+D Chaperone KO
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Chaperones and Folding Catalysts - Drosophila navojoa
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AHeat shock proteins
B HSP110
C 108651228 heat shock 70 kDa protein 4 isoform X1 K09485 HSP110; heat shock protein 110kDa
C 115564352 hypoxia up-regulated protein 1 K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C 108657336 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C 108650751 heat shock protein 83 K04079 HSP90A; molecular chaperone HtpG
C 108660127 endoplasmin K09487 HSP90B; heat shock protein 90kDa beta
C 108654016 heat shock protein 75 kDa, mitochondrial K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C 115562272 heat shock 70 kDa protein cognate 2 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 115565506 major heat shock 70 kDa protein Ba K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108650444 heat shock 70 kDa protein cognate 4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108650680 heat shock 70 kDa protein cognate 1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108658722 heat shock protein 68 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108656817 endoplasmic reticulum chaperone BiP K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C 108654845 heat shock 70 kDa protein cognate 5 K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C 108659211 T-complex protein 1 subunit alpha K09493 CCT1; T-complex protein 1 subunit alpha
C 115564903 T-complex protein 1 subunit alpha-like isoform X1 K09493 CCT1; T-complex protein 1 subunit alpha
C 108656360 T-complex protein 1 subunit beta K09494 CCT2; T-complex protein 1 subunit beta
C 108659399 T-complex protein 1 subunit gamma K09495 CCT3; T-complex protein 1 subunit gamma
C 108649984 T-complex protein 1 subunit delta K09496 CCT4; T-complex protein 1 subunit delta
C 108654352 T-complex protein 1 subunit epsilon K09497 CCT5; T-complex protein 1 subunit epsilon
C 108657500 T-complex protein 1 subunit zeta K09498 CCT6; T-complex protein 1 subunit zeta
C 108660387 T-complex protein 1 subunit eta K09499 CCT7; T-complex protein 1 subunit eta
C 108653397 T-complex protein 1 subunit theta K09500 CCT8; T-complex protein 1 subunit theta
C 108656580 heat shock protein 60A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
C 108658671 60 kDa heat shock protein homolog 2, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
C 115561982 60 kDa heat shock protein homolog 1, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C 108659579 dnaJ homolog subfamily A member 4 K09502 DNAJA1; DnaJ homolog subfamily A member 1
C 108649832 dnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
C 108654696 protein tumorous imaginal discs, mitochondrial isoform X1 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 108654738 dnaJ homolog subfamily C member 21 K09506 DNAJA5; DnaJ homolog subfamily A member 5
C 108651060 dnaJ protein homolog 1 K09510 DNAJB4; DnaJ homolog subfamily B member 4
C 115565460 dnaJ protein homolog 1-like K09510 DNAJB4; DnaJ homolog subfamily B member 4
C 115562152 dnaJ protein homolog 1 isoform X1 K09511 DNAJB5; DnaJ homolog subfamily B member 5
C 108654836 dnaJ homolog subfamily B member 2 isoform X1 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 115561993 dnaJ homolog shv K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 108659212 dnaJ homolog subfamily B member 12 K09518 DNAJB12; DnaJ homolog subfamily B member 12
C 108653287 dnaJ homolog subfamily B member 1 K09518 DNAJB12; DnaJ homolog subfamily B member 12
C 108656769 uncharacterized protein F54F2.9 K09521 DNAJC1; DnaJ homolog subfamily C member 1
C 108651781 dnaJ homolog subfamily C member 2 K09522 DNAJC2; DnaJ homolog subfamily C member 2
C 108660309 dnaJ homolog subfamily C member 3 K09523 DNAJC3; DnaJ homolog subfamily C member 3
C 108653933 dnaJ-like protein 60 isoform X1 K09524 DNAJC4; DnaJ homolog subfamily C member 4
C 108651849 dnaJ homolog subfamily C member 5 homolog isoform X1 K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 108649344 dnaJ homolog subfamily C member 7 isoform X1 K09527 DNAJC7; DnaJ homolog subfamily C member 7
C 108654961 dnaJ homolog subfamily C member 8 isoform X1 K09528 DNAJC8; DnaJ homolog subfamily C member 8
C 108659323 J domain-containing protein CG6693 K09529 DNAJC9; DnaJ homolog subfamily C member 9
C 108654846 dnaJ homolog subfamily C member 11 K09531 DNAJC11; DnaJ homolog subfamily C member 11
C 108656972 J domain-containing protein isoform X1 K09532 DNAJC12; DnaJ homolog subfamily C member 12
C 108654113 dnaJ homolog subfamily C member 13 isoform X1 K09533 DNAJC13; DnaJ homolog subfamily C member 13
C 108659658 AF4/FMR2 family member 4 isoform X1 K09534 DNAJC14; DnaJ homolog subfamily C member 14
C 108651289 dnaJ homolog subfamily C member 16 K09536 DNAJC16; DnaJ homolog subfamily C member 16
C 115564463 dnaJ homolog subfamily C member 17 K09537 DNAJC17; DnaJ homolog subfamily C member 17
