+E Ubiquitin system KO
#
Ubiquitin System - Drosophila willistoni
%
!
AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 6648626 LOW QUALITY PROTEIN: polyubiquitin-C K08770 UBC; ubiquitin C
C 6644337 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 6653185 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 6644204 NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 6638664 uncharacterized protein LOC6638664 K02983 RP-S30e; small subunit ribosomal protein S30e
C 6648942 small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
C 6643616 small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
C 6649626 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 6644665 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 6639043 autophagy protein 12-like K08336 ATG12; ubiquitin-like protein ATG12
C 6639146 ubiquitin-related modifier 1 homolog K12161 URM1; ubiquitin related modifier 1
C 26529108 ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 6640855 ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 6650270 SUMO-activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 6643157 SUMO-activating enzyme subunit 2-B K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 6640603 nedd8-activating enzyme E1 catalytic subunit K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 6646351 nedd8-activating enzyme E1 regulatory subunit K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 6646750 adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 6648687 ubiquitin-like modifier-activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 6640454 ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
#
AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 6651616 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 6645043 ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 6647220 ubiquitin-conjugating enzyme E2-17 kDa K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 6644644 ubiquitin-conjugating enzyme E2 4 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 6641753 ubiquitin-conjugating enzyme E2-24 kDa K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 6644724 ubiquitin-conjugating enzyme E2 11 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 6650407 ubiquitin-conjugating enzyme E2 G1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 6651641 ubiquitin-conjugating enzyme E2 G1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 6653088 ubiquitin-conjugating enzyme E2 G2 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 6648420 ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 6647238 ubiquitin-conjugating enzyme E2 4 K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 6650485 ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 6639531 ubiquitin-conjugating enzyme E2-22 kDa K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 6648027 ubiquitin-conjugating enzyme E2-18 kDa K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 6643323 ubiquitin-conjugating enzyme E2-18 kDa K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 6638682 ubiquitin-conjugating enzyme E2-18 kDa K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 6648262 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 6640366 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 6650757 (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 6643966 ubiquitin-conjugating enzyme E2Q-like protein CG4502 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 6638102 ubiquitin-conjugating enzyme E2 Q2 isoform X1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 6645818 ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 6644491 ubiquitin-conjugating enzyme E2 S isoform X1 K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 6639848 ubiquitin-conjugating enzyme E2 W isoform X2 K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 6651097 baculoviral IAP repeat-containing protein 6 isoform X7 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 6644049 SUMO-conjugating enzyme UBC9-B K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 6645404 nedd8-conjugating enzyme UbcE2M K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 6645431 ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 6640432 ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 6637886 ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
#
AUbiquitin ligases (E3)
B HECT type E3
C 6639616 ubiquitin-protein ligase E3A K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 6646329 ubiquitin-protein ligase E3B K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 6640784 ubiquitin-protein ligase E3C K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 6641422 uncharacterized protein LOC6641422 K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 6637860 E3 ubiquitin-protein ligase Smurf1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 6642501 E3 ubiquitin-protein ligase Su(dx) K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 6650628 E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 6646088 E3 ubiquitin-protein ligase Nedd-4 isoform X7 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 6641095 E3 ubiquitin-protein ligase HUWE1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 6642503 apoptosis-resistant E3 ubiquitin protein ligase 1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 6650847 E3 ubiquitin-protein ligase hyd K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 6644642 PHD finger protein 7 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 6641165 G2/M phase-specific E3 ubiquitin-protein ligase K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 6641492 probable E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 6645726 probable E3 ubiquitin-protein ligase HERC4 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 6649116 E3 ubiquitin-protein ligase HECW2 isoform X1 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 6653305 E3 ubiquitin-protein ligase Ufd4 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 6646321 NEDD4 family-interacting protein 1-like isoform X2 K25839 NDFIP; NEDD4 family-interacting protein
B U-box type E3
