/gamma 1
E 105332779 actin-3 K05692 ACTB_G1; actin beta/gamma 1
E 117690321 actin-3-like K05692 ACTB_G1; actin beta/gamma 1
E 105339321 T-box-containing protein TBX6L isoform X2 K10180 TBX6; T-box protein 6
E 105348851 uncharacterized protein LOC105348851 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 105324686 far upstream element-binding protein 1 isoform X1 K13210 FUBP; far upstream element-binding protein
E 105338957 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
E 105345227 elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 105324050 elongation factor 1-gamma-like K03233 EEF1G; elongation factor 1-gamma
E 105333434 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X2 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 105340833 HCLS1-associated protein X-1 isoform X1 K16220 HAX1; HCLS1-associated protein X-1
E 105331152 arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 105331923 double-stranded RNA-binding protein Staufen homolog isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 105339299 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 105339684 cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 105342998 fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 105329452 cytoplasmic FMR1-interacting protein-like isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 105325321 cytoplasmic FMR1-interacting protein isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 105333153 poly(rC)-binding protein 3 isoform X3 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 105340513 caprin-1 isoform X1 K18743 CAPRIN1; caprin-1
E 105318040 Y-box factor homolog K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 105340192 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 105321320 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 105329532 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 117684746 LOW QUALITY PROTEIN: protein argonaute-2-like K11593 ELF2C; eukaryotic translation initiation factor 2C
E 105327880 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 105331061 regulator of nonsense transcripts 1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 105341865 ATP-dependent RNA helicase DDX3Y isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 117690312 ATP-dependent RNA helicase DDX3Y-like K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 105330037 ATP-dependent RNA helicase me31b K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 105328416 RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 105328630 protein LSM14 homolog A-A isoform X1 K18749 LSM14; protein LSM14
E 105318040 Y-box factor homolog K09276 YBX1; Y-box-binding protein 1
E 105326215 Wilms tumor protein 1-interacting protein homolog K16682 AJUBA; LIM domain-containing protein
E 105319269 putative helicase MOV-10 isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 105318490 transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 105347393 serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 105345495 protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 105321652 telomerase-binding protein EST1A K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 105339479 protein SMG7 K14409 SMG7; protein SMG7
E 105336839 LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 105346268 protein lin-28 homolog isoform X1 K18754 LIN28; protein lin-28
E 105336135 huntingtin K04533 HD; huntingtin
E 105325916 protein bicaudal C homolog 1-like K18756 BICC1; protein bicaudal C
E 105336635 cAMP-dependent protein kinase catalytic subunit 1 isoform X2 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 105331323 la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 105344721 ataxin-2-like protein isoform X3 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 105349067 m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 105345995 mRNA-decapping enzyme 1A K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 105346630 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 105330850 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 105323611 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 105348485 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 105321817 U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 105322958 U6 snRNA-associated Sm-like protein LSm6 isoform X1 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 105334675 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 105340617 kinesin light chain isoform X1 K10407 KLC; kinesin light chain
E 105330929 unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 105329640 tubulin alpha chain, testis-specific K07374 TUBA; tubulin alpha
E 117683631 tubulin alpha-1A chain-like K07374 TUBA; tubulin alpha
E 105329346 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 105329348 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 109618881 tubulin alpha-1A chain-like isoform X1 K07374 TUBA; tubulin alpha
E 117684542 tubulin alpha chain K07374 TUBA; tubulin alpha
E 105347346 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 105347347 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 105342358 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 117682163 tubulin alpha-8 chain-like isoform X1 K07374 TUBA; tubulin alpha
E 105339299 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 105339684 cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 105333390 uncharacterized protein LOC105333390 K13133 GEMIN5; gem associated protein 5
E 105327757 gem-associated protein 5-like K13133 GEMIN5; gem associated protein 5
E 105325598 trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 105324909 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 105320796 CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 117691467 CCR4-NOT transcription complex subunit 2-like isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 105332581 CCR4-NOT transcription complex subunit 3 isoform X3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 105322221 CCR4-NOT transcription complex subunit 4 isoform X2 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 105348954 uncharacterized protein LOC105348954 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 105337935 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 105325230 DIS3-like exonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 105333996 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 105333885 PAN2-PAN3 deadenylation complex subunit pan3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 105317912 maternal B9.10 protein isoform X1 K14443 TOB; protein Tob/BTG
E 105340066 Btg1; uncharacterized protein LOC105340066 K14443 TOB; protein Tob/BTG
E 105325609 protein Tob1-like K14443 TOB; protein Tob/BTG
E 105325906 nuclear receptor coactivator 6 isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 105343604 protein PAT1 homolog 1-like isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 105346914 enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 105322464 enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 105344597 regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 105322817 regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
E 105326086 E3 ubiquitin-protein ligase TRIM71 isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 105338381 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 105340780 transcription intermediary factor 1-alpha isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 105343535 RING finger protein nhl-1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 117691620 E3 ubiquitin-protein ligase TRIM71-like K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 117683561 E3 ubiquitin-protein ligase TRIM71-like K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 117692219 E3 ubiquitin-protein ligase TRIM71-like K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 105319613 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 105348558 YTH domain-containing family protein 3 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 105320706 nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 105317918 polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 105326555 LOW QUALITY PROTEIN: polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 105326399 polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 105323966 polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 105331923 double-stranded RNA-binding protein Staufen homolog isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 105342998 fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 105329647 ELAV-like protein 2 K13088 ELAVL1; ELAV-like protein 1
E 105347201 ras GTPase-activating protein-binding protein 2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 105333810 eukaryotic translation initiation factor 2A isoform X1 K15026 EIF2A; translation initiation factor 2A
E 105332194 eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 105324495 ATP-dependent RNA helicase eIF4A K03257 EIF4A; translation initiation factor 4A
E 105323723 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 105335655 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 109617380 eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 105345876 eukaryotic translation initiation factor 4 gamma 1 isoform X4 K03260 EIF4G; translation initiation factor 4G
