+D GENES KO #

  KEGG Orthology (KO) - Hyperthermus butylicus

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:hbu00010] D Hbut_1447 universally conserved protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D Hbut_0487 universally conserved uncharacterized protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Hbut_0946 Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Hbut_0939 glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D Hbut_0940 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Hbut_1197 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Hbut_0911 Enolase (2-phosphoglycerate dehydratase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hbut_0985 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0983 2-oxoglutarate synthase subunit korB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Hbut_1336 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0995 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0152 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D Hbut_1337 conserved archaeal protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hbut_1445 phosphoenolpyruvate carboxykinase K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] C 00020 Citrate cycle (TCA cycle) [PATH:hbu00020] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0983 2-oxoglutarate synthase subunit korB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Hbut_0202 Succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Hbut_0203 Succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Hbut_0154 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Hbut_0157 Succinate dehydrogenase/fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Hbut_0155 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Hbut_0156 hypothetical protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Hbut_0159 L(+)-tartrate dehydratase class I, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Hbut_0158 L(+)-tartrate dehydratase beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Hbut_1445 phosphoenolpyruvate carboxykinase K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00030 Pentose phosphate pathway [PATH:hbu00030] D Hbut_1447 universally conserved protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D Hbut_1091 ribose-5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Hbut_0129 hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D Hbut_1240 predicted sugar phosphate isomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Hbut_0962 Deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D Hbut_1111 ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15] D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hbut_0498 translation initiation factor eIF-2B subunit 2 K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29] D Hbut_0662 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Hbut_1553 Aldehyde:ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] D Hbut_1001 Tungsten-containing aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] D Hbut_0351 Formaldehyde:ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] D Hbut_0737 Aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] D Hbut_0230 putative glycerate kinase (GckA) K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Hbut_0487 universally conserved uncharacterized protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] C 00040 Pentose and glucuronate interconversions D Hbut_0791 L-fuculose phosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] C 00051 Fructose and mannose metabolism [PATH:hbu00051] D Hbut_1447 universally conserved protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hbut_1423 sugar phosphate nucleotidyltransferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D Hbut_0791 L-fuculose phosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] D Hbut_0487 universally conserved uncharacterized protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Hbut_0946 Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] C 00053 Ascorbate and aldarate metabolism C 00500 Starch and sucrose metabolism [PATH:hbu00500] D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hbut_1447 universally conserved protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:hbu00520] D Hbut_0965 glucosamine-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Hbut_1036 Acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D Hbut_1420 polysaccharide biosynthesis protein K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hbut_1447 universally conserved protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D Hbut_1423 sugar phosphate nucleotidyltransferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D Hbut_1412 universally conserved protein K13010 per; perosamine synthetase [EC:2.6.1.102] C 00620 Pyruvate metabolism [PATH:hbu00620] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0983 2-oxoglutarate synthase subunit korB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0985 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hbut_1479 conserved archaeal protein K01512 acyP; acylphosphatase [EC:3.6.1.7] D Hbut_1336 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0995 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0152 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D Hbut_1337 conserved archaeal protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D Hbut_0153 Malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D Hbut_0159 L(+)-tartrate dehydratase class I, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Hbut_0158 L(+)-tartrate dehydratase beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Hbut_1445 phosphoenolpyruvate carboxykinase K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:hbu00630] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Hbut_1460 dehydrogenase K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14] D Hbut_0860 glyoxylate reductase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26] D Hbut_0505 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18] D Hbut_0503 Ribulose bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] D Hbut_1195 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hbut_1252 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hbut_0829 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0181 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Hbut_0230 putative glycerate kinase (GckA) K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Hbut_1051 Anaerobic dehydrogenases, typically selenocysteine-containing K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D Hbut_1052 Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit K00124 fdoH; formate dehydrogenase iron-sulfur subunit D Hbut_1053 Formate dehydrogenase, cytochrome b K00127 fdoI; formate dehydrogenase subunit gamma C 00640 Propanoate metabolism [PATH:hbu00640] D Hbut_1336 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0995 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0152 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D Hbut_1337 conserved archaeal protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0873 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hbut_0203 Succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Hbut_0202 Succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00650 Butanoate metabolism [PATH:hbu00650] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Hbut_0154 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Hbut_0157 Succinate dehydrogenase/fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Hbut_0155 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Hbut_0156 hypothetical protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Hbut_0873 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0983 2-oxoglutarate synthase subunit korB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Hbut_1527 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00660 C5-Branched dibasic acid metabolism D Hbut_0203 Succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Hbut_0202 Succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00562 Inositol phosphate metabolism [PATH:hbu00562] D Hbut_0794 Inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Hbut_0496 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D Hbut_0150 predicted sugar nucleotidyltransferase K07281 ipct; 1L-myo-inositol 1-phosphate cytidylyltransferase [EC:2.7.7.74] D Hbut_0151 phosphatidylglycerophosphate synthase K07291 dipps; CDP-L-myo-inositol myo-inositolphosphotransferase [EC:2.7.8.34] D Hbut_0946 Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:hbu00190] D Hbut_0182 conserved protein K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2] D Hbut_0183 NAD(P)H-quinone oxidoreductase chain K K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2] D Hbut_0185 NADH-quinone oxidoreductase chain 4 K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2] D Hbut_0188 hypothetical protein K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2] D Hbut_0191 NADH-quinone oxidoreductase chain 12 K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2] D Hbut_0190 NADH-quinone oxidoreductase chain M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2] D Hbut_0192 NADH-quinone oxidoreductase chain 14 K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] D Hbut_0189 NAD(P)H-quinone oxidoreductase chain 4L K05576 ndhE; NAD(P)H-quinone oxidoreductase subunit 4L [EC:7.1.1.2] D Hbut_0317 NADH dehydrogenase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D Hbut_0154 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Hbut_0157 Succinate dehydrogenase/fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Hbut_0155 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Hbut_0156 hypothetical protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Hbut_1202 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Hbut_1482 Cytochrome bd-type quinol oxidase, subunit 1 K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D Hbut_1483 protein with universal conserved domains K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D Hbut_0784 V-type ATP synthase alpha chain K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D Hbut_0783 V-type ATP synthase beta chain K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D Hbut_0782 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D Hbut_0785 hypothetical protein K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D Hbut_0786 V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D Hbut_0285 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D Hbut_0787 V-type ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D Hbut_0867 Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes [PATH:hbu00720] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0159 L(+)-tartrate dehydratase class I, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Hbut_0158 L(+)-tartrate dehydratase beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Hbut_0154 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Hbut_0157 Succinate dehydrogenase/fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Hbut_0155 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Hbut_0156 hypothetical protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Hbut_0202 Succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Hbut_0203 Succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Hbut_0983 2-oxoglutarate synthase subunit korB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] C 00680 Methane metabolism [PATH:hbu00680] D Hbut_1051 Anaerobic dehydrogenases, typically selenocysteine-containing K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D Hbut_1052 Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit K00124 fdoH; formate dehydrogenase iron-sulfur subunit D Hbut_1053 Formate dehydrogenase, cytochrome b K00127 fdoI; formate dehydrogenase subunit gamma D Hbut_1252 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hbut_0230 putative glycerate kinase (GckA) K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Hbut_0911 Enolase (2-phosphoglycerate dehydratase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hbut_0487 universally conserved uncharacterized protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Hbut_1240 predicted sugar phosphate isomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Hbut_0129 hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_1197 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Hbut_0391 putative phosphoserine phosphatase, SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Hbut_0224 Decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00910 Nitrogen metabolism [PATH:hbu00910] D Hbut_0861 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Hbut_1195 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hbut_0495 NADPH glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Hbut_0269 Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00920 Sulfur metabolism [PATH:hbu00920] D Hbut_1499 Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D Hbut_1364 Adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D Hbut_0658 phosphoadenosine 5'-phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D Hbut_1541 phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D Hbut_0519 Sulfide dehydrogenase flavoprotein K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D Hbut_1585 Cysteine synthase K10150 cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22] D Hbut_0113 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D Hbut_0818 Methionine gamma-lyase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:hbu00061] D Hbut_1627 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_0291 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1555 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1375 Dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:hbu00071] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism D Hbut_0230 putative glycerate kinase (GckA) K11529 gck; glycerate 2-kinase [EC:2.7.1.165] C 00564 Glycerophospholipid metabolism [PATH:hbu00564] D Hbut_0805 glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D Hbut_1566 glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] D Hbut_0005 geranylgeranylglyceryl diphosphate synthase - conserved archaeal protein K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41] D Hbut_0025 polyprenyltransferase family - UbiA K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D Hbut_1639 conserved archaeal protein K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67] D Hbut_1257 predicted Dehydrogenase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:hbu00230] D Hbut_0169 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hbut_0662 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Hbut_0299 predicted purine phosphoribosyl transferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Hbut_1076 Acid phosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Hbut_0549 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Hbut_0454 universally conserved protein K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73] D Hbut_0432 nucleoside-triphosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Hbut_0854 predicted ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Hbut_0138 ribonucleotide reductase, oxygen sensitive (RNR, class III) K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Hbut_0262 Adenylate cyclase, class 2 K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D Hbut_0381 Thymidine phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57] D Hbut_1324 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Hbut_0480 predicted nucleotide kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D Hbut_0898 universally conserved protein K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15] D Hbut_0970 universally