C 6643680 ubiquitin conjugation factor E4 A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 6642344 ubiquitin conjugation factor E4 B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 6641854 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 6638271 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 6652443 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 6639972 E3 ubiquitin ligase PARAQUAT TOLERANCE 3 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 6650897 RING finger protein 37 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 6639175 E3 ubiquitin-protein ligase Bre1 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 6646101 E3 ubiquitin-protein ligase CBL-B-B K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 6642991 E3 ubiquitin-protein ligase sina K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 6642992 probable E3 ubiquitin-protein ligase sinah K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
C Ligand of Numb proteins
D 6651372 slo-interacting protein 1 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 6639399 putative uncharacterized protein DDB_G0277255 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 6652188 uncharacterized protein LOC6652188 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 6641116 E3 ubiquitin-protein ligase MARCHF5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 6650035 E3 ubiquitin-protein ligase MARCHF5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 6648882 E3 ubiquitin-protein ligase MARCHF5-like K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 6645073 E3 ubiquitin-protein ligase MARCHF6 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D 6643475 protein shuttle craft isoform X1 K12236 NFX1; transcriptional repressor NF-X1
D 6651926 NF-X1-type zinc finger protein NFXL1 isoform X1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 6646998 protein pellino K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 6645133 peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 6643912 peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 6645301 peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 6639572 E3 ubiquitin-protein ligase parkin isoform X1 K04556 PARK2; parkin [EC:2.3.2.31]
D 6644728 E3 ubiquitin-protein ligase ariadne-1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 6638370 potential E3 ubiquitin-protein ligase ariadne-2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 26528805 E3 ubiquitin-protein ligase RNF19A K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 6643971 E3 ubiquitin-protein ligase lubel isoform X3 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 6638188 uncharacterized protein LOC6638188 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
C TRAF proteins
D 6641099 TNF receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 124459655 brain tumor protein K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 6641975 E3 ubiquitin-protein ligase TRIM9 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 6649494 transcription intermediary factor 1-alpha isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 6642872 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 6638499 RING finger protein nhl-1 isoform X9 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 6637969 protein wech K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D 6644824 E3 ubiquitin-protein ligase Ubr3 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 6642618 protein purity of essence isoform X1 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 6643748 putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 6640629 death-associated inhibitor of apoptosis 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 6646469 death-associated inhibitor of apoptosis 1 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 26529493 death-associated inhibitor of apoptosis 1 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 6650538 BRCA1-associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 6642834 E3 ubiquitin-protein ligase Hakai K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 6653196 putative general negative regulator of transcription C16C9.04c K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 6638772 protein sneaky K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 6641199 protein deltex K06058 DTX; deltex [EC:2.3.2.27]
D 6646981 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 6647010 E3 ubiquitin-protein ligase Kcmf1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 6643464 E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 6648858 E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 6643205 E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 6651369 RNA-binding protein MEX3B isoform X1 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 6643819 E3 ubiquitin-protein ligase MIB2 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 6646506 E3 ubiquitin-protein ligase mind-bomb K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 6642926 probable E3 ubiquitin-protein ligase makorin-1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 6645929 mitochondrial E3 ubiquitin protein ligase 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 26528991 mitochondrial E3 ubiquitin protein ligase 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 6641243 E3 ubiquitin-protein ligase highwire K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 6643424 E3 ubiquitin-protein ligase MYLIP-B K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 6647015 protein neuralized isoform X2 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 6646711 RING finger and CHY zinc finger domain-containing protein 1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 6643014 roquin-1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 6645439 E3 ubiquitin-protein ligase RFWD3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 6647165 E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 6650102 uncharacterized protein LOC6650102 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 26528967 uncharacterized protein LOC26528967 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 6644497 uncharacterized protein LOC6644497 isoform X1 