C 108650982 mitochondrial import inner membrane translocase subunit TIM14 isoform X1 K09539 DNAJC19; DnaJ homolog subfamily C member 19
C 108656446 dnaJ homolog subfamily C member 22 isoform X1 K19370 DNAJC22; DnaJ homolog subfamily C member 22
C 108651501 translocation protein SEC63 homolog K09540 SEC63; translocation protein SEC63
C 108656136 dnaJ homolog subfamily C member 25 homolog K19371 DNAJC25; DnaJ homolog subfamily C member 25
C 115562855 dnaJ homolog subfamily C member 28 K19373 DNAJC28; DnaJ homolog subfamily C member 28
C 108659129 dnaJ homolog subfamily C member 30, mitochondrial K19374 DNAJC30; DnaJ homolog subfamily C member 30
C 108652206 iron-sulfur cluster co-chaperone protein HscB K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
C 108654129 grpE protein homolog, mitochondrial K03687 GRPE; molecular chaperone GrpE
C 115565215 grpE protein homolog, mitochondrial-like K03687 GRPE; molecular chaperone GrpE
B HSP20
C 108654377 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
B HSP15
B HSP10
C 108651473 10 kDa heat shock protein, mitochondrial isoform X1 K04078 groES; chaperonin GroES
C 115564018 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
B GimC
C 115563328 prefoldin subunit 1 K09548 PFDN1; prefoldin subunit 1
C 108651932 probable prefoldin subunit 2 K09549 PFDN2; prefoldin subunit 2
C 108650781 probable prefoldin subunit 4 K09550 PFDN4; prefoldin subunit 4
C 108659214 probable prefoldin subunit 5 isoform X1 K04797 pfdA; prefoldin alpha subunit
C 108650527 probable prefoldin subunit 6 K04798 pfdB; prefoldin beta subunit
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AOther chaperones and cochaperones
B Calnexin / calreticulin
C 108660170 calnexin K08054 CANX; calnexin
C 108659804 calreticulin K08057 CALR; calreticulin
B DegP / HtrA
C 108660102 LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
B AAA proteases
C 108657493 paraplegin K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C 108651013 AFG3-like protein 2 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C 108649988 stress-induced-phosphoprotein 1 K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C 108652068 hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
B BAG
C 115563891 BAG family molecular chaperone regulator 2 isoform X1 K09556 BAG2; BCL2-associated athanogene 2
B Others
C 108656679 hsc70-interacting protein 1-like isoform X1 K09560 ST13; suppressor of tumorigenicity protein 13
C 108649508 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 108652551 hsp70 nucleotide exchange factor fes1 K09562 HSPBP1; hsp70-interacting protein
C 108651650 HSPB1-associated protein 1 K19375 HSPBAP1; HSPB1-associated protein 1
C 108652048 protein OPI10 homolog K23327 HIKESHI; protein Hikeshi
C 108660399 cysteine and histidine-rich domain-containing protein K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 108659766 methyltransferase-like protein 23 K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C 108659121 protein unc-45 homolog B K21991 UNC45; protein unc-45
C 108651006 protein canopy homolog 4 K22816 CNPY3_4; protein canopy 3/4
C 108657328 torsin-like protein K22990 TOR1; torsin-1
C 108655458 SPARC K24262 SPARC; secreted protein acidic and rich in cysteine
C 108649498 small glutamine-rich tetratricopeptide repeat-containing protein beta K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C 108653127 tetratricopeptide repeat protein 1 K24926 TTC1; tetratricopeptide repeat protein 1
C 115564451 tetratricopeptide repeat protein 4 K24927 TTC4; tetratricopeptide repeat protein 4
C 115563620 coiled-coil domain-containing protein 47 K24962 CCDC47; PAT complex subunit CCDC47
C 108651203 protein Asterix K24963 WDR83OS; PAT complex subunit Asterix
C 108653100 LDLR chaperone boca K25366 MESD; LRP chaperone MESD
C 108654196 uncharacterized protein LOC108654196 isoform X1 K26164 RIC3; protein RIC-3
C 115563381 activator of 90 kDa heat shock protein ATPase homolog 1 K26216 AHSA1; activator of Hsp90 ATPase protein 1
C 108650363 transmembrane protein 35A K26241 NACHO; novel acetylcholine receptor chaperone
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AIntramolecular chaperones
B Subtilisin family
C 108650338 membrane-bound transcription factor site-1 protease K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C 108652955 furin-like protease 1 isoform X1 K01349 FURIN; furin [EC:3.4.21.75]
C 108659743 neuroendocrine convertase 2 K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C 108655463 furin-like protease 2 isoform X1 K08654 PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
C 108653662 tripeptidyl-peptidase 2 K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C 108656605 cathepsin B K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 108652824 cathepsin L1-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 115565210 cathepsin L1-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 108650696 cathepsin L1-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 108654417 cathepsin L1 K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 108654424 cathepsin L K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 108655106 cathepsin L1 K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