conserved protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53] D Hbut_1364 Adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D Hbut_1499 Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D Hbut_0269 Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00240 Pyrimidine metabolism [PATH:hbu00240] D Hbut_0302 Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Hbut_0303 Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Hbut_0110 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Hbut_0109 Aspartate carbamoyltransferase regulatory chain K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D Hbut_0107 Dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D Hbut_0261 Dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D Hbut_0108 dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D Hbut_0111 Orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D Hbut_0112 Orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D Hbut_1037 Uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Hbut_0549 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Hbut_0114 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D Hbut_1327 Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Hbut_1076 Acid phosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Hbut_0092 Uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3] D Hbut_1073 S-methyl-5-thioadenosine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3] D Hbut_1012 Uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D Hbut_0381 Thymidine phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57] D Hbut_0828 Cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D Hbut_0138 ribonucleotide reductase, oxygen sensitive (RNR, class III) K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Hbut_1159 Deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D Hbut_0854 predicted ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Hbut_0397 Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Hbut_0857 Deoxycytidine deaminase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Hbut_0853 predicted alternative thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:hbu00250] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hbut_0399 L asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D Hbut_0305 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Hbut_0304 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Hbut_0110 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Hbut_0109 Aspartate carbamoyltransferase regulatory chain K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D Hbut_0873 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hbut_0495 NADPH glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Hbut_0861 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Hbut_1195 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hbut_0302 Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Hbut_0303 Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Hbut_0965 glucosamine-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C 00260 Glycine, serine and threonine metabolism [PATH:hbu00260] D Hbut_1547 hypothetical protein K00928 lysC; aspartate kinase [EC:2.7.2.4] D Hbut_0816 Homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D Hbut_0768 Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Hbut_1034 conserved archaeal protein K01733 thrC; threonine synthase [EC:4.2.3.1] D Hbut_1252 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hbut_0230 putative glycerate kinase (GckA) K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Hbut_1197 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Hbut_0391 putative phosphoserine phosphatase, SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Hbut_0829 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0181 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Hbut_1585 Cysteine synthase K10150 cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22] D Hbut_0216 Threonine dehydratase catabolic K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] C 00270 Cysteine and methionine metabolism [PATH:hbu00270] D Hbut_0113 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D Hbut_1585 Cysteine synthase K10150 cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22] D Hbut_0726 Methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Hbut_0723 Methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Hbut_0083 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Hbut_1074 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D Hbut_1182 S-adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D Hbut_0057 Spermidine synthase, SpeE K00797 speE; spermidine synthase [EC:2.5.1.16] D Hbut_0383 Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D Hbut_0022 S-methyl-5-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] D Hbut_0922 S-methyl-5-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] D Hbut_0500 ssnA; Cytosine deaminase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] D Hbut_1135 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Hbut_1132 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Hbut_1547 hypothetical protein K00928 lysC; aspartate kinase [EC:2.7.2.4] D Hbut_0818 Methionine gamma-lyase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hbut_1584 predicted transcriptional regulator K23370 serK; L-serine kinase (ADP) [EC:2.7.1.226] C 00280 Valine, leucine and isoleucine degradation [PATH:hbu00280] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0193 3-hydroxyisobutyrate dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Hbut_1527 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis D Hbut_0216 Threonine dehydratase catabolic K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] C 00300 Lysine biosynthesis [PATH:hbu00300] D Hbut_1547 hypothetical protein K00928 lysC; aspartate kinase [EC:2.7.2.4] D Hbut_1469 predicted Acetylornithine deacetylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Hbut_0126 Acetylornithine deacetylase related protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Hbut_0415 transcriptional regulator K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-] C 00310 Lysine degradation [PATH:hbu00310] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00220 Arginine biosynthesis [PATH:hbu00220] D Hbut_1203 Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D Hbut_0305 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Hbut_0304 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Hbut_1195 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hbut_0861 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Hbut_0269 Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00330 Arginine and proline metabolism [PATH:hbu00330] D Hbut_0562 uncharacterized protein, putative amidase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10] D Hbut_1623 Hydantoin utilization protein A K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14] D Hbut_1624 Hydantoin utilization protein B K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14] D Hbut_0051 Agmatinase (agmatine ureohydrolase) K01480 speB; agmatinase [EC:3.5.3.11] D Hbut_0057 Spermidine synthase, SpeE K00797 speE; spermidine synthase [EC:2.5.1.16] D Hbut_0383 Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D Hbut_1074 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D Hbut_1182 S-adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D Hbut_0328 Pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism D Hbut_0488 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00350 Tyrosine metabolism [PATH:hbu00350] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hbut_0488 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hbut_0224 Decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00360 Phenylalanine metabolism [PATH:hbu00360] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hbut_0488 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00380 Tryptophan metabolism [PATH:hbu00380] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:hbu00400] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hbut_0488 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:hbu00410] D Hbut_0224 Decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D Hbut_0873 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hbut_0343 uncharacterized protein conserved in archaea K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] C 00430 Taurine and hypotaurine metabolism C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:hbu00450] D Hbut_0818 Methionine gamma-lyase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D Hbut_0726 Methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Hbut_0723 Methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Hbut_1499 Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D Hbut_1110 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:hbu00460] D Hbut_0399 L asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D Hbut_1252 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism C 00480 Glutathione metabolism [PATH:hbu00480] D Hbut_0494 Cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Hbut_0057 Spermidine synthase, SpeE K00797 speE; spermidine synthase [EC:2.5.1.16] D Hbut_0383 Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:hbu00730] D Hbut_0289 Thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D Hbut_1459 Multidomain protein K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3] D Hbut_0566 probable thiamine biosynthesis protein, ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Hbut_0253 Thi4 family, includes putative thiamine biosynthetic enzyme K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D Hbut_0793 predicted thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D Hbut_0898 universally conserved protein K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15] D Hbut_1324 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:hbu00740] D Hbut_0557 Pyrimidine reductase, riboflavin biosynthesis, RibD K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D Hbut_0558 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D Hbut_0560 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D Hbut_0559 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9] D Hbut_0506 hypothetical protein K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161] D Hbut_0060 cytidylyl transferase, TagD K14656 ribL; FAD synthetase [EC:2.7.7.2] D Hbut_1016 predicted Nitroreductase K19286 nfrA2; FMN reductase [NAD(P)H] [EC:1.5.1.39] D Hbut_0169 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D Hbut_0043 Flavoprotein, 3-polyprenyl-4-hydroxybenzoate decarboxylase, UbiX K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:hbu00750] D Hbut_0768 Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Hbut_1034 conserved archaeal protein K01733 thrC; threonine synthase [EC:4.2.3.1] D Hbut_1032 Pyridoxine biosynthesis protein K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D Hbut_1033 predicted glutamine amidotransferase K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:hbu00760] D Hbut_0678 Archaeal DUF108 domain protein K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21] D Hbut_0680 Quinolinate synthetase A K03517 nadA; quinolinate synthase [EC:2.5.1.72] D Hbut_0679 Nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D Hbut_1124 predicted Nicotinic acid phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D Hbut_1076 Acid phosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Hbut_1560 Nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D Hbut_1211 Nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D Hbut_0932 NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D Hbut_1458 NAD-dependent protein deacetylases, SIR2 family K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D Hbut_0721 ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:hbu00770] D Hbut_1523 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D Hbut_1524 Ketopantoate reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D Hbut_1428 conserved archaeal protein K06982 pok; pantoate kinase [EC:2.7.1.169] D Hbut_0343 uncharacterized protein conserved in archaea K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D Hbut_1435 Coenzyme A biosynthesis bifunctional protein coaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D Hbut_0437 conserved uncharacterized archaeal protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237] D Hbut_0224 Decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00780 Biotin metabolism [PATH:hbu00780] D Hbut_1627 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_0291 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1555 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1375 Dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1158 predicted Biotin/lipoate A/B protein ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:hbu00785] D Hbut_0508 hypothetical protein K09711 lipS1; lipoyl synthase D Hbut_0507 Biotin synthase-related enzyme K24689 lipS2; lipoyl synthase D Hbut_0801 Lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0829 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Hbut_0181 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:hbu00790] D Hbut_0868 GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D Hbut_0178 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Hbut_0179 Organic radical activating enzyme, NrdG K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Hbut_1045 predicted PP-loop superfamily ATPase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Hbut_0015 HD superfamily metal-dependent phosphohydrolase K17487 mptB; 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase [EC:3.1.4.56] D Hbut_0951 conserved archaeal protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D Hbut_0952 predicted archaeal sugar kinase K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54] D Hbut_0276 Metal-dependent hydrolase of the beta-lactamase superfamily II K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D Hbut_1201 Molybdenum cofactor biosynthesis enzyme K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Hbut_0907 Molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Hbut_1520 predicted Molybdopterin converting factor, large subunit K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12] D Hbut_0501 Molybdenum cofactor biosynthesis bifunctional protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Hbut_0130 Molybdopterin biosynthesis protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] C 00670 One carbon pool by folate [PATH:hbu00670] D Hbut_1252 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hbut_0829 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Hbut_0853 predicted alternative thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] D Hbut_0038 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:hbu00860] D Hbut_0542 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hbut_0206 glutamyl-tRNAglu reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D Hbut_0837 glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hbut_1430 glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hbut_1386 Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Hbut_0836 Porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D Hbut_0834 Uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D Hbut_0835 Uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D Hbut_0510 Siroheme synthase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D Hbut_0037 Fe-S oxidoreductase - metallo cofactor biosynthesis protein K22226 ahbC; Fe-coproporphyrin III synthase D Hbut_0035 Fe-S oxidoreductase - arylsulfatase regulator AslB K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6] D Hbut_1202 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Hbut_0981 universally conserved protein