+F Repair protein KO #

  DNA Repair and Recombination Proteins - Micromonospora terminaliae

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D GCE86_25460 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D GCE86_21395 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D GCE86_26785 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E GCE86_21785 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E GCE86_05370 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E GCE86_23855 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E GCE86_24120 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E GCE86_28085 helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D GCE86_17880 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_26550 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_21290 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_06470 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_16440 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_21640 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_21645 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_26155 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_09520 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_13860 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_06065 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_02155 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D GCE86_25460 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D GCE86_21395 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D GCE86_26785 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D GCE86_19145 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13] C BER (base exicision repair) D DNA glycosylases E GCE86_21785 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E GCE86_15815 G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28] E GCE86_29995 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E GCE86_01815 UdgX family uracil-DNA binding protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E GCE86_21390 helix-turn-helix domain-containing protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E GCE86_05370 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E GCE86_23855 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E GCE86_28760 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E GCE86_25035 Fpg/Nei family DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E GCE86_00935 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E GCE86_01730 Fpg/Nei family DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E GCE86_28555 formamidopyrimidine-DNA glycolase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E GCE86_24120 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E GCE86_04270 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] E GCE86_02805 endonuclease/exonuclease/phosphatase family protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] E GCE86_16910 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] E GCE86_25425 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] E GCE86_30485 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7] D RecJ D DNA ligase E GCE86_00515 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E GCE86_16245 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E GCE86_16050 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A E GCE86_16205 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B E GCE86_16040 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C E GCE86_21570 pcrA; DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E GCE86_21055 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E GCE86_21130 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E GCE86_16245 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E GCE86_00515 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F GCE86_22235 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F GCE86_22230 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F GCE86_22045 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F GCE86_05160 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F GCE86_29905 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases E GCE86_29845 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E GCE86_29840 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E GCE86_04790 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E GCE86_25600 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E GCE86_18165 MerR family transcriptional regulator K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E GCE86_18960 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E GCE86_27815 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E GCE86_17105 DEDD exonuclease domain-containing protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E GCE86_24460 DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E GCE86_00515 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E GCE86_21570 pcrA; DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E GCE86_21055 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E GCE86_21130 AAA family ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E GCE86_19595 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E GCE86_25415 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E GCE86_01865 recA; recombinase RecA K03553 recA; recombination protein RecA E GCE86_04905 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA E GCE86_04910 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E GCE86_04900 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E GCE86_05175 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E GCE86_02485 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 E GCE86_02490 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11 D RecFOR pathway proteins E GCE86_01865 recA; recombinase RecA K03553 recA; recombination protein RecA E GCE86_23830 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms E GCE86_25610 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF E GCE86_00885 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E GCE86_18815 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E GCE86_24450 recR; recombination protein RecR K06187 recR; recombination protein RecR E GCE86_05680 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) E GCE86_04905 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA E GCE86_04910 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E GCE86_04900 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins E GCE86_02485 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 E GCE86_02490 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11 C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex E GCE86_28005 Ku protein K10979 ku; DNA end-binding protein Ku E GCE86_11915 DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] E GCE86_31385 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] E GCE86_28010 DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] E GCE86_28015 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] E GCE86_20440 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F GCE86_03850 DNA topoisomerase 4 subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F GCE86_25640 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F GCE86_03845 DNA topoisomerase IV subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F GCE86_25635 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F GCE86_27785 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1] F GCE86_04565 DNA topoisomerase IB K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F GCE86_00780 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F GCE86_18815 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F GCE86_24450 recR; recombination protein RecR K06187 recR; recombination protein RecR F GCE86_00515 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F GCE86_16030 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F GCE86_04580 RecQ family ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F GCE86_22515 RecQ family ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F GCE86_16050 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A F GCE86_16205 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D GCE86_16785 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D GCE86_12135 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D GCE86_01865 recA; recombinase RecA K03553 recA; recombination protein RecA D GCE86_01960 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D GCE86_05680 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D GCE86_16810 DNA polymerase Y family protein K14161 imuB; protein ImuB D GCE86_16805 dnaE; DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D GCE86_19595 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D GCE86_25415 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D GCE86_01870 RecX family transcriptional regulator K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D GCE86_23285 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D GCE86_01745 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D GCE86_17880 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_26550 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_21290 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_06470 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_16440 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_21640 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_21645 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_26155 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_09520 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_13860 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_06065 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D GCE86_00790 NUDIX domain-containing protein K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69] D GCE86_05720 NUDIX domain-containing protein K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D GCE86_02155 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D GCE86_01970 vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] C Others D GCE86_01515 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024