+F Repair protein KO
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DNA Repair and Recombination Proteins - Kosakonia cowanii
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BWI95_15685 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BWI95_12340 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E BWI95_00580 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BWI95_06365 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BWI95_15515 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D BWI95_01805 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BWI95_09690 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BWI95_08375 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BWI95_15685 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BWI95_20820 bifunctional transcriptional regulator/O6-methylguanine-DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D BWI95_12340 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D BWI95_20815 alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E BWI95_00580 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BWI95_06880 double-stranded uracil-DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E BWI95_20220 DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E BWI95_06365 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BWI95_08750 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E BWI95_08400 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E BWI95_12365 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E BWI95_15515 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E BWI95_15035 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E BWI95_20665 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E BWI95_00675 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E BWI95_06075 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E BWI95_08335 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E BWI95_21850 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E BWI95_01270 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E BWI95_03960 ABC-ATPase UvrA K03701 uvrA; excinuclease ABC subunit A
E BWI95_16290 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E BWI95_12655 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E BWI95_19385 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E BWI95_15075 endonuclease K05984 cho; excinuclease Cho [EC:3.1.25.-]
E BWI95_22760 DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BWI95_01270 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E BWI95_08335 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E BWI95_21850 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F BWI95_00750 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F BWI95_00745 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F BWI95_09925 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F BWI95_08325 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F BWI95_14375 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E BWI95_05480 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E BWI95_03380 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E BWI95_05700 DNA mismatch repair protein MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E BWI95_19935 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E BWI95_00260 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E BWI95_11025 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E BWI95_19025 exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E BWI95_07975 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E BWI95_02935 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E BWI95_12110 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E BWI95_14295 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E BWI95_10080 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BWI95_11410 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E BWI95_02360 DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E BWI95_19020 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E BWI95_08335 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E BWI95_21850 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E BWI95_22760 DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BWI95_03955 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BWI95_09570 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E BWI95_19660 very short patch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E BWI95_05635 exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E BWI95_05645 exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E BWI95_05630 exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E BWI95_05135 DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E BWI95_19110 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BWI95_19105 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BWI95_19125 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E BWI95_17105 hypothetical protein K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E BWI95_00965 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E BWI95_03250 primosomal replication protein N K02686 priB; primosomal replication protein N
E BWI95_11395 primosomal replication protein N'' K04067 priC; primosomal replication protein N''
E BWI95_02445 primosomal protein DnaI K02317 dnaT; DNA replication protein DnaT
E BWI95_19935 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E BWI95_10780 exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E BWI95_10785 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E BWI95_05135 DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E BWI95_02280 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E BWI95_07980 DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E BWI95_08310 DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BWI95_06075 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E BWI95_00510 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E BWI95_11420 recombination protein RecR K06187 recR; recombination protein RecR
E BWI95_04545 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E BWI95_10770 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E BWI95_19110 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BWI95_19105 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BWI95_19125 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E BWI95_20760 ATP-dependent helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E BWI95_10780 exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E BWI95_10785 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F BWI95_20855 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BWI95_07985 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F BWI95_17415 DNA topoisomerase I subunit omega K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F BWI95_00665 DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
F BWI95_11120 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F BWI95_18980 exodeoxyribonuclease K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
F BWI95_17195 DNA recombinase K07455 recT; recombination protein RecT
F BWI95_06075 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F BWI95_00510 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F BWI95_11420 recombination protein RecR K06187 recR; recombination protein RecR
F BWI95_08335 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F BWI95_21850 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F BWI95_07665 fis; Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F BWI95_15195 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F BWI95_13435 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F BWI95_19935 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F BWI95_22725 DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BWI95_03960 ABC-ATPase UvrA K03701 uvrA; excinuclease ABC subunit A
F BWI95_16290 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F BWI95_12655 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F BWI95_11670 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BWI95_17575 transcriptional regulator K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D BWI95_10345 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D BWI95_15695 DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D BWI95_22480 DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D BWI95_18460 hypothetical protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D BWI95_18750 hypothetical protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D BWI95_16930 hypothetical protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D BWI95_15700 hypothetical protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D BWI95_22475 protein impA K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D BWI95_05135 DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
D BWI95_04045 repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D BWI95_04545 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D BWI95_02000 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D BWI95_03955 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BWI95_14090 DNA damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D BWI95_05130 recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D BWI95_22945 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D BWI95_13660 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D BWI95_18555 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D BWI95_12790 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D BWI95_01805 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BWI95_09690 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BWI95_08375 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D BWI95_05020 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BWI95_20870 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BWI95_05025 class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D BWI95_20875 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024