K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Hbut_0689 Cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:hbu00130] D Hbut_1488 4-hydroxybenzoate polyprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D Hbut_1450 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98] D Hbut_0043 Flavoprotein, 3-polyprenyl-4-hydroxybenzoate decarboxylase, UbiX K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D Hbut_0042 predicted ubiquinone/menaquinone biosynthesis methyl transferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D Hbut_1335 predicted 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:hbu00900] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Hbut_1527 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Hbut_1531 3-hydroxy-3-methylglutaryl-coenzyme A reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] D Hbut_0877 Mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D Hbut_0538 predicted archaeal kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26] D Hbut_1634 universally conserved protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182] D Hbut_1633 universally conserved protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182] D Hbut_1635 predicted 3-octaprenyl-4-hydroxybenzoate carboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126] D Hbut_0043 Flavoprotein, 3-polyprenyl-4-hydroxybenzoate decarboxylase, UbiX K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D Hbut_0539 Isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D Hbut_0540 Geranylgeranyl pyrophosphate synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Hbut_1087 Undecaprenyl pyrophosphate synthetase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis D Hbut_0964 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Hbut_1036 Acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:hbu00261] D Hbut_1499 Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D Hbut_1547 hypothetical protein K00928 lysC; aspartate kinase [EC:2.7.2.4] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:hbu00521] D Hbut_1078 phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hbut_0496 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D Hbut_0794 Inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Hbut_0964 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Hbut_1036 Acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis D Hbut_0964 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Hbut_1036 Acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 00401 Novobiocin biosynthesis [PATH:hbu00401] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hbut_0488 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis C 00333 Prodigiosin biosynthesis D Hbut_1627 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_0291 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1555 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1375 Dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites D Hbut_0083 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:hbu00627] D Hbut_1479 conserved archaeal protein K01512 acyP; acylphosphatase [EC:3.6.1.7] D Hbut_0043 Flavoprotein, 3-polyprenyl-4-hydroxybenzoate decarboxylase, UbiX K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation [PATH:hbu00633] D Hbut_1368 Periplasmic hydrogenase large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6] D Hbut_1371 NiFe hydrogenase K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6] D Hbut_0669 pyruvate synthase subunit porA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0730 Ketoisovalerate oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Hbut_0670 pyruvate synthase subunit porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0729 pyruvate synthase subunit, porB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Hbut_0732 pyruvate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0667 pyruvate/ketoisovalerate oxidoreductase gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Hbut_0731 Ketoisovalerate oxidoreductase subunit vorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Hbut_0668 pyruvate synthase subunit porD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:hbu03020] D Hbut_1573 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D Hbut_1574 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D Hbut_1575 DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D Hbut_0530 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D Hbut_1648 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D Hbut_0439 DNA-directed RNA polymerase subunit E'' K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D Hbut_0467 hypothetical protein K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6] D Hbut_1572 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D Hbut_0534 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D Hbut_0052 DNA-directed RNA polymerase, subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D Hbut_0917 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 C 03022 Basal transcription factors [PATH:hbu03022] D Hbut_0054 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Hbut_0458 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Hbut_0934 TATA-box binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Hbut_1136 predicted transcription initiation factor IIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D Hbut_0064 XPD/Rad3 related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:hbu03010] D Hbut_0535 30S ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2 D Hbut_1306 30S ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3 D Hbut_0528 30S ribosomal protein S4p K02986 RP-S4; small subunit ribosomal protein S4 D Hbut_1320 50S ribosomal protein S5p K02988 RP-S5; small subunit ribosomal protein S5 D Hbut_1580 30S ribosomal protein S7p K02992 RP-S7; small subunit ribosomal protein S7 D Hbut_1315 30S ribosomal protein S8p K02994 RP-S8; small subunit ribosomal protein S8 D Hbut_0533 30S ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D Hbut_1582 30S ribosomal protein S10p K02946 RP-S10; small subunit ribosomal protein S10 D Hbut_0529 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Hbut_1578 30S ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12 D Hbut_0527 30S ribosomal protein S13p K02952 RP-S13; small subunit ribosomal protein S13 D Hbut_1314 30S ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D Hbut_0431 30S ribosomal protein S13e K02956 RP-S15; small subunit ribosomal protein S15 D Hbut_1309 30S ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D Hbut_1294 30S ribosomal protein S19p K02965 RP-S19; small subunit ribosomal protein S19 D Hbut_0428 30S ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D Hbut_1312 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D Hbut_0442 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D Hbut_0453 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D Hbut_0482 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D Hbut_1595 30S ribosomal protein S19E K02966 RP-S19e; small subunit ribosomal protein S19e D Hbut_0436 30S ribosomal protein S24E K02974 RP-S24e; small subunit ribosomal protein S24e D Hbut_1104 30S ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e D Hbut_0776 30S ribosomal protein S26 K02976 RP-S26e; small subunit ribosomal protein S26e D Hbut_1641 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D Hbut_0435 30S ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Hbut_0546 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D Hbut_0929 30S ribosomal protein S3e K02983 RP-S30e; small subunit ribosomal protein S30e D Hbut_1606 50S ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1 D Hbut_1293 50S ribosomal protein L2p K02886 RP-L2; large subunit ribosomal protein L2 D Hbut_1302 50S ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3 D Hbut_1313 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Hbut_1316 50S ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D Hbut_1605 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Hbut_0400 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12 D Hbut_0532 50S ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13 D Hbut_1310 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Hbut_1322 50S ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D Hbut_1319 50S ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18 D Hbut_1305 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Hbut_1304 50S ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23 D Hbut_1311 50S ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24 D Hbut_1307 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Hbut_1321 50S ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D Hbut_1303 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D Hbut_0543 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Hbut_1653 50S ribosomal protein L10e K02866 RP-L10e; large subunit ribosomal protein L10e D Hbut_0099 50S ribosomal protein L13e K02873 RP-L13e; large subunit ribosomal protein L13e D Hbut_1328 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D Hbut_0553 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D Hbut_0531 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D Hbut_1318 50S ribosomal protein L19E K02885 RP-L19e; large subunit ribosomal protein L19e D Hbut_1660 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D Hbut_0547 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D Hbut_1576 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D Hbut_1598 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D Hbut_1317 50S ribosomal protein L32E K02912 RP-L32e; large subunit ribosomal protein L32e D Hbut_1326 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D Hbut_0874 50S ribosomal protein L35Ae K02917 RP-L35Ae; large subunit ribosomal protein L35Ae D Hbut_1571 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D Hbut_0573 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D Hbut_0464 50S ribosomal protein L38E K02923 RP-L38e; large subunit ribosomal protein L38e D Hbut_1597 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D Hbut_0579 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Hbut_1642 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D Hbut_1600 50S ribosomal protein LX K02944 RP-LX; large subunit ribosomal protein LX D Hbut_1672 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hbut_1671 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hbut_0653 SRSR cluster K01980 23SrRNA; 23S ribosomal RNA D Hbut_0717 SRSR cluster K01980 23SrRNA; 23S ribosomal RNA D Hbut_0882 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:hbu00970] D Hbut_0623 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hbut_0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hbut_1049 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hbut_1609 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1273 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1163 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1176 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1009 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1127 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Hbut_1664 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Hbut_0086 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Hbut_1617 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Hbut_0833 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Hbut_1590 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hbut_0143 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hbut_0387 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hbut_0525 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hbut_0139 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hbut_0003 tRNA-His K14226 tRNA-His; tRNA His D Hbut_1023 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Hbut_0011 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_0385 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_1629 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_0379 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_1351 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_1017 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Hbut_1489 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Hbut_1616 tRNA-Met K14230 tRNA-Met; tRNA Met D Hbut_1129 tRNA-Met K14230 tRNA-Met; tRNA Met D Hbut_1118 tRNA-Met K14230 tRNA-Met; tRNA Met D Hbut_0526 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Hbut_1619 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hbut_1160 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hbut_0384 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_1331 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_1583 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_0477 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_1114 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hbut_0058 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hbut_0461 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hbut_1131 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Hbut_0465 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Hbut_0473 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_0369 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_0135 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_0074 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_0542 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hbut_0832 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Hbut_1120 glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Hbut_0928 glutamyl-tRNA(Gln) amidotransferase subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] D Hbut_0927 glutamyl-tRNA(Gln) amidotransferase subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] D Hbut_1607 Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Hbut_0034 Aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Hbut_0050 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Hbut_0966 Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Hbut_1249 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Hbut_1188 Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Hbut_1110 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Hbut_0879 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Hbut_1241 Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hbut_1425 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Hbut_0055 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Hbut_1178 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hbut_0779 Bifunctional aminoacyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Hbut_0954 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Hbut_0887 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Hbut_0888 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Hbut_0889 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hbut_0947 Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:hbu03060] D Hbut_1323 Preprotein translocase subunit secY K03076 secY; preprotein translocase subunit SecY D Hbut_1662 Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Hbut_1388 7S ribosomal RNA K01983 ffs; SRP RNA D Hbut_1602 Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor D Hbut_1603 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Hbut_0106 Signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19 D Hbut_0265 Oxyanion-translocating ATPase, ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_0806 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_0807 hypothetical protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_1509 mttA/Hcf106 K03116 tatA; sec-independent protein translocase protein TatA D Hbut_0264 Sec-independent secretion pathway protein K03116 tatA; sec-independent protein translocase protein TatA D Hbut_1508 predicted