+E	Ubiquitin system	KO
#<h2><a href="/kegg/kegg2.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Ubiquitin System - Escherichia coli O9 HS (commensal)</h2>
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#<!---
#ENTRY       ecx04121
#NAME        T00591
#DEFINITION  <a href="/kegg/kegg2.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Ubiquitin System - Escherichia coli O9 HS (commensal)
#--->
!
A<b>Ubiquitins and Ubiquitin-like proteins</b>
B  Ubiquitins
B  Ubiquitin-like proteins (UBLs)
#
A<b>Ubiquitin-activating enzymes (E1)</b>
B  Ubiquitin activating enzyme
B  UBL-activating enzymes
C    EcHS_A0884 moeB; molybdopterin synthase sulfurylase MoeB	K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11] 
#
A<b>Ubiquitin-conjugating enzymes (E2)</b>
B  Ubiquitin-conjugating enzymes
B  UBL-conjugating enzymes
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A<b>Ubiquitin ligases (E3)</b>
B  HECT type E3
B  U-box type E3
B  Single Ring-finger type E3
C    BRE1 proteins
C    CBL proteins
C    SINA (Seven in absentia) proteins
C    Ligand of Numb proteins
C    March proteins
C    MDM2/MDM4 proteins
C    NFX1 proteins
C    Pellino proteins
C    Peripheral membrane proteins
C    RBR proteins
C    TRAF proteins
C    TRIM/RBCC proteins
C    UBR box proteins
C    ATL proteins
C    Other single Ring-finger type E3
B  UBL E3 ligases
B  Multi subunit Ring-finger type E3
C    SCF complex
D      Ring finger protein
D      Cullin
D      Adaptor protein
D      Target recognizing subunit (F-box)
C    ECV complex
D      Ring finger protein
D      Cullin
D      Adoptor protein
D      Target recognizing subunit (VHL box)
C    Cul3 complex
D      Ring finger protein
D      Cullin
D      Target recognizing subunit (BTB)
C    Cul4 complex
D      Ring finger protein
D      Cullin
D      Adoptor protein
D      Target recognizing subunit (DCAF)
C    ECS complex
D      Ring finger protein
D      Cullin
D      Adoptor protein
D      Target recognizing subunit (SOCS box)
C    Cul7 complex
D      Ring finger protein
D      Cullin
D      Adaptor protein
D      Target recognizing subunit
C    APC/C
D      Ring finger protein
D      Cullin
D      Target recognizing subunit
D      Other subunits
C    BRCC complex
C    KPC complex
C    LUBAC complex
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A<b>Deubiquitinating enzyme (DUB)</b>
B  Ubiquitin-specific proteases (UBPs)
C    UCH
C    UBP/USP
C    OTU
C    MJD
C    JAMM
C    BRISC complex
B  UBL-specific proteases (ULPs)
C    COP9 signalosome (CSN) complex
!
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#Last updated: October 24, 2016