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 6649252 E3 ubiquitin-protein ligase RNF185 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 26530137 RING finger protein 10 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 6651639 RING finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 6650921 E3 ubiquitin-protein ligase RNF13 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 6646138 E3 ubiquitin-protein ligase RNF25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 6642001 uncharacterized protein LOC6642001 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 6647869 uncharacterized protein DDB_G0283357 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 6646492 E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 6639195 E3 ubiquitin-protein ligase NRDP1-like K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 6644065 E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 6647878 uncharacterized protein LOC6647878 K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D 6646861 E3 ubiquitin-protein ligase Iruka K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 6649221 RING finger protein 121 K15698 RNF121_175; RING finger protein 121/175
D 6650559 E3 ubiquitin-protein ligase RNF123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 6647319 protein TRC8 homolog isoform X1 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 6645447 E3 ubiquitin-protein ligase rnf146 isoform X1 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 6648513 E3 ubiquitin ligase Rnf157 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 6651014 E3 ubiquitin-protein ligase RNF181 homolog K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 111519511 E3 ubiquitin-protein ligase RNF181 homolog K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 6647216 E3 ubiquitin-protein ligase Rnf220 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 6642583 U4/U6.U5 tri-snRNP-associated protein 1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 6639358 E3 ubiquitin-protein ligase SHPRH K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 6640342 E3 ubiquitin-protein ligase SH3RF1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 6650190 E3 ubiquitin-protein ligase HRD1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 6650037 E3 ubiquitin-protein ligase TM129 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 6652344 E3 ubiquitin-protein ligase TRAIP K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 6651095 RING finger protein unkempt isoform X2 K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 6639732 E3 ubiquitin-protein ligase ZNF598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 6644605 E3 ubiquitin-protein ligase znrf2 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
B Atypical E3
C 6643703 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 6644663 probable E3 ubiquitin-protein ligase IRF2BPL K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 6646946 E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 6652424 E3 SUMO-protein ligase PIAS3 isoform X2 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 6653133 E3 SUMO-protein ligase MMS21 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 6640739 RING finger protein nenya K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 6648822 RING finger protein vilya K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 124460897 E3 SUMO-protein ligase ZBED1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 124460899 zinc finger BED domain-containing protein 4-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 124460937 zinc finger BED domain-containing protein 4-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 111519443 E3 SUMO-protein ligase ZBED1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 111519577 E3 SUMO-protein ligase ZBED1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 124461154 E3 SUMO-protein ligase ZBED1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 124461195 E3 SUMO-protein ligase ZBED1-like isoform X1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 124461205 E3 SUMO-protein ligase ZBED1-like isoform X1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 124461593 E3 SUMO-protein ligase ZBED1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 111519118 E3 SUMO-protein ligase ZBED1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 6644240 uncharacterized protein LOC6644240 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 6647229 E3 UFM1-protein ligase 1 homolog K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 6651984 DCN1-like protein K17822 DCUN1D1_2; DCN1-like protein 1/2
C 6638187 DCN1-like protein 3 isoform X1 K17823 DCUN1D3; DCN1-like protein 3
C 6638841 DCN1-like protein 5 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 6640400 cullin homolog 1 K03347 CUL1; cullin 1
D Adaptor protein
E 6640606 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6649632 SKP1-like protein 15 K03094 SKP1; S-phase kinase-associated protein 1
E 6643164 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 6646207 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 6648904 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 6639099 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6639196 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6644813 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6652545 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 6650398 F-box/WD repeat-containing protein 11 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 6638730 F-box/WD repeat-containing protein 4 K10262 FBXW4; F-box and WD-40 domain protein 4
E 6642372 F-box/WD repeat-containing protein 5 K10263 FBXW5; F-box and WD-40 domain protein 5
E 6651928 F-box/WD repeat-containing protein 7 K10260 FBXW7; F-box and WD-40 domain protein 7