Sec-independent protein secretion pathway component TatC K03118 tatC; sec-independent protein translocase protein TatC D Hbut_0915 predicted signal peptide K13280 SEC11; signal peptidase I [EC:3.4.21.89] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:hbu04122] D Hbut_1201 Molybdenum cofactor biosynthesis enzyme K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Hbut_0133 Molybdopterin converting factor, small subunit K03636 moaD; sulfur-carrier protein D Hbut_1015 conserved archaeal protein K03636 moaD; sulfur-carrier protein D Hbut_1093 predicted sulphor transporting protein K03636 moaD; sulfur-carrier protein D Hbut_1520 predicted Molybdopterin converting factor, large subunit K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12] D Hbut_0907 Molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Hbut_0501 Molybdenum cofactor biosynthesis bifunctional protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Hbut_0566 probable thiamine biosynthesis protein, ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Hbut_0093 conserved archaeal protein K03154 thiS; sulfur carrier protein D Hbut_0592 hypothetical protein K03154 thiS; sulfur carrier protein C 03050 Proteasome [PATH:hbu03050] D Hbut_1140 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit D Hbut_0568 proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Hbut_1564 proteasome beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Hbut_1567 proteasome beta precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03018 RNA degradation [PATH:hbu03018] D Hbut_1650 conserved archaeal protein K07573 CSL4; exosome complex component CSL4 D Hbut_0570 predicted RNA binding protein Rrp4 K03679 RRP4; exosome complex component RRP4 D Hbut_0572 RNase PH-related exoribonuclease K12589 RRP42; exosome complex component RRP42 D Hbut_0571 ribonuclease PH K11600 RRP41; exosome complex component RRP41 D Hbut_0911 Enolase (2-phosphoglycerate dehydratase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] B B 09124 Replication and repair C 03030 DNA replication [PATH:hbu03030] D Hbut_0890 conserved archaeal protein K02316 dnaG; DNA primase [EC:2.7.7.101] D Hbut_0844 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Hbut_0896 DNA polymerase III K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Hbut_1274 DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Hbut_0903 minichromosome maintenance complex K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Hbut_1644 probable DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D Hbut_1102 conserved archaeal protein K18882 priL; DNA primase large subunit D Hbut_0018 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1645 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen D Hbut_1286 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_0906 Replication factor C large subunit K04800 rfcL; replication factor C large subunit D Hbut_1366 Endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Hbut_0421 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03410 Base excision repair [PATH:hbu03410] D Hbut_0585 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D Hbut_0266 predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Hbut_0018 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1645 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen D Hbut_1286 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1366 Endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Hbut_0421 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Hbut_0091 predicted Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Hbut_1039 predicted Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] C 03420 Nucleotide excision repair [PATH:hbu03420] D Hbut_0917 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 D Hbut_0064 XPD/Rad3 related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] D Hbut_0841 predicted ERCC4-type nuclease K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D Hbut_0449 ERCC4-type nuclease K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D Hbut_0018 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1645 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen D Hbut_1286 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_0421 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03430 Mismatch repair [PATH:hbu03430] D Hbut_0018 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1645 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen D Hbut_1286 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_0421 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03440 Homologous recombination C 03450 Non-homologous end-joining D Hbut_1366 Endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 D Hbut_0438 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D Hbut_1604 transcription antiterminator K15172 SUPT5H; transcription elongation factor SPT5 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:hbu02010] D Hbut_0335 ABC-type tungstate transport system, permease component, TupB K05772 tupA; tungstate transport system substrate-binding protein D Hbut_0334 ABC-type tungstate transport system, periplasmic component, TupA K05773 tupB; tungstate transport system permease protein D Hbut_0333 predicted ABC transporter K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6] D Hbut_0375 ABC-type molybdate transport system, periplasmic component, ModA K02020 modA; molybdate transport system substrate-binding protein D Hbut_0376 ABC-type molybdate transport system, permease component, ModB K02018 modB; molybdate transport system permease protein D Hbut_0377 ABC (ATP-binding cassette) transporter domain K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Hbut_0067 ABC-type Fe3+ transport system, periplasmic component K02012 afuA; iron(III) transport system substrate-binding protein D Hbut_0406 ABC-type Fe3+ transport permease, ThiP K02011 afuB; iron(III) transport system permease protein D Hbut_0066 ABC-type Fe3+ transport - permease K02011 afuB; iron(III) transport system permease protein D Hbut_0065 ABC-type, ATP binding, spermidine/spermine transporter, PotA K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D Hbut_0326 Thiamine-binding, periplasmic protein K02064 thiB; thiamine transport system substrate-binding protein D Hbut_0325 ABC-type iron(III) transport system, permease component K02063 thiP; thiamine transport system permease protein D Hbut_0308 Maltose/maltodextrin import ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Hbut_0812 predicted ABC transporter K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Hbut_1418 predicted ABC transporter K07335 bmpA; basic membrane protein A and related proteins D Hbut_0298 uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Hbut_1416 predicted ABC transporter K23535 nupB; general nucleoside transport system permease protein D Hbut_0097 ABC-type uncharacterized transport, permease K23535 nupB; general nucleoside transport system permease protein D Hbut_1415 predicted ABC transporter K23536 nupC; general nucleoside transport system permease protein D Hbut_0096 ABC-transporter, permease component K23536 nupC; general nucleoside transport system permease protein D Hbut_0098 ribose ABC transporter ATP-binding protein, RbsA-1 K23537 nupA; general nucleoside transport system ATP-binding protein D Hbut_1417 predicted ABC transporter K23537 nupA; general nucleoside transport system ATP-binding protein D Hbut_1463 predicted transporter K17237 inoE; inositol-phosphate transport system substrate-binding protein D Hbut_1464 ABC-type sugar transport system K17238 inoF; inositol-phosphate transport system permease protein D Hbut_1465 ABC-type sugar transport system K17239 inoG; inositol-phosphate transport system permease protein D Hbut_1466 Maltose/maltodextrin import ATP-binding protein K17240 inoK; inositol-phosphate transport system ATP-binding protein D Hbut_0634 ABC-type phosphate transport, periplasmic protein K02040 pstS; phosphate transport system substrate-binding protein D Hbut_0635 ABC-type phosphate transport, permease K02037 pstC; phosphate transport system permease protein D Hbut_0636 ABC-type phosphate transport, permease K02038 pstA; phosphate transport system permease protein D Hbut_0637 phosphate import ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Hbut_0616 ABC-type branched-chain amino acid transport, periplasmic component K01999 livK; branched-chain amino acid transport system substrate-binding protein D Hbut_0614 High-affinity branched-chain amino acid transport ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D Hbut_0613 High-affinity branched-chain amino acid transport ATP-binding protein F K01996 livF; branched-chain amino acid transport system ATP-binding protein D Hbut_0241 hypothetical protein K02009 cbiN; cobalt/nickel transport protein D Hbut_0242 ABC-type Co2+ transport, permease (CbiM) K02007 cbiM; cobalt/nickel transport system permease protein D Hbut_0240 putative cobalt transport protein K02008 cbiQ; cobalt/nickel transport system permease protein D Hbut_0239 ABC-type cobalt transport system, ATPase (CbiO) K02006 cbiO; cobalt/nickel transport system ATP-binding protein D Hbut_0231 ABC transporter, ATP binding K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Hbut_1512 predicted ABC transporter K02195 ccmC; heme exporter protein C C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:hbu03070] D Hbut_1323 Preprotein translocase subunit secY K03076 secY; preprotein translocase subunit SecY D Hbut_1602 Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor D Hbut_1662 Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Hbut_1509 mttA/Hcf106 K03116 tatA; sec-independent protein translocase protein TatA D Hbut_0264 Sec-independent secretion pathway protein K03116 tatA; sec-independent protein translocase protein TatA D Hbut_1508 predicted Sec-independent protein secretion pathway component TatC K03118 tatC; sec-independent protein translocase protein TatC B B 09132 Signal transduction C 02020 Two-component system [PATH:hbu02020] D Hbut_0634 ABC-type phosphate transport, periplasmic protein K02040 pstS; phosphate transport system substrate-binding protein D Hbut_0153 Malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D Hbut_1195 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Hbut_1371 NiFe hydrogenase K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6] D Hbut_1368 Periplasmic hydrogenase large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6] D Hbut_1482 Cytochrome bd-type quinol oxidase, subunit 1 K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D Hbut_1483 protein with universal conserved domains K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D Hbut_1420 polysaccharide biosynthesis protein K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:hbu02024] D Hbut_0616 ABC-type branched-chain amino acid transport, periplasmic component K01999 livK; branched-chain amino acid transport system substrate-binding protein D Hbut_0614 High-affinity branched-chain amino acid transport ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D Hbut_0613 High-affinity branched-chain amino acid transport ATP-binding protein F K01996 livF; branched-chain amino acid transport system ATP-binding protein D Hbut_0824 conserved archaeal protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Hbut_0609 ABC-type dipeptide transport, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Hbut_0608 ABC-type dipeptide/oligopeptide transport system, permease K02033 ABC.PE.P; peptide/nickel transport system permease protein D Hbut_0607 ABC-type dipeptide/oligopeptide/nickel transport system, permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Hbut_0606 Oligopeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Hbut_1535 Oligopeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Hbut_0605 Oligopeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D Hbut_0822 oppF; Oligopeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D Hbut_1323 Preprotein translocase subunit secY K03076 secY; preprotein translocase subunit SecY D Hbut_1602 Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor D Hbut_1662 Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Hbut_0911 Enolase (2-phosphoglycerate dehydratase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism D Hbut_0981 universally conserved protein K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Hbut_0689 Cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance C 01502 Vancomycin resistance [PATH:hbu01502] D Hbut_1419 conserved crenarchaeal protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:hbu01000] C 01001 Protein kinases [BR:hbu01001] D Hbut_0433 predicted serine/threonine kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D Hbut_1404 putative kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D Hbut_0072 RIO-like serine/threonine kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] C 01009 Protein phosphatases and associated proteins [BR:hbu01009] D Hbut_1086 translation initiation factor 2, beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2 D Hbut_1132 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Hbut_0391 putative phosphoserine phosphatase, SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:hbu01002] D Hbut_0969 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Hbut_1372 universally conserved protein K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-] D Hbut_1614 Pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D Hbut_0965 glucosamine-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Hbut_0996 protease I K26818 pfpI; archaeal arginyl aminopeptidase [EC:3.4.11.27] D Hbut_1334 hypothetical protein K07052 K07052; CAAX protease family protein D Hbut_0494 Cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Hbut_1469 predicted Acetylornithine deacetylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Hbut_0126 Acetylornithine deacetylase related protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Hbut_0885 Methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Hbut_0451 Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D Hbut_0621 Leucyl aminopeptidase, AmpS K19689 ampS; aminopeptidase [EC:3.4.11.-] D Hbut_0166 carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19] D Hbut_0773 predicted peptidase K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Hbut_0618 predicted Zn-dependent protease K06974 amzA; archaemetzincin [EC:3.4.-.-] D Hbut_1384 D-aminopeptidase K16203 dppA1; D-amino peptidase [EC:3.4.11.