E 105317347 eukaryotic translation initiation factor 4 gamma 2-like K03260 EIF4G; translation initiation factor 4G
E 105330136 eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 105329220 ribosomal protein S6 kinase alpha-3 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 105341228 guanine nucleotide-binding protein subunit beta-2-like 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 105344264 TNF receptor-associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 105332371 TNF receptor-associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 105322156 nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 105331484 tudor domain-containing protein 3 K18404 TDRD3; tudor domain-containing protein 3
E 105325596 la-related protein 4 isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 105345995 mRNA-decapping enzyme 1A K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 105349067 m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 105330037 ATP-dependent RNA helicase me31b K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 105346914 enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 105322464 enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 105343604 protein PAT1 homolog 1-like isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 105346630 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 105330850 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 105323611 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 105348485 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 105321817 U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 105322958 U6 snRNA-associated Sm-like protein LSm6 isoform X1 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 105334675 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
D 5' exonucleases
E 105340192 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 105345357 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 109618305 U8 snoRNA-decapping enzyme K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 105342540 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 105337397 probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 105328567 exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 105321222 exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 105331407 LOW QUALITY PROTEIN: exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 105331037 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 105339181 exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 105330577 exosome complex component MTR3-like K12587 MTR3; exosome complex component MTR3
E 105329651 exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 105327745 exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 105348766 exosome complex component RRP45 isoform X1 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 105341733 exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 105322274 DIS3-like exonuclease 1 isoform X2 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 105330593 LOW QUALITY PROTEIN: exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 105324260 nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 105336031 M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E 105345609 terminal nucleotidyltransferase 4B K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 117684767 zinc finger CCHC domain-containing protein 7-like K12597 AIR1_2; protein AIR1/2
E 105341233 exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 117680483 helicase SKI2W-like K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 105336194 helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 105344506 tetratricopeptide repeat protein 37 K12600 SKI3; superkiller protein 3
E 105335189 WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 105348954 uncharacterized protein LOC105348954 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 105324909 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 105320796 CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 117691467 CCR4-NOT transcription complex subunit 2-like isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 105332581 CCR4-NOT transcription complex subunit 3 isoform X3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 105322221 CCR4-NOT transcription complex subunit 4 isoform X2 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 105337935 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 105348977 CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 105338377 CCR4-NOT transcription complex subunit 10 isoform X1 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 105333996 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 105333885 PAN2-PAN3 deadenylation complex subunit pan3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 105335764 poly(A)-specific ribonuclease PARN K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 105331025 poly(A)-specific ribonuclease PNLDC1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 105345676 ATP-dependent DNA/RNA helicase DHX36-like K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 105317912 maternal B9.10 protein isoform X1 K14443 TOB; protein Tob/BTG
E 105340066 Btg1; uncharacterized protein LOC105340066 K14443 TOB; protein Tob/BTG
E 105325609 protein Tob1-like K14443 TOB; protein Tob/BTG
E 105336378 nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 105327396 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 105340363 ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 105342540 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 105320749 2',5'-phosphodiesterase 12 isoform X1 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 105337397 probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 105318266 helicase with zinc finger domain 2 isoform X1 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 105335192 helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 117684919 helicase with zinc finger domain 2-like K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 105340146 helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 105323546 helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 105340096 helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 105347778 helicase with zinc finger domain 2 isoform X2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 105318265 helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 105347983 nuclear exosome regulator NRDE2-like K26109 NRDE2; nuclear exosome regulator NRDE2
E 105318125 protein Smaug homolog 1 K27396 SMG; protein Smaug
E 105347554 focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 105327943 uncharacterized protein LOC105327943 isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 105327664 ribonuclease 3 isoform X1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 105338621 probable oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
E 117693110 ATP-dependent DNA helicase Q-like 3 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 117685686 ATP-dependent DNA helicase RecQ-like K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 117685996 Werner syndrome ATP-dependent helicase homolog K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 105329363 ATP-dependent DNA helicase Q-like SIM K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 105348008 probable ATP-dependent DNA helicase RecS K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 105328115 ATP-dependent DNA helicase RecQ isoform X1 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 109617800 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 109619424 probable ATP-dependent DNA helicase RecS K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 117688168 ATP-dependent DNA helicase RecQ-like isoform X1 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 109621022 ATP-dependent DNA helicase Q-like 3 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 117688812 ATP-dependent DNA helicase Q-like 3 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 105324005 Bloom syndrome protein homolog K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 109617963 ATP-dependent DNA helicase Q-like SIM K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 105334541 ATP-dependent DNA helicase Q-like SIM K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 117689866 ATP-dependent DNA helicase Q-like 3 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 117690569 ATP-dependent DNA helicase Q-like SIM isoform X1 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
E 117690753 Werner syndrome ATP-dependent helicase-like K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D Other RNA degradosome components
E 105334471 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 105328565 polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 105330927 ATP-dependent 6-phosphofructokinase isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 105347255 stress-70 protein, mitochondrial isoform X1 K04043 dnaK; molecular chaperone DnaK
E 105348623 heat shock protein 60A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 105321222 exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 105328567 exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 105331037 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 105329651 exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024