E 6647714 S-phase kinase-associated protein 2 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 6640397 F-box/LRR-repeat protein 20 isoform X2 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 6648908 F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 6640177 F-box/LRR-repeat protein 6 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 6647104 F-box/LRR-repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 6647818 dynein regulatory complex subunit 6 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 6638475 F-box/LRR-repeat protein 3 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 6647996 jmjC domain-containing histone demethylation protein 1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 6640176 F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 6644434 F-box/LRR-repeat protein 15 isoform X1 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 6645545 F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 6647894 F-box only protein 9 K10295 FBXO9; F-box protein 9
E 6651278 F-box only protein 11 K10297 FBXO11; F-box protein 11
E 6650093 uncharacterized protein LOC6650093 isoform X1 K06084 LMO7; F-box protein 20
E 6645471 F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E 6645840 F-box only protein 28 K10306 FBXO28; F-box protein 28
E 6640570 uncharacterized protein LOC6640570 K10306 FBXO28; F-box protein 28
E 6646491 F-box only protein 33 K10310 FBXO33; F-box protein 33
E 6640714 F-box only protein 39 K10314 FBXO39; F-box protein 39
E 6639717 F-box only protein 42 K10317 FBXO42; F-box protein 42
E 6640642 F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
C Cul2 complex
D Ring finger protein
E 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 26529179 cullin-2 K03870 CUL2; cullin 2
D Adoptor protein
E 6640837 elongin-C K03872 ELOC; elongin-C
E 6649426 elongin-B K03873 ELOB; elongin-B
D Target recognizing subunit
E 6640477 protein Vhl K03871 VHL; von Hippel-Lindau disease tumor supressor
E 6642619 protein PopC K10348 LRR1; LRR-repeat protein 1
E 26530056 LOW QUALITY PROTEIN: leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 124460837 leucine-rich repeat protein 1-like K10348 LRR1; LRR-repeat protein 1
E 124461266 leucine-rich repeat protein 1-like K10348 LRR1; LRR-repeat protein 1
E 124461267 leucine-rich repeat protein 1-like K10348 LRR1; LRR-repeat protein 1
E 26529335 leucine-rich repeat protein 1-like K10348 LRR1; LRR-repeat protein 1
E 124461403 leucine-rich repeat protein 1-like K10348 LRR1; LRR-repeat protein 1
E 6653594 uncharacterized protein LOC6653594 K10348 LRR1; LRR-repeat protein 1
E 111519768 LOW QUALITY PROTEIN: leucine-rich repeat and death domain-containing protein 1-like K10348 LRR1; LRR-repeat protein 1
E 124461492 leucine-rich repeat protein 1-like K10348 LRR1; LRR-repeat protein 1
E 124461697 leucine-rich repeat-containing protein 57-like K10348 LRR1; LRR-repeat protein 1
E 6641875 leucine-rich repeat-containing protein 69 K10348 LRR1; LRR-repeat protein 1
E 6637527 uncharacterized protein LOC6637527 K10348 LRR1; LRR-repeat protein 1
E 6647340 protein fem-1 homolog CG6966 K25805 FEM1A_C; protein fem-1 homolog A/C
E 6646902 protein fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 6640007 protein fem-1 homolog B isoform X1 K10349 FEM1B; protein fem-1 homolog B
E 6653074 amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 6641381 kelch domain-containing protein 3 K25808 KLHDC3; kelch domain-containing protein 3
E 6652446 kelch domain-containing protein 10 homolog K25809 KLHDC10; kelch domain-containing protein 10
E 6638825 protein zer-1 homolog isoform X1 K10350 ZYG11; Zyg-11 protein
E 6641184 zinc finger SWIM domain-containing protein 8 homolog K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 6643610 cullin-3-A isoform X1 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 6648267 kelch-like protein 5 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 6643494 ring canal kelch protein K10443 KLHL2_3; kelch-like protein 2/3
E 6642430 kelch-like protein 10 isoform X3 K10448 KLHL10; kelch-like protein 10
E 6638328 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 6646944 kelch-like protein 18 K10455 KLHL18; kelch-like protein 18
E 6650962 kelch-like ECH-associated protein 1B isoform X2 K10456 KLHL19; kelch-like protein 19
E 6643028 kelch-like protein diablo isoform X1 K10457 KLHL20; kelch-like protein 20
E 6642498 actin-binding protein IPP K13956 IPP; actin-binding protein IPP
E 6647426 LOW QUALITY PROTEIN: BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 6644678 BTB/POZ domain-containing protein 7 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 6644631 BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 6649872 BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 26529532 BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 6649657 BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 6639431 BTB/POZ domain-containing protein KCTD20 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 6638222 protein germ cell-less K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 6638700 ankyrin repeat and BTB/POZ domain-containing protein 2 isoform X1 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 6638787 rho-related BTB domain-containing protein 1 isoform X1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 6640036 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 124461423 BTB/POZ domain-containing protein kctd15-like K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 6643273 BTB/POZ domain-containing protein kctd15-like K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 6652854 BTB/POZ domain-containing protein KCTD5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 6651280 BTB/POZ domain-containing protein KCTD3 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 6649612 BTB/POZ domain-containing protein KCTD12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 6650032 BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 6649478 protein roadkill isoform X1 K10523 SPOP; speckle-type POZ protein
E 6648915 leucine-zipper-like transcriptional regulator 1 homolog K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 6652413 cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 6649634 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 6641922 DET1 homolog K10571 DET1; de-etiolated-1
E 6642830 DET1- and DDB1-associated protein 1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 6646980 protein cereblon isoform X2 K11793 CRBN; cereblon