-] D Hbut_0915 predicted signal peptide K13280 SEC11; signal peptidase I [EC:3.4.21.89] D Hbut_0411 uncharacterized membrane protein K07059 K07059; rhomboid family protein D Hbut_0568 proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Hbut_1564 proteasome beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Hbut_1567 proteasome beta precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Hbut_0399 L asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D Hbut_0409 predicted Zn-dependent protease, TldD K03592 pmbA; PmbA protein D Hbut_0410 predicted Zn-dependent protease, TldD K03568 tldD; TldD protein C 01003 Glycosyltransferases [BR:hbu01003] D Hbut_1432 UDP-N-acetylmuramyl pentapeptide phosphotransferase K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15] D Hbut_1205 universally conserved protein K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18] C 01005 Lipopolysaccharide biosynthesis proteins [BR:hbu01005] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:hbu01011] D Hbut_1419 conserved crenarchaeal protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01004 Lipid biosynthesis proteins [BR:hbu01004] D Hbut_1627 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_0291 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1555 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1375 Dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hbut_1336 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0995 universally conserved protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D Hbut_0152 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D Hbut_1337 conserved archaeal protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:hbu01006] D Hbut_0540 Geranylgeranyl pyrophosphate synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Hbut_1335 predicted 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D Hbut_1488 4-hydroxybenzoate polyprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D Hbut_1202 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:hbu01007] D Hbut_0055 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Hbut_0542 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hbut_0889 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hbut_0947 Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Hbut_1188 Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Hbut_1178 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hbut_1110 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Hbut_1425 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Hbut_0879 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Hbut_1241 Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hbut_0034 Aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Hbut_0954 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Hbut_0050 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Hbut_1249 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Hbut_0779 Bifunctional aminoacyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Hbut_0966 Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Hbut_1607 Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Hbut_0887 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Hbut_0888 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Hbut_1044 Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hbut_0488 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hbut_0873 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hbut_0837 glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hbut_1430 glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hbut_1412 universally conserved protein K13010 per; perosamine synthetase [EC:2.6.1.102] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:hbu03000] D Hbut_1135 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Hbut_0934 TATA-box binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Hbut_1340 HTH-type transcriptional regulator lysM K06154 lysM; Lrp/AsnC family transcriptional regulator, involved in the regulation of lysine biosynthesis D Hbut_0125 predicted transcriptional regulator - conserved protein K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator D Hbut_0163 predicted Iron dependent repressor K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Hbut_1158 predicted Biotin/lipoate A/B protein ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Hbut_0374 uncharacterized conserved archaeal protein K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator D Hbut_0646 hypothetical protein K07725 csa3; CRISPR-associated protein Csa3 D Hbut_0657 hypothetical protein K07725 csa3; CRISPR-associated protein Csa3 D Hbut_0033 transcriptional regulator, HTH-type - conserved archaeal protein K07728 K07728; putative transcriptional regulator D Hbut_0476 transcriptional regulator K07731 K07731; putative transcriptional regulator D Hbut_0204 Nickel responsive regulator K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D Hbut_0366 predicted transcriptional regulator, NikR K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D Hbut_0316 putative nickel responsive regulator K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D Hbut_1485 conserved crenarchaeal protein K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator C 03021 Transcription machinery [BR:hbu03021] D Hbut_0917 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 D Hbut_0054 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Hbut_0458 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Hbut_0934 TATA-box binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Hbut_1136 predicted transcription initiation factor IIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D Hbut_0064 XPD/Rad3 related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] D Hbut_0438 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D Hbut_1604 transcription antiterminator K15172 SUPT5H; transcription elongation factor SPT5 D Hbut_1433 conserved hypothetical ATP binding protein K24104 GPN; GPN-loop GTPase D Hbut_0122 predicted ATP binding protein K24104 GPN; GPN-loop GTPase D Hbut_1577 nusA; putative transcription elongation factor K02600 nusA; transcription termination/antitermination protein NusA D Hbut_1574 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D Hbut_1575 DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D Hbut_1573 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D Hbut_0530 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D Hbut_0439 DNA-directed RNA polymerase subunit E'' K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D Hbut_0467 hypothetical protein K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6] D Hbut_1572 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D Hbut_1648 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D Hbut_0534 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D Hbut_0052 DNA-directed RNA polymerase, subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D Hbut_1646 DNA-directed RNA polymerase subunit M K03057 tfs; transcription factor S D Hbut_0380 RNA polymerase, subunit M K03057 tfs; transcription factor S C 03019 Messenger RNA biogenesis [BR:hbu03019] D Hbut_0438 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D Hbut_1604 transcription antiterminator K15172 SUPT5H; transcription elongation factor SPT5 D Hbut_0300 ATPases of AAA+ class, SpoVK, putative cell division K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_1358 ATP-dependent protease K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_0894 predicted RNA-binding protein K06965 PELO; protein pelota D Hbut_1221 Peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1 D Hbut_1581 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D Hbut_1650 conserved archaeal protein K07573 CSL4; exosome complex component CSL4 D Hbut_0570 predicted RNA binding protein Rrp4 K03679 RRP4; exosome complex component RRP4 D Hbut_0571 ribonuclease PH K11600 RRP41; exosome complex component RRP41 D Hbut_0572 RNase PH-related exoribonuclease K12589 RRP42; exosome complex component RRP42 D Hbut_0911 Enolase (2-phosphoglycerate dehydratase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 03041 Spliceosome C 03011 Ribosome [BR:hbu03011] D Hbut_0428 30S ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D Hbut_1312 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D Hbut_0442 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D Hbut_0453 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D Hbut_0482 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D Hbut_1595 30S ribosomal protein S19E K02966 RP-S19e; small subunit ribosomal protein S19e D Hbut_0436 30S ribosomal protein S24E K02974 RP-S24e; small subunit ribosomal protein S24e D Hbut_1104 30S ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e D Hbut_0776 30S ribosomal protein S26 K02976 RP-S26e; small subunit ribosomal protein S26e D Hbut_1641 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D Hbut_0435 30S ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Hbut_0546 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D Hbut_0929 30S ribosomal protein S3e K02983 RP-S30e; small subunit ribosomal protein S30e D Hbut_1303 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D Hbut_0543 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Hbut_1653 50S ribosomal protein L10e K02866 RP-L10e; large subunit ribosomal protein L10e D Hbut_0099 50S ribosomal protein L13e K02873 RP-L13e; large subunit ribosomal protein L13e D Hbut_1328 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D Hbut_0553 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D Hbut_0531 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D Hbut_1318 50S ribosomal protein L19E K02885 RP-L19e; large subunit ribosomal protein L19e D Hbut_1660 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D Hbut_0547 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D Hbut_1576 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D Hbut_1598 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D Hbut_1317 50S ribosomal protein L32E K02912 RP-L32e; large subunit ribosomal protein L32e D Hbut_1326 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D Hbut_0874 50S ribosomal protein L35Ae K02917 RP-L35Ae; large subunit ribosomal protein L35Ae D Hbut_1571 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D Hbut_0573 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D Hbut_0464 50S ribosomal protein L38E K02923 RP-L38e; large subunit ribosomal protein L38e D Hbut_1597 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D Hbut_0579 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Hbut_1642 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D Hbut_0535 30S ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2 D Hbut_1306 30S ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3 D Hbut_0528 30S ribosomal protein S4p K02986 RP-S4; small subunit ribosomal protein S4 D Hbut_1320 50S ribosomal protein S5p K02988 RP-S5; small subunit ribosomal protein S5 D Hbut_1580 30S ribosomal protein S7p K02992 RP-S7; small subunit ribosomal protein S7 D Hbut_1315 30S ribosomal protein S8p K02994 RP-S8; small subunit ribosomal protein S8 D Hbut_0533 30S ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D Hbut_1582 30S ribosomal protein S10p K02946 RP-S10; small subunit ribosomal protein S10 D Hbut_0529 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Hbut_1578 30S ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12 D Hbut_0527 30S ribosomal protein S13p K02952 RP-S13; small subunit ribosomal protein S13 D Hbut_1314 30S ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D Hbut_0431 30S ribosomal protein S13e K02956 RP-S15; small subunit ribosomal protein S15 D Hbut_1309 30S ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D Hbut_1294 30S ribosomal protein S19p K02965 RP-S19; small subunit ribosomal protein S19 D Hbut_1606 50S ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1 D Hbut_1293 50S ribosomal protein L2p K02886 RP-L2; large subunit ribosomal protein L2 D Hbut_1302 50S ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3 D Hbut_1313 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Hbut_1316 50S ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D Hbut_1605 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Hbut_0532 50S ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13 D Hbut_1310 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Hbut_1322 50S ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D Hbut_1319 50S ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18 D Hbut_1305 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Hbut_1304 50S ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23 D Hbut_1311 50S ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24 D Hbut_1307 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Hbut_1321 50S ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D Hbut_0400 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12 D Hbut_1600 50S ribosomal protein LX K02944 RP-LX; large subunit ribosomal protein LX D Hbut_0882 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Hbut_1672 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hbut_1671 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hbut_0653 SRSR cluster K01980 23SrRNA; 23S ribosomal RNA D Hbut_0717 SRSR cluster K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:hbu03009] D Hbut_0030 ribosomal biogenesis protein - Nop56/SIK1 K14564 NOP56; nucleolar protein 56 D Hbut_1329 predicted pseudouridine synthase K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] D Hbut_0574 conserved archaeal protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4 D Hbut_0319 conserved uncharacterized protein, Mra1 K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260] D Hbut_1592 conserved archaeal protein K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260] D Hbut_1405 universally conserved protein K06961 KRR1; ribosomal RNA assembly protein D Hbut_1404 putative kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D Hbut_0072 RIO-like serine/threonine kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] D Hbut_0480 predicted nucleotide kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D Hbut_0010 conserved archaeal protein-possible RNAse P component K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157] D Hbut_0485 RNase L inhibitor, ATPase K06174 ABCE1; ATP-binding cassette, sub-family E, member 1 D Hbut_1562 predicted GTPase K06943 NOG1; nucleolar GTP-binding protein D Hbut_1308 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Hbut_0556 RNase P, Rpp14 family K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Hbut_0555 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Hbut_1636 conserved archaeal protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-] D Hbut_0131 GTPase or GTP-binding - conserved crenarchaeal protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-] D Hbut_1599 translation initiation factor 6 (eIF-6) K03264 EIF6; translation initiation factor 6 D Hbut_1064 predicted nonsense mRNA decay protein K07562 NMD3; 60S ribosomal export protein NMD3 D Hbut_1236 predicted nonsense mediated mRNA decay K07562 NMD3; 60S ribosomal export protein NMD3 D Hbut_0569 universally conserved uncharacterized protein family UPF0023 K14574 SDO1; ribosome maturation protein SDO1 D Hbut_0300 ATPases of AAA+ class, SpoVK, putative cell division K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_1358 ATP-dependent protease K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_1558 conserved archaeal protein K07565 NIP7; 60S ribosome subunit biogenesis protein NIP7 D Hbut_0031 rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein D Hbut_0543 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Hbut_0457 RNA binding protein, Gar1-type K07569 gar1; RNA-binding protein D Hbut_1577 nusA; putative transcription elongation factor K02600 nusA; transcription termination/antitermination protein NusA D Hbut_1657 Dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Hbut_0843 ribosomal RNA small subunit methyltransferase B K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Hbut_0396 tRNA and rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Hbut_0455 Methyltransferase B - rRNA small subunit K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Hbut_0762 ribosomal RNA small subunit methyltransferase B K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Hbut_0511 tRNA and rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Hbut_1330 predicted Methyltransferase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D Hbut_0583 universally conserved protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D Hbut_0984 predicted Acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D Hbut_0895 predicted acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D Hbut_0019 glutathione synthase-RimK/ribosomal protein S6 modification (glutaminyl transferase) K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-] D Hbut_1138 GTPase K03665 hflX; GTPase D Hbut_0770 universally conserved protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Hbut_1594 conserved archaeal protein K07574 yhbY; RNA-binding protein D Hbut_0550 predicted GTPase, probable translation factor K06942 ychF; ribosome-binding ATPase D Hbut_1628 conserved archaeal protein K22469 fau-1; probable ribonuclease FAU-1 [EC:3.1.26.