+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Haemophilus influenzae R2866 (nontypeable)</h2>
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A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    R2866_1319 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    R2866_0316 murB; UDP-N-acetylenolpyruvoylglucosamine reductase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    R2866_1262 murC; UDP-N-acetylmuramate--L-alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    R2866_1265 murD; UDP-N-acetylmuramoylalanine-D-glutamate ligase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    R2866_1268 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase	K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] 
C    R2866_1261 ddlB; D-alanine--D-alanine ligase	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
B  Racemase
C    R2866_1110 alr; Alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    R2866_0709 murI; Glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
B  Glycosyltransferase
C    R2866_1266 mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase E	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    R2866_1263 murG; Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
B  Flippase
C    R2866_1417 murJ; Peptidoglycan lipid II flippase	K03980 murJ; putative peptidoglycan lipid II flippase 
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A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    R2866_0135 ponA; Penicillin-binding protein 1A (PBP 1a)	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
C    R2866_0732 ponB; Penicillin-binding protein 1B	K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] 
B  DD-Transpeptidase (Class B PBP)
C    R2866_0673 mrdA; Penicillin-binding protein 2	K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] 
C    R2866_1269 ftsI; Peptidoglycan synthetase FtsI	K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    R2866_0676 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
C    R2866_0920 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] 
C    R2866_0211 pbp7; Putative penicillin-binding protein 7	K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-] 
B  Glycosyltransferase
C    R2866_1562 mtgA; biosynthetic peptidoglycan transglycosylase	K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] 
B  Transpeptidase
C    R2866_0788 ycbB; Putative murein L,D-transpeptidase	K21470 ycbB; L,D-transpeptidase YcbB 
B  Carboxypeptidase
B  Endopeptidase
C    R2866_0391 mepA; murein DD-endopeptidase, penicillin-insensitive	K07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-] 
C    R2866_0802 spr; Putative lipoprotein Spr	K13694 mepS; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13] 
C    R2866_0164 nlpD; Probable metallopeptidase	K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] 
B  Sortase
B  Lytic transglycosylase
C    R2866_1564 Putative soluble lytic murein transglycosylase	K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
C    R2866_0474 mltA; Membrane-bound lytic murein transglycosylase A	K08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29] 
C    R2866_1635 mltC; Membrane-bound lytic murein transglycosylase C	K08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29] 
C    R2866_0350 mltF; Probable membrane-bound lytic murein transglycosylase F	K18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29] 
C    R2866_0116 yceG; Conserved hypothetical protein	K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] 
C    R2866_0675 rlpA; Rare lipoprotein A-like protein	K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
B  Amidase
C    R2866_0638 amiB; N-acetylmuramoyl-L-alanine amidase	K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
C    R2866_0279 ampD; N-acetyl-anhydromuramyl-L-alanine amidase AmpD	K03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28] 
B  Structural protein
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#Last updated: January 30, 2024