E 6639629 protein mahjong isoform X1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 6652431 protein lethal(2)denticleless K11790 DTL; denticleless
E 6647198 DDB1- and CUL4-associated factor 5 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 6648690 DDB1- and CUL4-associated factor 6 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 6644572 DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 6639178 uncharacterized protein LOC6639178 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 6639901 WD and tetratricopeptide repeats protein 1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 6648047 DDB1- and CUL4-associated factor 10 homolog K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 6640255 DDB1- and CUL4-associated factor 11 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 6651155 DDB1- and CUL4-associated factor 12 homolog K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 6645731 DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 6647330 uncharacterized protein LOC6647330 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 6650481 bromodomain and WD repeat-containing protein 3 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 6642937 WD repeat-containing protein 26 homolog K22382 WDR26; WD repeat-containing protein 26
E 6643391 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
E 26529403 RING-box protein 2 isoform X1 K10611 RBX2; RING-box protein 2
D Cullin
E 6649840 cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E 6640837 elongin-C K03872 ELOC; elongin-C
E 6649426 elongin-B K03873 ELOB; elongin-B
D Target recognizing subunit
E 6643493 putative mediator of RNA polymerase II transcription subunit 26 K04698 SOCS5; suppressor of cytokine signaling 5
E 6652091 uncharacterized protein LOC6652091 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 6649331 serine-rich adhesin for platelets isoform X1 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 6649547 uncharacterized protein LOC6649547 isoform X1 K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 6642645 protein gustavus isoform X1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 6646495 SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 6644160 SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 6644686 ras-related protein Rab-40C isoform X2 K07928 RAB40; Ras-related protein Rab-40
C Cul7 complex
D Ring finger protein
E 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 6640606 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6649632 SKP1-like protein 15 K03094 SKP1; S-phase kinase-associated protein 1
E 6643164 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 6646207 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 6648904 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 6639099 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6639196 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6644813 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 6652545 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 124461521 LOW QUALITY PROTEIN: RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461729 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461882 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 124461913 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6638168 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6642959 RING-box protein 1B K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6644881 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6645940 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6652807 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 6653602 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E 6646752 anaphase-promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 6640792 anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 6641719 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 6648369 fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 6641286 anaphase-promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
E 6645242 cell division cycle protein 27 homolog K03350 APC3; anaphase-promoting complex subunit 3
E 6649317 anaphase-promoting complex subunit 4 isoform X1 K03351 APC4; anaphase-promoting complex subunit 4
E 6646058 anaphase-promoting complex subunit 5 K03352 APC5; anaphase-promoting complex subunit 5
E 6647563 cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 6648739 anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 6643596 cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 6652100 anaphase-promoting complex subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
E 6652321 anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 6643257 anaphase-promoting complex subunit 15 K25228 APC15; anaphase-promoting complex subunit 15
C BRCC complex
D 6650611 DNA repair protein Rad51 homolog K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 6650559 E3 ubiquitin-protein ligase RNF123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 6640873 ubiquitin-associated domain-containing protein 1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 6643971 E3 ubiquitin-protein ligase lubel isoform X3 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 6652289 E3 ubiquitin-protein ligase RMND5A K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 6646211 ran-binding proteins 9/10 homolog isoform X1 K23334 RANBP9_10; Ran-binding protein 9/10
D 6652380 muskelin isoform X1 K23337 MKLN1; muskelin
D 6650195 E3 ubiquitin-protein transferase MAEA K18624 MAEA; macrophage erythroblast attacher
D 6648888 glucose-induced degradation protein 8-B homolog K23338 GID8; glucose-induced degradation protein 8
D 6652319 glucose-induced degradation protein 8-A homolog K23338 GID8; glucose-induced degradation protein 8
D 6648342 protein yippee K23339 YPEL5; protein yippee-like 5
D 6642937 WD repeat-containing protein 26 homolog K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
D 6650566 protein Lilipod K25215 LMBR1L; protein LMBR1L
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 6641995 cullin-associated NEDD8-dissociated protein 1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 6649708 uncharacterized protein LOC6649708 K22558 COMMD2; COMM domain containing 2