-] C 03016 Transfer RNA biogenesis [BR:hbu03016] D Hbut_1308 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Hbut_0556 RNase P, Rpp14 family K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Hbut_0555 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Hbut_1593 conserved archaeal protein K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5] D Hbut_0661 Metal-dependent hydrolase of beta lactamase, ElaC K00784 rnz; ribonuclease Z [EC:3.1.26.11] D Hbut_0518 universally conserved protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D Hbut_0516 uncharacterized conserved protein K24956 ZBTB8OS; protein archease D Hbut_1581 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D Hbut_0542 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hbut_0779 Bifunctional aminoacyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Hbut_1425 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Hbut_1241 Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hbut_1110 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Hbut_1178 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hbut_1607 Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Hbut_0050 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Hbut_0966 Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Hbut_1249 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Hbut_1188 Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Hbut_0879 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Hbut_0954 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Hbut_0887 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Hbut_0888 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Hbut_0889 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hbut_0947 Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Hbut_0781 universally conserved protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D Hbut_1214 predicted metal-dependent hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-] D Hbut_0648 Metal-dependent hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-] D Hbut_1092 conserved archaeal protein K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] D Hbut_0460 N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] D Hbut_0720 Methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Hbut_0088 methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Hbut_1352 tRNA methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220] D Hbut_0736 universally conserved protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-] D Hbut_1116 conserved archaeal protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] D Hbut_0026 conserved archaeal protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] D Hbut_1144 conserved archaeal protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] D Hbut_0628 putative tRNA pseudouridine synthase D, TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D Hbut_1661 predicted pseudouridylate synthase K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25] D Hbut_0433 predicted serine/threonine kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D Hbut_0434 Metal-dependent protease, possible chaperone activity, QR17 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] D Hbut_0770 universally conserved protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Hbut_0427 RNA binding protein, THUMP domain K06963 TAN1; tRNA acetyltransferase TAN1 D Hbut_1190 hypothetical protein K06963 TAN1; tRNA acetyltransferase TAN1 D Hbut_1548 universally conserved protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5] D Hbut_0014 tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72] D Hbut_0045 General archaeal splicing enzyme K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D Hbut_0955 hypothetical protein K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D Hbut_0388 2'-5' RNA ligase, Lig T K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D Hbut_1373 RNA:NAD 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-] D Hbut_0055 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Hbut_0034 Aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Hbut_1655 rRNA methylase K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200] D Hbut_0870 hypothetical protein K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D Hbut_0777 hypothetical protein K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257] D Hbut_1559 predicted tRNA and rRNA cytosine-C5-methylase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-] D Hbut_0079 conserved archaeal protein K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221] D Hbut_1654 conserved archaeal protein K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256] D Hbut_0330 predicted DNA modification methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213] D Hbut_1137 conserved archaeal protein K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206] D Hbut_0094 predicted ATPase of the PP-loop superfamily K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15] D Hbut_0591 predicted ATPase of the PP-loop superfamily K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15] D Hbut_1045 predicted PP-loop superfamily ATPase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Hbut_0178 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Hbut_0179 Organic radical activating enzyme, NrdG K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Hbut_0469 Queuine/archaeosine tRNA-ribosyltransferase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48] D Hbut_0566 probable thiamine biosynthesis protein, ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Hbut_0008 nucleic acid binding protein with Zn ribbon domain - conserved archaeal protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22] D Hbut_0953 predicted P-loop ATPase fused to an acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193] D Hbut_0612 predicted P-loop ATPase fused to an acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193] D Hbut_1153 P-loop ATPase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193] C 03012 Translation factors [BR:hbu03012] D Hbut_1399 eIF-1A; translation initiation factor 1A K03236 EIF1A; translation initiation factor 1A D Hbut_0053 translation initiation factor eIF-1/SUI1 K03113 EIF1; translation initiation factor 1 D Hbut_1640 translation initiation factor 2 alpha K03237 EIF2S1; translation initiation factor 2 subunit 1 D Hbut_1086 translation initiation factor 2, beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2 D Hbut_0441 translation initiation factor 2 gamma subunit K03242 EIF2S3; translation initiation factor 2 subunit 3 D Hbut_0499 putative translation initiation factor eIF-2B subunit 2 K03680 EIF2B4; translation initiation factor eIF-2B subunit delta D Hbut_1663 translation initiation factor 5A K03263 EIF5A; translation initiation factor 5A D Hbut_0443 translation initiation factor 2 K03243 EIF5B; translation initiation factor 5B D Hbut_1599 translation initiation factor 6 (eIF-6) K03264 EIF6; translation initiation factor 6 D Hbut_1581 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D Hbut_1357 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta D Hbut_0840 elongation factor 2 K03234 EEF2; elongation factor 2 D Hbut_1652 conserved archaeal protein K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] D Hbut_1070 universally conserved protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14] D Hbut_1221 Peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1 D Hbut_1656 conserved archaeal protein K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Hbut_0765 Peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] C 03110 Chaperones and folding catalysts [BR:hbu03110] D Hbut_0918 Thermosome alpha subunit K22447 cct; archaeal chaperonin D Hbut_0481 Thermosome beta subunit K22447 cct; archaeal chaperonin D Hbut_1258 predicted small heat shock protein K13993 HSP20; HSP20 family protein D Hbut_1081 hypothetical protein K13993 HSP20; HSP20 family protein D Hbut_1601 hypothetical protein K04797 pfdA; prefoldin alpha subunit D Hbut_0575 Prefoldin beta subunit K04798 pfdB; prefoldin beta subunit D Hbut_0315 hydrogenase expression/synthesis hypA family K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF D Hbut_0314 hydrogenase/urease nickel incorporation protein, GTPase K04652 hypB; hydrogenase nickel incorporation protein HypB D Hbut_1557 putative FKBP-type peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D Hbut_1122 predicted Thioredoxin K03671 TXN; thioredoxin D Hbut_0700 Thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:hbu04131] D Hbut_0549 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Hbut_0300 ATPases of AAA+ class, SpoVK, putative cell division K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_1358 ATP-dependent protease K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_0265 Oxyanion-translocating ATPase, ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_0806 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_0807 hypothetical protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_1603 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Hbut_0985 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hbut_1581 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha C 04121 Ubiquitin system [BR:hbu04121] D Hbut_0579 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Hbut_0435 30S ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Hbut_0929 30S ribosomal protein S3e K02983 RP-S30e; small subunit ribosomal protein S30e C 03051 Proteasome [BR:hbu03051] D Hbut_0568 proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Hbut_1564 proteasome beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Hbut_1567 proteasome beta precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Hbut_1140 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit C 03032 DNA replication proteins [BR:hbu03032] D Hbut_0018 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1645 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen D Hbut_1286 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1366 Endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Hbut_0421 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Hbut_1135 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Hbut_1329 predicted pseudouridine synthase K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] D Hbut_0841 predicted ERCC4-type nuclease K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D Hbut_0449 ERCC4-type nuclease K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D Hbut_0890 conserved archaeal protein K02316 dnaG; DNA primase [EC:2.7.7.101] D Hbut_0595 Cdc6-1 K10725 cdc6A; archaeal cell division control protein 6 D Hbut_0909 Cdc6-2 K10725 cdc6A; archaeal cell division control protein 6 D Hbut_0903 minichromosome maintenance complex K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Hbut_1644 probable DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D Hbut_1102 conserved archaeal protein K18882 priL; DNA primase large subunit D Hbut_0904 conserved crenarchaeal protein K09723 ginS; DNA replication factor GINS D Hbut_0844 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Hbut_0896 DNA polymerase III K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Hbut_1274 DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Hbut_0906 Replication factor C large subunit K04800 rfcL; replication factor C large subunit D Hbut_0961 Type II DNA topoisomerase VI subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2] D Hbut_0960 Type II DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2] D Hbut_0916 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Hbut_0931 Reverse gyrase 2 K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-] D Hbut_0218 Reverse gyrase 1 K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-] C 03036 Chromosome and associated proteins [BR:hbu03036] D Hbut_1135 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Hbut_1301 conserved archaeal protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-] D Hbut_1546 possible integrase K04763 xerD; integrase/recombinase XerD D Hbut_1284 nucleotide binding protein 2 K03593 mrp; ATP-binding protein involved in chromosome partitioning C 03400 DNA repair and recombination proteins [BR:hbu03400] D Hbut_1117 predicted 6-O-methylguanine DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D Hbut_0585 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D Hbut_0266 predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Hbut_0018 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1645 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen D Hbut_1286 DNA polymerase sliding clamp subunit K04802 PCNA; proliferating cell nuclear antigen D Hbut_1366 Endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Hbut_0421 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Hbut_0917 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 D Hbut_0064 XPD/Rad3 related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] D Hbut_0841 predicted ERCC4-type nuclease K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D Hbut_0449 ERCC4-type nuclease K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D Hbut_0875 universally conserved protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Hbut_1424 predicted ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Hbut_0857 Deoxycytidine deaminase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Hbut_0091 predicted Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Hbut_1039 predicted Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Hbut_1565 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7] D Hbut_1193 predicted Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50 D Hbut_1192 predicted DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11 D Hbut_0652 universally conserved protein K15342 cas1; CRISP-associated protein Cas1 D Hbut_0967 DNA repair and recombination protein K04483 radA; DNA repair protein RadA D Hbut_1638 DNA repair and recombination protein radB K04484 radB; DNA repair protein RadB D Hbut_1279 Holliday junction resolvase K03552 hjr; holliday junction resolvase [EC:3.1.21.10] D Hbut_1191 universally conserved protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D Hbut_0916 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Hbut_0975 ATP dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D Hbut_0941 ATP dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D Hbut_1290 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D Hbut_0854 predicted ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Hbut_1218 conserved archaeal protein K22585 nreA; DNA repair protein NreA C 03029 Mitochondrial biogenesis [BR:hbu03029] D Hbut_1308 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Hbut_0556 RNase P, Rpp14 family K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Hbut_0555 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Hbut_0889 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hbut_1241 Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hbut_0050 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Hbut_1178 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hbut_0832 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Hbut_1120 glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Hbut_1284 nucleotide binding protein 2 K03593 mrp; ATP-binding protein involved in chromosome partitioning D Hbut_1202 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:hbu02000] D Hbut_0375 ABC-type molybdate transport system, periplasmic component, ModA