C 108649789 zinc carboxypeptidase K08779 CPA1; carboxypeptidase A1 [EC:3.4.17.1]
B Others
C 108650945 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 108657090 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 108651797 hemocytin K03900 VWF; von Willebrand factor
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D 115562052 peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 108654490 peptidyl-prolyl cis-trans isomerase 6 K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 108650498 peptidyl-prolyl cis-trans isomerase D K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
D 108658817 peptidyl-prolyl cis-trans isomerase E K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D 108657651 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 108652555 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 108657015 peptidyl-prolyl cis-trans isomerase K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 108650529 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 108659114 peptidyl-prolyl cis-trans isomerase G isoform X1 K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D 108654286 peptidyl-prolyl cis-trans isomerase H K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 108658953 peptidyl-prolyl cis-trans isomerase-like 1 K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D 108654574 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D 108653376 peptidyl-prolyl cis-trans isomerase-like 3 K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D 115564157 peptidyl-prolyl cis-trans isomerase sig-7 K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D 108655018 peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform X1 K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D 108652544 spliceosome-associated protein CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 108651890 E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D 108654393 12 kDa FK506-binding protein K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D 108659701 FK506-binding protein 2 K09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]
D 115562948 FK506-binding protein 59 K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 108653753 inactive peptidyl-prolyl cis-trans isomerase shutdown K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D 108653945 peptidyl-prolyl cis-trans isomerase FKBP8 K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
D 108653777 FK506-binding protein 2 isoform X1 K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D 108651197 uncharacterized protein LOC108651197 K27238 BDBT; bride of doubletime
C Parvulin
D 115565130 putative peptidyl-prolyl cis-trans isomerase dodo K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D 108657656 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C 108651723 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 108653146 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 108655993 thioredoxin-2 K03671 TXN; thioredoxin
C 108657591 thioredoxin-1 K03671 TXN; thioredoxin
C 108656310 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 108658849 thioredoxin-2 isoform X1 K03671 TXN; thioredoxin
C 108655539 thioredoxin-1-like K03671 TXN; thioredoxin
C 108651497 thioredoxin-2 K03671 TXN; thioredoxin
C 115565168 thioredoxin-1-like K03671 TXN; thioredoxin
C 115564171 glutaredoxin-C4 K03676 grxC; glutaredoxin 3
C 115565591 glutaredoxin K03676 grxC; glutaredoxin 3
C 108656187 glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
C 108658201 glutaredoxin domain-containing cysteine-rich protein CG31559-like K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C 115565459 glutaredoxin domain-containing cysteine-rich protein CG12206-like K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C 108660164 glutaredoxin domain-containing cysteine-rich protein CG31559 K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C 108651433 protein disulfide-isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 108654366 protein disulfide-isomerase A3 K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 115563760 protein disulfide-isomerase A5 K09583 PDIA5; protein disulfide-isomerase A5 [EC:5.3.4.1]
C 108658799 protein disulfide-isomerase A6 homolog isoform X1 K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 115563234 protein disulfide-isomerase A6 homolog K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 115563000 thioredoxin domain-containing protein 5-like K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 108657124 thioredoxin domain-containing protein 5 homolog K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 108652205 protein disulfide-isomerase TMX3 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
C 115562854 cysteine-rich with EGF-like domain protein 2 isoform X1 K24335 CRELD; protein disulfide-isomerase [EC:5.3.4.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024