D 6648463 COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 6651967 COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 6641939 COMM domain-containing protein 5 K22561 COMMD5; COMM domain containing 5
D 6648830 uncharacterized protein LOC6648830 K22566 COMMD10; COMM domain containing 10
D 6642994 coiled-coil domain-containing protein 22 homolog K23343 CCDC22; coiled-coil domain-containing protein 22
D 6651052 DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 6646246 glomulin K23345 GLMN; glomulin
D 6644036 UBX domain-containing protein 2 K24350 UBXN7; UBX domain-containing protein 7
D 6640693 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 6652190 protein lingerer isoform X2 K26545 UBAP2; ubiquitin-associated protein 2
D 6652534 SH3 domain-containing protein Dlish K26546 Dlish; SH3 domain-containing protein Dlish
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 6643431 ubiquitin carboxyl-terminal hydrolase calypso K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 6641936 ubiquitin carboxyl-terminal hydrolase K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 6644547 ubiquitin carboxyl-terminal hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
D 6645812 ubiquitin carboxyl-terminal hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 111519113 ubiquitin carboxyl-terminal hydrolase CYLD isoform X1 K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 6649795 ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 6644573 ubiquitin carboxyl-terminal hydrolase Usp2 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 6642114 ubiquitin carboxyl-terminal hydrolase Usp2 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 6646054 ubiquitin carboxyl-terminal hydrolase 5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 6643091 ubiquitin carboxyl-terminal hydrolase 32 isoform X2 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 6649007 ubiquitin carboxyl-terminal hydrolase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 6647283 ubiquitin carboxyl-terminal hydrolase 8 isoform X1 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 6650188 probable ubiquitin carboxyl-terminal hydrolase FAF isoform X4 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 6638603 ubiquitin carboxyl-terminal hydrolase 10 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 6646862 ubiquitin carboxyl-terminal hydrolase 46 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 6644148 ubiquitin carboxyl-terminal hydrolase 14-like K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 6646631 ubiquitin carboxyl-terminal hydrolase 14 isoform X1 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 6641370 ubiquitin carboxyl-terminal hydrolase 45 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 6638153 ubiquitin carboxyl-terminal hydrolase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 6648439 ubiquitin carboxyl-terminal hydrolase 30 homolog K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 6640003 ubiquitin carboxyl-terminal hydrolase 43 isoform X1 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 6647915 ubiquitin carboxyl-terminal hydrolase puf K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 6640985 ubiquitin carboxyl-terminal hydrolase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 6638806 ubiquitin carboxyl-terminal hydrolase 36 isoform X1 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 6638696 ubiquitin carboxyl-terminal hydrolase 47 isoform X1 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
C OTU
D 6653334 ubiquitin thioesterase otubain-like K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 6638977 uncharacterized protein LOC6638977 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 111519749 uncharacterized protein LOC111519749 isoform X1 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 6645729 deubiquitinase OTUD6B K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 6647813 ubiquitin thioesterase trabid K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 6637925 josephin-like protein K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 6652862 ubiquitin carboxyl-terminal hydrolase MINDY-3 homolog K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 6645923 inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 6642003 MPN domain-containing protein CG4751 K24173 MPND; MPN domain-containing protein
D 6641631 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 6651535 STAM-binding protein-like A K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D 6638218 deubiquitinase DESI2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
D 6648360 deubiquitinase DESI2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C 6648907 uncharacterized protein LOC6648907 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 111519062 sentrin-specific protease-like K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 6645084 uncharacterized protein LOC6645084 isoform X1 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 6643342 sentrin-specific protease 8 isoform X1 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 6649264 sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 6641936 ubiquitin carboxyl-terminal hydrolase K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 6647481 uncharacterized protein LOC6647481 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D 6645674 COP9 signalosome complex subunit 1b K12175 GPS1; COP9 signalosome complex subunit 1
D 6643559 COP9 signalosome complex subunit 1 K12175 GPS1; COP9 signalosome complex subunit 1
D 6641686 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 6645669 COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 6640031 COP9 signalosome complex subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D 6650739 COP9 signalosome complex subunit 5 isoform X1 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 6647361 COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 6640377 COP9 signalosome complex subunit 7 K12180 COPS7; COP9 signalosome complex subunit 7
D 6644290 COP9 signalosome complex subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 1, 2024