K02020 modA; molybdate transport system substrate-binding protein D Hbut_0376 ABC-type molybdate transport system, permease component, ModB K02018 modB; molybdate transport system permease protein D Hbut_0377 ABC (ATP-binding cassette) transporter domain K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Hbut_0335 ABC-type tungstate transport system, permease component, TupB K05772 tupA; tungstate transport system substrate-binding protein D Hbut_0334 ABC-type tungstate transport system, periplasmic component, TupA K05773 tupB; tungstate transport system permease protein D Hbut_0333 predicted ABC transporter K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6] D Hbut_0067 ABC-type Fe3+ transport system, periplasmic component K02012 afuA; iron(III) transport system substrate-binding protein D Hbut_0406 ABC-type Fe3+ transport permease, ThiP K02011 afuB; iron(III) transport system permease protein D Hbut_0066 ABC-type Fe3+ transport - permease K02011 afuB; iron(III) transport system permease protein D Hbut_0065 ABC-type, ATP binding, spermidine/spermine transporter, PotA K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D Hbut_0326 Thiamine-binding, periplasmic protein K02064 thiB; thiamine transport system substrate-binding protein D Hbut_0325 ABC-type iron(III) transport system, permease component K02063 thiP; thiamine transport system permease protein D Hbut_1453 predicted ABC transporter K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Hbut_1452 predicted transporter K02050 ABC.SN.P; NitT/TauT family transport system permease protein D Hbut_1451 Nitrate transport ATP-binding protein K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein D Hbut_0308 Maltose/maltodextrin import ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Hbut_0812 predicted ABC transporter K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Hbut_1463 predicted transporter K17237 inoE; inositol-phosphate transport system substrate-binding protein D Hbut_1464 ABC-type sugar transport system K17238 inoF; inositol-phosphate transport system permease protein D Hbut_1465 ABC-type sugar transport system K17239 inoG; inositol-phosphate transport system permease protein D Hbut_1466 Maltose/maltodextrin import ATP-binding protein K17240 inoK; inositol-phosphate transport system ATP-binding protein D Hbut_1418 predicted ABC transporter K07335 bmpA; basic membrane protein A and related proteins D Hbut_0298 uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Hbut_1416 predicted ABC transporter K23535 nupB; general nucleoside transport system permease protein D Hbut_0097 ABC-type uncharacterized transport, permease K23535 nupB; general nucleoside transport system permease protein D Hbut_1415 predicted ABC transporter K23536 nupC; general nucleoside transport system permease protein D Hbut_0096 ABC-transporter, permease component K23536 nupC; general nucleoside transport system permease protein D Hbut_0098 ribose ABC transporter ATP-binding protein, RbsA-1 K23537 nupA; general nucleoside transport system ATP-binding protein D Hbut_1417 predicted ABC transporter K23537 nupA; general nucleoside transport system ATP-binding protein D Hbut_0311 ABC-type sugar transport system, periplasmic component K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Hbut_0310 ABC-type sugar transport system, permease K02025 ABC.MS.P; multiple sugar transport system permease protein D Hbut_0309 ABC-type sugar transport system, permease K02026 ABC.MS.P1; multiple sugar transport system permease protein D Hbut_0634 ABC-type phosphate transport, periplasmic protein K02040 pstS; phosphate transport system substrate-binding protein D Hbut_0635 ABC-type phosphate transport, permease K02037 pstC; phosphate transport system permease protein D Hbut_0636 ABC-type phosphate transport, permease K02038 pstA; phosphate transport system permease protein D Hbut_0637 phosphate import ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Hbut_0616 ABC-type branched-chain amino acid transport, periplasmic component K01999 livK; branched-chain amino acid transport system substrate-binding protein D Hbut_0614 High-affinity branched-chain amino acid transport ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D Hbut_0613 High-affinity branched-chain amino acid transport ATP-binding protein F K01996 livF; branched-chain amino acid transport system ATP-binding protein D Hbut_0685 glutamine-binding periplasmic protein precursor K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D Hbut_0688 glutamine transport system permease protein glnP K02029 ABC.PA.P; polar amino acid transport system permease protein D Hbut_0686 glutamate/aspartate transport system permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein D Hbut_0687 glutamine transport ATP-binding protein P K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D Hbut_0824 conserved archaeal protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Hbut_0609 ABC-type dipeptide transport, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Hbut_0608 ABC-type dipeptide/oligopeptide transport system, permease K02033 ABC.PE.P; peptide/nickel transport system permease protein D Hbut_0607 ABC-type dipeptide/oligopeptide/nickel transport system, permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Hbut_0606 Oligopeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Hbut_1535 Oligopeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Hbut_0605 Oligopeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D Hbut_0822 oppF; Oligopeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D Hbut_0171 predicted iron III ABC transporter, periplasmic substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D Hbut_0172 predicted ABC-type transport K02015 ABC.FEV.P; iron complex transport system permease protein D Hbut_0174 ABC (ATP-binding cassette) transporter nucleotide-binding domain K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D Hbut_0241 hypothetical protein K02009 cbiN; cobalt/nickel transport protein D Hbut_0240 putative cobalt transport protein K02008 cbiQ; cobalt/nickel transport system permease protein D Hbut_0242 ABC-type Co2+ transport, permease (CbiM) K02007 cbiM; cobalt/nickel transport system permease protein D Hbut_0239 ABC-type cobalt transport system, ATPase (CbiO) K02006 cbiO; cobalt/nickel transport system ATP-binding protein D Hbut_0364 ABC-type metal ion transport system, periplasmic component K02077 ABC.ZM.S; zinc/manganese transport system substrate-binding protein D Hbut_0365 ABC-type Mn2+/Zn2+ transport system, permease component K02075 ABC.ZM.P; zinc/manganese transport system permease protein D Hbut_1486 predicted ABC transporter K02075 ABC.ZM.P; zinc/manganese transport system permease protein D Hbut_0363 predicted ABC transporter K02074 ABC.ZM.A; zinc/manganese transport system ATP-binding protein D Hbut_0231 ABC transporter, ATP binding K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Hbut_1512 predicted ABC transporter K02195 ccmC; heme exporter protein C D Hbut_0850 conserved archaeal protein K01992 ABC-2.P; ABC-2 type transport system permease protein D Hbut_0105 ABC-type Na+ efflux pump, permease K01992 ABC-2.P; ABC-2 type transport system permease protein D Hbut_1437 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D Hbut_1438 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D Hbut_0104 ABC-type uncharacterized transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Hbut_0849 predicted ABC transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Hbut_1439 predicted ABC transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Hbut_0259 ABC transporter, ATP binding K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Hbut_1513 predicted ABC transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Hbut_0902 predicted ABC transporter K02004 ABC.CD.P; putative ABC transport system permease protein D Hbut_0900 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Hbut_0523 predicted ABC transporter K09013 sufC; Fe-S cluster assembly ATP-binding protein D Hbut_1021 predicted ABC transporter K09013 sufC; Fe-S cluster assembly ATP-binding protein D Hbut_0282 Na+-driven multidrug efflux pump, NorM K26937 dinF; MATE family, multidrug efflux pump D Hbut_0622 Calcium-gated potassium channel K10716 kch; voltage-gated potassium channel D Hbut_1038 predicted Divalent cation transporter K06213 mgtE; magnesium transporter D Hbut_0548 hypothetical protein K03298 TC.DME; drug/metabolite transporter, DME family D Hbut_0286 hypothetical membrane protein K03298 TC.DME; drug/metabolite transporter, DME family D Hbut_0514 Trk-type K+ transport system, membrane component K03498 trkH; trk/ktr system potassium uptake protein D Hbut_0912 predicted K+ transport system protein K03499 trkA; trk/ktr system potassium uptake protein D Hbut_0425 Voltage-gated chloride channel protein K03281 clcA; chloride channel protein, CIC family D Hbut_0846 conserved archaeal protein K03281 clcA; chloride channel protein, CIC family D Hbut_0265 Oxyanion-translocating ATPase, ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_0806 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_0807 hypothetical protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Hbut_1374 hypothetical protein K24180 mleP; malate permease and related proteins D Hbut_1436 universally conserved protein K09125 yhhQ; queuosine precursor transporter D Hbut_1267 predicted transporter protein K05595 marC; multiple antibiotic resistance protein D Hbut_0164 predicted FeoA domain - Fe2+ transport K04758 feoA; ferrous iron transport protein A D Hbut_0162 Ferrous iron transport protein K04759 feoB; ferrous iron transport protein B D Hbut_1292 conserved crenarchaeal protein K25503 cedB; DNA import protein CedB D Hbut_1291 conserved crenarchaeal protein K25504 cedA; DNA import protein CedA D Hbut_1514 hypothetical protein K02198 ccmF; cytochrome c-type biogenesis protein CcmF C 02044 Secretion system [BR:hbu02044] D Hbut_1099 predicted Type II/IV secretion system protein K07332 flaI; archaeal flagellar protein FlaI D Hbut_0213 TypeII/TypeIV secretory system protein, ATPase K07332 flaI; archaeal flagellar protein FlaI D Hbut_0958 universally conserved protein K07332 flaI; archaeal flagellar protein FlaI D Hbut_0212 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ D Hbut_1100 conserved crenarchaeal protein K07333 flaJ; archaeal flagellar protein FlaJ D Hbut_0969 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Hbut_1323 Preprotein translocase subunit secY K03076 secY; preprotein translocase subunit SecY D Hbut_1662 Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Hbut_1602 Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor D Hbut_1603 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Hbut_0106 Signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19 D Hbut_1509 mttA/Hcf106 K03116 tatA; sec-independent protein translocase protein TatA D Hbut_0264 Sec-independent secretion pathway protein K03116 tatA; sec-independent protein translocase protein TatA D Hbut_1508 predicted Sec-independent protein secretion pathway component TatC K03118 tatC; sec-independent protein translocase protein TatC C 02042 Bacterial toxins C 02022 Two-component system [BR:hbu02022] C 02035 Bacterial motility proteins [BR:hbu02035] D Hbut_1099 predicted Type II/IV secretion system protein K07332 flaI; archaeal flagellar protein FlaI D Hbut_0213 TypeII/TypeIV secretory system protein, ATPase K07332 flaI; archaeal flagellar protein FlaI D Hbut_0958 universally conserved protein K07332 flaI; archaeal flagellar protein FlaI D Hbut_0212 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ D Hbut_1100 conserved crenarchaeal protein K07333 flaJ; archaeal flagellar protein FlaJ D Hbut_0969 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:hbu04812] D Hbut_0536 universally conserved protein K06990 MEMO1; MEMO1 family protein D Hbut_1421 predicted dioxygenase K06990 MEMO1; MEMO1 family protein C 04147 Exosome [BR:hbu04147] D Hbut_0911 Enolase (2-phosphoglycerate dehydratase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hbut_0940 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Hbut_0985 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hbut_0228 Peroxiredoxin family K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D Hbut_1581 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D Hbut_0840 elongation factor 2 K03234 EEF2; elongation factor 2 D Hbut_1366 Endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Hbut_0435 30S ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Hbut_0300 ATPases of AAA+ class, SpoVK, putative cell division K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_1358 ATP-dependent protease K13525 VCP; transitional endoplasmic reticulum ATPase D Hbut_1528 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Hbut_1132 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Hbut_1324 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Hbut_0299 predicted purine phosphoribosyl transferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Hbut_0304 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Hbut_0305 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Hbut_1195 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hbut_1386 Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Hbut_1061 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hbut_0861 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Hbut_0946 Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:hbu02048] D Hbut_0652 universally conserved protein K15342 cas1; CRISP-associated protein Cas1 D Hbut_0650 conserved crenarchaeal protein K09951 cas2; CRISPR-associated protein Cas2 D Hbut_0651 conserved archaeal protein K19085 csa1; CRISPR-associated protein Csa1 D Hbut_0644 conserved uncharacterized archaeal protein K19074 csa2; CRISPR-associated protein Csa2 D Hbut_0646 hypothetical protein K07725 csa3; CRISPR-associated protein Csa3 D Hbut_0657 hypothetical protein K07725 csa3; CRISPR-associated protein Csa3 D Hbut_0649 putative RecB nuclease K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D Hbut_0944 conserved archaeal protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D Hbut_0643 hypothetical protein K19089 cas5a_b_c; CRISPR-associated protein Cas5a/b/c D Hbut_0714 hydrolase of HD superfamily K19076 cmr2; CRISPR-associated protein Cmr2 D Hbut_0710 DNA repair (RAMP superfamily) K09000 cmr4; CRISPR-associated protein Cmr4 D Hbut_0713 DNA repair (RAMP superfamily) K19142 cmr6; CRISPR-associated protein Cmr6 D Hbut_0709 DNA repair enzyme K19143 csx1; CRISPR-associated protein Csx1 D Hbut_1135 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Hbut_0120 transcriptional regulator K07746 parD1_3_4; antitoxin ParD1/3/4 D Hbut_0542 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hbut_0719 nucleic acid-binding protein, PIN domain, Zn-ribbon module K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:hbu04090] C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:hbu03100] D Hbut_0623 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hbut_0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hbut_1049 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hbut_1609 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1273 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1163 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1176 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1009 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hbut_1127 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Hbut_1664 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Hbut_0086 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Hbut_1617 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Hbut_0833 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Hbut_1590 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hbut_0143 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hbut_0387 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hbut_0525 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hbut_0139 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hbut_0003 tRNA-His K14226 tRNA-His; tRNA His D Hbut_1023 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Hbut_0011 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_0385 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_1629 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_0379 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_1351 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hbut_1017 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Hbut_1489 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Hbut_1616 tRNA-Met K14230 tRNA-Met; tRNA Met D Hbut_1129 tRNA-Met K14230 tRNA-Met; tRNA Met D Hbut_1118 tRNA-Met K14230 tRNA-Met; tRNA Met D Hbut_0526 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Hbut_1619 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hbut_1160 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hbut_0384 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_1331 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_1583 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_0477 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hbut_1114 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hbut_0058 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hbut_0461 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hbut_1131 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Hbut_0465 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Hbut_0473 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_0369 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_0135 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_0074 tRNA-Val K14237 tRNA-Val; tRNA Val D Hbut_1672 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hbut_1671 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hbut_0653 SRSR cluster K01980 23SrRNA; 23S ribosomal RNA D Hbut_0717 SRSR cluster K01980 23SrRNA; 23S ribosomal RNA D Hbut_0882 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Hbut_1388 7S ribosomal RNA K01983 ffs; SRP RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Hbut_1625 indolepyruvate oxidoreductase subunit iorA K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] D Hbut_1455 indolepyruvate oxidoreductase subunit K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] D Hbut_1626 indolepyruvate oxidoreductase K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8] D Hbut_1456 indolepyruvate oxidoreductase subunit iorB K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8] D Hbut_0802 NADH oxidase K18367 CoADR; CoA-dependent NAD(P)H sulfur oxidoreductase [EC:1.8.1.18] D Hbut_1161 Superoxide reductase K05919 dfx; superoxide reductase [EC:1.15.1.2] D Hbut_1245 predicted Fe-S osidoreductase K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5] D Hbut_0630 pyruvate-formate lyase-activating enzyme, PflA K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Hbut_0136 pyruvate-formate lyase-activating enzyme - conserved archaeal protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Hbut_0327 pyruvate-formate lyase-activating enzyme, PflA K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Hbut_0492 pyruvate-formate lyase-activating enzyme, PflA K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Hbut_1247 uncharacterized Fe-S protein K04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Hbut_0632 protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Hbut_0128 predicted Diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98] D Hbut_1095 glycosyltransferase K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D Hbut_0040 Deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D Hbut_1537 predicted CDP-alcohol phosphatidyltransferase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39] D Hbut_0196 A1pp, Appr-1-p processing enzyme K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106] D Hbut_1011 universally conserved protein K18700 flK; fluoroacetyl-CoA thioesterase [EC:3.1.2.29] D Hbut_0260 phosphohistidine phosphatase, SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-] D Hbut_0866 hypothetical protein K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-] D Hbut_1244 predicted DNase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Hbut_1101 conserved archaeal protein K07503 nucS; endonuclease [EC:3.1.-.-] D Hbut_0227 predicted polysaccharide deacetylase family K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D Hbut_0603 predicted amidohydrolase K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128] D Hbut_1669 predicted amidohydrolase K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128] D Hbut_0217 YjgH/F family protein - putative translation initiation inhibitor K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D Hbut_1265 ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Hbut_1493 putative MoxR ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Hbut_0160 universally conserved protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3] D Hbut_0933 conserved archaeal protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D Hbut_0445 conserved archaeal protein, unknown function K01741 E4.2.99.18; DNA-(apurinic or apyrimidinic site) lyase [EC:4.2.99.18] D Hbut_1561 RNA 3'-terminal phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4] D Hbut_1550 conserved archaeal protein K07468 K07468; DNA/RNA ligase [EC:6.5.1.-] C 99981 Carbohydrate metabolism D Hbut_1522 Sugar fermentation stimulation protein K06206 sfsA; sugar fermentation stimulation protein A D Hbut_0601 Sugar fermentation stimulation protein A K06206 sfsA; sugar fermentation stimulation protein A D Hbut_0949 universally conserved protein K00782 lldG; L-lactate dehydrogenase complex protein LldG C 99982 Energy metabolism D Hbut_1054 hypothetical protein K02379 fdhD; FdhD protein D Hbut_0448 Ferredoxin K05337 fer; ferredoxin D Hbut_1380 hypothetical protein K02573 napG; ferredoxin-type protein NapG D Hbut_1381 Polyferredoxin K02574 napH; ferredoxin-type protein NapH C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism D Hbut_1096 conserved archaeal protein K07027 K07027; glycosyltransferase 2 family protein C 99987 Cofactor metabolism C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D Hbut_1139 conserved archaeal protein K03627 MBF1; putative transcription factor D Hbut_0930 DNA/RNA-binding protein Alba 1 K03622 ssh10b; archaea-specific DNA-binding protein D Hbut_0977 DNA/RNA-binding protein Alba 1 K03622 ssh10b; archaea-specific DNA-binding protein D Hbut_1570 putative snRNP Sm protein K04796 RUXX; small nuclear ribonucleoprotein D Hbut_0084 putative snRNP Sm-like protein K04796 RUXX; small nuclear ribonucleoprotein D Hbut_1429 universally conserved protein K07743 K07743; transcriptional regulator D Hbut_0117 predicted transcriptional regulator K07744 K07744; transcriptional regulator D Hbut_1223 conserved archaeal protein K07745 K07745; transcriptional regulator D Hbut_0493 putative transcriptional regulator K07745 K07745; transcriptional regulator C 99974 Translation D Hbut_1658 conserved archaeal protein K07572 K07572; putative nucleotide binding protein D Hbut_0474 putative exoribonuclease K07577 K07577; putative mRNA 3-end processing factor D Hbut_1119 conserved crenarchaeal protein K07577 K07577; putative mRNA 3-end processing factor D Hbut_1651 hypothetical protein K07579 K07579; putative methylase D Hbut_1353 predicted Zn-ribbon RNA-binding protein K07580 K07580; Zn-ribbon RNA-binding protein D Hbut_0554 conserved archaeal protein K07581 K07581; RNA-binding protein C 99975 Protein processing D Hbut_1055 hypothetical protein K02380 fdhE; FdhE protein D Hbut_0754 predicted hydrogenase maturation factor K04653 hypC; hydrogenase expression/formation protein HypC D Hbut_0755 hydrogenase expression/formation protein hypD K04654 hypD; hydrogenase expression/formation protein HypD D Hbut_1031 hydrogenase expression/formation protein K04655 hypE; hydrogenase expression/formation protein HypE D Hbut_0753 hydrogenase maturation protein K04656 hypF; hydrogenase maturation protein HypF D Hbut_0471 putative RNA modification enzyme K07398 K07398; conserved protein with predicted RNA binding PUA domain D Hbut_0118 Membrane-bound serine protease (ClpP class) K07403 nfeD; membrane-bound serine protease (ClpP class) C 99976 Replication and repair D Hbut_0402 RuvB-like 2 K07472 TIP49; TBP-interacting protein D Hbut_0479 translin family, DNA-binding protein K07477 K07477; translin C 99979 Viral proteins C 99998 Others B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D Hbut_0226 Na+ dependent transporter (SNF family) K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family C 99978 Cell growth D Hbut_1262 hypothetical protein K06384 spoIIM; stage II sporulation protein M C 99993 Cell motility D Hbut_0329 hypothetical protein K23255 pilA; archaeal type IV pilus assembly protein PilA C 99995 Signaling proteins D Hbut_0809 Carbon starvation protein K06200 cstA; carbon starvation protein D Hbut_0013 Thr/Ser protein kinase K07176 K07176; putative serine/threonine protein kinase D Hbut_0210 RecA-like ATPase (KaiC-like) K08482 kaiC; circadian clock protein KaiC D Hbut_0633 kaiC; putative RecA ATPase K08482 kaiC; circadian clock protein KaiC D Hbut_1596 DNA-binding protein K06875 PDCD5; programmed cell death protein 5 C 99992 Structural proteins C 99994 Others D Hbut_0998 predicted phosphate regulatory protein K02039 phoU; phosphate transport system protein D Hbut_1018 Periplasmic divalent cation tolerance protein cutA K03926 cutA; periplasmic divalent cation tolerance protein B B 09194 Poorly characterized C 99996 General function prediction only D Hbut_1278 conserved archaeal protein K06865 K06865; ATPase D Hbut_1259 conserved archaeal protein K06874 K06874; zinc finger protein D Hbut_1068 predicted helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein D Hbut_0102 tRNA-binding protein - N-terminal MetRS K06878 K06878; tRNA-binding protein D Hbut_0596 predicted hydrolase (HAD superfamily) K07025 K07025; putative hydrolase of the HAD superfamily D Hbut_0522 universally conserved protein K09014 sufB; Fe-S cluster assembly protein SufB D Hbut_1022 predicted ABC transporter K09014 sufB; Fe-S cluster assembly protein SufB D Hbut_1554 hypothetical protein K07038 K07038; inner membrane protein D Hbut_1263 conserved archaeal protein K07049 K07049; TatD-related deoxyribonuclease D Hbut_0491 phosphoribosyltransferase K07100 K07100; putative phosphoribosyl transferase D Hbut_1632 conserved crenarchaeal protein K07143 K07143; UPF0148 protein D Hbut_1088 hypothetical protein K08975 K08975; putative membrane protein C 99997 Function unknown D Hbut_0470 Archaeal enzymes of ATP-grasp superfamily K06869 K06869; uncharacterized protein D Hbut_1082 conserved archaeal protein K06869 K06869; uncharacterized protein D Hbut_0090 Archaeal serine protease K06870 K06870; uncharacterized protein D Hbut_0368 Archaeal serine protease K06870 K06870; uncharacterized protein D Hbut_0236 phosphohydrolase - HD superfamily K06885 K06885; uncharacterized protein D Hbut_0775 universally conserved protein K06885 K06885; uncharacterized protein D Hbut_0756 conserved archaeal protein K06933 K06933; uncharacterized protein D Hbut_1613 universally conserved protein K06934 K06934; uncharacterized protein D Hbut_0274 Fe-S oxidoreductase K06935 K06935; uncharacterized protein D Hbut_1112 conserved archaeal protein K06940 K06940; uncharacterized protein D Hbut_1300 hypothetical protein K06940 K06940; uncharacterized protein D Hbut_0059 putative Fe-S oxidoreductase K06940 K06940; uncharacterized protein D Hbut_1198 universally conserved protein K06950 K06950; uncharacterized protein D Hbut_0271 phosphoesterase, ICC-like protein K06953 K06953; uncharacterized protein D Hbut_1121 conserved archaeal protein K06971 K06971; uncharacterized protein D Hbut_0023 methyl transferase K06983 K06983; uncharacterized protein D Hbut_1108 conserved archaeal protein K07022 K07022; uncharacterized protein D Hbut_1408 conserved archaeal protein K07022 K07022; uncharacterized protein D Hbut_0521 conserved uncharacterized protein K07033 K07033; uncharacterized protein D Hbut_1568 predicted exonuclease K07041 K07041; uncharacterized protein D Hbut_1359 conserved archaeal protein K07064 K07064; uncharacterized protein D Hbut_0324 predicted nucleic acid binding protein K07064 K07064; uncharacterized protein D Hbut_0760 conserved archaeal protein K07064 K07064; uncharacterized protein D Hbut_0665 nucleic acid binding, PIN domain K07065 K07065; uncharacterized protein D Hbut_1529 conserved archaeal protein K07068 K07068; uncharacterized protein D Hbut_0892 predicted nucleotidyltransferase K07073 K07073; uncharacterized protein D Hbut_1668 universally conserved protein K07090 K07090; uncharacterized protein D Hbut_0693 phosphoesterase K07095 K07095; uncharacterized protein D Hbut_0257 phosphoesterase K07096 K07096; uncharacterized protein D Hbut_0424 predicted phosphoesterase K07096 K07096; uncharacterized protein D Hbut_0980 hypothetical protein K07096 K07096; uncharacterized protein D Hbut_0446 predicted phosphohydrolase, DHH superfamily K07097 K07097; uncharacterized protein D Hbut_0696 hypothetical protein K07097 K07097; uncharacterized protein D Hbut_0483 predicted phosphoribosyltransferase K07101 K07101; uncharacterized protein D Hbut_0080 phosphoribosyltransferase K07101 K07101; uncharacterized protein D Hbut_0925 universally conserved protein K07108 K07108; uncharacterized protein D Hbut_0893 conserved archaeal protein K07129 K07129; uncharacterized protein D Hbut_0175 conserved archaeal protein K07131 K07131; uncharacterized protein D Hbut_0362 predicted RNA-binding protein, C-terminal EMAP domain K07135 K07135; uncharacterized protein D Hbut_0440 hypothetical protein K07158 K07158; uncharacterized protein D Hbut_0452 universally conserved protein K09003 K09003; uncharacterized protein D Hbut_1490 conserved archaeal protein K09120 K09120; uncharacterized protein D Hbut_1150 conserved archaeal protein K09122 K09122; uncharacterized protein D Hbut_1232 universally conserved protein K09129 K09129; uncharacterized protein D Hbut_1179 hypothetical protein K09131 K09131; uncharacterized protein D Hbut_0789 conserved archaeal protein K09133 K09133; uncharacterized protein D Hbut_0349 conserved archaeal protein/domain of unknown function K09138 K09138; uncharacterized protein D Hbut_0395 AMMECR1 family protein K09141 K09141; uncharacterized protein D Hbut_0447 hypothetical protein K09147 K09147; uncharacterized protein D Hbut_1085 conserved archaeal protein K09148 K09148; uncharacterized protein D Hbut_0988 conserved archaeal protein K09149 K09149; uncharacterized protein D Hbut_0356 conserved uncharacterized archaeal protein K09149 K09149; uncharacterized protein D Hbut_0082 conserved archaeal protein K09150 K09150; uncharacterized protein D Hbut_0281 conserved crenarchaeal protein K09157 K09157; uncharacterized protein D Hbut_0389 uncharacterized conserved archaeal protein K09715 K09715; uncharacterized protein D Hbut_1631 conserved archaeal protein K09721 K09721; uncharacterized protein D Hbut_0101 conserved archaeal protein K09732 K09732; uncharacterized protein D Hbut_0337 uncharacterized protein conserved in archaea K09736 K09736; uncharacterized protein D Hbut_0032 conserved archaeal protein K09737 K09737; uncharacterized protein D Hbut_0283 conserved archaeal protein, DUF371 K09738 K09738; uncharacterized protein D Hbut_1649 hypothetical protein K09742 K09742; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 29, 2024